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211 results on '"HANDALI, SUKWAN"'

1. The performance of a point-of-care test for the diagnosis of Neurocysticercosis in a resource-poor community setting in Zambia – a diagnostic accuracy study

Author

Zulu, Gideon, Stelzle, Dominik, Mwape, Kabemba E., Van Damme, Inge, Trevisan, Chiara, Mubanga, Chishimba, Schmidt, Veronika, Phiri, Isaac K., Mambo, Richard, Chembensofu, Mwelwa, Masuku, Maxwell, Ruether, Charlotte, Noh, John, Handali, Sukwan, Bottieau, Emmanuel, Magnussen, Pascal, Dorny, Pierre, Fleury, Agnes, Winkler, Andrea S., and Gabriël, Sarah

Published
2024
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2. Mass chemotherapy with niclosamide for the control of Taenia solium: population-based safety profile and treatment effectiveness

Author

Verastegui, Manuela R., Bustos, Javier A., Zimic, Mirko, Gonzales, Isidro, Saavedra, Herbert, Sanchez, Sofia S., Martinez, Manuel, Castillo, Yesenia, Toribio, Luz, Arroyo, Gianfranco, Orrego, Miguel A., Chile, Nancy, Mayta, Holger, Pajuelo, Monica, Santivañez, Saul, Gonzalez-Gustavson, Eloy, Gomez-Puerta, Luis, Gavidia, Cesar M., Vargas-Calla, Ana, Lopez, Maria T., Nash, Theodore E., Handali, Sukwan, Noh, John, Friedland, Jon, Wardle, Melissa T., Allen, Samantha E., Gamboa, Ricardo, Vilchez, Percy, O'Neal, Seth E., Muro, Claudio, Lescano, Andrés G., Moyano, Luz M., Gonzalvez, Guillermo E., González, Armando E., Gilman, Robert H., and García, Héctor H.

Published
2024
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3. Cross-Sectional Study of Soil-Transmitted Helminthiases in Black Belt Region of Alabama, USA

Author

Poole, Claudette, Barker, Troy, Bradbury, Richard, Capone, Drew, Chatham, Amy Hutson, Handali, Sukwan, Rodriguez, Eduardo, Qvarnstrom, Yvonne, and Brown, Joe

Subjects
Black Belt (Southern United States) -- Health aspects, Rural children -- Statistics -- Health aspects, Helminthiasis -- Statistics -- Risk factors -- Environmental aspects, Health
Abstract

Safe water and sanitation are fundamental to public health (1,2). Breakdowns in those systems lead to disease and, in temperate and tropical climates, soil-transmitted helminthiases (STH). STH are parasitic infections [...]

Published
2023
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4. Evaluation of a point-of-care test for the diagnosis of Taenia solium neurocysticercosis in rural southern Tanzania: a diagnostic accuracy study

Author

Chabala, Chishala, Mubanga, Chishimba, Jansen, Famke, Phiri, Isaac K., Mambo, Richard, Stelzle, Dominik, Makasi, Charles E, Schmidt, Veronika, Van Damme, Inge, Trevisan, Chiara, Ruether, Charlotte, Fleury, Agnès, Noh, John, Handali, Sukwan, Dorny, Pierre, Magnussen, Pascal, Zulu, Gideon, Mwape, Kabemba E, Bottieau, Emmanuel, Gabriël, Sarah, Ngowi, Bernard J, and Winkler, Andrea S

Published
2024
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5. Parasitic Disease Surveillance, Mississippi, USA

Author

Bradbury, Richard S., Lane, Meredith, Arguello, Irene, Handali, Sukwan, Cooley, Gretchen, Pilotte, Nils, Williams, John M., Jameson, Sam, Montgomery, Susan P., Hellmann, Kathryn, Tharp, Michelle, Haynie, Lisa, Galloway, Regina, Brackin, Bruce, Kirmse, Brian, Stempak, Lisa, Byers, Paul, Williams, Steven, Faruque, Fazlay, and Hobbs, Charlotte V.

Subjects
Mississippi -- Health aspects, Parasitic diseases -- Statistics -- Risk factors, Health
Abstract

Surveillance for soil-transmitted helminths, strongyloidiasis, cryptosporidiosis, and giardiasis was conducted in Mississippi, USA. PCR performed on 224 fecal samples for all soil-transmitted helminths and on 370 samples for only Necator [...]

Published
2021
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6. Deep humoral profiling coupled to interpretable machine learning unveils diagnostic markers and pathophysiology of schistosomiasis.

Author

Saha, Anushka, Chakraborty, Trirupa, Rahimikollu, Javad, Xiao, Hanxi, de Oliveira, Lorena B. Pereira, Hand, Timothy W., Handali, Sukwan, Secor, W. Evan, A. O. Fraga, Lucia, Fairley, Jessica K., Das, Jishnu, and Sarkar, Aniruddh

Subjects
FC receptors, ANTIBODY titer, PARASITIC diseases, MACHINE learning, SCHISTOSOMIASIS
Abstract

Schistosomiasis, a highly prevalent parasitic disease, affects more than 200 million people worldwide. Current diagnostics based on parasite egg detection in stool detect infection only at a late stage, and current antibody-based tests cannot distinguish past from current infection. Here, we developed and used a multiplexed antibody profiling platform to obtain a comprehensive repertoire of antihelminth humoral profiles including isotype, subclass, Fc receptor (FcR) binding, and glycosylation profiles of antigen-specific antibodies. Using Essential Regression (ER) and SLIDE, interpretable machine learning methods, we identified latent factors (context-specific groups) that move beyond biomarkers and provide insights into the pathophysiology of different stages of schistosome infection. By comparing profiles of infected and healthy individuals, we identified modules with unique humoral signatures of active disease, including hallmark signatures of parasitic infection such as elevated immunoglobulin G4 (IgG4). However, we also captured previously uncharacterized humoral responses including elevated FcR binding and specific antibody glycoforms in patients with active infection, helping distinguish them from those without active infection but with equivalent antibody titers. This signature was validated in an independent cohort. Our approach also uncovered two distinct endotypes, nonpatent infection and prior infection, in those who were not actively infected. Higher amounts of IgG1 and FcR1/FcR3A binding were also found to be likely protective of the transition from nonpatent to active infection. Overall, we unveiled markers for antibody-based diagnostics and latent factors underlying the pathogenesis of schistosome infection. Our results suggest that selective antigen targeting could be useful in early detection, thus controlling infection severity. Editor's summary: Schistosomiasis is a parasitic flatworm infection, and diagnosis is based on egg detection in stool. Current tests cannot distinguish between active and past infections. Saha and Chakraborty et al. developed a multiplexed antibody approach that used interpretable machine learning to distinguish different stages of disease. Comparing healthy and infected individuals across two human cohorts from Brazil and Kenya revealed previously uncharacterized signatures of active disease, including increased Fc receptor binding and specific antibody glycoforms. These signatures helped to separate individuals with active infection from those with past infection as well as to establish two distinct endotypes, those with low intensity or early infection and those with cleared prior infections, in those without active infection. These data suggest that profiling of humoral immune responses could be used to diagnose cases of schistosomiasis with higher precision. —Brandon Berry [ABSTRACT FROM AUTHOR]

Published
2024
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8. Lateral flow-based antibody testing for Chlamydia trachomatis

Author

Gwyn, Sarah, Mitchell, Alexandria, Dean, Deborah, Mkocha, Harran, Handali, Sukwan, and Martin, Diana L

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Infectious Diseases, Clinical Research, 4.1 Discovery and preclinical testing of markers and technologies, Detection, screening and diagnosis, Infection, Good Health and Well Being, Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Bacterial, Antigens, Bacterial, Bacterial Proteins, Child, Child, Preschool, Chlamydia Infections, Chlamydia trachomatis, Humans, Immunoassay, Infant, Middle Aged, Sensitivity and Specificity, Trachoma, Young Adult, Antibody, Serosurveillance, Lateral flow, Immunology
Abstract

We describe here a lateral flow-based assay (LFA) for the detection of antibodies against immunodominant antigen Pgp3 from Chlamydia trachomatis, the causative agent of urogenital chlamydia infection and ocular trachoma. Optimal signal detection was achieved when the gold-conjugate and test line contained Pgp3, creating a dual sandwich capture assay. The LFA yielded positive signals with serum and whole blood but not with eluted dried blood spots. For serum, the agreement of the LFA with the non-reference multiplex assay was 96%, the specificity using nonendemic pediatric sera was 100%, and the inter-rater agreement was κ=0.961. For whole blood, the agreement of LFA with multiplex was 81.5%, the specificity was 100%, and the inter-rater agreement was κ=0.940. The LFA was tested in a field environment and yielded similar results to those from laboratory-based testing. These data show the successful development of a lateral flow assay for detection of antibodies against Pgp3 with reliable use in field settings, which would make antibody-based testing for trachoma surveillance highly practical, especially after cessation of trachoma elimination programs.

Published
2016

12. Evaluation of a point-of-care test for the diagnosis of Taenia solium neurocysticercosis in rural southern Tanzania: a diagnostic accuracy study

Author

Stelzle, Dominik, primary, Makasi, Charles E, additional, Schmidt, Veronika, additional, Van Damme, Inge, additional, Trevisan, Chiara, additional, Ruether, Charlotte, additional, Fleury, Agnès, additional, Noh, John, additional, Handali, Sukwan, additional, Dorny, Pierre, additional, Magnussen, Pascal, additional, Zulu, Gideon, additional, Mwape, Kabemba E, additional, Bottieau, Emmanuel, additional, Gabriël, Sarah, additional, Ngowi, Bernard J, additional, Winkler, Andrea S, additional, Chabala, Chishala, additional, Mubanga, Chishimba, additional, Jansen, Famke, additional, Phiri, Isaac K., additional, and Mambo, Richard, additional

Published
2023
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16. Low sensitivity and frequent cross‐reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis

Author

Garcia, Hector H., Castillo, Yesenia, Gonzales, Isidro, Bustos, Javier A., Saavedra, Herbert, Jacob, Louis, Del Brutto, Oscar H., Wilkins, Patricia P., Gonzalez, Armando E., Gilman, Robert H., Tsang, Victor C.W., Rodriguez, Silvia, Martinez, Manuel, Alvarado, Manuel, Porras, Miguel, Vargas, Victor, Ccjuno, Alfredo, Verastegui, Manuela, Zimic, Mirko, Mayta, Holger, Guerra, Cristina, Castro, Yagahira, Lopez, Maria T., Gavidia, Cesar M., Gomez, Luis, Moyano, Luz M., Gamboa, Ricardo, Muro, Claudio, Vilchez, Percy, Nash, Theodore E., Mahanty, Siddhartha, Noh, John, Handali, Sukwan, and Friedland, Jon

Published
2018
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17. Baylisascaris procyonis roundworm seroprevalence among , United States and Canada, 2012-2015

Author

Sapp, Sarah G.H., Rascoe, Lisa N., Wilkins, Patricia P., Handali, Sukwan, Gray, Elizabeth B., Eberhard, Mark, Woodhall, Dana M., Montgomery, Susan P., Bailey, Karen L., Lankau, Emily W., and Yabsley, Michael J.

Subjects
Zoonoses -- Care and treatment -- Risk factors, Baylisascaris -- Research, Health
Abstract

Bhylisascaris procyonis, a roundworm of raccoons (Procyon lotor) and rarely dogs, can cause fatal neural larva migrans or ocular larval migrans in numerous bird and mammal species, including humans (1). [...]

Published
2016
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20. Improved diagnosis of viable parenchymal neurocysticercosis by combining antibody banding patterns on enzyme-linked immunoelectrotransfer blot (EITB) with antigen ELISA assay

Author

Arroyo Hurtado, Gianfranco, Bustos Palomino, Javier Arturo, Lescano Guevara, Andres Guillermo, Gonzales, Isidro, Saavedra Pastor, Herbert, Pretell, E. Javier, Castillo Berrios, Yesenia, Perez, Erika, Handali, Sukwan, Noh, John, Dorny, Pierre, Gilman, Robert Hugh, O'Neal, Seth E., Gonzalez Zariquiey, Armando Emiliano, and García Lescano, Héctor Hugo

Subjects
urogenital system, Taenia solium, EITB banding patterns, Ag-ELISA, Viable NCC
Abstract

The diagnosis of neurocysticercosis (NCC) depends on neuroimaging and serological confirmation. While antibody detection by enzyme-linked immunoelectrotransfer blot (EITB) fails to predict viable NCC, EITB banding patterns provide information about the host's infection course. Adding antigen enzyme-linked immunosorbent assay (Ag-ELISA) results to EITB banding patterns may improve their ability to predict or rule out of viable NCC. We assessed whether combining EITB banding patterns with Ag-ELISA improves discrimination of viable infection in imaging-confirmed parenchymal NCC. EITB banding patterns were grouped into classes using latent class analysis. True-positive and false-negative Ag-ELISA results in each class were compared using Fisher's exact test. Four classes were identified: 1, EITB negative or positive to GP50 alone (GP50 antigen family); 2, positive to GP42-39 and GP24 (T24/42 family), with or without GP50; and 3 and 4, positive to GP50, GP42-39, and GP24 and reacting to bands in the 8-kDa family. Most cases in classes 3 and 4 had viable NCC (82% and 88%, respectively) compared to classes 2 and 1 (53% and 5%, respectively). Adding positive Ag-ELISA results to class 2 predicted all viable NCC cases (22/22 [100%]), whereas 11/40 patients (27.5%) Ag-ELISA negative had viable NCC (P < 0.001). Only 1/4 patients (25%) Ag-ELISA positive in class 1 had viable NCC, whereas 1/36 patients (2.8%) Ag-ELISA negative had viable NCC (P = 0.192). In classes 3 and 4, adding Ag-ELISA was not contributory. Combining Ag-ELISA with EITB banding patterns improves discrimination of viable from nonviable NCC, particularly for class 2 responses. Together, these complement neuroimaging more appropriately for the diagnosis of viable NCC.

Published
2022

21. Seroprevalence of Baylisascaris procyonis infection among humans, Santa Barbara County, California, USA, 2014-2016

Author

Weinstein, Sara B., Lake, Camille M., Chastain, Holly M., Fisk, David, Handali, Sukwan, Kahn, Philip L., Montgomery, Susan P., Wilkins, Patricia P., Kuris, Armand M., and Lafferty, Kevin D.

Subjects
Baylisascaris -- Risk factors -- Research, Health
Abstract

The raccoon roundworm (Baylisascaris procyonis) is a potential health risk to humans. Infected raccoons release eggs in their feces, and these eggs accumulate at communal defecation sites (latrines). When nonraccoon [...]

Published
2017
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23. Evaluation of an Antibody Detecting Point of Care Test for Diagnosis of Taenia solium Cysticercosis in a Zambian Rural Community: A Prospective Diagnostic Accuracy Study

Author

Mubanga, Chishimba, primary, Van Damme, Inge, additional, Trevisan, Chiara, additional, Schmidt, Veronika, additional, Phiri, Isaac K., additional, Zulu, Gideon, additional, Noh, John, additional, Handali, Sukwan, additional, Mambo, Richard, additional, Chembensofu, Mwelwa, additional, Masuku, Maxwell, additional, Reynders, Dries, additional, Jansen, Famke, additional, Bottieau, Emmanuel, additional, Magnussen, Pascal, additional, Winkler, Andrea S., additional, Dorny, Pierre, additional, Mwape, Kabemba E., additional, and Gabriël, Sarah, additional

Published
2021
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24. Challenges Encountered When Evaluating an Antibody-Detecting Point-of-Care Test for Taeniosis in an Endemic Community in Zambia: A Prospective Diagnostic Accuracy Study

Author

Mubanga, Chishimba, primary, Trevisan, Chiara, additional, Van Damme, Inge, additional, Schmidt, Veronika, additional, Phiri, Isaac K., additional, Zulu, Gideon, additional, Noh, John, additional, Handali, Sukwan, additional, Mambo, Richard, additional, Chembensofu, Mwelwa, additional, Masuku, Maxwell, additional, Reynders, Dries, additional, Jansen, Famke, additional, Bottieau, Emmanuel, additional, Magnussen, Pascal, additional, Winkler, Andrea S., additional, Dorny, Pierre, additional, Mwape, Kabemba E., additional, and Gabriel, Sarah, additional

Published
2021
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26. Development of a Multiplex Bead Assay To Detect Immunoglobulin G Antibodies to Babesia duncani in Human Serum

Author

Wang, Yong, primary, Aderohunmu, TaLesa, additional, Bishop, Henry, additional, McAuliffe, Isabel, additional, Rivera, Hilda N., additional, Smith, Darlyne, additional, Wilkins, Patricia P., additional, Bowden, Katherine E., additional, Reed, Matthew S., additional, Svoboda, Pavel, additional, Stuchlik, Olga, additional, Pohl, Jan, additional, Wiegand, Ryan E., additional, and Handali, Sukwan, additional

Published
2021
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27. Neurocysticercosis. A frequent cause of seizures, epilepsy, and other neurological morbidity in most of the world

Author

Bustos Palomino, Javier Arturo, Gonzales, Isidro, Saavedra Pastor, Herbert, Handali, Sukwan, García Lescano, Héctor Hugo, and Cysticercosis Working Group in Peru

Subjects
retina, treatment planning, seizure, albendazole, disease classification, serology, Neurocysticercosis, antiparasitic agent, Article, mental disease, subarachnoid space, computer assisted tomography, cognitive defect, neurologist, Taenia solium, human, nuclear magnetic resonance imaging, Tropical neurology, Epilepsy, neuroimaging, nonhuman, parasite clearance, Cysticercosis, Research Diagnostic Criteria, disease course, praziquantel, spinal cord, infection control, neurologic disease, clinical feature, disease severity assessment, intracranial hypertension, prognosis, human activities, antiinflammatory agent, headache
Abstract

Neurocysticercosis is endemic in most of the world and in endemic areas it accounts for approximately 30% of cases of epilepsy. Appropriate diagnosis and management of neurocysticercosis requires understanding the diverse presentations of the disease since these will vary in regards to clinical manifestation, sensitivity of diagnostic tests, and most importantly, therapeutic approach. This review attempts to familiarize tropical neurology practitioners with the diverse types of neurocysticercosis and the more appropriate management approaches for each

Published
2021

28. Evaluation of an antibody detecting point of care test for diagnosis of Taenia solium cysticercosis in a Zambian rural community:A prospective diagnostic accuracy study

Author

Mubanga, Chishimba, Van Damme, Inge, Trevisan, Chiara, Schmidt, Veronika, Phiri, Isaac K, Zulu, Gideon, Noh, John, Handali, Sukwan, Mambo, Richard, Chembensofu, Mwelwa, Masuku, Maxwell, Reynders, Dries, Jansen, Famke, Bottieau, Emmanuel, Magnussen, Pascal, Winkler, Andrea S, Dorny, Pierre, Mwape, Kabemba E, Gabriël, Sarah, Mubanga, Chishimba, Van Damme, Inge, Trevisan, Chiara, Schmidt, Veronika, Phiri, Isaac K, Zulu, Gideon, Noh, John, Handali, Sukwan, Mambo, Richard, Chembensofu, Mwelwa, Masuku, Maxwell, Reynders, Dries, Jansen, Famke, Bottieau, Emmanuel, Magnussen, Pascal, Winkler, Andrea S, Dorny, Pierre, Mwape, Kabemba E, and Gabriël, Sarah

Abstract

The lack of cheap, easy-to-use, rapid diagnostic tests has led to the development of several rapid diagnostic tests for cysticercosis. The new prototype two-strip, Taenia solium point of care test (TS POC) detects antibodies against taeniosis (TS POC T) and cysticercosis (TS POC CC). This study evaluated the diagnostic performance of the TS POC CC in the Sinda district in eastern Zambia. A sample of 1254 participants was recruited and tested with the TS POC. Out of the 1249 participants with a valid TS POC result, 177 (14%) tested positive while 1072 (86%) tested negative. All individuals with a positive TS POC and a subset of negative TS POC participants were selected for serum sampling, and were subjected to the recombinant glycoprotein T24H enzyme-linked immunoelectrotransfer blot (rT24H EITB) and the serum B60/158 (serum Ag) enzyme-linked immunosorbent assay (Ag ELISA). Performance characteristics were estimated using a Bayesian approach with probabilistic constraints. Based on 255 complete cases, the estimated sensitivity and specificity of the TS POC CC test were 35% (95% CI: 14-63%) and 87% (95% CI: 83-90%), respectively. The diagnostic performance needs to be improved, possibly by titrating antigen and other reagents' concentration in the strip to produce a performance similar to existing cysticercosis tests such as the rT24H EITB.

Published
2021

29. Challenges encountered when evaluating an antibody-detecting point-of-care test for Taeniosis in an endemic community in Zambia:A prospective diagnostic accuracy study

Author

Mubanga, Chishimba, Trevisan, Chiara, Van Damme, Inge, Schmidt, Veronika, Phiri, Isaac K, Zulu, Gideon, Noh, John, Handali, Sukwan, Mambo, Richard, Chembensofu, Mwelwa, Masuku, Maxwell, Reynders, Dries, Jansen, Famke, Bottieau, Emmanuel, Magnussen, Pascal, Winkler, Andrea S, Dorny, Pierre, Mwape, Kabemba E, Gabriel, Sarah, Mubanga, Chishimba, Trevisan, Chiara, Van Damme, Inge, Schmidt, Veronika, Phiri, Isaac K, Zulu, Gideon, Noh, John, Handali, Sukwan, Mambo, Richard, Chembensofu, Mwelwa, Masuku, Maxwell, Reynders, Dries, Jansen, Famke, Bottieau, Emmanuel, Magnussen, Pascal, Winkler, Andrea S, Dorny, Pierre, Mwape, Kabemba E, and Gabriel, Sarah

Abstract

Taenia solium taeniosis diagnosis is challenging because current tests perform sub-optimally and/or are expensive, require sophisticated equipment, infrastructure and trained manpower, and therefore are not community deployable. A recently-developed, multi-strip, T. solium point-of-care test (TS POC) for simultaneous detection of tapeworm (TS POC T) and cysticercus (TS POC CC) human antibodies was evaluated for diagnostic accuracy on consecutively recruited community participants in Sinda district, Zambia. All participants were tested using the TS POC test. All test-positives and 20% of the test-negative participants were invited to give a blood and stool sample for reference testing. Three different reference tests were used for taeniosis diagnosis: recombinant rES33 enzyme-linked immunoelectrotransfer blot (rES33 EITB), copro PCR and copro Ag ELISA. Bayesian analysis with probabilistic constraints was used to estimate sensitivity and specificity. In total, 1254 participants were tested with the TS POC test, of whom 13 tested positive using the TS POC T. Based on 161 participants with complete data, the estimated sensitivity and specificity for the TS POC T test were 38% (95% CI: 5-93%) and 99% (95% CI: 98-100%), respectively. The challenge of highly variable inter-assay performance is highlighted. We recommend either increasing the sensitivity or redesigning the test.

Published
2021

32. Mass chemotherapy with niclosamide for the control of Taenia solium: population-based safety profile and treatment effectiveness

Author

Wardle, Melissa T., Allen, Samantha E., Gamboa, Ricardo, Vilchez, Percy, O'Neal, Seth E., Muro, Claudio, Lescano, Andrés G., Moyano, Luz M., Gonzalvez, Guillermo E., González, Armando E., Gilman, Robert H., García, Héctor H., Verastegui, Manuela R., Bustos, Javier A., Zimic, Mirko, Gonzales, Isidro, Saavedra, Herbert, Sanchez, Sofia S., Martinez, Manuel, Castillo, Yesenia, Toribio, Luz, Arroyo, Gianfranco, Orrego, Miguel A., Chile, Nancy, Mayta, Holger, Pajuelo, Monica, Santivañez, Saul, Gonzalez-Gustavson, Eloy, Gomez-Puerta, Luis, Gavidia, Cesar M., Vargas-Calla, Ana, Lopez, Maria T., Nash, Theodore E., Handali, Sukwan, Noh, John, and Friedland, Jon

Abstract

Mass drug administration (MDA) with niclosamide (NSM) can be used to control taeniasis, the cause of neurocysticercosis. NSM is 84.3% effective against taeniasis and is considered safe as it is not absorbed from the intestinal tract. However, information on its safety and effectiveness during MDA is limited. We evaluated the effectiveness of NSM and reported adverse events (AEs) during a cysticercosis elimination program in Tumbes, Peru.

Published
2024
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34. Parasitic Infection Surveillance in Mississippi Delta Children

Author

Bradbury, Richard S., primary, Arguello, Irene, additional, Lane, Meredith, additional, Cooley, Gretchen, additional, Handali, Sukwan, additional, Dimitrova, Silvia D., additional, Nascimento, Fernanda S., additional, Jameson, Sam, additional, Hellmann, Kathryn, additional, Tharp, Michelle, additional, Byers, Paul, additional, Montgomery, Susan P., additional, Haynie, Lisa, additional, Kirmse, Brian, additional, Pilotte, Nils, additional, Williams, Steven A., additional, and Hobbs, Charlotte V., additional

Published
2020
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35. Surveillance for Soil Transmitted Helminths, Strongyloidiasis, Toxocariasis, Cryptosporidiosis and Other Parasitic Diseases in Mississippi

Author

Bradbury, Richard S., primary, Lane, Meredith, additional, Arguello, Irene, additional, Handali, Sukwan, additional, Cooley, Gretchen, additional, Pilotte, Nils, additional, Williams, John M., additional, Jameson, Sam, additional, Montgomery, Susan P., additional, Hellman, Kathryn, additional, Tharp, Michelle, additional, Haynie, Lisa, additional, Galloway, Regina, additional, Brackin, Bruce, additional, Kirmse, Brian M., additional, Stempak, Lisa, additional, Byers, Paul, additional, Williams, Steven, additional, Faruque, Fazlay, additional, and Hobbs, Charlotte Victoria, additional

Published
2020
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36. Human Seroprevalence to 11 Zoonotic Pathogens in the U.S. Arctic, Alaska

Author

Miernyk, Karen M., primary, Bruden, Dana, additional, Parkinson, Alan J., additional, Hurlburt, Debby, additional, Klejka, Joseph, additional, Berner, James, additional, Stoddard, Robyn A., additional, Handali, Sukwan, additional, Wilkins, Patricia P., additional, Kersh, Gilbert J., additional, Fitzpatrick, Kelly, additional, Drebot, Mike A., additional, Priest, Jeffrey W., additional, Pappert, Ryan, additional, Petersen, Jeannine M., additional, Teshale, Eyasu, additional, Hennessy, Thomas W., additional, and Bruce, Michael G., additional

Published
2019
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38. Acute Muscular Sarcocystosis: An International Investigation Among Ill Travelers Returning From Tioman Island, Malaysia, 2011-2012

Author

Esposito, Douglas H., Stich, August, Epelboin, Loïc, Malvy, Denis, Han, Pauline V., Bottieau, Emmanuel, da Silva, Alexandre, Zanger, Philipp, Slesak, Günther, van Genderen, Perry J. J., Rosenthal, Benjamin M., Cramer, Jakob P., Visser, Leo G., Muñoz, José, Drew, Clifton P., Goldsmith, Cynthia S., Steiner, Florian, Wagner, Noémie, Grobusch, Martin P., Plier, D. Adam, Tappe, Dennis, Sotir, Mark J., Brown, Clive, Brunette, Gary W., Fayer, Ronald, von Sonnenburg, Frank, Neumayr, Andreas, Kozarsky, Phyllis E., Van Den Enden, Erwin, Van Esbroeck, Marjan, Ghesquiere, Wayne, Nguyen, Duc, Receveur, Marie-Catherine, Peyron, François, Parola, Philippe, Savini, Hélène, Caumes, Eric, Perignon, Alice, Develoux, Michel, Rapp, Christophe, Keller, Christian A., Haditsch, Martin, Güthoff, Wolfgang, Liebold, Ines, Schäfer, Johannes, Gobbi, Federico, Kortmann, Willemijn, van Twillert, Gitte, Goorhuis, Abraham, Harris, Vanessa, van Vugt, Michèle, Stijnis, Kees, Aronica, Eleonora, van Lieshout, Lisette, Roestenberg, Meta, van Wout, Jan, Barkham, Timothy, Lim, Poh Lian, Chian, Lee Kong, Hatz, Christoph, Brugger, Silvio D., Furrer, Hansjakob, Chappuis, François, Michel, Yann, Choochumporn, Sanya, Narkwiboonwong, Than, Dryden, Matthew S., Benedict, Theresa, Handali, Sukwan, Wilkins, Patricia P., Shieh, Wun-Ju, Zaki, Sherif, Kogelman, Laura, and Hatch, Steven

Subjects
musculoskeletal diseases, parasitic diseases, virus diseases, human activities, geographic locations
Abstract

A large outbreak of acute muscular sarcocystosis (AMS) among international tourists who visited Tioman Island, Malaysia, is described. Clinicians evaluating travelers returning ill from Malaysia with myalgia, with or without fever, should consider AMS in their differential diagnosis

Published
2017

44. Evaluating the Recombinant T24H Enzyme-Linked Immunoelectrotransfer Blot Assay for the Diagnosis of Neurocysticercosis in a Panel of Samples from a Large Community-Based Randomized Control Trial in 60 Villages in Burkina Faso

Author

Dermauw, Veronique, primary, Carabin, Hélène, additional, Cissé, Assana, additional, Millogo, Athanase, additional, Tarnagda, Zékiba, additional, Ganaba, Rasmané, additional, Noh, John, additional, Handali, Sukwan, additional, Breen, Kathleen, additional, Richter, Vivian, additional, Cissé, Rabiou, additional, Preux, Pierre-Marie, additional, Boncoeur-Martel, Marie-Paule, additional, Winkler, Andrea Sylvia, additional, Van Hul, Anke, additional, Dorny, Pierre, additional, and Gabriël, Sarah, additional

Published
2018
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46. Identifying wildlife reservoirs of neglected taeniid tapeworms: Non-invasive diagnosis of endemic Taenia serialis infection in a wild primate population

Author

Schneider-Crease, India, primary, Griffin, Randi H., additional, Gomery, Megan A., additional, Dorny, Pierre, additional, Noh, John C., additional, Handali, Sukwan, additional, Chastain, Holly M., additional, Wilkins, Patricia P., additional, Nunn, Charles L., additional, Snyder-Mackler, Noah, additional, Beehner, Jacinta C., additional, and Bergman, Thore J., additional

Published
2017
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49. Feasibility of a point-of-care test based on quantum dots with a mobile phone reader for detection of antibody responses.

Author

Lee, Chan, Noh, John, O’Neal, Seth E., Gonzalez, Armando E., Garcia, Hector H., null, null, and Handali, Sukwan

Subjects
QUANTUM dots, ANTIBODY formation, CELL phones, POINT-of-care testing, TAENIA solium
Abstract

We developed a novel and portable fluorescent sensor that integrates a lateral flow assay with a quantum dot (Qdots) label and a mobile phone reader for detection of specific antibodies in human serum. We evaluated the utility of this assay to test for antibodies to the Taenia solium rT24H antigen. It was a retrospective study by examining 112 positive human sera from patients with neurocysticercosis (NCC) including samples from patients with single viable cyst (n = 18), two or more viable cysts (n = 71), and subarachnoid (racemose) cysts (n = 23). These samples were collected from previous study subjects in Lima, Peru that conducted under an approved study protocol in Peru. The sera were made anonymous under a protocol approved by the CDC Institutional Review Board. Definitive diagnosis of the specimen was established by computed-tomography and/or magnetic resonance imaging. To test the specificity of the assay, we evaluated a panel of serum samples obtained from patients with other infections (n = 24), and serum samples from persons in the United States and Egypt who had not traveled outside their country, and therefore are presumed negative for cysticercosis (n = 128). The assay specificity in the negative panel was 99% (95–100%) while assay sensitivity was 89% (79–95%) in NCC patients with two or more viable cysts. Our assay has performance characteristics similar to those of traditional platforms for the detection of NCC and shows promise as a mobile phone reader-based point-of-care test for antibody detection. [ABSTRACT FROM AUTHOR]

Published
2019
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50. Baylisascaris procyonisRoundworm Seroprevalence among Wildlife Rehabilitators, United States and Canada, 2012–2015

Author

Sapp, Sarah G.H., primary, Rascoe, Lisa N., additional, Wilkins, Patricia P., additional, Handali, Sukwan, additional, Gray, Elizabeth B., additional, Eberhard, Mark, additional, Woodhall, Dana M., additional, Montgomery, Susan P., additional, Bailey, Karen L., additional, Lankau, Emily W., additional, and Yabsley, Michael J., additional

Published
2016
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