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Objective: To study the preventive effects of Fructus Phyllanthiin (FP) alone and combined with tea polyphenols (FP-TP) or L-carnitine (FP-LC) on high-fat diet-induced obesity in rats. Methods: The experimental, model control and positive control groups were fed a high-fat diet while the negative control group was fed a normal diet. Meanwhile, the experimental group was gavaged with FP, FP-TP or FP-LC for seven weeks. At the end of the gavage period, body mass, perirenal fat mass and peritesticular fat mass were measured, and four items of blood lipid tests in serum and liver lipid levels were detected. The levels of serum leptin, resistin and lipocalin were measured, and the activities of related enzymes and total protein levels in the liver and mRNA expression in adipose tissues were measured to observe the effects of FP and its combination with TP or LC on obesity alleviation and protection against liver injury in experimentally obese rats. Results: The body mass and body fat content of the rats in the model control group increased significantly when compared with the negative control group (P < 0.001). The rats in the FP and FP-LC intervention groups showed significant decreases in body mass, and perirenal fat and peritesticular fat contents and indexes. The levels of total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) in the serum and liver decreased significantly, and the level of high-density lipoprotein cholesterol (HDL-C) increased significantly. Moreover, serum leptin and resistin levels significantly dropped, and lipocalin levels increased; the activities of alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT) and the content of malondialdehyde (MDA) in the liver decreased, and the activity of superoxide dismutase (SOD) increased; the mRNA expression of adenosine 5’-monophosphate-activated protein kinase (AMPK) α-2 was significantly up-regulated in adipose tissues. On the other hand, FP-TP intervention had no significant anti-obesity effect. Conclusion: FP can prevent high-fat diet-induced obesity in rats, being more effective when used alone than when combined with TP or LC.

In order to verify the effectiveness and feasibility of the combination of motion capture technology and teaching, based on dance teaching, this paper proposes a dance posture analysis method based on feature vector matching and applies it to dance teaching.. The main research work includes the following: (1) according to the characteristics of human motion poses-free editing, extracting human skeleton models, establishing a human motion model database, analysing the application of motion capture systems in dance training, and proposing a method of feature plane similarity matching to calculate model components and motion parameters. After verification, the method has high accuracy and robustness for the analysis of human posture, so that dancers can accurately compare the differences with standard dance movements, and provide theoretical support for scientific dance training. (2) Aiming at the complexity of learning dance, a dance teaching method based on motion capture technology is proposed. Using motion capture technology, a whole complex dance movement is decomposed into many small segments to make a teaching animation, which guides students to learn based on small dance movement. Imitation makes the abstract theory vivid, intuitive and easy to understand, which is conducive for the innovation of education and teaching methods.

Thyroid cancer is one of the most malignant tumors and a serious threat to human health. Selenium (Se) is an essential trace element that is critical for thyroid function. Since the relationship between Se and thyroid cancer remains unclear, a meta-analysis was performed to clarify the relationship. A total of five databases (PubMed, Web of Science, Scopus, Embase and Cochrane library) were searched for case-control studies and cohort studies on serum levels of Se and thyroid cancer published up to 13 July 2022. Seven articles consisting of 10 case-control studies and comprised of 2,205 subjects met the inclusion criteria for meta-analysis. From the 10 selected studies, pooled analysis indicated that thyroid cancer patients had lower serum levels of Se than healthy controls [standardized mean difference = −1.25, 95% confidence interval = (−2.07, −0.44), P = 0.003]. Our meta-analysis supports a significant relationship between serum levels of Se and thyroid cancer. [ABSTRACT FROM AUTHOR]