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Marine mudstone of Coniacian age (c. 89.51-86.49 Ma) was deposited on a storm-dominated ramp spanning the foredeep of the Cretaceous Western Canada Foreland Basin. Marine flooding surfaces define 18 allomembers that thin over 300 km, from c. 140 m in the proximal foredeep to c. 20 m close to the forebulge crest. The broadly conformable succession of allomembers is partitioned into five 'tectono-stratigraphic units' by low-angle unconformities that bevel off c. 10 to 20 m of strata over 'arches' that have a length scale of c. 50-100 km and are bounded by relatively linear zones of flexure. Depositional history involved two alternate modes: 'Background' deposition of subtly-tapered allomembers took place on a planar sea floor, subject to regional flexural subsidence, with sea-level modulated by Milankovitch-scale (c. 125 kyr) eustatic cycles. 'Flexural' events deformed the strata into troughs and arches across narrow zones of flexure. Arch crests were bevelled off, probably by submarine wave erosion. Eroded sediment did not accumulate in troughs but was advected beyond the study area by storm-driven processes. Cycles of deposition, warping and erosion were repeated five times on an average timescale of 600 kyr. Arches and troughs do not coincide with Precambrian basement structures, and their origin remains enigmatic. Changes in in-plane stress may have effected the localized vertical motion. [ABSTRACT FROM AUTHOR]

Discusses and defines computer-based instructional simulations based on a review and analysis of computer-based simulation studies found in the literature. Simulation studies are classified and analyzed according to the instructional function for which the simulation was used, and needed research is suggested. (36 references) (LRW)

Extreme weather events can cause severe disruption to transport systems, greatly reducing the ability to maintain important social and economic functions such as the delivery of goods and materials within the supply chain. There is a need for greater qualitative and quantitative understanding of how transport systems respond under adverse conditions, to inform event management and to aid adaptation actions. The present study uses the intense storms of 28 June 2012 as a case study to present a novel exploration of the impacts of an extreme event using high spatial and temporal resolution transport data for the UK road and rail networks, as well as weather data from the UK Meteorological Office's MIDAS surface station network and NIMROD weather radar. This event caused widespread disruption, severing the main rail links between England and Scotland and causing 10 000 delay minutes to train services throughout the country, as well as causing reduced speeds on local roads and motorways. The present study describes the meteorological situation in the build-up to and during the event, and uses Network Rail train delay data to visualize the way in which the failure of several sections of critical transport infrastructure caused disruption that propagated quickly through the rail network of Great Britain. Highway Agency motorway speed data are used to quantify the impact of this event on the M6 motorway in the West Midlands. Ways in which the insights gained from these data can be used to aid the transport sector in the prioritization of adaptation actions are discussed. [ABSTRACT FROM AUTHOR]

Exclusive enteral nutrition is established as an initial therapy to induce remission in active Crohn’s disease (CD), especially in children, but the mechanisms of action of this therapy are yet to be fully defined. CEACAM6 protein is an adhesion molecule that is up-regulated in active CD and implicated in the attachment of adherent-invasive Escherichia coli (AIEC) to the gut epithelium. Using the Caco-2 human adenocarcinoma cell line, this study showed that the incubation of human cells with a polymeric formula (PF) resulted in a dose-dependent increase in the expression of CEACAM6, and that this effect was most noticeable on the cell surface. Further investigation revealed that PF doubled the release of CEACAM6 protein by Caco-2 cells exposed to PF, and that an increase in release of soluble CEACAM6 inversely correlated with the ability of AIEC to associate with the intestinal epithelial cells. Our findings suggest that the secretion of cell surface-associated proteins acting as releasable decoys may be an aspect of the gut’s innate immune response to pathogenic bacteria that is strengthened by PF in the setting of CD. [ABSTRACT FROM PUBLISHER]

Climate change impact assessments require detailed information regarding the impact of weather in the current climate. This study focuses on the road network, using UK Highways Agency Traffic Information System data and NIMROD precipitation radar data to determine the impact of precipitation on traffic speeds along the M1 and M6 corridors for use in future impact assessments. The results show that whilst precipitation does impact on traffic speeds, there is no universal significant single factor relationship between the two variables and only a small amount of variance in traffic speeds can be explained by the intensity of precipitation. However, a threshold appears to exist simply at 0 mm h−1 (i.e. precipitation/no precipitation). The significance of this threshold is tested in this paper, but it appears clear that a universal relationship between precipitation intensity and vehicle speeds is unlikely to exist and local conditions such as capacity and drainage are equally as important to take into account. Copyright © 2012 Royal Meteorological Society [ABSTRACT FROM AUTHOR]

The fields of life care planning and psychology play a significant role together in assisting patients to receive the best care possible after an injury that has drastically changed their life. Neuropsychological and psychological assessments can aid the life care planner in determining the future needs of adult and pediatric patients. Testing assesses areas such as attention, cognitive decline, emotional functioning, intellectual ability, memory, and many other areas of functioning to provide a thorough picture of a person's current abilities, strengths, and weaknesses. It is important that life care planners understand psychological assessments and that psychologists provide useful information in their report that will aid others in knowing what type of care the patient will need. The objective of this article is to inform those in the life care planning field of the new developments in testing that may affect how one plans for the future care and treatment of their patient. [ABSTRACT FROM AUTHOR]

A naturalistic study was undertaken to explore six-year-old children's perceptions of work in their school day. Twenty-four Year One children enrolled in an infants' school, located in Southern Sydney were involved. Participant observation and focus group interviewing were used to elicit descriptive information. A fishing game, drawing activity and excerpts from a videotape of their day at school were used as stimuli to capture how children categorised and attributed meaning to their own work performance. The findings revealed that these children had well-developed ideas about what is work. They employed a highly individual classification process to determine which occupations were work versus play, self-care and rest, resulting in differences of opinion among the children. This process was based on four factors: the physical and social environment, the type of task being performed, personal meaning attributed to the task and the child's perceived level of control. [ABSTRACT FROM AUTHOR]

Assesses the effects of using a simulation of computer operations as an introduction to a beginning computer-programming course. Four replications of a simulation experiment; Influence of the simulation procedure on the student's choice of algorithms; Differences in knowledge of the syntax or ability to trace program segments.