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2. NOACs for coronary or peripheral artery disease: a systematic review and meta-analysis of mortality and major bleeding

Author

Nagy, Ádám, Kim, Jun H, Jeong, Myeong E, Heo, Min H, Putzu, Alessandro, Belletti, Alessandro, Biondi-Zoccai, Giuseppe, Landoni, Giovanni, Nagy, Ádám, Kim, Jun H, Jeong, Myeong E, Heo, Min H, Putzu, Alessandro, Belletti, Alessandro, Biondi-Zoccai, Giuseppe, and Landoni, Giovanni

Abstract

Several high quality randomized controlled studies were recently published on non-vitamin K oral anticoagulants (NOACs) in patients with or at risk for coronary artery (CAD) or peripheral artery disease (PAD). While a reduction on cardiovascular event is known and an increase in moderate bleeding is expected, the effect of this strategy on survival is currently unknown. Accordingly, we performed a comprehensive systematic review and meta-analysis of randomized controlled trials to investigate the effect of NOAC on survival.

Published
2019

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