Search

Your search keyword '"Guglielmino, M. R."' showing total 10 results
Start Over Author "Guglielmino, M. R."
Sorry, I don't understand your search. ×
10 results on '"Guglielmino, M. R."'

2. Specific Alterations of the MicroRNA Transcriptome, its Target Proteome, and Global Network Structure in CRC after Treatment with MAPKs inhibitors

Author

Ragusa, Marco, Statello, L, Majorana, A, Maugeri, M, Barbagallo, Davide, Duro, L. R., Guglielmino, M. R., Angelica, R, Salito, L, Santonocito, M, Sammito, M, Cavallaro, A, Scalia, M, Caltabiano, Rosario, Privitera, Giuseppe, Biondi, Antonio Giuseppe, Di Vita, M, Cappellani, A, Vasquez, E, Lanzafame, Salvatore, Tendi, E, Mishra, B, DI PIETRO, Cinzia Santa, Basile, Francesco, and Purrello, Michele

Published
2011

5. Complex Systems Biology: Structural, Functional and Pathological Genomics of the Apoptotic Machinery and Identification of Candidate Genes for Breast Adenocarcinoma, Thyroid Carcinoma and Neuroblastoma

Author

DI PIETRO, Cinzia Santa, Ragusa, Marco, Duro, L., D’Agostino, V., Triberio, P., Barbagallo, D., Di Cataldo, A., Destri, Li, Laganà, A., Forte, S., Pernagallo, S., Valenti, S., Guglielmino, M. R., Maniscalchi, T., Giugno, R., Pulvirenti, Alfredo, Santagati, M., Russo, G., Scalia, Marina, Bernardini, Renato, Guccione, S., Pavone, L., Messina, A., Stefani, S., Ferro, A., Grzeschik, K. H., and Purrello, M.

Published
2006

6. The Apoptotic Machinery As A Biological Complex System: An Omics Analysis and Identification of Candidate Genes for Breast Adenocarcinoma, Thyroid Carcinoma and Neuroblastoma

Author

DI PIETRO, Cinzia Santa, Ragusa, Marco, Duro, L., Dagostino, V., Triberio, P, Barbagallo, Davide, DI CATALDO, A., Li, G., Destri, Lagan, A., Forte, S., Pernagallo, S., Valenti, S., Guglielmino, M. R., Maniscalchi, T., Giugno, R., Pulvirenti, A., Santagati, Maria Carmela, Russo, G., Scalia, Marina, Bernardini, Renato, Guccione, S., Pavone, L., Stefani, S., Ferro, Alfredo, Grzeschik, K. H., and Purrello, Michele

Published
2006

10. Expression analysis of TFIID in single human oocytes: new potential molecular markers of oocyte quality.

Author

Di Pietro, C., Vento, M., Ragusa, M., Barbagallo, D., Guglielmino, M. R., Maniscalchi, T., Duro, L. R., Tomasello, L., Majorana, A., De Palma, A., Borzi, P., Scollo, P., and Purrello, M.

Subjects
*TRANSCRIPTION factors, *OVUM, *BIOMARKERS, *MESSENGER RNA, *PROTEINS, *GENES, *CARRIER proteins
Abstract

Molecular characterization of human female gametes should make it easier to understand the basis of certain infertility disorders. Biologically significant mRNAs have been analysed in single oocytes to search for molecular biomarkers of oocyte quality. Initial analysis was focused on mRNA for proteins involved in cell growth and cycle control, specifically those encoding members of the general transcription apparatus such as the subunits of the general transcription factor TFIID. This heteromultimeric protein, comprising about 15 subunits, is the most important general transcription factor of the second class. These proteins are essential for the initiation of transcription of protein-coding genes, so they must be present in mature oocytes for mRNA synthesis during the first phases of embryonic development. Semi-quantitative reverse transcription-polymerase chain reaction was used to identify different TFIID subunits in single oocytes and to search for differences in expression as compared with control tissues. The data show that the mRNAs for most TFIID subunits are indeed synthesized in oocytes, but their expression profiles differ markedly. TATA box-binding protein associated factor 4B (TAF4B), TAF5 and TATA box-binding protein-like 2 (TBPL2) are expressed at higher levels in oocytes than in control tissues. It is suggested that they could be used as biomarkers of oocyte quality. [ABSTRACT FROM AUTHOR]

Published
2008
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results