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Two new Cu(II) complexes namely, Cu(PDC)2.H2O (1) and {[Cu(1,3-BIP)(PDC)(NO3)]·2H2O}n (2) (1,3-BIP = 1,3-di(1H-imidazol-1-yl)propane; HPDC = 5-methyl-4-oxo-1-phenyl-1,4-dihydropyridazine-3-carboxylic acid) have been sythesized and characterized by single crystal x-ray ananlyses, thermogravietr -ic techniques. The single-crystal x-ray diffraction reveals that complex 1 shows a zero-dimensional structure, which is further reinforced through strong intermolecular hydrogen bonding to form a 3D suparmolecular framework. Complex 2 exhibits a one-dimensional ring structure, which are further linked by intermolecular hydrogen bonding to form a 3D supermolecular architecture. The optimized geometric bond lengths and bond angles of complex 1 obtained by using density functional theory (DFT) have been compared with X-ray diffraction values. In addition, the antimicrobial activity of the complex 1 and the photocatalytic activity of the complex 2 were also investigated. [ABSTRACT FROM AUTHOR]

Oceans contain many freshwater resources and metal elements that people need, so the rational development of marine resources can solve the two major problems of shortage of freshwater resources and metal elements for people. To solve these two challenges, a system was designed to obtain freshwater resources and metallic elements simultaneously. An ion enrichment module was added to the conventional flow capacitor deionization system to collect metal elements while the seawater was deionized. A flowing electrode allows the metal elements to enter the flowing electrode through the desalination ability. It transports the metal elements to the enrichment module through the fluidity of the fluid while reducing the ion concentration at the flowing electrode, thus reducing the effect caused by the rejection of the same ion and collecting and enriching the metal elements. We purchased activated carbon to test the feasibility of the system with different mass fractions of activated carbon suspensions. The results showed that the elemental enrichment capacity of the system increased from 12.291 to 14.795 mg, and the enrichment rate increased from 13.536 to 16.294 mg cm -2 h -1 as the mass fraction of activated carbon increased. Thus, the system accomplished the goals of desalination and metal collection simultaneously.

Rosmarinic acid,a hydrosoluble polyphenolic hydroxyl compound,is the active ingredient in such traditional Chinese medicines as Menthae Haplocalycis Herba,Salviae Miltiorrhizae Radix et Rhizoma,Rosemary,Perillae Folium. Because of its good anti-inflammatory,anti-oxidant and anti-tumor effects,it is widely used in food,medicine and other fields. However,the metabolic process and metabolites of rosmarinic acid in vivo have not been completely defined. In this study,an efficient method of ultra-high performance liquid chromatography combined with linear ion trap-Orbitrap(UHPLC-LTQ-Orbitrap) mass spectrometer was used to analyze the metabolites in vivo of rosmarinic acid in rats. Plasma,urine and feces samples were collected after oral administration of rosmarinic acid. After biological samples were processed by solid phase extraction,Acquity UPLC  BEH C18 column(2. 1 mm × 100 mm,1. 7 μm) was used with 0. 1% formic acid(A)-acetonitrile(B) solution as the mobile phase at the speed of 0. 30 m L·min-1 and temperature of 35 ℃ under gradient conditions. The plasma,urine,feces and the blank samples were then analyzed by ESI-LTQ-Orbitrap under both negative and positive ion modes. Based on the accurate mass measurement(<5),MS/MS fragmentation patterns,standards and literatures,a total of 36 metabolites were screened out and identified in the biological samples collected from rats after intragastric administration. Three were identified 3 from rat plasma,31 from urine,and 7 from feces. The main metabolic pathways of rosmarinic acid in rats can be divided into five parts. Rosmarinic acid were first decomposed into small molecules,such as trans-caffeic acid,coumaric acid,m-hydroxybenzoic acid and Danshensu,which were followed by sulfation,methylation,glucuronic acid conjugation and glucose conjugation. The results showed that UHPLC-LTQ-Orbitrap mass spectrometer could be used to analyze the metabolism of rosmarinic acid in rats,and provide reference for further studies on toxicology,pharmacodynamics and secondary development of Chinese medicine.