189 results on '"Hagan, Jim J."'
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2. Chronic fluoxetine differentially modulates the hippocampal microtubular and serotonergic system in grouped and isolation reared rats
3. Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B
4. 5-HT6 receptor antagonists improve performance in an attentional set shifting task in rats
5. Localisation of NMU1R and NMU2R in human and rat central nervous system and effects of neuromedin-U following central administration in rats
6. Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats
7. Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation
8. Central effects of urotensin-II following ICV administration in rats
9. Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity
10. Enhanced Appetitive Learning and Reversal Learning in a Mouse Model for Prader-Willi Syndrome
11. In vitro and in vivo comparison of two non-peptide tachykinin NK3 receptor antagonists: Improvements in efficacy achieved through enhanced brain penetration or altered pharmacological characteristics
12. The behavioural effects of corticotropin-releasing factor-related peptides in rats
13. Behavioural and cognitive abnormalities in an imprinting centre deletion mouse model for Prader–Willi syndrome
14. Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving
15. SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain
16. Parkinson's disease: prospects for improved drug therapy
17. Predicting Drug Efficacy for Cognitive Deficits in Schizophrenia
18. Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus
19. Urotensin-II, a neuropeptide ligand for GPR14, induces c-fos in the rat brain
20. 5-HT 7 receptors modulate synchronized network activity in rat hippocampus
21. ( )-3, -Dimethyl- -[1-methyl-3-(4-methylpiperidin-1-yl)propyl]benzenesulfonamide: The First Selective 5-HT Receptor Antagonist
22. Drug repositioning for Alzheimer's disease
23. Transcription and pathway analysis of the superior temporal cortex and anterior prefrontal cortex in schizophrenia
24. N-desmethylclozapine (NDMC) is an antagonist at the human native muscarinic M1 receptor
25. Altered M1 Muscarinic Acetylcholine Receptor (CHRM1)-Gαq/11 Coupling in a Schizophrenia Endophenotype
26. Fluoxetine administration modulates the cytoskeletal microtubular system in the rat hippocampus
27. Studies towards the identification of a new generation of atypical antipsychotic agents
28. Pharmacological Assessment of M1 Muscarinic Acetylcholine Receptor-Gq/11 Protein Coupling in Membranes Prepared from Postmortem Human Brain Tissue
29. 1,2,4-Triazol-3-yl-thiopropyl-tetrahydrobenzazepines: A Series of Potent and Selective Dopamine D3 Receptor Antagonists
30. SB-649915-B, a Novel 5-HT1A/B Autoreceptor Antagonist and Serotonin Reuptake Inhibitor, is Anxiolytic and Displays Fast Onset Activity in the Rat High Light Social Interaction Test
31. Long-lasting changes in behavioural and neuroendocrine indices in the rat following neonatal maternal separation: Gender-dependent effects
32. The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence
33. Effect of the acute and chronic administration of the selective 5-HT6 receptor antagonist SB-271046 on the activity of midbrain dopamine neurons in rats: An in vivo electrophysiological study
34. The 5-HT6 Receptor Antagonist SB-271046 Reverses Scopolamine-Disrupted Consolidation of a Passive Avoidance Task and Ameliorates Spatial Task Deficits in Aged Rats
35. Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist
36. SB-656104-A, a novel selective 5-HT7receptor antagonist, modulates REM sleep in rats
37. Acute administration of the selective D3 receptor antagonist SB-277011A blocks the acquisition and expression of the conditioned place preference response to heroin in male rats
38. Selective Antagonism at Dopamine D3 Receptors Prevents Nicotine-Triggered Relapse to Nicotine-Seeking Behavior
39. 5-HT6 receptor antagonist SB-271046 enhances extracellular levels of monoamines in the rat medial prefrontal cortex
40. Selective Antagonism at Dopamine D3 Receptors Enhances Monoaminergic and Cholinergic Neurotransmission in the Rat Anterior Cingulate Cortex
41. Dopamine D3Receptor Antagonism Inhibits Cocaine-Seeking and Cocaine-Enhanced Brain Reward in Rats
42. Attenuation of Cue-Controlled Cocaine-Seeking by a Selective D3 Dopamine Receptor Antagonist SB-277011-A
43. 5-HT7 receptors modulate synchronized network activity in rat hippocampus
44. The effect of SB-269970, a 5-HT7receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies
45. Characterization of SB-269970-A, a selective 5-HT7receptor antagonist
46. [3H]-SB-269970 - A selective antagonist radioligand for 5-HT7receptors
47. Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat
48. Evaluation of the spontaneously hypertensive rat as a model of attention deficit hyperactivity disorder: acquisition and performance of the DRL-60s test
49. A Novel, Potent, and Selective 5-HT7 Antagonist: (R)-3-(2-(2-(4-Methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
50. Practical and Theoretical Issues in Gene-Targeting Studies and their Application to Behaviour
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