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Hypertensive disorders during pregnancy are a major public health concern in both developed and developing countries. Early detection and treatment of maternal health issues reduce the severity of these issues. This study set out to identify possible risk factors of these conditions and evaluate current methods of treatment. Throughout the research (6 months), 80 PIH women who met the inclusion criteria were studied in an observational study. Women in their twenties and thirties are more likely to have pregnancy-induced hypertension. Preeclampsia and gestational hypertension in pregnancy are the most common types. Hypertension issues are more common among pregnant women who are more likely to be obese, have had previous pregnancies, and reside in rural areas. Medication for the treatment of pregnancy-induced hypertension is prescribed and administered regarding drugs used for primary hypertension. Methyldopa and labetalol are examples of first-line treatments. Patients with PIH who are about to give birth are given hydralazine intravenously (IV) or nifedipine orally (P.O.) as a second-line treatment. When providing antihypertensive medicines or any other medications, the well-being of both maternal and fetal is taken into consideration. The risks to both mother and child may be reduced with prompt treatment with additional, safe medications.

Abstract Background Dietary and wholesome antioxidant rutin is considered advantageous due to its potential protective role for numerous diseases related to oxidative stress, high safety, cost-effectiveness, and extensive biological effects. The present study accounts for an expeditious method for the synthesis of silver nanoparticles (AgNPs) using rutin. Results The presence of AgNPs was affirmed by UV–visible spectroscopy at 425 nm, and FESEM and zeta sizer analysis revealed the average size of the AgNPs 80–85 nm and 160 d.nm, respectively. Zeta potential measurements (− 30.3 mV) showed that the AgNPs have reasonably good stability. Element mapping analysis of the AgNPs was confirmed by XRD and AFM, while FTIR spectra of the AgNPs showed the existence of functional groups. In the DPPH assay, highest radical scavenging activity of AgNPs, 86.95 ± 01.60%, was confirmed. The interaction of AgNPs with CT-DNA and HS-DNA was studied spectrophotometrically, and the data display a shift in the respective spectra. Furthermore, interaction with pBR322 DNA, λ DNA, CT-DNA, and HS-DNA was deliberated by a nicking assay that shows the physicochemical properties of AgNPs. Antibacterial activity was evaluated by the standard well-diffusion method against Escherichia coli and Staphylococcus aureus, and cytotoxicity was assessed against human WBCs by MTT assay. Conclusion As per this appraisal, it can be concluded that it is a cost-effective, simple, and eco-friendly tactic and such NPs are beneficial to improve therapeutics since the antioxidant, DNA interaction, antibacterial, and cytotoxic exploits offer a new horizon of euthenics.