647 results on '"Guddat, Luke W."'
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2. Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches
3. Development of Prolinol Containing Inhibitors of Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design
4. An oligopeptide permease, OppABCD, requires an iron–sulfur cluster domain for functionality
5. Structural basis of resistance to herbicides that target acetohydroxyacid synthase
6. Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster
7. Structural Characterization of Enzymatic Interactions with Functional Nicotinamide Cofactor Biomimetics.
8. High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
9. Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators
10. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria
11. Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity
12. Inhibition of M. tuberculosisand human ATP synthase by BDQ and TBAJ-587
13. Mapping of the Reaction Trajectory Catalyzed by Class I Ketol-Acid Reductoisomerase.
14. Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF
15. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels
16. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors
17. Structure–activity relationships of bensulfuron methyl and its derivatives as novel agents against drug‐resistant Candida auris
18. Structures of fungal and plant acetohydroxyacid synthases
19. An electron transfer path connects subunits of a mycobacterial respiratory supercomplex
20. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
21. Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation
22. Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis
23. Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse
24. Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2
25. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
26. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur
27. Structural insights into substrate recognition by the type VII secretion system
28. Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase
29. Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases
30. Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics
31. Structure–activity relationships of bensulfuron methyl and its derivatives as novel agents against drug‐resistant Candida auris.
32. Cryo-EM structures of a prokaryotic heme transporter CydDC.
33. Structural basis of resistance to herbicides that target acetohydroxyacid synthase
34. Targeting acetohydroxyacid synthase to discover new therapeutics for Cryptococcus neoformans infections
35. Acetohydroxyacid synthase: structure, function, regulation and inhibition
36. Structural investigation of two commercial herbicides that target acetohydroxyacid synthase
37. Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC
38. Structural insights into trehalose capture and translocation by mycobacterial LpqY-SugABC
39. Structural insights into the mechanism of inhibition of AHAS by herbicides
40. Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF
41. Discovery and evaluation of novel Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors as therapeutic drug leads
42. Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target
43. Deacidification of grass silage press juice by continuous production of acetoin from its lactate via an immobilized enzymatic reaction cascade
44. Phosphate Forms an Unusual Tripodal Complex with the Fe-Mn Center of Sweet Potato Purple Acid Phosphatase
45. Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families
46. Structure of the human ATP synthase
47. Structure of the human respiratory complex II
48. Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase
49. Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs
50. Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases
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