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10 results on '"H.P. Brunner La Rocca"'

1. The Reply

Author

Roma Puronaite, H.P. Brunner-La Rocca, J. Simonavicius, Cardiologie, MUMC+: MA Med Staf Spec Cardiologie (9), and RS: Carim - H02 Cardiomyopathy

Subjects
Heart Failure, medicine.medical_specialty, business.industry, General Medicine, Disease, medicine.disease, Prognosis, Dermatology, Kidney transplant, EVENTS, Cellulitis, Chronic Disease, medicine, Humans, business, Problem Solving
Published
2019

2. P2‐500: PHYSICAL PERFORMANCE IN RELATION TO COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART‐BRAIN AXIS

Author

Astrid M. Hooghiemstra, Wiesje M. van der Flier, Hans-Peter H.P. Brunner-La Rocca, Albert C. van Rossum, Geert Jan Biessels, Robert J. van Oostenbrugge, Jaap Kappelle, Anna E. Leeuwis, and Leonie Franken

Subjects
Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Relation (database), Epidemiology, Physical performance, Health Policy, In patient, Neurology (clinical), Cognitive skill, Geriatrics and Gerontology, Psychology, Clinical psychology
Published
2018
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3. P2-392: COGNITIVE FUNCTIONING IN PATIENTS WITH DISORDERS ALONG THE HEART-BRAIN AXIS: THE ROLE OF CEREBRAL BLOOD FLOW

Author

Jacoba P. Greving, Geert Jan Biessels, Hans-Peter H.P. Brunner-La Rocca, Sanne Kuipers, Matthijs J P van Osch, Frederik Barkhof, Tugba Kalay, Eline A. Oudeman, Mark A. van Buchem, Jaap Kappelle, Robert J. van Oostenbrugge, Niels D. Prins, Wiro J. Niessen, Albert C. van Rossum, Esther E. Bron, Astrid M. Hooghiemstra, Wiesje M. van der Flier, and Anna E. Leeuwis

Subjects
medicine.medical_specialty, Epidemiology, business.industry, Health Policy, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Cerebral blood flow, Internal medicine, Cardiology, medicine, In patient, Neurology (clinical), Cognitive skill, Geriatrics and Gerontology, business
Published
2019
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4. [P1–486]: OCCURRENCE AND PROFILE OF COGNITIVE IMPAIRMENT IN PATIENTS WITH HEART FAILURE, CAROTID OCCLUSIVE DISEASE AND VASCULAR COGNITIVE IMPAIRMENT: THE HEART‐BRAIN CONNECTION STUDY

Author

Astrid M. Hooghiemstra, Annebet E. Leeuwis, Jaap Kappelle, Robert J. van Oostenbrugge, Anne Suzanne Bertens, Jacoba P. Greving, Michiel L. Bots, Wiesje M. van der Flier, Albert C. van Rossum, Hans-Peter H.P. Brunner-La Rocca, and Geert Jan Biessels

Subjects
medicine.medical_specialty, Epidemiology, Health Policy, Occlusive disease, medicine.disease, Connection (mathematics), Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Internal medicine, Heart failure, medicine, Physical therapy, Cardiology, In patient, Neurology (clinical), Geriatrics and Gerontology, Psychology, Cognitive impairment
Published
2017
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5. Discovery and validation of a new biomarker for heart failure diagnostic

Author

Michel Galinier, Philippe Rouet, François Koukoui, Jerome Roncalli, Jean Ferrières, Annie Turkieh, Pierre-Edouard Fournier, Luc W. Eurlings, Harald Mischak, Fatima Smih, H.P. Brunner La Rocca, Maria Francesca Evaristi, Franck Desmoulin, William Mullen, Mathieu Berry, Manon Barutaut, Roger Escamilla, Alain Cohen-Solal, C. Delmas, and Javed Butler

Subjects
Oncology, medicine.medical_specialty, business.industry, Cut off value, Rat model, Curve analysis, medicine.disease, Heart failure, Internal medicine, Cohort, medicine, Biomarker (medicine), Diagnostic biomarker, Cardiology and Cardiovascular Medicine, business
Abstract

Background Diagnostic biomarkers for heart failure (HF) such as the natriuretic peptides (NPs) are widely used but have limitations. Innovative biomarkers could provide improved diagnostic performance. Methods We launched a prospective case-control proteomic study and investigated for polypeptides specific to HF through a capillary electrophoresis-mass spectrometry (CE-MS) proteomic analysis. The putative biomarker was identified by Orbitrap liquid chromatography-MS, validated by western blot, then by ELISA using plasmas from multicentric international cohorts. A rat model of HF was tested for biomarker expression levels. Results We identified insulin like growth factor binding protein 2 (IGFBP2) as a new diagnostic biomarker for HF with a high sensitivity and specificity (AUC = 0.93; 95% CI, 0.89–0.96; P b 0.0001) in the local cohort and IGFBP2 levels provided an AUC of 0.943 (95% CI, 0.860–1.026) which gave a 87% sensitivity in AHF and 90% specificity at the cut off value previously determined in the discovery cohort, i.e. 556 ng/ml. ROC curve analysis of IGFBP2 and NTproBNP showed an AUC of 0.784 (95% CI, 0.744–0.820) for IGFBP2 and a significantly higher AUC of 0.927 (95% CI, 0.900–0.949) for NT-proBNP, P Conclusion IGFBP2 is a new biomarker to diagnose HF, which could be used to provide additional information to the NPs. Animals models, will help in the evaluation of the putative IGFBP2 regulated mechanisms in HF.

Published
2018
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8. Évaluation

Author

L. Haegeli, H.P. Brunner-La Rocca, M. Wenk, M. Pfisterer, J. Drewe, and S. Krähenbühl

Subjects
Pharmacology (medical)
Published
2008
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9. Incremental Cost-Effectiveness of Drug-Eluting Stents Compared With a Third-Generation Bare-Metal Stent in a Real-World Setting: Randomised Basel Stent Kosten Effektivitats Trial (BASKET)

Author

H.P. Brunner-La Rocca, P. Buser, and Christoph Kaiser

Subjects
Bare-metal stent, Marginal cost, medicine.medical_specialty, business.industry, medicine.medical_treatment, medicine, Stent, Cardiology and Cardiovascular Medicine, business, General Nursing, Third generation, Surgery
Published
2005
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10. [Heart failure in nursing home residents].

Author

Daamen MA, Hamers JP, Brunner-la Rocca HP, and Schols JM

Subjects
Aged, Aged, 80 and over, Chronic Disease epidemiology, Comorbidity, Cross-Sectional Studies, Diabetes Mellitus, Type 2 epidemiology, Dyspnea epidemiology, Female, Heart Failure diagnosis, Humans, Male, Medical Records, Prevalence, Pulmonary Disease, Chronic Obstructive epidemiology, Surveys and Questionnaires, Heart Failure epidemiology, Homes for the Aged statistics & numerical data, Nursing Homes statistics & numerical data
Abstract

Objective: To determine the prevalence of heart failure (HF) in nursing home residents and to gain insight into the clinical characteristics of residents with heart failure., Design: Multi-centre, observational, cross-sectional study., Method: 501 nursing home residents aged 65 years and over, in a department for chronic somatic diseases or a psychogeriatric department, participated in this study. The diagnosis of HF and the related characteristics were based on data collected from clinical examinations for heart failure (including history, physical examination, ECG, cardiac markers and echocardiography), patient records and questionnaires. A panel of two cardiologists and an internist-geriatrician made the final diagnosis of HF., Results: The prevalence of HF in nursing home residents was 33%. Dyspnoea, oedema and a history of cardiac disease were more common in residents with heart failure. Diabetes mellitus and chronic obstructive pulmonary disease also appeared to be more prevalent in this group. In 54% of the residents with HF, the diagnosis had not previously been made. Diagnosis of HF was not confirmed by the expert panel in 31% of residents with a history of HF., Conclusion: Heart failure does indeed appear to be very prevalent in nursing home residents. Heart failure had not been previously diagnosed in many cases but also a previous diagnosis of heart failure could be disproved in many participants. It is therefore important that the diagnostic process for heart failure in nursing home residents be improved.

Published
2016

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