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2. Real-World 1-Year Outcomes of Treatment-Intensive Neovascular Age-Related Macular Degeneration Switched to Faricimab

Author

Logeswaran, Abison, Tufail, Adnan, Gurbaxani, Avinash, Pal, Bishwanath, Egan, Catherine, Bessant, David, Thomas, Dhanes, Ling, Heng, Huemer, Josef, Basheer, Khadijah, Balaskas, Konstantinos, Bouras, Konstantinos, Nicholson, Luke, Lyndon Da Cruz, Natkunarajah, Mythili, Okhravi, Narciss, Islam, Niaz, Desai, Parul, Keane, Pearse, Addison, Peter, Patel, Praveen, Rajendram, Ranjan, Hamilton, Robin, Selvam, Senthil, Esposti, Simona, Sivaprasad, Sobha, Heeren, Tjebo, Rahman, Waheeda, Khan, Yasir, Ockrim, Zoe, Saihan, Zubin, Sim, Sing Yue, Chalkiadaki, Evangelia, Koutsocheras, Georgios, Patel, Praveen J., Keane, Pearse A., and Bhatia, Bhairavi

Published
2024
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4. New Agents for Treating Dry Eye Syndrome

Author

Skalicky, Simon E., Petsoglou, Con, Gurbaxani, Avinash, Fraser, Clare L., McCluskey, Peter, Armstrong, Donald, Editor-in-chief, Babizhayev, Mark A., editor, Li, David Wan-Cheng, editor, Kasus-Jacobi, Anne, editor, Žorić, Lepša, editor, and Alió, Jorge L., editor

Published
2015
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12. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis—Report 1

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Mahajan, Sarakshi, additional, Yuen, Yew Sen, additional, Agarwal, Aniruddha, additional, Kon, Onn Min, additional, Barisani-Asenbauer, Talin, additional, Kempen, John H., additional, Gupta, Amod, additional, Jabs, Douglas A., additional, Smith, Justine R., additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, Gupta, Vishali, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Ashutosh, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Bodaghi, Bahram, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, Concha del Rio, Luz Elena, additional, Cunningham, Emmett T., additional, Land Curi, Andrè Luiz, additional, Das, Dipankar, additional, Davis, Janet, additional, DeSmet, Marc, additional, Denisova, Ekaterina, additional, Denniston, Alastair K., additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gunasekeran, Dinesh Visva, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Islam, Shah Md., additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, La Distia Nora, Rina, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, McCluskey, Peter, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R., additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Raje, Dhananjay, additional, Rathinam, S.R., additional, Rousselot, Andres, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Sen, H. Nida, additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Vasconcelos Santos, Daniel Vitor, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, and Zierhut, Manfred, additional

Published
2021
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13. Collaborative Ocular Tuberculosis Study Consensus Guidelines on the Management of Tubercular Uveitis—Report 2

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Bodaghi, Baharam, additional, Barisani-Asenbauer, Talin, additional, McCluskey, Peter, additional, Agarwal, Aniruddha, additional, Kempen, John H., additional, Gupta, Amod, additional, Smith, Justine R., additional, de Smet, Marc D., additional, Yuen, Yew Sen, additional, Mahajan, Sarakshi, additional, Kon, Onn Min, additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, Gupta, Vishali, additional, Agrawal, Rupesh, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Ashutosh, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, Concha del Rio, Luz Elena, additional, Cunningham, Emmett T., additional, Land Curi, Andrè Luiz, additional, Das, Dipankar, additional, Davis, Janet, additional, DeSmet, Marc, additional, Denisova, Ekaterina, additional, Denniston, Alastair K., additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gunasekeran, Dinesh Visva, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Islam, Shah M.d., additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, La Distia Nora, Rina, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R., additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Raje, Dhananjay, additional, Rathinam, S.R., additional, Rousselot, Andres, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Nida Sen, H., additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Vasconcelos Santos, Daniel Vitor, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, Zierhut, Manfred, additional, and Xian, Zheng, additional

Published
2021
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14. The Collaborative Ocular Tuberculosis Study (COTS) Consensus (CON) Group Meeting Proceedings

Author

Agrawal, Rupesh, primary, Testi, Ilaria, additional, Mahajan, Sarakshi, additional, Yuen, Yew Sen, additional, Agarwal, Aniruddha, additional, Rousselot, Andres, additional, Raje, Dhananjay, additional, Gunasekeran, Dinesh Visva, additional, Kon, Onn Min, additional, Barisani-Asenbauer, Talin, additional, Kempen, John H., additional, Gupta, Amod, additional, Jabs, Douglas A., additional, Smith, Justine R., additional, Bodaghi, Bahram, additional, Zierhut, Manfred, additional, DeSmet, Marc, additional, Cluskey, Peter Mc, additional, Agarwal, Mamta, additional, Agarwal, Manisha, additional, Aggarwal, Kanika, additional, Agrawal, Mukesh, additional, Al-Dhibi, Hassan, additional, Androudi, Sofia, additional, Asyari, Fatma, additional, Balasundaram, Manohar Babu, additional, Murthy, Kalpana Babu, additional, Baglivo, Edoardo, additional, Banker, Alay, additional, Bansal, Reema, additional, Basu, Soumyava, additional, Behera, Digamber, additional, Biswas, Jyotirmay, additional, Carreño, Ester, additional, Caspers, Laure, additional, Chee, Soon Phaik, additional, Chhabra, Romi, additional, Cimino, Luca, additional, del Rio, Luz Elena Concha, additional, Cunningham, Emmett T., additional, Curi, Andrè Luiz Land, additional, Das, Dipankar, additional, Denisova, Ekaterina, additional, Denniston, Alastair K, additional, Errera, Marie-Hélène, additional, Fonollosa, Alejandro, additional, George, Amala, additional, Goldstein, Debra A., additional, Crosier, Yan Guex, additional, Gurbaxani, Avinash, additional, Invernizzi, Alessandro, additional, Isa, Hazlita M., additional, Md. Islam, Shah, additional, Jones, Nicholas, additional, Katoch, Deeksha, additional, Khairallah, Moncef, additional, Khosla, Amit, additional, Kramer, Michal, additional, Kumar, Amitabh, additional, Kumar, Atul, additional, Nora, Rina La Distia, additional, Lee, Richard, additional, Lowder, Careen, additional, Luthra, Saurabh, additional, Mahendradas, Padmamalini, additional, Makhoul, Dorine, additional, Mazumdar, Shahana, additional, Mehta, Salil, additional, Miserocchi, Elisabetta, additional, Mochizuki, Manabu, additional, Mohamed, Oli S., additional, Muccioli, Cristina, additional, Munk, Marion R, additional, Murthy, Somasheila, additional, Narain, Shishir, additional, Nascimento, Heloisa, additional, Neri, Piergiorgio, additional, Nguyen, Myhanh, additional, Okada, Annabelle A., additional, Ozdal, Pinar, additional, Palestine, Alan, additional, Pichi, Francesco, additional, Rathinam, S.R, additional, Schlaen, Ariel, additional, Sehgal, Shobha, additional, Sen, H Nida, additional, Sharma, Aman, additional, Sharma, Kusum, additional, Shoughy, Samir S., additional, Singh, Nirbhai, additional, Singh, Ramandeep, additional, Soheilian, Masoud, additional, Sridharan, Sudharshan, additional, Thorne, Jennifer E., additional, Tappeiner, Christoph, additional, Teoh, Stephen, additional, Tognon, Maria Sofia, additional, Tugal-Tutkun, Ilknur, additional, Tyagi, Mudit, additional, Uy, Harvey, additional, Santos, Daniel Vitor Vasconcelos, additional, Valentincic, Natasa Vidovic, additional, Westcott, Mark, additional, Yanai, Ryoji, additional, Alvarez, Bety Yanez, additional, Zahedur, Rahman, additional, Nguyen, Quan Dong, additional, Pavesio, Carlos, additional, and Gupta, Vishali, additional

Published
2020
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16. The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery

Author

Gurbaxani, Avinash and Lawuyi,Lola

Subjects
genetic structures, Clinical Ophthalmology, sense organs, eye diseases
Abstract

Lola Elizabeth Lawuyi, Avinash Gurbaxani Moorfields Eye Hospital Dubai, Dubai, UAE Abstract: The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery compromises the visualization of the surgical field and working space for surgeons. This may lead to complications that include posterior capsular tear and associated vitreous loss, longer surgical time, and postoperative inflammation. Postoperative inflammation is often uncomfortable and frustrating for patients. It causes pain, redness, and photophobia. This compromises the best-uncorrected vision following surgery and often leads to multiple clinic visits. This article examines the literature published on the current treatments used to manage mydriasis, pain, and inflammation in cataract extraction surgery. Combination phenylephrine/ketorolac injection offers an exciting new class of medication for use in cataract surgery. With the recent approval of Omidria™ (combination of phenylephrine 1% and ketorolac 0.3%) by the US Food and Drug Administration (FDA) for intraocular use, we review the clinical utility of this new combination injection in cataract surgery. PubMed, MEDLINE, and conference proceedings were searched for the relevant literature using a combination of the following search terms: cataract extraction surgery, pupil dilation (mydriasis), miosis, phenylephrine, ketorolac, Omidria™, intracameral mydriatic. Relevant articles were reviewed and their references checked for further relevant literature. All abstracts were reviewed and full texts retrieved where available. Keywords: cataract extraction surgery, ketorolac, mydriasis, miosis, Omidria™, phenylephrine

Published
2015

17. Real-World 1-Year Outcomes of Treatment-Intensive Neovascular Age-Related Macular Degeneration Switched to Faricimab

Author

Sim, Sing Yue, Chalkiadaki, Evangelia, Koutsocheras, Georgios, Nicholson, Luke, Sivaprasad, Sobha, Patel, Praveen J., Selvam, Senthil, Pal, Bishwanath, Keane, Pearse A., Bhatia, Bhairavi, Hamilton, Robin, Logeswaran, Abison, Tufail, Adnan, Gurbaxani, Avinash, Pal, Bishwanath, Egan, Catherine, Bessant, David, Thomas, Dhanes, Ling, Heng, Huemer, Josef, Basheer, Khadijah, Balaskas, Konstantinos, Bouras, Konstantinos, Nicholson, Luke, Cruz, Lyndon Da, Natkunarajah, Mythili, Okhravi, Narciss, Islam, Niaz, Desai, Parul, Keane, Pearse, Addison, Peter, Patel, Praveen, Rajendram, Ranjan, Hamilton, Robin, Selvam, Senthil, Esposti, Simona, Sivaprasad, Sobha, Heeren, Tjebo, Rahman, Waheeda, Khan, Yasir, Ockrim, Zoe, and Saihan, Zubin

Abstract

To report 1-year anatomic and functional real-world outcomes of patients with treatment-intensive neovascular age-related macular degeneration (nAMD) switched to faricimab.

Published
2024
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19. The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery

Author

Lawuyi,Lola Elizabeth, Gurbaxani,Avinash, Lawuyi,Lola Elizabeth, and Gurbaxani,Avinash

Abstract

Lola Elizabeth Lawuyi, Avinash Gurbaxani Moorfields Eye Hospital Dubai, Dubai, UAE Abstract: The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery compromises the visualization of the surgical field and working space for surgeons. This may lead to complications that include posterior capsular tear and associated vitreous loss, longer surgical time, and postoperative inflammation. Postoperative inflammation is often uncomfortable and frustrating for patients. It causes pain, redness, and photophobia. This compromises the best-uncorrected vision following surgery and often leads to multiple clinic visits. This article examines the literature published on the current treatments used to manage mydriasis, pain, and inflammation in cataract extraction surgery. Combination phenylephrine/ketorolac injection offers an exciting new class of medication for use in cataract surgery. With the recent approval of Omidria™ (combination of phenylephrine 1% and ketorolac 0.3%) by the US Food and Drug Administration (FDA) for intraocular use, we review the clinical utility of this new combination injection in cataract surgery. PubMed, MEDLINE, and conference proceedings were searched for the relevant literature using a combination of the following search terms: cataract extraction surgery, pupil dilation (mydriasis), miosis, phenylephrine, ketorolac, Omidria™, intracameral mydriatic. Relevant articles were reviewed and their references checked for further relevant literature. All abstracts were reviewed and full texts retrieved where available. Keywords: cataract extraction surgery, ketorolac, mydriasis, miosis, Omidria™, phenylephrine

Published
2015

23. Ocular Myositis

Author

Fraser, Clare L., primary, Skalicky, Simon E., additional, Gurbaxani, Avinash, additional, and McCluskey, Peter, additional

Published
2012
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26. Ocular Allergy

Author

Gurbaxani, Avinash, primary, Calder, Virginia L., additional, and Lightman, Susan, additional

Published
2008
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27. The clinical utility of new combination phenylephrine/ketorolac injection in cataract surgery.

Author

Lawuyi, Lola Elizabeth and Gurbaxani, Avinash

Subjects
*PUPILLARY reflex, *CATARACT surgery, *EYE inflammation, *MIOSIS, *OPHTHALMIC surgery, *SURGEONS
Abstract

The maintenance of mydriasis throughout cataract extraction surgery and the control of ocular inflammation are crucial for successful surgical outcomes. The development of miosis during cataract surgery compromises the visualization of the surgical field and working space for surgeons. This may lead to complications that include posterior capsular tear and associated vitreous loss, longer surgical time, and postoperative inflammation. Postoperative inflammation is often uncomfortable and frustrating for patients. It causes pain, redness, and photophobia. This compromises the best-uncorrected vision following surgery and often leads to multiple clinic visits. This article examines the literature published on the current treatments used to manage mydriasis, pain, and inflammation in cataract extraction surgery. Combination phenylephrine/ ketorolac injection offers an exciting new class of medication for use in cataract surgery. With the recent approval of Omidria™ (combination of phenylephrine 1% and ketorolac 0.3%) by the US Food and Drug Administration (FDA) for intraocular use, we review the clinical utility of this new combination injection in cataract surgery. PubMed, MEDLINE, and conference proceedings were searched for the relevant literature using a combination of the following search terms: cataract extraction surgery, pupil dilation (mydriasis), miosis, phenylephrine, ketorolac, Omidria™, intracameral mydriatic. Relevant articles were reviewed and their references checked for further relevant literature. All abstracts were reviewed and full texts retrieved where available. [ABSTRACT FROM AUTHOR]

Published
2015
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28. Treatment of acute postoperative endophthalmitis without hospital admission: Do we dare?

Author

Gurbaxani, Avinash and Patel, Chetan K.

Subjects
HOSPITAL wards, ANTI-infective agents, CLINICAL pathology, ANTIBIOTICS
Abstract

Summary: Introduction: We report the successful management of a culture positive case of APE, without the need for hospital admission and discuss the merits of this strategy. Case: A 79-year-old lady underwent uncomplicated cataract surgery in her left eye using phacoemulsification under topical and intracameral anaesthesia. She reported to eye casualty four days later, with pain and vision reduced to 6/60 in the left eye. A diagnosis of acute postoperative endophthalmitis was made. A vitreous biopsy was performed and antibiotics injected intravitreally on the same day. The patient was discharged on oral and topical antibiotics on the same day and reviewed subsequently in the clinic as an outpatient. Vision steadily improved and at one month following intravitreal injection her vision had improved to 6/9 unaided. The cornea remained clear, with a quiet anterior chamber and a clear view of the fundus. Discussion: Current management of acute postoperative endophthalmitis in the UK includes a vitreous biopsy, administration of antibiotics into the vitreous cavity, admission of patients to a hospital ward and daily review. It is our opinion that under the circumstances where patients are fit and well, without significant co-morbidity, hospital admission is not necessary as demonstrated by the patient in our report. [Copyright &y& Elsevier]

Published
2006
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29. Standardization of Nomenclature for Ocular Tuberculosis - Results of Collaborative Ocular Tuberculosis Study (COTS) Workshop.

Author

Agrawal R, Agarwal A, Jabs DA, Kee A, Testi I, Mahajan S, McCluskey PJ, Gupta A, Palestine A, Denniston A, Banker A, Invernizzi A, Fonollosa A, Sharma A, Kumar A, Curi A, Okada A, Schlaen A, Heiligenhaus A, Kumar A, Gurbaxani A, Bodaghi B, Islam Shah B, Lowder C, Tappeiner C, Muccioli C, Vasconcelos-Santos DV, Goldstein D, Behra D, Das D, Makhoul D, Baglivo E, Denisova E, Miserocchi E, Carreno E, Asyari F, Pichi F, Sen HN, Uy H, Nascimento H, Tugal-Tutkun I, Arevalo JF, Davis J, Thorne J, Hisae Yamamoto J, Smith J, Garweg JG, Biswas J, Babu K, Aggarwal K, Cimino L, Kuffova L, Agarwal M, Zierhut M, Agarwal M, De Smet M, Tognon MS, Errera MH, Munk M, Westcott M, Soheilian M, Accorinti M, Khairallah M, Nguyen M, Kon OM, Mahendradas P, Yang P, Neri P, Ozdal P, Amer R, Lee R, Distia Nora R, Chhabra R, Belfort R, Mehta S, Shoughy S, Luthra S, Mohamed SO, Chee SP, Basu S, Teoh S, Ganesh S, Barisani-Asenbauer T, Guex-Crosier Y, Ozyazgan Y, Akova Y, Habot-Wilner Z, Kempen J, Nguyen QD, Pavesio C, and Gupta V

Abstract

Purpose : To standardize a nomenclature system for defining clinical phenotypes, and outcome measures for reporting clinical and research data in patients with ocular tuberculosis (OTB). Methods : Uveitis experts initially administered and further deliberated the survey in an open meeting to determine and propose the preferred nomenclature for terms related to the OTB, terms describing the clinical phenotypes and treatment and reporting outcomes. Results : The group of experts reached a consensus on terming uveitis attributable to tuberculosis (TB) as tubercular uveitis. The working group introduced a SUN-compatible nomenclature that also defines disease "remission" and "cure", both of which are relevant for reporting treatment outcomes. Conclusion : A consensus nomenclature system has been adopted by a large group of international uveitis experts for OTB. The working group recommends the use of standardized nomenclature to prevent ambiguity in communication and to achieve the goal of spreading awareness of this blinding uveitis entity.

Published
2020
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30. Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma.

Author

Taylor SR, Gurbaxani A, Sallam A, and Lightman S

Abstract

Purpose: A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma., Methods: Prospective, single-masked case series of 20 patients with uveitis and secondary raised intraocular pressure. Participants were divided into four groups of five patients dependent on their use of topical medication: (1) prostaglandin analogues only, (2) corticosteroids only, (3) both prostaglandin analogues and corticosteroids, (4) no topical medication. Conjunctival cells were harvested by impression cytology and were examined for inflammatory markers (CD3, CD54, HLA-DR, CCR4, CCR5) by flow cytometry. A tear fluid sample was also examined for inflammatory cytokines (IL-12p70, IL-2, IL-10, IL-8, IL-6, IL-4, IL-5, IFN-gamma, IL-1beta, IFN-alpha, IFN-beta) by multiplex bead arrays., Results: All groups demonstrated increased markers of conjunctival inflammation. There was no significant difference in levels of any inflammatory markers between the four groups, suggesting that the use of topical prostaglandin analogues does not increase conjunctival levels of inflammation beyond those already seen in uveitis., Conclusions: The use of topical prostaglandins does not appear to induce conjunctival inflammation over that which is already present in patients with uveitic glaucoma. This supports the use of topical prostaglandin analogues in patients with uveitic glaucoma, indicating that their use is unlikely to adversely affect subsequent glaucoma filtration surgery through the induction of chronic conjunctival inflammation.

Published
2012
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