717 results on '"Guddat, Luke W."'
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2. Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587
3. Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2
4. Optimization of an α-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches
5. A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors
6. In search of herbistasis: COT-metsulfuron methyl displays rare herbistatic properties.
7. Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster
8. Structural basis of resistance to herbicides that target acetohydroxyacid synthase
9. Structural basis for the broad substrate specificity of two acyl-CoA dehydrogenases FadE5 from mycobacteria
10. Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity
11. Coupling of N7-methyltransferase and 3′-5′ exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading
12. High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
13. Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis
14. Chemical Synthesis, Herbicidal Activity, Crop Safety, and Molecular Basis of ortho-Fluoroalkoxy Substituted Sulfonylureas as Novel Acetohydroxyacid Synthase Inhibitors.
15. Inherent symmetry and flexibility in hepatitis B virus subviral particles.
16. Cryo-EM structures of a mycobacterial ABC transporter that mediates rifampicin resistance.
17. Inhibition studies of ketol-acid reductoisomerases from pathogenic microorganisms
18. Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO
19. Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase
20. Design and development of ((4-methoxyphenyl)carbamoyl) (5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl)amide analogues as Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors
21. Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops
22. Adaptation of a continuous, calorimetric kinetic assay to study the agmatinase-catalyzed hydrolytic reaction
23. Development of Prolinol Containing Inhibitors of Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase: Rational Structure-Based Drug Design
24. An oligopeptide permease, OppABCD, requires an iron–sulfur cluster domain for functionality
25. Structures of fungal and plant acetohydroxyacid synthases
26. Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse
27. Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB2-AcpM2
28. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
29. Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur
30. Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF
31. Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels
32. Sulfide, sulfoxide and sulfone bridged acyclic nucleoside phosphonates as inhibitors of the Plasmodium falciparum and human 6-oxopurine phosphoribosyltransferases: Synthesis and evaluation
33. Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis
34. Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators
35. Structural Characterization of Enzymatic Interactions with Functional Nicotinamide Cofactor Biomimetics.
36. Crystal Structures of Membrane Transporter MmpL3, an Anti-TB Drug Target
37. An electron transfer path connects subunits of a mycobacterial respiratory supercomplex
38. Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
39. Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase
40. Acyclic nucleoside phosphonates with unnatural nucleobases, favipiravir and allopurinol, designed as potential inhibitors of the human and Plasmodium falciparum 6-oxopurine phosphoribosyltransferases
41. Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics
42. Structural insights into substrate recognition by the type VII secretion system
43. Discovery and evaluation of novel Mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors as therapeutic drug leads
44. Phosphate Forms an Unusual Tripodal Complex with the Fe-Mn Center of Sweet Potato Purple Acid Phosphatase
45. Structural insights into the mechanism of inhibition of AHAS by herbicides
46. Structure–activity relationships of bensulfuron methyl and its derivatives as novel agents against drug‐resistant Candida auris
47. Deacidification of grass silage press juice by continuous production of acetoin from its lactate via an immobilized enzymatic reaction cascade
48. Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs
49. Oligomeric state of hypoxanthine−guanine phosphoribosyltransferase from Mycobacterium tuberculosis
50. The Role of a FAD Cofactor in the Regulation of Acetohydroxyacid Synthase by Redox Signaling Molecules
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