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OBJECTIVE: Diabetes in pregnancy is associated with several adverse outcomes for both mother and baby. Awareness is the first step toward identifying pregnant women with diabetes. The purpose of this study was to assess Turkish pregnant women's opinion and practice about 50-g glucose challenge test (GCT) and to assess the reasons why some of them refuse the test. METHODS: This study was conducted on 312 patients at any age and gestational week in Istanbul, Turkey, by a personal interview using self-created questionnaire. Women were asked about their opinion and practice about 50-g GCT. RESULTS: Among women who were =28 weeks of gestation, 42.5% (n=82/193) exhibited their desire to have a GCT in their ongoing pregnancy, 40.9% (n=79/193) pointed out their reluctance, and 16.6% (n=32/193) indicated that they had no opinion about the subject. Women who were =28 weeks of gestation and did not want to have GCT, were asked to explain the reasons of their reluctance. The most frequently indicated reason was the belief that GCT is harmful for their babies and themselves (n=62/79, 78.5%). Of the women who were >28 weeks of gestation, 37.8% (n=45/119) had GCT in the ongoing pregnancy, while 62.2% (n=74/119) did not have GCT. The most frequently indicated reason why women did not have a GCT was the belief that GCT is harmful for themselves and the baby (n=37/74, 50%). CONCLUSION: This study exposes an important problem - misinformation about 50-g GCT - that carries a dangerous potential for missing the diagnosis of gestational diabetes. Study findings put forth the need for raising awareness among pregnant women and training health-care professionals about the subject. [ABSTRACT FROM AUTHOR]

In this study, it is aimed to compare the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) and intraoperative frozen section in determining the depth of myometrial invasion in patients with endometrioid type endometrial cancer. Retrospective evaluation of 69 patients with endometrioid type endometrial cancer who underwent preoperative MRI and subsequently intraoperative frozen-section and surgical staging between February 2004 and September 2011. Surgical staging was performed according to 2009 FIGO classification. Final histopathological examination was accepted as the standard of reference. The median age of patients was 59 years (range 41-80 years). Histopathological evaluation revealed that 41 patients had superficial myometrial invasion (<50% of myometrium) and 28 had deep myometrial invasion (≥50% of myometrium). Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 64.2%, 87.8%, 78.2%, 78.2% and 78.2% for MRI, and 89.3%, 97.6 %, 96.2 %, 93.0 % and 94.2% for frozen-section, respectively. The diagnostic accuracy of the intraoperative frozen-section was significantly higher than that of preoperative MRI according to McNemar's test (p=0.03). A statistically significant negative correlation was found between MRI accuracy and tumor grade (p=0.0002). None of the other variables was associated with incorrect prediction of MRI. The rate of incorrect prediction of myometrial invasion with frozen-section was significantly higher in nonvisualized tumors (p=0.01). A significant difference was not detected with other variables and frozen-section. Intraoperative frozen section has a better accuracy compared to MRI in the assessment of myometrial invasion in endometrioid type endometrial cancer. MRI seems suboptimal in the identification of invasion to the myometrium. [ABSTRACT FROM AUTHOR]

Objective: Diabetes in pregnancy is associated with several adverse outcomes for both mother and baby. Awareness is the first step toward identifying pregnant women with diabetes. The purpose of this study was to assess Turkish pregnant women's opinion and practice about 50-g glucose challenge test (GCT) and to assess the reasons why some of them refuse the test., Methods: This study was conducted on 312 patients at any age and gestational week in Istanbul, Turkey, by a personal interview using self-created questionnaire. Women were asked about their opinion and practice about 50-g GCT., Results: Among women who were ≤28 weeks of gestation, 42.5% (n=82/193) exhibited their desire to have a GCT in their ongoing pregnancy, 40.9% (n=79/193) pointed out their reluctance, and 16.6% (n=32/193) indicated that they had no opinion about the subject. Women who were ≤28 weeks of gestation and did not want to have GCT, were asked to explain the reasons of their reluctance. The most frequently indicated reason was the belief that GCT is harmful for their babies and themselves (n=62/79, 78.5%). Of the women who were >28 weeks of gestation, 37.8% (n=45/119) had GCT in the ongoing pregnancy, while 62.2% (n=74/119) did not have GCT. The most frequently indicated reason why women did not have a GCT was the belief that GCT is harmful for themselves and the baby (n=37/74, 50%)., Conclusion: This study exposes an important problem - misinformation about 50-g GCT - that carries a dangerous potential for missing the diagnosis of gestational diabetes. Study findings put forth the need for raising awareness among pregnant women and training health-care professionals about the subject., Competing Interests: Conflict of Interest: The authors declare no conflict of interest.

Background: The aim of the present study was to compare the laparotomy (LT) and laparoscopy (LS) in patients who undergone surgical staging for early stage endometrium cancer., Methods: Retrospective data were collected and analyzed for amount of intraoperative bleeding, complication rates, total resected and laterality specific number of lymph nodes and duration of operation in patients operated with either LT or LS., Results: Seventy-nine stage I endometrium cancer patients were found to be eligible for the trial purposes: 58 (73.4%) treated by LT and 21 (26.6%) treated by LS. The number of lymph nodes was similar in LT (8.9 ± 5.3) and LS (9.2 ± 4.8) (P = 0.8). In LT group, there was no difference in the number of lymph nodes between the right and left sides (10 ± 5.8 and 8.7 ± 4.8 respectively, P = 0.19); in LS group, the number of lymph nodes resected from the right side was higher than the left side (9.8 ± 5 and 7 ± 3.5 respectively, P = 0.039). The amount of intraoperative bleeding and hospitalization period were significantly higher in LT group. Seventy-nine patients had a median follow-up of 30 months. The two groups were similar for disease-free survival (P = 0.46, log rank test)., Conclusions: There was no significant difference between the two methods in terms of number of total resected lymph nodes. In early stage endometrial carcinoma, LS has provided adequate staging and similar survival rates with LT.