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One of the most fulminant and quickly spreading types of fungal infection, mucormycosis typically starts in the nose and paranasal sinuses after inhaling spores. Orbital and intracranial structures may become infected either directly or through blood vessels, leading to life-threatening complications. This infection most commonly manifests in the rhinomaxillary area, particularly in individuals with immunocompromised conditions like diabetes. Even with appropriate treatment, the disease's mortality rate can exceed 40%, and it is challenging to detect. The standard treatment plan involves surgical debridement combined with systemically active antifungal medications, depending on the site of infection and risk factors. As a first-line treatment, lipid-based amphotericin B is recommended; however, posaconazole also shows promise. Hereby, the authors present a case report of a 15-year-old male patient with juvenile diabetes mellitus who had been experiencing pain and diffuse swelling in his left malar area for the previous two months. Following a histological analysis and clinical and radiographic evaluation by a multidisciplinary team, the patient was diagnosed with maxillary mucormycosis. Because of the abundant blood supply in the maxillofacial regions; however, more virulent fungi like Mucor can get past this obstacle. The purpose of present article is to show how early detection and treatment of mucormycosis in a young patient could prevent major morbidity and mortality from this potentially fatal illness. Additionally, it aimed to contribute to the local epidemiology of mucormycosis and raise awareness among stakeholders attention to the difficulties in treating this serious condition. [ABSTRACT FROM AUTHOR]

The carotid body, which is located bilaterally on the medial side of the carotid bifurcation, is the largest group of paraganglia in the head and neck. Chemoreceptor cells in the carotid bulb give rise to uncommon tumours known as Carotid Body Tumours (CBTs). The authors describe a case of a CBT in a 40-year-old woman who had a painful, pulsatile, lateral neck enlargement on the right side that had been developing over time. Due to the numerous difficulties and problems brought on by their high vascularity and close proximity to cranial nerves in the neck near the carotid bifurcation, they pose a surgical challenge. Based on the patient's medical history, the results of clinical and radiological examinations, and the successful surgical removal of the tumour, the diagnosis was suspected. The results of histological analysis supported the diagnosis of a CBT. [ABSTRACT FROM AUTHOR]

Background: Endoscopic biopsy are easy, less time consuming and OPD side procedure where no general anaesthesia is required or hospitalization is needed, is required for confirmation of diagnosis which is impossible by FNAC. Endoscopic biopsy permits the correct identification of lesion and taking out the biopsy from the same site. Objectives: 1. To study the spectra of various histopathological lesions in GIT with the help of endoscopic biopsy. 2. To prove endoscopic biopsies as an efficient tool for reaching correct diagnosis. Methodology - Cross sectional study will be carried out from August 2018 to August 2021 AVBRH Sawangi, Wardha, Maharashtra. Patients with gastrointestinal symptoms undergoing endoscopic / colonoscopic examination. The biopsy specimen will be processed and then will be paraffin embedded. Each section will be stained with Hematoxylin and Eosin as per standard protocol and studied microscopically. 100 endoscopic biopsies were examined during the study period. Expected Results – Results will be evaluated after the completion of the study using SPSS VERSION 21. Conclusion- The conclusion will be based on the results of study. [ABSTRACT FROM AUTHOR]