Search

Your search keyword '"Haggiagi, Aya M."' showing total 4 results
Start Over Author "Haggiagi, Aya M."
4 results on '"Haggiagi, Aya M."'

1. ONC201 (Dordaviprone) in Recurrent H3 K27M–Mutant Diffuse Midline Glioma

Author

Arrillaga-Romany, Isabel, primary, Gardner, Sharon L., additional, Odia, Yazmin, additional, Aguilera, Dolly, additional, Allen, Joshua E., additional, Batchelor, Tracy, additional, Butowski, Nicholas, additional, Chen, Clark, additional, Cloughesy, Timothy, additional, Cluster, Andrew, additional, de Groot, John, additional, Dixit, Karan S., additional, Graber, Jerome J., additional, Haggiagi, Aya M., additional, Harrison, Rebecca A., additional, Kheradpour, Albert, additional, Kilburn, Lindsay B., additional, Kurz, Sylvia C., additional, Lu, Guangrong, additional, MacDonald, Tobey J., additional, Mehta, Minesh, additional, Melemed, Allen S., additional, Nghiemphu, Phioanh Leia, additional, Ramage, Samuel C., additional, Shonka, Nicole, additional, Sumrall, Ashley, additional, Tarapore, Rohinton S., additional, Taylor, Lynne, additional, Umemura, Yoshie, additional, and Wen, Patrick Y., additional

Published
2024
Full Text
View/download PDF

3. Primary large B-cell lymphoma of the central nervous system with cyclin D1 expression and t(11;14) (IGH-CCND1): Diffuse large B-cell lymphoma with CCND1 rearrangement or mantle cell lymphoma?

Author

Parrott, Andrew M., Haggiagi, Aya M., Vundavalli, Murty V., Bhagat, Govind, and Alobeid, Bachir

Subjects
Oncology, immune system diseases, hemic and lymphatic diseases, Lymphomas, neoplasms
Abstract

Mantle cell lymphomas (MCLs) are the prototypic B-cell non-Hodgkin lymphomas defined by cyclin D1 gene (CCND1; or other cyclin D family gene) rearrangements. However, extremely rare cases of diffuse large B-cell lymphomas (DLBCLs) harboring CCND1 rearrangements, resulting in cyclin D1 protein expression, have also been reported. In this report, we describe an unusual primary large B-cell lymphoma of non-germinal center immunophenotype of the central nervous system (CNS) in an elderly male patient, which was negative for CD5 and SOX11, and exhibited cyclin D1 expression. Fluorescence in situ hybridization analysis detected IGH-CCND1 and BCL6 rearrangements. This case may represent the first report of a primary CNS DLBCL with IGH-CCND1 rearrangement. The clinico-pathologic features that can help differentiate primary CNS MCL from primary DLBCL of the CNS with IGH-CCND1 rearrangement are discussed.

Published
2020
Full Text
View/download PDF

4. Primary large B-cell lymphoma of the central nervous system with cyclin D1 expression and t(11;14) (IGH-CCND1): Diffuse large B-cell lymphoma with CCND1 rearrangement or mantle cell lymphoma?

Author

Parrott AM, Haggiagi AM, Murty VV, Bhagat G, and Alobeid B

Subjects
Aged, 80 and over, Biomarkers, Tumor, Biopsy, Gene Expression, Humans, Immunohistochemistry, Immunophenotyping, In Situ Hybridization, Fluorescence, Lymphoma, Mantle-Cell diagnosis, Lymphoma, Mantle-Cell genetics, Lymphoma, Mantle-Cell therapy, Magnetic Resonance Imaging, Male, Central Nervous System Neoplasms diagnosis, Central Nervous System Neoplasms genetics, Cyclin D1 genetics, Gene Rearrangement, Lymphoma, Large B-Cell, Diffuse diagnosis, Lymphoma, Large B-Cell, Diffuse genetics, Oncogene Proteins, Fusion genetics
Abstract

Mantle cell lymphomas (MCLs) are the prototypic B-cell non-Hodgkin lymphomas defined by cyclin D1 gene (CCND1; or other cyclin D family gene) rearrangements. However, extremely rare cases of diffuse large B-cell lymphomas (DLBCLs) harboring CCND1 rearrangements, resulting in cyclin D1 protein expression, have also been reported. In this report, we describe an unusual primary large B-cell lymphoma of non-germinal center immunophenotype of the central nervous system (CNS) in an elderly male patient, which was negative for CD5 and SOX11, and exhibited cyclin D1 expression. Fluorescence in situ hybridization analysis detected IGH-CCND1 and BCL6 rearrangements. This case may represent the first report of a primary CNS DLBCL with IGH-CCND1 rearrangement. The clinico-pathologic features that can help differentiate primary CNS MCL from primary DLBCL of the CNS with IGH-CCND1 rearrangement are discussed., (© 2020 John Wiley & Sons Ltd.)

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results