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21 results on '"Guo, Yueqi"'

1. Multiply robust estimation for causal survival analysis with treatment noncompliance

Author

Cheng, Chao, Guo, Yueqi, Liu, Bo, Wruck, Lisa, and Li, Fan

Subjects
Statistics - Methodology, Statistics - Applications
Abstract

Comparative effectiveness research frequently addresses a time-to-event outcome and can require unique considerations in the presence of treatment noncompliance. Motivated by the challenges in addressing noncompliance in the ADAPTABLE pragmatic trial, we develop a multiply robust estimator to estimate the principal survival causal effects under the principal ignorability and monotonicity assumption. The multiply robust estimator involves several working models including that for the treatment assignment, the compliance strata, censoring, and time-to-event of interest. The proposed estimator is consistent even if one, and sometimes two, of the working models are misspecified. We apply the multiply robust method in the ADAPTABLE trial to evaluate the effect of low- versus high-dose aspirin assignment on patients' death and hospitalization from cardiovascular diseases. We find that, comparing to low-dose assignment, assignment to the high-dose leads to differential effects among always high-dose takers, compliers, and always low-dose takers. Such treatment effect heterogeneity contributes to the null intention-to-treatment effect, and suggests that policy makers should design personalized strategies based on potential compliance patterns to maximize treatment benefits to the entire study population. We further perform a formal sensitivity analysis for investigating the robustness of our causal conclusions under violation of two identification assumptions specific to noncompliance.

Published
2023

2. Neuromatch Academy: Teaching Computational Neuroscience with global accessibility

Author

van Viegen, Tara, Akrami, Athena, Bonnen, Kate, DeWitt, Eric, Hyafil, Alexandre, Ledmyr, Helena, Lindsay, Grace W., Mineault, Patrick, Murray, John D., Pitkow, Xaq, Puce, Aina, Sedigh-Sarvestani, Madineh, Stringer, Carsen, Achakulvisut, Titipat, Alikarami, Elnaz, Atay, Melvin Selim, Batty, Eleanor, Erlich, Jeffrey C., Galbraith, Byron V., Guo, Yueqi, Juavinett, Ashley L., Krause, Matthew R., Li, Songting, Pachitariu, Marius, Straley, Elizabeth, Valeriani, Davide, Vaughan, Emma, Vaziri-Pashkam, Maryam, Waskom, Michael L., Blohm, Gunnar, Kording, Konrad, Schrater, Paul, Wyble, Brad, Escola, Sean, and Peters, Megan A. K.

Subjects
Quantitative Biology - Other Quantitative Biology
Abstract

Neuromatch Academy designed and ran a fully online 3-week Computational Neuroscience summer school for 1757 students with 191 teaching assistants working in virtual inverted (or flipped) classrooms and on small group projects. Fourteen languages, active community management, and low cost allowed for an unprecedented level of inclusivity and universal accessibility., Comment: 10 pages, 3 figures. Equal contribution by the executive committee members of Neuromatch Academy: Tara van Viegen, Athena Akrami, Kate Bonnen, Eric DeWitt, Alexandre Hyafil, Helena Ledmyr, Grace W. Lindsay, Patrick Mineault, John D. Murray, Xaq Pitkow, Aina Puce, Madineh Sedigh-Sarvestani, Carsen Stringer. and equal contribution by the board of directors of Neuromatch Academy: Gunnar Blohm, Konrad Kording, Paul Schrater, Brad Wyble, Sean Escola, Megan A. K. Peters

Published
2020

3. Neuromatch Academy: Teaching Computational Neuroscience with Global Accessibility

Author

Academy, Neuromatch, van Viegen, Tara, Akrami, Athena, Bonnen, Kathryn, DeWitt, Eric, Hyafil, Alexandre, Ledmyr, Helena, Lindsay, Grace W, Mineault, Patrick, Murray, John D, Pitkow, Xaq, Puce, Aina, Sedigh-Sarvestani, Madineh, Stringer, Carsen, Achakulvisut, Titipat, Alikarami, Elnaz, Atay, Melvin Selim, Batty, Eleanor, Erlich, Jeffrey C, Galbraith, Byron V, Guo, Yueqi, Juavinett, Ashley L, Krause, Matthew R, Li, Songting, Pachitariu, Marius, Straley, Elizabeth, Valeriani, Davide, Vaughan, Emma, Vaziri-Pashkam, Maryam, Waskom, Michael L, Blohm, Gunnar, Kording, Konrad, Schrater, Paul, Wyble, Brad, Escola, Sean, and Peters, Megan AK

Subjects
Neurosciences, Networking and Information Technology R&D (NITRD), Humans, Neuromatch Academy, Python coding, accessibility, computational neuroscience, data science, education, inclusivity, q-bio.OT, Information and Computing Sciences, Medical and Health Sciences, Psychology and Cognitive Sciences, Experimental Psychology
Abstract

Neuromatch Academy (NMA) designed and ran a fully online 3-week Computational Neuroscience Summer School for 1757 students with 191 teaching assistants (TAs) working in virtual inverted (or flipped) classrooms and on small group projects. Fourteen languages, active community management, and low cost allowed for an unprecedented level of inclusivity and universal accessibility.

Published
2021

14. Neuromatch Academy: a 3-week, online summer school in computational neuroscience

Author

’t Hart, Bernard, primary, Achakulvisut, Titipat, additional, Adeyemi, Ayoade, additional, Akrami, Athena, additional, Alicea, Bradly, additional, Alonso-Andres, Alicia, additional, Alzate-Correa, Diego, additional, Ash, Arash, additional, Ballesteros, Jesus, additional, Balwani, Aishwarya, additional, Batty, Eleanor, additional, Beierholm, Ulrik, additional, Benjamin, Ari, additional, Bhalla, Upinder, additional, Blohm, Gunnar, additional, Blohm, Joachim, additional, Bonnen, Kathryn, additional, Brigham, Marco, additional, Brunton, Bingni, additional, Butler, John, additional, Caie, Brandon, additional, Gajic, N, additional, Chatterjee, Sharbatanu, additional, Chavlis, Spyridon, additional, Chen, Ruidong, additional, Cheng, You, additional, Chow, H.m., additional, Chua, Raymond, additional, Dai, Yunwei, additional, David, Isaac, additional, DeWitt, Eric, additional, Denis, Julien, additional, Dipani, Alish, additional, Dorschel, Arianna, additional, Drugowitsch, Jan, additional, Dwivedi, Kshitij, additional, Escola, Sean, additional, Fan, Haoxue, additional, Farhoodi, Roozbeh, additional, Fei, Yicheng, additional, Fiquet, Pierre-Étienne, additional, Fontolan, Lorenzo, additional, Forest, Jeremy, additional, Fujishima, Yuki, additional, Galbraith, Byron, additional, Galdamez, Mario, additional, Gao, Richard, additional, Gjorgjieva, Julijana, additional, Gonzalez, Alexander, additional, Gu, Qinglong, additional, Guo, Yueqi, additional, Guo, Ziyi, additional, Gupta, Pankaj, additional, Gurbuz, Busra, additional, Haimerl, Caroline, additional, Harrod, Jordan, additional, Hyafil, Alexandre, additional, Irani, Martin, additional, Jacobson, Daniel, additional, Johnson, Michelle, additional, Jones, Ilenna, additional, Karni, Gili, additional, Kass, Robert, additional, Kim, Hyosub, additional, Kist, Andreas, additional, Koene, Randal, additional, Kording, Konrad, additional, Krause, Matthew, additional, Kumar, Arvind, additional, Kühn, Norma, additional, Lc, Ray, additional, Laporte, Matthew, additional, Lee, Junseok, additional, Li, Songting, additional, Lin, Sikun, additional, Lin, Yang, additional, Liu, Shuze, additional, Liu, Tony, additional, Livezey, Jesse, additional, Lu, Linlin, additional, Macke, Jakob, additional, Mahaffy, Kelly, additional, Martins, A, additional, Martorell, Nicolás, additional, Martínez, Manolo, additional, Mattar, Marcelo, additional, Menendez, Jorge, additional, Miller, Kenneth, additional, Mineault, Patrick, additional, Mohammadi, Nosratullah, additional, Mohsenzadeh, Yalda, additional, Morgenroth, Elenor, additional, Morshedzadeh, Taha, additional, Mosberger, Alice, additional, Muliya, Madhuvanthi, additional, Mur, Marieke, additional, Murray, John, additional, Nd, Yashas, additional, Naud, Richard, additional, Nayak, Prakriti, additional, Oak, Anushka, additional, Castillo, Itzel, additional, Orouji, Seyedmehdi, additional, Otero-Millan, Jorge, additional, Pachitariu, Marius, additional, Pandey, Biraj, additional, Paredes, Renato, additional, Parent, Jesse, additional, Park, Il, additional, Peters, Megan, additional, Pitkow, Xaq, additional, Poirazi, Panayiota, additional, Popal, Haroon, additional, Prabhakaran, Sandhya, additional, Qiu, Tian, additional, Ragunathan, Srinidhi, additional, Rodriguez-Cruces, Raul, additional, Rolnick, David, additional, Sahoo, Ashish, additional, Salehinajafabadi, Saeed, additional, Savin, Cristina, additional, Saxena, Shreya, additional, Schrater, Paul, additional, Schroeder, Karen, additional, Schwarze, Alice, additional, Sedigh-Sarvestani, Madineh, additional, Sekhar, K, additional, Shadmehr, Reza, additional, Shanechi, Maryam, additional, Sharma, Siddhant, additional, Shea-Brown, Eric, additional, Shenoy, Krishna, additional, Shimabukuro, Carolina, additional, Shuvaev, Sergey, additional, Sin, Man, additional, Smith, Maurice, additional, Steinmetz, Nicholas, additional, Stosio, Karolina, additional, Straley, Elizabeth, additional, Strandquist, Gabrielle, additional, Stringer, Carsen, additional, Tomar, Rimjhim, additional, Tran, Ngoc, additional, Triantafillou, Sofia, additional, Udeigwe, Lawrence, additional, Valeriani, Davide, additional, Valton, Vincent, additional, Vaziri-Pashkam, Maryam, additional, Vincent, Peter, additional, Vishne, Gal, additional, Wallisch, Pascal, additional, Wang, Peiyuan, additional, Ward, Claire, additional, Waskom, Michael, additional, Wei, Kunlin, additional, Wu, Anqi, additional, Wu, Zhengwei, additional, Wyble, Brad, additional, Zhang, Lei, additional, Zysman, Daniel, additional, Uquillas, Federico, additional, and van Viegen, Tara, additional

Published
2022
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15. Neuromatch Academy: Teaching Computational Neuroscience with Global Accessibility

Author

van Viegen, Tara, Akrami, Athena, Bonnen, Kathryn, DeWitt, Eric, Hyafil, Alexandre, Ledmyr, Helena, Lindsay, Grace W., Mineault, Patrick, Murray, John D., Pitkow, Xaq, Puce, Aina, Sedigh-Sarvestani, Madineh, Stringer, Carsen, Achakulvisut, Titipat, Alikarami, Elnaz, Atay, Melvin Selim, Batty, Eleanor, Erlich, Jeffrey C., Galbraith, Byron V., Guo, Yueqi, Juavinett, Ashley L., Krause, Matthew R., Li, Songting, Pachitariu, Marius, Straley, Elizabeth, Valeriani, Davide, Vaughan, Emma, Vaziri-Pashkam, Maryam, Waskom, Michael L., Blohm, Gunnar, Kording, Konrad, Schrater, Paul, Wyble, Brad, Escola, Sean, and Peters, Megan A.K.

Published
2021
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21. Multiply robust estimation of principal causal effects with noncompliance and survival outcomes.

Author

Cheng C, Guo Y, Liu B, Wruck L, Li F, and Li F

Abstract

Treatment noncompliance and censoring are two common complications in clinical trials. Motivated by the ADAPTABLE pragmatic clinical trial, we develop methods for assessing treatment effects in the presence of treatment noncompliance with a right-censored survival outcome. We classify the participants into principal strata, defined by their joint potential compliance status under treatment and control. We propose a multiply robust estimator for the causal effects on the survival probability scale within each principal stratum. This estimator is consistent even if one, sometimes two, of the four working models-on the treatment assignment, the principal strata, censoring, and the outcome-is misspecified. A sensitivity analysis strategy is developed to address violations of key identification assumptions, the principal ignorability and monotonicity. We apply the proposed approach to the ADAPTABLE trial to study the causal effect of taking low- versus high-dosage aspirin on all-cause mortality and hospitalization from cardiovascular diseases., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Published
2024
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