1. Value of fine-needle aspiration in evaluating large thyroid nodules
- Author
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Christian Debry, Agnès Dupret-Bories, Pierre-Philippe Volkmar, Thibaut Raguin, Eric Sauleau, Guillaume Debonnecaze, Jean-Pierre Ghnassia, Olivier Schneegans, and Jean-François Rodier
- Subjects
Thyroid nodules ,medicine.medical_specialty ,Large thyroid ,medicine.medical_treatment ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,medicine ,skin and connective tissue diseases ,medicine.diagnostic_test ,business.industry ,Thyroid ,Thyroidectomy ,Cancer ,Retrospective cohort study ,medicine.disease ,3. Good health ,body regions ,surgical procedures, operative ,Fine-needle aspiration ,medicine.anatomical_structure ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Predictive value of tests ,Radiology ,business ,Nuclear medicine - Abstract
Background The American Thyroid Association (ATA) recommends using ultrasound-guided fine-needle aspiration (FNA) in order to evaluate supracentimetric and suspect thyroid nodules. The purpose of this study was to evaluate the effective use of FNA before surgery for nodules over 3 cm in diameter. Methods In this retrospective study, we analyzed the results of ultrasound-guided FNA and postoperative histological analysis in 843 nodules >3 cm. Results The FNA was informative in 42.6%. The correlation with the final histological analysis was 94.8% for benign nodules and 71.0% for malignant nodules. The FNA had a positive predictive value of 71%, a specificity of 97%, a sensitivity of 56%, and a 4.7% rate of false-negative results. Conclusion Because there is a nonnegligible FNA risk of error, notably allowing the evolution of a cancer in 1 of 20 cases, the FNA data should not delay surgical intervention for potentially suspect nodules >3 cm in diameter. © 2016 Wiley Periodicals, Inc. Head Neck 39: 32–36, 2017
- Published
- 2016
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