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3. Use of Technogenic Raw Materials in the Technology of Ceramic Materials

Author

Buravchuk, Nina, Guryanova, Olga, Putri, E. P., Ghosh, Arindam, Series Editor, Chua, Daniel, Series Editor, de Souza, Flavio Leandro, Series Editor, Aktas, Oral Cenk, Series Editor, Han, Yafang, Series Editor, Gong, Jianghong, Series Editor, Jawaid, Mohammad, Series Editor, Parinov, Ivan A., editor, Chang, Shun-Hsyung, editor, and Soloviev, Arkady N., editor

Published
2023
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4. CD70 CXCR2-Modified CAR T-Cells Against Acute Myeloid Leukemia

Author

Ligon, John A, primary, Castillo, Paul, additional, Ma, Xiaojie, additional, Jin, Linchun, additional, Tao, Haipeng, additional, Nguyen, Duy, additional, Jobin, Gabriel, additional, Guryanova, Olga, additional, Lamba, Jatinder K, additional, Sawyer, W Greg, additional, Mitchell, Duane, additional, Mendez-Gomez, Hector, additional, Sayour, Elias, additional, and Huang, Jianping, additional

Published
2024
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6. Technological Aspects of Obtaining Fuel Composites Based on Fine-Grained Coal Waste

Author

Buravchuk, Nina, Guryanova, Olga, Putri, Erni, Ghosh, Arindam, Series Editor, Chua, Daniel, Series Editor, de Souza, Flavio Leandro, Series Editor, Aktas, Oral Cenk, Series Editor, Han, Yafang, Series Editor, Gong, Jianghong, Series Editor, Jawaid, Mohammad, Series Editor, Parinov, Ivan A., editor, Chang, Shun-Hsyung, editor, Kim, Yun-Hae, editor, and Noda, Nao-Aki, editor

Published
2021
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9. Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer

Author

Feng, Yang, primary, Yuan, Qingchen, additional, Newsome, Rachel C., additional, Robinson, Troy, additional, Bowman, Robert L., additional, Zuniga, Ashley N., additional, Hall, Kendra N., additional, Bernsten, Cassandra M., additional, Shabashvili, Daniil E., additional, Krajcik, Kathryn I., additional, Gunaratne, Chamara, additional, Zaroogian, Zachary J., additional, Venugopal, Kartika, additional, Casellas Roman, Heidi L., additional, Levine, Ross L., additional, Chatila, Walid K., additional, Yaeger, Rona, additional, Riva, Alberto, additional, Jobin, Christian, additional, Kopinke, Daniel, additional, Avram, Dorina, additional, and Guryanova, Olga A., additional

Published
2023
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10. Data from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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11. Supplementary Figure from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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12. Supplementary Data from The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, primary, Loghavi, Sanam, primary, Dolgalev, Igor, primary, Leddin, Emmett M., primary, Loo, Christian E., primary, Torabifard, Hedieh, primary, Nicolet, Deedra, primary, Wang, Jingjing, primary, Corrigan, Kate, primary, Paraskevopoulou, Varvara, primary, Starczynowski, Daniel T, primary, Wang, Eric, primary, Abdel-Wahab, Omar, primary, Viny, Aaron D, primary, Stone, Richard M., primary, Byrd, John C., primary, Guryanova, Olga A., primary, Kohli, Rahul M., primary, Cisneros, G. Andrés, primary, Tsirigos, Aristotelis, primary, Eisfeld, Ann-Kathrin, primary, Aifantis, Iannis, primary, and Guillamot, Maria, primary

Published
2023
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13. Table S1 from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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14. Table S3 (part 3) from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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15. Data from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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20. Table S3 (part 1) from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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21. Supplementary Methods, Figure Legends, Table Legends, Figures S1 - S5 from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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22. Table S3 (part 2) from Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers

Author

Glass, Jacob L., primary, Hassane, Duane, primary, Wouters, Bas J., primary, Kunimoto, Hiroyoshi, primary, Avellino, Roberto, primary, Garrett-Bakelman, Francine E., primary, Guryanova, Olga A., primary, Bowman, Robert, primary, Redlich, Shira, primary, Intlekofer, Andrew M., primary, Meydan, Cem, primary, Qin, Tingting, primary, Fall, Mame, primary, Alonso, Alicia, primary, Guzman, Monica L., primary, Valk, Peter J.M., primary, Thompson, Craig B., primary, Levine, Ross, primary, Elemento, Olivier, primary, Delwel, Ruud, primary, Melnick, Ari, primary, and Figueroa, Maria E., primary

Published
2023
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27. Supplementary Data from DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Author

Venugopal, Kartika, primary, Feng, Yang, primary, Nowialis, Pawel, primary, Xu, Huanzhou, primary, Shabashvili, Daniil E., primary, Berntsen, Cassandra M., primary, Kaur, Prabhjot, primary, Krajcik, Kathryn I., primary, Taragjini, Christina, primary, Zaroogian, Zachary, primary, Casellas Román, Heidi L., primary, Posada, Luisa M., primary, Gunaratne, Chamara, primary, Li, Jianping, primary, Dupéré-Richer, Daphné, primary, Bennett, Richard L., primary, Pondugula, Santhi, primary, Riva, Alberto, primary, Cogle, Christopher R., primary, Opavsky, Rene, primary, Law, Brian K., primary, Bhaduri-McIntosh, Sumita, primary, Kubicek, Stefan, primary, Staber, Philipp B., primary, Licht, Jonathan D., primary, Bird, Jonathan E., primary, and Guryanova, Olga A., primary

Published
2023
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30. Hematopoietic-specific heterozygous loss ofDnmt3aexacerbates colitis-associated colon cancer

Author

Feng, Yang, primary, Newsome, Rachel C, additional, Robinson, Troy, additional, Bowman, Robert L, additional, Zuniga, Ashley N, additional, Hall, Kendra N, additional, Bernsten, Cassandra M, additional, Shabashvili, Daniil E, additional, Krajcik, Kathryn I, additional, Gunaratne, Chamara, additional, Zaroogian, Zachary J, additional, Venugopal, Kartika, additional, Casellas Roman, Heidi L, additional, Levine, Ross L, additional, Chatila, Walid K, additional, Yaeger, Rona, additional, Riva, Alberto, additional, Kopinke, Daniel, additional, Jobin, Christian, additional, Avram, Dorina, additional, and Guryanova, Olga A, additional

Published
2022
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35. The Impact of Inflammation-Induced Tumor Plasticity during Myeloid Transformation

Author

Yeaton, Anna, primary, Cayanan, Geraldine, additional, Loghavi, Sanam, additional, Dolgalev, Igor, additional, Leddin, Emmett M., additional, Loo, Christian E., additional, Torabifard, Hedieh, additional, Nicolet, Deedra, additional, Wang, Jingjing, additional, Corrigan, Kate, additional, Paraskevopoulou, Varvara, additional, Starczynowski, Daniel T, additional, Wang, Eric, additional, Abdel-Wahab, Omar, additional, Viny, Aaron D, additional, Stone, Richard M., additional, Byrd, John C., additional, Guryanova, Olga A., additional, Kohli, Rahul M., additional, Cisneros, G. Andrés, additional, Tsirigos, Aristotelis, additional, Eisfeld, Ann-Kathrin, additional, Aifantis, Iannis, additional, and Guillamot, Maria, additional

Published
2022
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36. DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling

Author

Guryanova, Olga A, Shank, Kaitlyn, Spitzer, Barbara, Luciani, Luisa, Koche, Richard P, Garrett-Bakelman, Francine E, Ganzel, Chezi, Durham, Benjamin H, Mohanty, Abhinita, Hoermann, Gregor, Rivera, Sharon A, Chramiec, Alan G, Pronier, Elodie, Bastian, Lennart, Keller, Matthew D, Tovbin, Daniel, Loizou, Evangelia, Weinstein, Abby R, Gonzalez, Adriana Rodriguez, Lieu, Yen K, Rowe, Jacob M, Pastore, Friederike, McKenney, Anna Sophia, Krivtsov, Andrei V, Sperr, Wolfgang R, Cross, Justin R, Mason, Christopher E, Tallman, Martin S, Arcila, Maria E, Abdel-Wahab, Omar, Armstrong, Scott A, Kubicek, Stefan, Staber, Philipp B, Gönen, Mithat, Paietta, Elisabeth M, Melnick, Ari M, Nimer, Stephen D, Mukherjee, Siddhartha, and Levine, Ross L

Subjects
Anthracyclines -- Dosage and administration, Methyltransferases -- Research, Gene mutation -- Research, Drug resistance -- Research, Acute myelocytic leukemia -- Genetic aspects -- Drug therapy -- Research, Biological sciences, Health
Abstract

Author(s): Olga A Guryanova [1]; Kaitlyn Shank [1]; Barbara Spitzer [2]; Luisa Luciani [3]; Richard P Koche [4, 5]; Francine E Garrett-Bakelman [6]; Chezi Ganzel [7]; Benjamin H Durham [1]; [...]

Published
2016
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37. The application of information technologies for color reproduction and technical system management in printing art production

Author

Guryanova Olga, Gnibeda Artem, Filimonova Elena, Pukhova Ekaterina, and Kotelnitskaya Lubov

Subjects
Environmental sciences, GE1-350
Abstract

The article develops the process of modeling color separation in the reproduction of graphic information in printing technology, shows the management of the technical system at each stage. With the use of information technology, this complex and multi-stage technological process of color conversion is carried out automatically, which does not allow showing the clarity of technological operations.

Published
2020
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38. The Cancer Stem Cell Paradigm

Author

Eyler, Christine E., Heddleston, John M., Hitomi, Masahiro, Guryanova, Olga A., Macswords, Jennifer M., Flavahan, William A., Hjelmeland, Anita B., Rich, Jeremy N., and Phinney, Donald G., editor

Published
2011
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39. Repurposing Tranexamic Acid as an Anticancer Agent

Author

Law, Mary E., primary, Davis, Bradley J., additional, Ghilardi, Amanda F., additional, Yaaghubi, Elham, additional, Dulloo, Zaafir M., additional, Wang, Mengxiong, additional, Guryanova, Olga A., additional, Heldermon, Coy D., additional, Jahn, Stephan C., additional, Castellano, Ronald K., additional, and Law, Brian K., additional

Published
2022
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41. Dnmt3a Mutations in the Hematopoietic System Promote Colitis-Associated Colon Cancer: A Model of Clonal Hematopoiesis in Solid Tumors

Author

Feng, Yang, primary, Newsome, Rachel, additional, Robinson, Troy, additional, Bowman, Robert L., additional, Zuniga, Ashley, additional, Hall, Kendra, additional, Bernsten, Cassandra, additional, Shabashvili, Daniil, additional, Krajcik, Kathryn, additional, Gunaratne, Chamara, additional, Zaroogian, Zachary, additional, Venugopal, Kartika, additional, Casellas Roman, Heidi, additional, Levine, Ross L., additional, Riva, Alberto, additional, Kopinke, Daniel, additional, Jobin, Christian, additional, Avram, Dorina, additional, and Guryanova, Olga A, additional

Published
2021
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42. Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3

Author

Guryanova, Olga A., Wu, Qiulian, Cheng, Lin, Lathia, Justin D., Huang, Zhi, Yang, Jinbo, MacSwords, Jennifer, Eyler, Christine E., McLendon, Roger E., Heddleston, John M., Shou, Weinian, Hambardzumyan, Dolores, Lee, Jeongwu, Hjelmeland, Anita B., Sloan, Andrew E., Bredel, Markus, Stark, George R., Rich, Jeremy N., and Bao, Shideng

Published
2011
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43. DNMT3A Harboring Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Author

Venugopal, Kartika, primary, Feng, Yang, additional, Nowialis, Pawel, additional, Xu, Huanzhou, additional, Shabashvili, Daniil E., additional, Berntsen, Cassandra M., additional, Kaur, Prabhjot, additional, Krajcik, Kathryn I., additional, Taragjini, Christina, additional, Zaroogian, Zachary, additional, Casellas Román, Heidi L., additional, Posada, Luisa M., additional, Gunaratne, Chamara, additional, Li, Jianping, additional, Dupéré-Richer, Daphné, additional, Bennett, Richard L., additional, Pondugula, Santhi, additional, Riva, Alberto, additional, Cogle, Christopher R., additional, Opavsky, Rene, additional, Law, Brian K., additional, Bhaduri-McIntosh, Sumita, additional, Kubicek, Stefan, additional, Staber, Philipp B., additional, Licht, Jonathan D., additional, Bird, Jonathan E., additional, and Guryanova, Olga A., additional

Published
2021
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44. Repurposing Tranexamic Acid as an Anticancer Agent

Author

Law, Mary E, primary, Davis, Bradley J, additional, Ghilardi, Amanda F, additional, Yaaghubi, Elham, additional, Dulloo, Zaafir M, additional, Wang, Mengxiong, additional, Guryanova, Olga, additional, Heldermon, Coy D, additional, Castellano, Ronald K, additional, and Law, Brian K, additional

Published
2021
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45. 3015 – CLONAL HEMATOPOIESIS DRIVEN BY PARTIAL DNMT3A LOSS CONTRIBUTES TO AN AGGRESSIVE PHENOTYPE OF COLITIS-ASSOCIATED COLON CANCER

Author

Guryanova, Olga A, primary, Feng, Yang, additional, Newsome, Rachel, additional, Robinson, Troy, additional, Bowman, Robert, additional, Zuniga, Ashley, additional, Hall, Kendra, additional, Berntsen, Cassandra, additional, Shabashvili, Daniil, additional, Levine, Ross, additional, Riva, Alberto, additional, Jobin, Christian, additional, and Avram, Dorina, additional

Published
2021
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46. NPM1mutation reprograms leukemic transcription network via reshaping TAD topology

Author

Lai, Qian, Hamamoto, Karina, Luo, Huacheng, Zaroogian, Zachary, Zhou, Caixian, Lesperance, Julia, Zha, Jie, Qiu, Yi, Guryanova, Olga A., Huang, Suming, and Xu, Bing

Abstract

C-terminal mutation of Nucleophosmin 1(NPM1C+) was thought to be a primary driving event in acute myeloid leukemia (AML) that reprograms leukemic-associated transcription programs to transform hematopoietic stem and progenitor cells (HSPCs). However, molecular mechanisms underlying NPM1C+-driven leukemogenesis remain elusive. Here, we report that NPM1C+activates signature HOX genes and reprograms cell cycle regulators by altering CTCF-driven topologically associated domains (TADs). Hematopoietic-specific NPM1C+knock-in alters TAD topology leading to disrupted regulation of the cell cycle as well as aberrant chromatin accessibility and homeotic gene expression, which results in myeloid differentiation block. Restoration of NPM1 within the nucleus re-establishes differentiation programs by reorganizing TADs critical for myeloid TFs and cell cycle regulators that switch the oncogenic MIZ1/MYC regulatory axis in favor of interacting with coactivator NPM1/p300, and prevents NPM1C+-driven leukemogenesis. In sum, our data reveal that NPM1C+reshapes CTCF-defined TAD topology to reprogram signature leukemic transcription programs required for cell cycle progression and leukemic transformation.

Published
2023
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47. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Author

Turcan, Sevin, Rohle, Daniel, Goenka, Anuj, Walsh, Logan A., Fang, Fang, Yilmaz, Emrullah, Campos, Carl, Fabius, Armida W.M., Lu, Chao, Ward, Patrick S., Thompson, Craig B., Kaufman, Andrew, Guryanova, Olga, Levine, Ross, Heguy, Adriana, Viale, Agnes, Morris, Luc G.T., Huse, Jason T., Mellinghoff, Ingo K., and Chan, Timothy A.

Subjects
Genomics -- Research, Methylation -- Research, Mutation (Biology) -- Research, Gliomas -- Genetic aspects -- Research, Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Both genome-wide genetic and epigenetic alterations are fundamentally important for the development of cancers, but the interdependence of these aberrations is poorly understood. Glioblastomas and other cancers with the CpG island methylator phenotype (CIMP) constitute a subset of tumours with extensive epigenomic aberrations and a distinct biology (1-3). Glioma CIMP (G-CIMP) is a powerful determinant of tumour pathogenicity, but the molecular basis of G-CIMP remains unresolved. Here we show that mutation of a single gene, isocitrate dehydrogenase 1 (IDH1), establishes G-CIMP by remodelling the methylome. This remodelling results in reorganization of the methylome and transcriptome. Examination of the epigenome of a large set of intermediate-grade gliomas demonstrates a distinct G-CIMP phenotype that is highly dependent on the presence of IDH mutation. Introduction of mutant IDH1 into primary human astrocytes alters specific histone marks, induces extensive DNA hypermethylation, and reshapes the methylome in a fashion that mirrors the changes observed in G-CIMP-positive lower-grade gliomas. Furthermore, the epigenomic alterations resulting from mutant IDH1 activate key gene expression programs, characterize G-CIMP- positive proneural glioblastomas but not other glioblastomas, and are predictive of improved survival. Our findings demonstrate that IDH mutation is the molecular basis of CIMP in gliomas, provide a framework for understanding oncogenesis in these gliomas, and highlight the interplay between genomic and epigenomic changes in human cancers., The isocitrate dehydrogenase genes IDH1 and IDH2 are mutated in >70% of lower-grade gliomas (grades II and III), in some glioblastomas (4,5), and in leukaemias and several other cancers (6,7). [...]

Published
2012
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