33 results on '"HERKİLOĞLU, Dilşad"'
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2. Uropathogens According to the Trimesters, and Their Effects on Pregnancy Outcomes: A Retrospective Clinical Study
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GÖKÇE, Şefik, primary, HERKİLOĞLU, Dilşad, additional, BAYIRLI TURAN, Derya, additional, KİLİSLİ, Nazmiye Nil, additional, DEMİRBİLEK, Osman, additional, and ONUK, Özkan, additional
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- 2024
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3. Depression and Anxiety Disorders in Patients with Hyperemesis Gravidarum and the Effect of This Disease on the Quality of Life
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HERKİLOĞLU, Dilşad, primary and GÖKÇE, Şefik, additional
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- 2022
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4. Positive Effect of Transobturator Tape Procedure on Female Sexual Function: Analytical Research
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GÖKÇE, Şefik, primary, HERKİLOĞLU, Dilşad, additional, and ONUK, Özkan, additional
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- 2022
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5. Impact of knowledge, attitude and anxiety levels about COVID-19 on the quality of life in pregnant women
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GÖKÇE, Şefik, primary and HERKİLOĞLU, Dilşad, additional
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- 2021
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6. Cardiovascular risk factors in polycystic ovary syndrome; the relationship of dyslipidemia and obesity
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GÖKÇE, Şefik, primary and HERKİLOĞLU, Dilşad, additional
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- 2021
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7. Depression and Anxiety Disorders in Patients with Hyperemesis Gravidarum and the Effect of This Disease on the Quality of Life
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HERKİLOĞLU, Dilşad and GÖKÇE, Şefik
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Health Care Sciences and Services ,Hyperemesis gravidarum,Beck Anxiety Inventory,Beck Depression Inventory ,Sağlık Bilimleri ve Hizmetleri ,Hiperemezis gravidarum,Beck Anksiyete Envanteri,Beck Depresyon Envanteri - Abstract
Amaç: Hiperemezis gravidarum, hamile kadınlarda ciddi komplikasyonlardan daha sık depresyon veya anksiyete bozukluğuna yol açabilir. Bu durum hamile kadının yaşam kalitesini önemli ölçüde bozabilir. Çalışmamızda hiperemezis gravidarum hastalarında depresyon ve anksiyete düzeylerinin araştırılması ve hiperemezisin yaşam kalitesine etkisinin incelenmesi amaçlanmıştır.Gereç ve Yöntemler: Çalışmaya 01.04.2018-01.10.2018 tarihleri arasında hastanemize başvuran 87 hiperemezis tanısı almış, 24 hiperemezisli hasta dahil edildi. Tüm katılımcılar Beck Anksiyete Envanteri, Beck Depresyon Envanteri ve 12 soruluk yaşam kalitesi (SF-12) formlarını aldı.Bulgular: Çalışmaya dahil edilen hastaların ortalama yaşı 25,4 ± 5,0 yıl (Yaş aralığı: 17-39) idi. Tüm katılımcılarda minimal minimal anksiyete ve depresyon tespit edildi. Hiperemezis tanısı alan hasta grubu ile kontrol grubu arasında ortalama depresyon puanı (p = 0.161) ve anksiyete puanı (p = 0.266) açısından anlamlı bir fark yoktu. Gruplar arasında depresyon ve anksiyete düzeylerinin dağılımı açısından anlamlı fark bulunmadı (sırasıyla p = 0,46 ve p = 0,557).Sonuç: Sonuç olarak bulgularımız, anksiyete ve depresyon düzeylerinin hiperemezis gravidarum ile doğrudan ilişkili olamayacağını göstermektedir. Ancak hiperemezis tanısı almış gebelerin psikolojik durumlarının yakından izlenmesi, gerekli destek tedavilerinin yapılması ve yaşam kalitelerinin iyileştirilmesi gerekmektedir., Background: Hyperemesis gravidarum can lead to depression or anxiety disorder in pregnant women more frequently than serious complications. This situation can significantly deteriorate the quality of life of the pregnant woman. In our study, it was aimed to investigate the levels of depression and anxiety in patients with hyperemesis gravidarum, and to analyze the effect of hyperemesis on quality of life.Materials and Methods: The study included 87 patients diagnosed with hyperemesis and 24 patients without hyperemesis admitted to our hospital between the dates of 01.04.2018-01.10.2018. All participants received Beck Anxiety Inventory, Beck Depression Inventory and 12-question quality of life (SF-12) forms.Results: The mean age of the patients included in the study was 25.4±5.0 years (Age range: 17-39 years). Minimal minimal anxiety and depression were detected in all participants. There was no significant difference between the group of patients diagnosed with hyperemesis and the control group in terms of mean depression score (p=0.161) and anxiety score (p=0.266). No significant difference was found in terms of the distribution of depression and anxiety levels between the groups (p=0.46 and p=0.557, respectively). Conclusion: In conclusion, our findings show that anxiety and depression levels cannot be directly correlated with hyperemesis gravidarum. However, it is necessary to closely monitor the psychological status of pregnant women diagnosed with hyperemesis, to perform the necessary supportive treatments and to improve their quality of life.
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- 2020
8. A New Questionnaire for Aesthetic Gynecology: A Self-appraisal Questionnaire for Female Genital Cosmetic Procedure Demand (Q-FGCP).
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Herkiloğlu, Dilşad, Şahin, Sadık, Kabaca, Canan, Önal, Cansu, Hazine, Burak, and Eroğlu, Mustafa
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PLASTIC surgery , *SEXUAL excitement - Abstract
Objective: Today, demand for genital cosmetic procedures is increasing among women. However, despite the rapid increase in popularity of these procedures, research questionnaires to determine whether there is a real need for genital aesthetic procedures for patients are still limited. The objective of this study is to develop a self-assessment questionnaire for female genital cosmetic procedures, to use this questionnaire for genital appearance satisfaction within the general population and to evaluate the correlation between total item score and demand. Methods: The questionnaire was conducted on 100 women who were thought to reflect the general population who presented to the Gynecology and Obstetrics clinics of our tertiary hospital. The questionnaire, which consisted of 11 items, was prepared to screen the women who needed cosmetic genital procedures. The first 10 items included factor analysis regarding aesthetic appearance of the genital organs (items 1-8) and its impact on sexual pleasure (items 9 and 10). Item 11 questioned how much participants needed a cosmetic gynecologic procedure. Results: A strong need for genital aesthetic procedures was observed in 41% of the participants. When demographic variables were analyzed in terms of the desire for cosmetic procedures; only the first 10 questions were statistically significantly related to the total score. It was shown that a total score >19 was an important factor for women desiring to undergo genital cosmetic procedures (odds ratio: 3.9, confidence interval: 1.7-9.2, p=0.011). Conclusion: This scoring system will be helpful in determining whether there is a real need for genital aesthetic procedures in the general population, and whether patients with an actual need for genital aesthetic procedures can be directed with this scoring since perception of women with regards to vaginal cosmetic procedures can differ from that of professionals. [ABSTRACT FROM AUTHOR]
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- 2022
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9. Relationship of Endometrial Polyp Prediction with Clinical and Demographic Findings
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Herkiloğlu, Dilşad, primary, Gökçe, Şefik, additional, Göksedef, Pınar, additional, Kabaca, Canan, additional, and Sağıroğlu, Gülhan, additional
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- 2020
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10. TUBAL GEÇİRGENLİK DEĞERLENDİRİLMESİNDE HİSTEROSALPİNGOGRAFİ Mİ? LAPAROSKOPİ Mİ? : İNFERTİL OLGULARIN RETROSPEKTİF ANALİZİ
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HERKİLOĞLU, Dilşad, primary and GÖKÇE, Şefik, additional
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- 2020
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11. Transobturator Bant Prosedürünün Kadın Cinsel Fonksiyonu Üzerine Olumlu Etkisi: Analitik Araştırma.
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GÖKÇE, Şefik, HERKİLOĞLU, Dilşad, and ONUK, Özkan
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Copyright of Journal of Reconstructive Urology is the property of Turkiye Klinikleri and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2022
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12. THE EFFECTS OF PLATELET RICH PLASMA (PRP) AND GROWTH HORMONE (GWH) TREATMENTS ON TELOMERASE ACTIVITY AND TELOMERE LENGTH IN PATIENTS WITH DIMINISHED OVARIAN RESERVE
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Herkiloglu, Dilsad, Arican, Ercan, Gokce, Sefik, Yuceturk, Aysen, Cevik, Ozge, Tiras, Bulent, and Cakiroglu, Yigit
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- 2022
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13. Belief levels in sexual myths in women and effects of myths on sexual satisfaction
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Gökce, Şefik, primary and Herkiloğlu, Dilşad, additional
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- 2020
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14. HİDROSALPİNKS TANISINDA ULTRASONOGRAFİ VE HİSTEROSALPİNGOGRAFİ YETERİNCE GÜVENİLİR Mİ?
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HERKİLOĞLU, Dilşad and KABACA, Canan
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animal structures ,Health Care Sciences and Services ,Hidrosalpinks,İnfertilte ,Hydrosalpinx,Infertility ,Sağlık Bilimleri ve Hizmetleri - Abstract
HİDROSALPİNKS TANISINDAULTRASONOGRAFİ VE HİSTEROSALPİNGOGRAFİ YETERİNCE GÜVENİLİR Mİ? ÖZET AMAÇ:İnfertilhastaların uterin boşluğu ve fallop tüplerini ilk basamak değerlendirme ultrasonografi(USG) ile olup bir sonraki aşamada diğer gelişmiş ve etkili yöntemler olmasınarağmen histerosalpingografi (HSG) ucuz, kolaylıkla erişilebilir ve yorumlanmasıkolay olduğundan yaygın olarak kullanılmaktadır. Çalışmamızda HSG ve USGsonucunda hidrosalpinks ön tanısı konulan hastaların laparoskopi ilekorelasyonunu değerlendirerek HSG’nin ve USG’nin hidrosalpinks tanısı koymadakideğeri ve birbirlerine üstünlüğü olup olmadığını göstermeyi amaçladık.YÖNTEM:Çalışmaya1 Ağustos 2015 ile 1 Nisan 2017 tarihleri arasında hastanemizin kadın doğumpolikliniklerine infertilite nedeniyle ile başvuran HSG’de ya da USG’dehidrosalpinks saptanan 48 hasta dahil edildi. Tüm hastalar genel anestezialtında, laparoskopi ile opere edildi. Laparoskopide her iki tuba serbest metilen mavisi geçişi değerlendirildi. HSGveya USG sonucu ile laparoskopi sonucunun korele olmaması HSG’nin ya da USG’ninyanlış teşhisi olarak değerlendirildi. Laparoskopide patolojik bulguların olması halinde HSG ya da USG teşhisidoğru olarak kabul edildi. BULGULAR:48hastanın 30’u primer infertil 18’i sekonder infertildi. 26 hastaya HSG ilehidrosalpinks düşünüldü. Laparoskopi sonrası 15’inde (%57,7) hidrosalpinksdoğrulandı. 25 hastaya USG ile hidrosalpinks ön tanısıyla laparoskopi yapıldı.17’sinde (%68) hidrosalpinks doğrulandı.3 hastada hem USG de hemde HSG de hidrosalpinks mevcuttu. Bu hastalarda USGbulgularının laparoskopi ile korelasyonu değerlendirildi. Hsg’nin teşhisdoğruluğu (%57,7) USG’nin teşhis doğruluğu (%68) ile arasında istatistiksel birfark saptanmadı. (P=0,638). SONUÇ: İnfertiliteninilk basamak değerlendirmelerinden olan USG ve HSG ile ucuz ve kolay bir şekildehidrosalpinks tanısı konulabilir. Anahtarsözcükler: Hidrosalpinks, İnfertilte, Laparoskopi, ULTRASONOGRAPHY ANDHYSTEROSALPHYNOGRAPHY RELIABLE IN THE DIAGNOSIS OF HYDROSALPİNX?SUMMARYOBJECTIVE: Although the first stepevaluation of infertile patients with uterine cavity and fallopian tubes isultrasonography (USG), hysterosalpingography (HSG) is widely used because it ischeap, easily accessible and easy to interpret, although other advanced and effectivemethods are available at the next stage. In our study, we aimed to evaluate thecorrelation of HSG and USG with laparoscopy of patients with hydrosalpinx presumptivediagnosis and to show whether HSG and USG are superior to each other inhyphrosalpinx diagnosis.METHODS: Between August 1, 2015 andApril 1, 2017, 48 patients who were admitted to our obstetric gynecology out patientclinic for infertility, or who underwent hydrosalpinx in USG were included inthe study. All patients underwent laparoscopy under general anesthesia.Laparoscopy was used to evaluate the incidence of free methylene blue in bothtuba. Correlation of HSG or USG result with laparoscopy result was assessed asfalse diagnosis of HSG or USG. In the case of pathological findings onlaparoscopy, HSG or USG diagnosis was accepted correctly.RESULTS: Of the 48 patients, 30 were primerinfertile 18 were secondary to infertile. 26 patients were considered hydrosalpinxwith HSG. Hydrosalpinx was confirmed in 15 (57.7%) of the patients after laparoscopy.Twenty-five patients underwent laparoscopy with USG and hydrosalpinx anterior diagnosis.In 17 (68%) hydrosalpinx was confirmed. In 3 patients, both USG and HSG hadhydrosalpinx. The correlation of USG findings with laparoscopy was evaluated inthese patients. There was no statistically significant difference between the diagnosticaccuracy of HSG (57.7%) and the diagnostic accuracy of USG (68%). (P = 0.638).CONCLUSION: USG and HSG, which are thefirst-line evaluations of infertility, can diagnose hydrosalpinx cheaply and easily.
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- 2018
15. Endometrial Polip Öngörüsünün Klinik ve Demografik Bulgular ile İlişkisi.
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Herkiloğlu, Dilşad, Gökçe, Şefik, Göksedef, Pınar, Kabaca, Canan, and Sağıroğlu, Gülhan
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Objective: Endometrial polyp (EP) can be diagnosed clinically by transvaginal ultrasonography (TVUSG). In our study, we aimed to show the effectiveness of TVUSG in detecting EP with the hysteroscopy (H/S) results of patients who applied to our clinic and were considered for EP in TVUSG. Methods: One hundred twenty-five patients who were admitted to the obstetrics outpatient clinics of our hospital between August 1, 2015 and April 1, 2017 and were scheduled for H/S operation with a pre-diagnosis of EP were included in the study. The relationship between the age, abnormal uterine bleeding (AUB), infertility history, and the presence of EP after H/S was examined in the patients who had EP appearance on ultrasonography. The H/S results of patients with suspected EP in TVUSG and the efficiency of TVUSG in detecting EP were investigated. Results: The average age of the patients was 38.04±8.47 and ranged from 21 to 63. A significant difference was found in H/S between the ages of those with polyps and those without them (p=0.012). In patients with polyps in H/S, the average endometrium thickness was 13.36±5.37 mm, and in non-polyps, endometrium thickness was 14.08±4.58 mm. There was no significant difference in terms of endometrial thickness (p=0.141). The rate of AUB history (34.5%) in those with polyps seen in H/S was significantly higher than the rate of AUB history (13.2%) in those without polyps (p=0.007). Polyps were observed in H/S in 76% of 73 cases aged >35, and this rate was found to be significantly higher than cases under 35 years old. The sensitivity and negative predictive value was the highest in the diagnosis of polyp in the case of >35 years old alone (64.3% and 76.7%, respectively); Specificity and positive predictive value were the highest in both AUB and >35 years of age (89.4% and 85.7%, respectively). Conclusion: With TVUSG, the diagnosis of EP can be made with high accuracy in the presence of over 35 years of age with AUB findings. [ABSTRACT FROM AUTHOR]
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- 2020
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16. IN WOMEN WHO APPLY FOR POSTMENOPAUSAL BLEEDING, IS ENDOMETRIAL CYTOLOGY SUFFICIENT TO DIAGNOSE ?
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HERKİLOĞLU, Dilşad, primary, EROĞLU, Mustafa, additional, ŞAHİN, Sadik, additional, and TAYYAR, Ahter, additional
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- 2018
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17. The role of T cells and some cytokins in endometrial tissue in unexplained infertility
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Çıracı, Enver, Şahin, Sadık, Değirmencioğlu, Sevgin, Herkiloğlu, Dilşad, M. Tekin, Babaç, Ünal, Tuna, Tetik, Şermin, and Biruni Üniversitesi
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24th Biennial International Congress on Thrombosis / EMLTD Congress -- MAY 04-07, 2016 -- Istanbul, TURKEY
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- 2016
18. Endometrial mrna expressions of cytokines in women with in vitro fertilization failure
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Sahin, Sadık, Herkiloğlu, Dilşad, Ciraci, E., Değirmencioğlu, Sevgin, Ünal, Tayfun, Uras, Fikriye, Tetik, Şermin, and Biruni Üniversitesi
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24th Biennial International Congress on Thrombosis / EMLTD Congress -- MAY 04-07, 2016 -- Istanbul, TURKEY
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- 2016
19. Which factors are associated with the recurrence of endometrioma after cystectomy?
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Küçükbaş, Mehmet, primary, Kurek Eken, Meryem, additional, İlhan, Gülşah, additional, Şenol, Taylan, additional, Herkiloğlu, Dilşad, additional, and Kapudere, Bilge, additional
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- 2017
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20. OVERİN GRANÜLOZA HÜCRELİ TÜMÖRLERİNDE ENDOMETRİAL BULGULARIN DEĞERLENDİRİLMESİ
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EKEN, Meryem, KAYGUSUZ, Ecmel, ŞAHİN ERSOY, Gülçin, ÇÖĞENDEZ, Ebru, HERKİLOĞLU, Dilşad, and KARATEKE, Ateş
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Health Care Sciences and Services ,Granüloza hücreli tümör,Endometrial bulgular,Over ,Granulosa cell tumors,Endometrial findings,Ovary ,Sağlık Bilimleri ve Hizmetleri - Abstract
Introduction : Characterized by tendency for delayed recurrences and good prognosis mostly, granulosa cell tumors represent the most common sex-cord stromal tumors of the ovary and form 2-3% of all ovarian cancers. Clinically, they are well-known for their potent estrogenic capacity and postmenopausal bleeding constitutes its most common clinical sign, which usually ensues following the prolonged exposure of the endometrium to estrogen released from the tumor. Therefore, estrogen-related endometrial anomalies are frequently encountered in patients with granulosa cell tumors. In this study we aimed to present the patients with granulosa cell tumors operated in our institution and to evaluate their endometrial findings in the light of a literature review. Material and methods: Endometrial findings of the patients who had been operated in the Obstetrics and Gynecology Department of Zeynep Kamil Training and Research Hospital were retrospectively analyzed. The pathological specimens belonging to the individual cases were re-evaluated and changes in the endometrium were noted. Endometrial findings were classified as endometrial cancer, endometrial hyperplasia (complex with/without atypia, simple with/without atypia), endometrial polyp, irregular proliferative endometrial layer and non-significant findings. Results: The analysis of 29 endometrial specimens has revealed endometrial polyp in 8 cases, irregular proliferative endometrium in 3 patients, endometrial hyperplasia in 7 cases and endometrioid adenocarcinoma in one patient. Among the patients diagnosed with endometrial hyperplasia 2 patients had complex endometrial hyperplasia with atypia, one had complex endometrial hyperplasia without atypia and 4 patients had simple endometrial hyperplasia without atypia. Neither the tumor differentiation grades nor the tumor diameters have demonstrated a correlation with the endometrial findings. Conclusion: Granulosa cell tumors are hormonally active, therefore they can give rise to endometrial pathologies leading to secondary symptoms and findings. Therefore when an adnexial mass is detected and a granulosa cell tumor is suspected, the evaluation of the patient should be extended for all endometrial pathologies, Amaç: Geç nüks eğilimli ve çoğunlukla iyi prognozlu olan granüloza hücreli tümörler overin en sık görülen sex-cord stromal tümörleridir. Tüm over kanserlerinin ise %2-3’ünü oluştururlar. Klinikte en çok östrojenik etki gösteren over tümörü olarak bilinirler ve endometriyumun tümörden salınan östrojene uzun süre maruz kalması nedeniyle ortaya çıkan postmenopozal kanama en sık izlenen klinik bulgusudur. Bu nedenle granüloza hücreli tümörlü hastalarda östrojen ilişkili endometriyal anormallikler sıklıkla beklenir. Çalışmamızda hastanemizde opere olan granüloza hücreli tümör vakalarının literatür ışığında endometrial bulgularını tartışmayı amaçladık. Gereç ve yöntemler: Zeynep Kamil Eğitim ve Araştırma Hastanesi’nde opere olan hastaların endometrial bulguları retrospektif olarak incelendi. Olguların patoloji arşivindeki materyalleri tekrar gözden geçirildi ve endometriumda izlenen değişiklikler not edildi. Endometriumdaki bulgular endometriyal kanser, endometrial hiperplazi (kompleks,atipili, atipisiz ve basit, atipili, atipisiz), endometriyal polip, düzensiz proliferatif endometrium varlığı ve özellik izlenmeyen olarak gruplandırıldı. Bulgular: Yirmidokuz olgunun endometriumlarında; 8 olguda endometriyal polip, 3 olguda düzensiz proliferatif endometrium, 7 olguda endometrial hiperplazi ve 1 olguda endometrioid adenokarsinom saptandı. Endometrial hiperplazi saptanan hastalardan 2’sinde kompleks atipili endometriyal hiperplazi, 1’inde kompleks atipisiz endometrial hiperplazi, 4’ünde de basit atipisiz endometrial hiperplazi mevcuttu. Tümörlerin diferansiyasyon dereceleri ile endometrium bulguları arasında bir ilişki saptanmadı. Tümör çapları ile endometrium bulguları arasında bir ilişki söz konusu değildi. Sonuç: Granüloza hücreli tümörler hormon olarak aktif olmaları sebebiyle endometrial patolojilere sebep olarak sekonder bulgu ve semptomlara yol açmaktadırlar. Bu sebeple adneksiyel patoloji saptanıp granüloza hücreli tümör düşünülen olgularda endometrial patolojiler iyi değerlendirilmelidir.
- Published
- 2015
21. UTERİN KARSİNOSARKOMLAR: 18 OLGUDA HİSTOPATOLOJİK GÖZDEN GEÇİRME
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KAYGUSUZ, Ecmel, EKEN, Meryem, HERKİLOĞLU, Dilşad, ÇÖĞENDEZ, Ebru, and KARATEKE, Ateş
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Health Care Sciences and Services ,Sağlık Bilimleri ve Hizmetleri ,Carcinosarcoma,Uterus,Malign mixed Müllerian tumor ,Karsinosarkom,Uterus,Malign mikst Müllerian tümör - Abstract
Objective: Uterine carcinosarcomas are relatively rare tumors with poor prognosis. These tumors were considered as a subset of uterine sarcomas; however currently they are classified within the carcinoma group. Recent studies have revealed that these tumors behave according to the characteristics of the epithelial component. The aim of the study was to discuss the histopathological characteristics of these quite aggressive tumors, which were diagnosed in our clinic, in the light of the literature. Materials and Methods: We performed a retrospective analysis of 18 patients with uterine sarcoma, who were operated at our oncology department between 2004 and 2014. Cases with a pathology result of either carcinosarcoma or malignant mixed Müllerian tumor were included in the study pathologically. Tumor size, presence of myometrial invasion and pelvic lymph node metastases were reviewed. Demographic data were recorded. Staging was performed according to FIGO (1988) protocol. Results: 18 patients were diagnosed with carcinosarcoma. 95% of the patients were in postmenopausal period. The mean age was 64.6 . 13 patients underwent comprehensive surgical staging (total hysterectomy + bilateral salpingo-oophorectomy + pelvic para-aortic lymphadenectomy + omentectomy + appendectomy). 5 patients with advanced stage disease underwent suboptimal debulking. 7 patients were stage I and 11 patients were stage II-IV. Myometriyal invasion was present in 17 patients and for 9 of these patients the invasion was observed in more than ½ of the myometrium. Lymphovascular invasion was observed in 11 patients. Conclusion: Uterine carcinosarcomas are extremely aggressive neoplasms. Although they used to be categorized under the group of sarcoma, recent studies have shown that uterine carcinosarcomas are high-grade endometrial carcinomas, which include sarcomatous metaplasia. First-line treatment for uterine carcinosarcomas is surgery. Adjuvant chemotherapy and radiation therapy combinations are used as complementary therapies, Amaç: Uterin karsinosarkomlar nadir görülen oldukça kötü prognozlu tümörlerdir. Daha önceleri uterin sarkomların bir alt grubu olarak değerlendirilen bu tümörler artık karsinom grubu içinde değerlendirilmektedir. Yeni yapılan çalışmalarda bu tümörlerin klinik davranışının epitelyal komponentin özelliklerine bağlı olduğu belirtilmektedir.Çalışmamızda kliniğimizde tanı alan ve oldukça agresif davranışlı olan bu tümorleri literatür ışığında histopatolojik özellikleriyle tartışmayı amaçladık.Gereç ve Yöntemler: Hastanemiz obstetrik ve onkoloji bölümünde 2004-2014 yılları arasında opere edilen uterin karsinosarkom olguları retrospektif olarak incelendi. Bölümümüzde karsinosarkom veya malign mikst Müllerian tümör tanısı alan olgular çalışmaya dahil edildi. Tümör boyutları, myometriyal invazyon varlığı, pelvik lenf nodu metastazları gözden geçirildi. Demografik veriler kayıt edildi. Evreleme FIGO (1988) protokolüne göre yapıldı.Sonuçlar: Hastanemizde karsinosarkom tanısı alan 18 hastanın %95 i postmenopozal dönemde olup ortalama yaş 64,6 (47-85) olarak izlendi. 13 hastaya evreleme cerrahisi (total histerektomi+ bilateral salpingooferektomi+ pelvik paraaortik lenfadenektomi+omentektomi+appendektomi) 5 olguya ise ileri evrede olması sebebiyle suboptimal debulking yapıldı. 7 olgumuz evre-I iken, 11 olgumuz evre II-IV idi. Myometriyal invazyon17 hastada mevcutken, bunların 9 tanesinde invazyon myometriyumun ½’den fazlasını tutmuş görünümdeydi. Lenfovasküler invazyon 11 hastada izlendi.Tartışma ve Sonuç: Uterin karsinosarkomlar oldukça agresif neoplazmalardır. Önceden sarkomlar grubunda incelenirlerken, son çalışmalar uterin karsinosarkomların sarkomatöz metaplazi içeren yüksek dereceli endometriyal karsinomlar olduklarını göstermiştir. Tedavide ilk seçenek cerrahi olup, adjuvan kemoterapi ve radyoterapi kombinasyonları tamamlayıcı tedavi olarak kullanılmaktadır.
- Published
- 2014
22. Assessment of maternal and perinatal outcomes in pregnant women with isolated proteinuria
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Kuyucu, Melda, primary, Arınkan, Sevcan Arzu, additional, Herkiloğlu, Dilşad, additional, and Muhcu, Murat, additional
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- 2016
- Full Text
- View/download PDF
23. The impact of abdominal and laparoscopic hysterectomies on women’s sexuality and psychological condition
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Kürek Eken, Meryem, primary, İlhan, Gülşah, additional, Temizkan, Osman, additional, Erbek Çelik, Evrim, additional, Herkiloğlu, Dilşad, additional, and Karateke, Ateş, additional
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- 2016
- Full Text
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24. ATYPICAL STROMAL CELLS IN AN ENDOMETRIAL POLYP: A CASE REPORT
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Kaygusuz, Ecmel Işık, EKEN, Meryem, ŞAHİN, Gülçin Ersoy, HERKİLOĞLU, Dilşad, and KARATEKE, Ateş
- Subjects
Stromal cells,Uterine diseases,Polyps ,Stromal hücreler,Uterus Hastalıkları,Polipler - Abstract
Literatürde, kadın genital sisteminde atipik stromal hücreler özellikle vagina, vulva ve serviksi içeren alt genital sistemde başlıca da fibroepitelyal polipler üzerinde tanımlanmışlardır. Polipler endometrium epiteli ile örtülü olup değişik oranlarda gland stroma ve kan damarlarından oluşurlar. Sıklıkla kabul edilen görüş endometrial poliplerin kanser öncüsü olduğudur. Klinik olarak premenopozal dönemde menometroraji postmenopozal dönemde ise anormal uterin kanama ile semptom verirler. Atipik hücreler özellikle endometriyumda oldukça nadir olarak rapor edilmişlerdir. Bu hücreler özellikle küçük endometriyal örneklerde malign hücreler ile karışabilir (adenosarkom, endometrial stromal sarkom ve karsinosarkom). Radikal cerrahiyi önlemek için, patologların ve jinekologların kadın genital sistemindeki bu atipik hücrelerin farkında olması gerekmektedir., Atypical stromal cells of the female genital tract have been already described in the literature, which are predominantly observed as a feature of fibroepithelial polyps of the lower genital system including vagina, vulva and cervix. Polyps are covered with endometrial lining and composed of varying amounts of glandular stroma and blood vessels. Endometrial polyps are usually regarded as a cancer precursor. Clinically patients with endometrial polyps apply to a hospital with menometrorrhagia in the premenopausal period and abnormal uterine bleeding in the postmenopausal period. However these atypical cells have been rarely encountered in the endometrium. Following limited endometrial sampling these cells are frequently confused with malignant cells (adenosarcoma, endometrial stromal sarcoma and carcinosarcoma). In order to prevent radical surgery, the pathologist as well as the gynecologist need to know these atypical cells of the female genital system very well.
- Published
- 2013
25. Which factors are associated with the recurrence of endometrioma after cystectomy?
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Küçükbaş, Mehmet, Kurek Eken, Meryem, İlhan, Gülşah, Şenol, Taylan, Herkiloğlu, Dilşad, and Kapudere, Bilge
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ENDOMETRIOSIS ,CYSTECTOMY ,LAPAROSCOPIC surgery ,FERTILITY preservation ,PREOPERATIVE care ,PATIENTS ,TISSUE adhesions ,DYSMENORRHEA ,LAPAROSCOPY ,PELVIC pain ,PROGNOSIS ,TUMOR antigens ,DISEASE relapse ,TREATMENT effectiveness ,RETROSPECTIVE studies - Abstract
Endometrioma is the most common form of endometriosis and is a sign of wide-spread disease in symptomatic patients. Medical treatment options can be successful in endometrioma smaller than 1 cm, but ineffective for growing and symptomatic endometriomas. Conservative surgical interventions that preserve fertility, such as laparoscopic removal or destruction of endometriotic tissue or aspiration of cystic content are typically used to treat the condition. One of the most frustrating aspects of endometrioma treatment is disease recurrence. The underlying mechanisms explaining recurrence are uncertain. Several risk factors have been evaluated in order to predict recurrence after cystectomy. In looking at the results overall, our study can conclude that the presence of greater cyst dimension, higher CA-125 level, presence of preoperative symptoms of non-cyclic pelvic pain, dysmenorrhoea and adhesion extension may be associated with recurrent endometrioma. In clinical practice, identification of risk factors for recurrence helps clinicians to inform patients. Impact statement What is already known on this subject: Endometrioma is the most common form of endometriosis and is a sign of wide-spread disease in symptomatic patients. One of the most frustrating aspects of endometrioma treatment is disease recurrence. Several risk factors have been evaluated in order to predict recurrence after cystectomy. However, the risk factors have not been precisely defined. What the results of this study add: This study aimed to investigate the contribution of possible risk factors to the recurrence of endometrioma after laparoscopic surgery. In looking at the results overall, our study can conclude that the presence of greater cyst dimension, higher CA-125 level, adhesion extension, presence of preoperative symptoms of non-cyclic pelvic pain and dysmenorrhoea may be associated with recurrent endometrioma. What the implications of these findings are for clinical practice and/or further research: In clinical practice, identification of risk factors for recurrence helps clinicians to inform patients. Detection of preoperative risk factors would be helpful in counselling patients on their future prognosis. This may also increase treatment success by providing accurate preoperative treatment planning and by assisting the scheduling of postoperative follow-ups. [ABSTRACT FROM AUTHOR]
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- 2018
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26. HOLOPROSENSEFALİ: ALTI OLGUDA İLİŞKİLİ MALFORMASYONLAR VE KLİNİK BULGULAR
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KAYGUSUZ, Ecmel Işık, primary, EKEN, Meryem, additional, HERKİLOĞLU, Dilşad, additional, İÇÖZ, Şeyma, additional, and KARATEKE, Ateş, additional
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- 2015
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27. Primary carcinoma of the fallopian tubes: Analysis of sixteen patients
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Eken, Meryem, primary, Temizkan, Osman, additional, Kaygusuz, Ecmel Işık, additional, Herkiloğlu, Dilşad, additional, Çöğendez, Ebru, additional, and Karateke, Ateş, additional
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- 2015
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28. UTERİN KARSİNOSARKOMLAR: 18 OLGUDA HİSTOPATOLOJİK GÖZDEN GEÇİRME
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KAYGUSUZ, Ecmel Işık, primary, EKEN, Meryem, additional, HERKİLOĞLU, Dilşad, additional, ÇÖĞENDEZ, Ebru, additional, and KARATEKE, Ateş, additional
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- 2015
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29. Prolapsus of Cervical Leiomyoma After Vaginal Delivery: Case Report
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ÇÖĞENDEZ, Ebru, primary, ANĞIN, Ali Doğukan, additional, EKEN, Meryem, additional, POLAT, Mesut, additional, HERKİLOĞLU, Dilşad, additional, and KARATEKE, Ateş, additional
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- 2015
- Full Text
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30. The impact of abdominal and laparoscopic hysterectomies on women's sexuality and psychological condition.
- Author
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Eken, Meryem Kürek, İlhan, Gülşah, Temizkan, Osman, Çelik, Evrim Erbek, Herkiloğlu, Dilşad, and Karateke, Ateş
- Abstract
Copyright of Turkish Journal of Obstetrics & Gynecology is the property of Galenos Yayinevi Tic. LTD. STI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
- Full Text
- View/download PDF
31. İzole proteinürili gebelerde maternal ve perinatal sonuçların değerlendirilmesi.
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Kuyucu, Melda, Arınkan, Sevcan Arzu, Herkiloğlu, Dilşad, and Muhcu, Murat
- Abstract
Copyright of Perinatal Journal / Perinatoloji Dergisi is the property of Deomed Publishing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
- Full Text
- View/download PDF
32. Accuracy of power Doppler ultrasonography for detecting intrauterine focal lesions: a correlation with doppler ultrasound and hysteroscopic hystopathology.
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Çöğendez', Ebru, Eken, Meryem, Temizkan, Osman, Kaygusuz, EcmcI Işık, Herkiloğlu, Dilşad, Eroğlu, Mustafa, and Muhçu, Murat
- Subjects
DOPPLER ultrasonography ,INTRAUTERINE contraceptives ,HYSTEROSCOPY - Abstract
Objective: To compare power Doppler flow mapping characteristics of endometrial polyps and submucosal fibroids and analyze whether different power Doppler characteristics can help to differentiate these focal endometrial lesions. Methods: Fifty-eight women (median age, 37 years; range, 25-51 years) presenting with abnormal uterine bleeding and infertility on transvaginal ultrasund suggested focal endometrial lesions underwent sonohysterography were included in this prospective study. Three different vascular patterns were defined: Pattern A: single-vessel pattern, Pattern B: rim-like vessel pattern C: multiple vessel pattern. These were compared with the final histopathological diagnosis. Results: Histological diagnoses were as follows: Endometrial polyp 40 (69%), submucousal myoma 18 (31%). Power Doppler signals were observed in 53 of these; they were not observed in five patients with endometrial polyps. We find out 75% pattern A, 2.5% pattern B and 7.5% pattern C in vascularized polyps, and also submucous myomas we find out 5.6% pattern A, 66.7% pattern B and 27.8% pattern C. The sensitivity, specificity and positive and negative predictive values for single vessel pattern in diagnosing endometrial polyps were 80, 100, 100, and 69.23%; for multiple vessels pattern in diagnosing submucousal myomas were 27.78, 92.5, 62.5 and 74%; for rim-like vessel pattern in diagnosing submucosal fibroids, they were 72.22, 100, 100 and 88.9%, respectively. Conclusion: Power Doppler blood flow mapping is reasonable in the diagnosis of intrauterine focal lesions and is practical in distinguishing endometrial polyps and submucosal fibroids. [ABSTRACT FROM AUTHOR]
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- 2014
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33. The impact of abdominal and laparoscopic hysterectomies on women's sexuality and psychological condition.
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Kürek Eken M, İlhan G, Temizkan O, Çelik EE, Herkiloğlu D, and Karateke A
- Abstract
Objective: To investigate whether there were any differences in the quality of life, sexual function, and self-esteem of patients who underwent total laparoscopic hysterectomy (TLH) (n=42) and total abdominal hysterectomy (TAH) (n=42)., Materials and Methods: All premenopausal patients who underwent TLH or TAH because of benign uterine disorders were enrolled. The sexual function and quality of life status were assessed preoperatively and 6 months postoperatively using three standardized validated questionnaires: the Arizona Sexual Experiences Scale (ASEX), the Symptom Checklist-90-Revised (SCL-90-R), and the Rosenberg Self-Esteem Scale (RSES)., Results: Preoperative ASEX, SCL-90-R and RSES scores were not different among the hysterectomy subgroups. The postoperative SCL-90-R scores were also not different among the hysterectomy subgroups. The postoperative RSES scores were significantly lower (p<0.05) than the preoperative scores for all procedures (indicating improved self-esteem) but did not differ among the groups. The postoperative ASEX scores were significantly decreased (p<0.01) as compared with the preoperative scores (indicating improved sexual function). When the average score of each item of the ASEX score was compared in both groups, significant differences were observed in sexual drive and arousal in the laparoscopy group (p<0.01)., Conclusion: Women undergoing TLH for benign uterine disease may have better outcomes related to certain sexual function parameters than women undergoing TAH., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors.
- Published
- 2016
- Full Text
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