Search

Your search keyword '"HORIKAWA, TATSUYA"' showing total 316 results
Start Over Author "HORIKAWA, TATSUYA"
316 results on '"HORIKAWA, TATSUYA"'

3. Solar Urticaria

Author

Horikawa, Tatsuya, Fukunaga, Atsushi, Nishigori, Chikako, Zuberbier, Torsten, editor, Grattan, Clive E. H., editor, and Maurer, Marcus, editor

Published
2010
Full Text
View/download PDF

19. Beneficial screening of Fabry disease in patients with hypohidrosis.

Author

Nagai‐Sangawa, Megumi, Fukunaga, Atsushi, Takeuchi, Chihiro, Nishiyama, Satoshi, Horikawa, Tatsuya, Nagano, China, Nozu, Kandai, Fujii, Hideki, and Nishigori, Chikako

Abstract

Fabry disease (FD), which is a lysosomal storage disease resulting from a deficiency of α‐galactosidase A, leads to the accumulation of globotriaosylceramide in various tissues and multiorgan impairment. Early diagnosis is important to improve long‐term prognosis. Early clinical manifestations of FD include neuropathic pain, vascular skin lesions, and sweating abnormalities. Hypohidorosis is one of the clinical findings in the early stage of FD. However, there have been no studies on prospective screening of FD in patients with definitive diagnosis of hypohidrosis. We examined α‐galactosidase A activity in white blood cells in 17 (one female and 16 male) patients with generalized hypohidorosis. Among 17 patients, one male patient (approximately 5.8%) had significantly reduced α‐galactosidase A activity. He presented with a history of hypohidrosis with heat intolerance and neuropathic tingling pain in a warm environment from 6 years ago. He had a few angiokeratoma on the trunk and extremities. Ultrastructural examination of skin biopsy from the angiokeratoma revealed lamellar inclusions in endothelial cells. Kidney biopsy revealed swollen podocytes and Gb3 deposition in the glomerulus, and urinalysis revealed mulberry bodies. He was finally diagnosed with FD and started on enzyme replacement therapy with agalsidase alpha in the early stage. In addition, his family screening led to find the patients of four additional FD. Screening for FD in patients with hypohidrosis may lead to efficient early detection of FD. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

24. Serum levels of CCL17/TARC in various skin diseases

Author

TAMAKI, Kunihiko, KAKINUMA, Takashi, SAEKI, Hidehisa, HORIKAWA, Tatsuya, KATAOKA, Youko, FUJISAWA, Takao, SATO, Shinichi, TAKEHARA, Kazuhiko, NAKAHARA, Takeshi, FUKAGAWA, Shuji, and FURUE, Masutaka

Published
2006

27. Mutation Analysis of the ADAR1 Gene in Dyschromatosis Symmetrica Hereditaria and Genetic Differentiation from both Dyschromatosis Universalis Hereditaria and Acropigmentatio Reticularis

Author

Suzuki, Noriyuki, Suzuki, Tamio, Inagaki, Katsuhiko, Ito, Shiro, Kono, Michihiro, Fukai, Kazuyoshi, Takama, Hiromichi, Sato, Kenji, Ishikawa, Osamu, Abe, Masatoshi, Shimizu, Hiroshi, Kawai, Masaaki, Horikawa, Tatsuya, Yoshida, Kunihiro, Matsumoto, Kazuhiko, Terui, Tadashi, Tsujioka, Kaoru, and Tomita, Yasushi

Published
2005

Catalog

Books, media, physical & digital resources
See catalog results