1. End-stage renal disease - is infrainguinal limb revascularization justified?
- Author
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Harrington, Elizabeth B., Harrington, Martin E., Schanzer, Harry, and Haimov, Moshe
- Subjects
Peripheral vascular diseases -- Care and treatment ,Chronic kidney failure -- Complications ,Vascular grafts -- Health aspects ,Health - Abstract
There are few reports of vascular (blood vessels) reconstructive surgery performed to relieve arterial insufficiency in patients who have end-stage (terminal) kidney disease. These patients are believed to be poor risks for vascular surgery; many are diabetic and often have diffuse, severe arterial disease with calcification of the arteries. A study was undertaken of 39 patients with end-stage renal disease who underwent limb revascularization surgery to determine if the standard criteria for revascularization could be applied to this group of patients. Fifty-six legs underwent infrainguinal revascularization (bypass graft) surgery; nine legs had additional surgery for the removal of blood clots. Thirty-seven of the 39 patients were on dialysis, and 3 patients had functioning transplanted kidneys. Vascular surgery was performed because of ischemia (inadequate blood supply) resulting in gangrene (tissue death), leg pain at rest, leg ulcers, or severe claudication (leg cramping when walking). The rate of patency of the grafts at one year was 77 percent, and 68 percent at two years. During the follow-up period, which averaged 23 months (range 0 to 115 months), there were 24 deaths. Five deaths occurred in the perioperative period (shortly before to shortly after surgery), three of which were due to heart attack. At three years, 39 percent of the patients were alive with 84 percent of legs saved. These findings suggest that limb revascularization can be successfully performed on patients with end-stage renal disease, and that the standard criteria for revascularization surgery can be applied. (Consumer Summary produced by Reliance Medical Information, Inc.)
- Published
- 1990