34 results on '"Hai-Rong Liu"'
Search Results
2. Simulation on microstructure evolution and mechanical properties of Mg−Y alloys: Effect of trace Y
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Wei LIU, Bo-qiang WU, Hai-rong LIU, Rang-su LIU, Yun-fei MO, Ze-an TIAN, Zhao-yang HOU, Ting-fei XI, Zhi-yi WAN, Chang-xiong HUANG, and Xin CHEN
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Materials Chemistry ,Metals and Alloys ,Geotechnical Engineering and Engineering Geology ,Condensed Matter Physics - Published
- 2022
3. Existence and uniqueness of optimal transport maps obtained by the secondary variational method
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Hai-Rong Liu, Ping Chen, and Xiao-Ping Yang
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Variational method ,General Mathematics ,Applied mathematics ,Uniqueness ,Mathematics - Published
- 2021
4. Analysis of Prognostic Factors of Nasopharyngeal Carcinoma and Construction of Risk Nomogram Prediction Model
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zhang, xuan hao, primary, Jin, LU, additional, Cheng-yi, JIANG, additional, Mei-fang, FANG, additional, and Hai-rong, Liu, additional
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- 2021
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5. Factors Affecting Infection Control Behaviors to Prevent COVID-19: An Online Survey of Nursing Students in Anhui, China in March and April 2020
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Hai Rong Liu, Ting Yuan, Huan Liu, and Xiang Dong Li
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Male ,medicine.medical_specialty ,China ,Health Knowledge, Attitudes, Practice ,media_common.quotation_subject ,education ,Health Behavior ,Pneumonia, Viral ,030204 cardiovascular system & hematology ,Literacy ,Statistics, Nonparametric ,03 medical and health sciences ,Betacoronavirus ,Young Adult ,0302 clinical medicine ,Nursing ,Clinical Research ,Surveys and Questionnaires ,eHealth ,medicine ,Humans ,Pandemics ,media_common ,Multinomial logistic regression ,Internet ,Descriptive statistics ,SARS-CoV-2 ,Public health ,COVID-19 ,General Medicine ,Odds ratio ,Logistic Models ,Knowledge ,Attitude ,030220 oncology & carcinogenesis ,Health education ,Female ,Students, Nursing ,Rural area ,Psychology ,Coronavirus Infections - Abstract
BACKGROUND The pandemic of coronavirus disease 2019 (COVID-19) has become a major public health challenge all over the world. People's knowledge, attitudes, and preventive behaviors about diseases affect the degree of adherence to control measures. This study aimed to survey the affecting factors of COVID-19 prevention behavior among nursing students in China. MATERIAL AND METHODS Six-hundred thirteen nursing students in Anhui, China participated in an online survey from March 30 to April 5, 2020. The survey collected demographic information, electronic health (eHealth) literacy, COVID-19-related knowledge, attitudes, and prevention behavior data using descriptive analysis and multinomial logistic regression to analyze the data. RESULTS The mean age of study participants was 20.88 years, of which 31.8% were male (n=613). Television (84.9%) and WeChat (79.6%) were the major sources of their information. Nursing students had good knowledge (14.68±2.83), had positive attitudes (4.03±0.59), had good practices (3.92±0.65), and had basic eHealth literacy (30.45±6.90). Nursing students with higher eHealth literacy (odds ratio [OR]=0.89, P
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- 2020
6. Emotional responses and coping strategies of nurses and nursing college students during COVID-19 outbreak
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Long Huang, Fu ming xu, and Hai rong Liu
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Coping (psychology) ,Medical staff ,Coronavirus disease 2019 (COVID-19) ,media_common.quotation_subject ,Outbreak ,Computer-assisted web interviewing ,Anger ,Sadness ,Nursing ,medicine ,Anxiety ,medicine.symptom ,Psychology ,media_common - Abstract
BackgroundAffected by a Corona Virus Disease 2019 (COVID-19) outbreak, Since December 2019, there have been more than 76,000 cases of COVID-19 in China, causing more than 3,000 medical staff infections. Due to COVID-19 spreads quickly, is highly contagious, and can be fatal in severe cases, and there are no specific medicines, it poses a huge threat to the life and health of nurses and has a large impact on their emotional responses and coping strategies.MethodsThis study conducted an online questionnaire survey from February 1 to 9, 2020 to investigate the current state of emotional responses and coping strategies of nurses and college nursing students in Anhui Province. This study used a modified Brief COPE (Carver, 1997) and a emotional responses scale.ResultsThe results found that women showed more severe anxiety and fear than men. Participants from cities showed more anxiety and fear than participants from rural, but rural participants showed more sadness than urban participants. The closer COVID-19 is to the participants, the stronger the anxiety and anger. Compared with Nursing college students, nurses have stronger emotional responses and are more willing to use Problem-focused coping. People may have a cycle of “the more fear, the more problem-focused coping”. And people may “The more angry, the more emotion-focused coping”, “the more problem-focused coping, the more anxious, the more angry, the more sadness”.ConclusionCOVID-19 is a pressure source with great influence, both for individuals and for the social public groups. Different individuals and groups may experience different levels of psychological crisis, and those nurses at the core of the incident are affected. Hospitals should focus on providing psychological support to nurses and providing timely psychological assistance and training in coping strategies.Improving nurses’ ability to regulate emotions and effective coping strategies, providing a strong guarantee for resolutely winning the battle against epidemic prevention and control.
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- 2020
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7. Two novel Co(II)-based coordination polymers with hms and pcu nets: syntheses, structures and properties
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Wei-Qiu Kan, Na Xu, Jinmao You, Hai-Rong Liu, Yuan-Chun He, and Fang-Hua Zhao
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chemistry.chemical_classification ,Thermogravimetric analysis ,010405 organic chemistry ,Chemistry ,Infrared ,Coordination polymer ,Crystal structure ,Polymer ,010402 general chemistry ,01 natural sciences ,Hydrothermal circulation ,0104 chemical sciences ,Inorganic Chemistry ,Crystallography ,chemistry.chemical_compound ,Diffuse reflectance spectra ,Materials Chemistry ,Organic chemistry ,Physical and Theoretical Chemistry ,Single crystal - Abstract
Two new Co(II)-based coordination polymers, [Co(HL)(H2O)2] (1) and [Co(HL)(bpy)]·H2O (2) (H3L = 5-((4-carboxyphenoxy)methyl)benzene-1,3-dioic acid, bpy = 4,4′-bipyridine), have been synthesized under hydrothermal conditions. The two compounds have been characterized by single crystal and powder X-ray diffraction analyses, infrared analyses, elemental analyses and thermogravimetric analyses. Compound 1 shows a 3D 2-fold interpenetrating hms framework, whereas compound 2 reveals a typical 3D pcu net. The UV–vis diffuse reflectance spectra of compounds 1 and 2 have been investigated. Moreover, the magnetic susceptibilities of compounds 1 and 2 have been studied.
- Published
- 2017
8. Emerging role of adipokines in systemic lupus erythematosus
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Hai-Feng Pan, Dong-Qing Ye, Rui-Xue Leng, Xiao-Mei Li, Hong-Miao Li, Hai-Rong Liu, Xiang-Pei Li, and Tian-Ping Zhang
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Leptin ,0301 basic medicine ,Chemokine ,Immunology ,Adipokine ,Adipose tissue ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Adipokines ,immune system diseases ,Animals ,Humans ,Lupus Erythematosus, Systemic ,Chemerin ,Medicine ,Resistin ,Molecular Targeted Therapy ,skin and connective tissue diseases ,030203 arthritis & rheumatology ,biology ,Adiponectin ,business.industry ,nutritional and metabolic diseases ,030104 developmental biology ,Adipose Tissue ,biology.protein ,Intercellular Signaling Peptides and Proteins ,Chemokines ,business ,hormones, hormone substitutes, and hormone antagonists - Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder characterized by multisystem organ involvement and unclear pathogenesis. Several adipokines synthesized in the adipose tissue, including leptin, adiponectin, resistin, and chemerin, have been explored in autoimmune rheumatic diseases, especially SLE, and results suggest that these mediators may be implicated in the pathogenesis of SLE. However, the current results are controversial. In this review, we will briefly discuss the expression and possible pathogenic role of several important adipokines, including leptin, adiponectin, resistin, and chemerin in SLE.
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- 2016
9. Subclinical atherosclerosis in patients with systemic lupus erythematosus: A systemic review and meta-analysis
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Hai-Rong Liu, Hai-Feng Pan, Dong-Qing Ye, Xiang-Pei Li, Xiao-Mei Li, Rui-Xue Leng, and Guo-Cui Wu
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Funnel plot ,medicine.medical_specialty ,Immunology ,Disease ,030204 cardiovascular system & hematology ,Carotid Intima-Media Thickness ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Prevalence ,Humans ,Lupus Erythematosus, Systemic ,Immunology and Allergy ,Medicine ,cardiovascular diseases ,skin and connective tissue diseases ,030203 arthritis & rheumatology ,business.industry ,Publication bias ,Odds ratio ,Atherosclerosis ,Intima-media thickness ,Meta-analysis ,Subclinical atherosclerosis ,cardiovascular system ,Observational study ,business ,Biomarkers - Abstract
Systemic lupus erythematosus (SLE) is associated with increased risk of cardiovascular disease. Carotid intima media thickness (CIMT) and carotid plaques are both frequently used to identify populations at higher cardiovascular risk. A systematic literature search and meta-analysis were performed to evaluate CIMT and carotid plaques difference between SLE patients and normal controls.The literatures comparing markers of cardiovascular risk (CIMT and prevalence of carotid plaques) in SLE and controls were systematically searched in PubMed, EMBASE and Cochrane databases. The overall mean CIMT difference and pooled odds ratio (OR) for the prevalence of carotid plaques between SLE patients and control groups were calculated by fixed-effects or random-effect model analysis. Meta-regression was performed to explore the potential influencing factors. Publication bias was examined by a funnel plot and Egger's test.A total of 80 studies (6085 SLE patients and 4794 controls) were included in the final analysis, 71 studies with data on CIMT (4814 cases and 3773 controls) and 44 studies reporting on the prevalence of carotid plaques (4417 cases and 3528 controls). As compared to controls, SLE patients showed a higher CIMT (WMD: 0.07 mm; 95%CI: 0.06, 0.09; P0.001), and an increased prevalence of carotid plaques (OR: 2.45; 95%CI: 2.02, 2.97; P0.001). Meta-regression models showed that traditional cardiovascular risk factors (age, HDL and triglyceride of SLE patients) and lupus related risk factors (as expressed by duration, ESR, SLEDAI and steroids) had a significant influence on CIMT, steroids and triglyceride had significant influence on the prevalence of carotid plaques.Our findings support the current evidence base for an increased cardiovascular burden in SLE patients and support the use of CIMT and carotid plaques in observational studies in SLE patients. The findings are of importance to design more specific prevention and treatment strategies.
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- 2016
10. Histopathology of melanosis coli and determination of its associated genes by comparative analysisof expression microarrays
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Long Gao, Hai‑Rong Liu, Shu‑Χian Zhou, Xiao‑Αn Li, Xiao‑Hui Li, Xian Jing Yu, Yan Zhou, and Jin‑Mei Xu
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Male ,Cancer Research ,Pathology ,CYP3A4 ,Apoptosis ,Biochemistry ,Severity of Illness Index ,Melanosis ,Intestinal mucosa ,Melanosis coli ,Cytochrome P-450 CYP3A ,pigmentation ,Glucuronosyltransferase ,Intestinal Mucosa ,Oligonucleotide Array Sequence Analysis ,Comparative Genomic Hybridization ,medicine.diagnostic_test ,expression microarray ,melanosis coli ,Articles ,Middle Aged ,medicine.anatomical_structure ,Oncology ,Molecular Medicine ,Female ,Aryl Hydrocarbon Hydroxylases ,Adult ,medicine.medical_specialty ,Colon ,Biology ,Immunofluorescence ,Lipofuscin ,Genetics ,medicine ,Humans ,Molecular Biology ,Aged ,Lamina propria ,laxatives ,Microarray analysis techniques ,Gene Expression Profiling ,Macrophages ,Molecular Sequence Annotation ,DNA ,medicine.disease ,Molecular biology ,Gene expression profiling ,Gene Expression Regulation - Abstract
Melanosis coli (MC) refers to the condition characterized by abnormal brown or black pigmentation deposits on the colonic mucosa. However, the histopathological findings and genes associated with the pathogenesis of melanosis coli remain to be fully elucidated. The present study aimed to examine the histopathological features and differentially expressed genes of MC. This involved performing hematoxylin and eosin staining, specific staining and immunohistochemistry on tissues sections, which were isolated from patients diagnosed with MC. DNA expression microarray analysis, western blotting and immunofluorescence assays were performed to analyze the differentially expressed genes of melanosis coli. The results demonstrated that the pigment deposits in MC consisted of lipofuscin. A TUNEL assay revealed that a substantial number of apoptotic cells were present within the macrophages and superficial lamina propria of the colonic epithelium. Expression microarray analysis revealed that the significantly downregulated genes were CYP3A4, CYP3A7, UGT2B11 and UGT2B15 in melanosis coli. Western blotting and immunofluorescence assays indicated that the expression of CYP3A4 in the normal tissue was higher than in the MC tissue. The results of the present study provided a comprehensive description of the histopathological characteristics and pathogenesis of MC and for the first time, to the best of our knowledge, demonstrated that the cytochrome P450‑associated genes were significantly downregulated in melanosis coli. This novel information can be used to assist in further investigations of melanosis coli.
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- 2015
11. Fully human HER2/cluster of differentiation 3 bispecific antibody triggers potent and specific cytotoxicity of T lymphocytes against breast cancer
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Yan Zhou, Zhi‑Hui Guo, Shu‑Xian Zhou, Jin‑Liang Yang, Xiao‑An Li, Lan‑Tu Gou, Hai‑Rong Liu, and Jiang‑Man Wang
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Cancer Research ,CD3 Complex ,Receptor, ErbB-2 ,medicine.medical_treatment ,CD3 ,Primary Cell Culture ,Breast Neoplasms ,CHO Cells ,cluster of differentiation 3 ,Lymphocyte Activation ,Biochemistry ,breast cancer ,Cricetulus ,Lymphocytes, Tumor-Infiltrating ,HER2 ,Cricetinae ,Antibodies, Bispecific ,Genetics ,medicine ,Single-chain variable fragment ,Animals ,Humans ,Cytotoxicity ,skin and connective tissue diseases ,Molecular Biology ,neoplasms ,biology ,Cluster of differentiation ,Chinese hamster ovary cell ,Cancer ,Immunotherapy ,Articles ,medicine.disease ,Molecular biology ,bispecific antibody ,Oncology ,biology.protein ,Molecular Medicine ,Female ,Antibody ,T-Lymphocytes, Cytotoxic - Abstract
The use of a bispecific antibody (BsAb) is a promising and highly specific approach to cancer therapy. In the present study, a fully human recombinant single chain variable fragment BsAb against human epidermal growth factor receptor (HER)2 and cluster of differentiation (CD)3 was constructed with the aim of developing an effective treatment for breast cancer. HER2/CD3 BsAb was expressed in Chinese hamster ovary cells and purified via nickel column chromatography. Flow cytometry revealed that the HER2/CD3 BsAb was able to specifically bind to HER2 and CD3-positive cells. HER2/CD3 BsAb was able to stimulate T-cell activation and induce the lysis of cultured SKBR-3 and BT474 cells in the presence of unstimulated T lymphocytes. HER2/CD3 BsAb efficiently inhibited the growth of breast cancer tissue by activating and inducing the proliferation of tumor tissue infiltrating lymphocytes. Therefore, HER2/CD3 BsAb is a potent tool which may be a suitable candidate for the treatment of breast cancer.
- Published
- 2015
12. Factors Affecting Infection Control Behaviors to Prevent COVID-19: An Online Survey of Nursing Students in Anhui, China in March and April 2020.
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Ting Yuan, Huan Liu, Xiang Dong Li, and Hai Rong Liu
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- 2020
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13. Differentiation of rat adipose-derived mesenchymal stem cells into corneal-like epithelial cells driven by PAX6
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Bing‑Yin Su, Feng Mei Deng, Hai‑Rong Liu, Jiang Wu, Ke Wen, Yong‑Hui Luo, Hong Zhang, Yi-Lun Liu, Wei-Hua Liu, and Jing Sun
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0301 basic medicine ,Cancer Research ,Cellular differentiation ,paired box 6 ,03 medical and health sciences ,0302 clinical medicine ,Immunology and Microbiology (miscellaneous) ,medicine ,Corneal epithelium ,Stem cell transplantation for articular cartilage repair ,adipose-derived mesenchymal stem cells ,Chemistry ,Mesenchymal stem cell ,Amniotic stem cells ,General Medicine ,Transfection ,Articles ,Molecular biology ,eye diseases ,corneal-like epithelial cells ,Transplantation ,030104 developmental biology ,medicine.anatomical_structure ,030221 ophthalmology & optometry ,sense organs ,Stem cell - Abstract
Corneal integrity, transparency and vision acuity are maintained by corneal epithelial cells (CECs), which are continuously renewed by corneal limbal stem cells (LSCs). Deficiency of CECs and/or LSCs is associated with numerous ocular diseases. Paired box (PAX)6 is an eye development-associated transcription factor that is necessary for cell fate determination and differentiation of LSCs and CECs. In the present study, the PAX6 gene was introduced into adipose-derived rat mesenchymal stem cells (ADMSCs) to investigate whether PAX6-transfected cells were able to transdifferentiate into corneal-like epithelial cells and to further verify whether the cells were suitable as a cell source for corneal transplantation. The ADMSCs were isolated from the bilateral inguinal region of healthy Sprague Dawley rats. The characteristics of ADMSCs were identified using flow cytometric analysis. After subculture, ADMSCs underwent transfection with recombinant plasmid containing either PAX6-enhanced green fluorescent protein (EGFP) complementary (c)DNA or EGFP cDNA (blank plasmid group), followed by selection with G418 and determination of the transfection efficiency. Subsequently, the morphology of the ADMSCs and the expression profiles of corneal-specific markers CK3/12 and epithelial-specific adhesion protein were determined. E-cadherin was detected using immunofluorescence staining and western blot analysis at 21 days following transfection. An MTT cell proliferation and a colony formation assay were performed to assess the proliferative activity and clonogenicity of PAX6-transfected ADMSCs. Finally, the PAX6-expressing ADMSCs were transplanted onto the cornea of a rabbits with limbal stem cell deficiency (LSCD). At 21 days after transfection, the ADMSCs with PAX6 transfection exhibited a characteristic flagstone-like appearance with assembled corneal-like epithelial cells, and concomitant prominent expression of the corneal-specific markers cytokeratin 3/12 and E-cadherin. Furthermore, the proliferation and colony formation ability of PAX6-overexpressing ADMSCs was significantly retarded. The transplantation experiment indicated that PAX6-reprogramed ADMSCs attached to and replenished the damaged cornea via formation of stratified corneal epithelium. Taken together, these results suggested that conversion of ADMSCs into corneal-like epithelium may be driven by PAX6 transfection, which makes ADMSCs a promising cell candidate for the treatment of LSCD.
- Published
- 2017
14. Formation mechanism of critical nucleus during nucleation process of liquid metal sodium.
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Zhao-yang Hou, Rang-su Liu, Hai-rong Liu, Ze-an Tian, Xin Wang, Qun-yi Zhou, and Zhen-hua Chen
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MOLECULAR dynamics ,NUCLEATION ,PHYSICAL & theoretical chemistry ,LIQUID sodium ,LIQUID metals ,MICROSTRUCTURE ,MICROMECHANICS - Abstract
To deeply understand the formation mechanism of a critical nucleus during the nucleation process of liquid metal sodium, a system consisting of 10 000 Na atoms has been simulated by using molecular dynamics method. The evolutions of nuclei are traced directly, adopting the cluster-type index method. It is found that the energies of clusters and their geometrical constraints interplay to form the favorable microstructures during the nucleation process. The nucleus can be formed through many different pathways, and the critical size of the nucleus would be different for each pathway. It is also found that the critical nucleus is nonspherical and may include some metastable structures. Furthermore, the size of the cluster and its internal structure both play a crucial role in determining whether it is a critical nucleus, and this is in agreement with the simulations by computing the free energy of the Lennard-Jones system [D. Moroni, P. R. ten Wolde, and P. G. Bolhuis, Phys. Rev. Lett. 94, 235703 (2005)]. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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15. Formation and evolution of metastable bcc phase during solidification of liquid Ag: a molecular dynamics simulation study
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Ze-An Tian, Rang-Su Liu, Cai-Xing Zheng, Hai-Rong Liu, Zhao-Yang Hou, and Ping Peng
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Copper alloys -- Thermal properties ,Copper alloys -- Chemical properties ,Molecular dynamics -- Usage ,Transition temperature -- Evaluation ,Silver -- Thermal properties ,Silver -- Chemical properties ,Chemicals, plastics and rubber industries - Published
- 2008
16. Structure and Antibacterial Properties of Ag-Doped TiO2 Porous Materials
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Yi Lin, Li Song, Hai Rong Liu, Qi Chen, and Rei Fang Ye
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Anatase ,Materials science ,Mechanical Engineering ,Infrared spectroscopy ,Polyethylene glycol ,chemistry.chemical_compound ,Chemical engineering ,chemistry ,Mechanics of Materials ,Phase (matter) ,General Materials Science ,Composite material ,Porosity ,Thermal analysis ,Porous medium ,Sol-gel - Abstract
Antibacterial Ag-doped TiO2 porous monolithics were firstly prepared by hybridization of polyethylene glycol, Ti(OC4H9)4 and AgNO3 via sol-gel method following by heat-treatment to remove the organic components. Thermogravimeter−differential thermal analysis, pore structure, infrared spectra, ultraviolet−visible spectra, release speed of silver ions into 30°C water and antibacterial properties of Ag-doped TiO2 samples made at different temperature were studied. The results showed that anatase phase and uniform pore structure can be formed after heated at 500°C. Ag+ ions from the samples heated at 500°C were stably released into water at 30°C up to 14 days. The material treated at 500°C has the best antibacterial property and can restrain Escherichia coli effectively.
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- 2007
17. Nanocrystalline NiO thin film anode with MgO coating for Li-ion batteries
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Shen-Jiang Yu, Yafei Zhang, Qi-Zong Qin, Ying Wang, and Hai-Rong Liu
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Materials science ,Scanning electron microscope ,General Chemical Engineering ,Non-blocking I/O ,Inorganic chemistry ,engineering.material ,Electrochemistry ,Nanocrystalline material ,Anode ,Coating ,Chemical engineering ,Electrode ,engineering ,Thin film - Abstract
The nanocrystalline NiO thin films with the mean size of ∼30 nm are prepared by pulsed laser reactive ablation in an oxygen ambient and subsequent coated by MgO on the NiO film surface. As compared with bare NiO, coated NiO film electrode heat-treated at 500 ◦ C exhibits excellent structural stability and electrochemical performance. Excellent electrochemical performance, a reversible capacity as high as 650 mAh/g in the range 0.01–3.0 V at high discharge rate of 2C with a high capacity retention up to 150 cycles, could be achieved with MgO-coated NiO films. Preliminary electrochemical cycling measurements show that capacity retention with capacity fading for bare NiO and MgO-coated NiO film electrodes are ∼0.43 and 0.28% per cycle, respectively, at the discharge rate of 2C after 150 cycles. This result is related to good structural stability of the MgO-coated NiO film as verified by cyclic voltammetric (CV) measurement and scanning electron microscopy (SEM) analysis. © 2003 Elsevier Ltd. All rights reserved.
- Published
- 2003
18. Characterization and preparation of NiO-V2O5 composite film cathodes
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Qi-Zong Qin, Yan-Qiu Chu, Hai-Rong Liu, and Zheng-Wen Fu
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Materials science ,Renewable Energy, Sustainability and the Environment ,Scanning electron microscope ,Nickel oxide ,Composite number ,Non-blocking I/O ,Energy Engineering and Power Technology ,Mineralogy ,Amorphous solid ,Pulsed laser deposition ,Crystallinity ,Chemical engineering ,Electrical and Electronic Engineering ,Physical and Theoretical Chemistry ,Thin film - Abstract
NiO-V 2 O 5 composite films have been fabricated by 355 nm pulsed laser reactive deposition using mixed metallic Ni and V targets with different molar ratios. The optimal deposition conditions of NiO-V 2 O 5 composite films are found to be the substrate temperature of 300 °C and 100 mTorr O 2 ambient. X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses showed that the crystallinity of the NiO-V 2 O 5 composite films gradually decreased with increasing the amount of nickel oxide and transformed to amorphous phase as the molar ratio of NiO/V 2 O 5 ( x ) approaches 0.5. The amorphous (NiO) 0.5 V 2 O 5 composite film electrode exhibited a specific capacity of 340 mAh/g at a discharge rate of 2 C upon cycling with no obvious fading up to 500 cycles. XRD and X-ray photo-electron spectroscopy (XPS) measurements of NiO-V 2 O 5 composite film electrodes revealed that there exists two electrochemical processes upon cycling. During the first discharge, the Li ions insertion process is accompanied by the reduction of NiO into metallic Ni. Then, the reversible processes involving Li ions insertion/extraction in V 2 O 5 matrix and oxidation/reduction of Ni and Li 2 O take place upon the subsequent cycling.
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- 2003
19. Design and Analysis of 2D Photonic Crystal Waveguides for High Coupling Efficiency
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Wei Jun Tong, De Xiu Huang, Ming Wu, and Hai Rong Liu
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Waveguide (electromagnetism) ,Materials science ,business.industry ,General Engineering ,Finite-difference time-domain method ,Physics::Optics ,Radius ,Yablonovite ,Wavelength ,Optics ,Photonic crystal waveguides ,Coupling efficiency ,business ,Dielectric waveguides - Abstract
In this paper we have proposed a photonic crystal structure to enhance the coupling efficiency between photonic crystal waveguide (PCW) and the conventional dielectric waveguide. The proposed waveguide characterized with employing the taper structure and varying the holes’ radius in the taper. Two-dimensional (2D) finite-difference time-domain (FDTD) method has been used to analyze the structure. The simulation results show that the coupling efficiency can be achieved as high as 81.6% at the wavelength of 1.55um.
- Published
- 2007
20. Protective effect of Radix Aucklandiae against ulcerative colitis in rats
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Jin Yang, Fang Tang, Lu Ma, Hai-Rong Liu, and Yong Zhang
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0301 basic medicine ,medicine.medical_specialty ,business.industry ,medicine.disease ,Gastroenterology ,Ulcerative colitis ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Radix ,business - Published
- 2016
21. [Preparation of polyclonal antibody of human endothelial-overexpressed lipopolysaccharide-associated factor 1]
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Yue-Ming, Liu, Hai-Rong, Liu, Zhen, Cai, Bing, Ma, Yi-Lun, Liu, and Wei, Zhang
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Lipopolysaccharides ,Mice ,Human Umbilical Vein Endothelial Cells ,Animals ,Humans ,Membrane Proteins ,Antibodies ,Cells, Cultured - Abstract
To prepare the polyclonal antibody of human endothelial-overexpressed lipopolysaccharide-associated factor 1 (EOLA1), and to determine the expression of EOLA1 in human umbilical vein endothelial cell (HUVEC).The protein samples (sample 1 and 2) expressing EOLA1 were purified and renatured. The protein concentrations were determined with bicinchoninic acid assay. The protein samples were identified with peptide mass fingerprinting (PMF) analysis. Protein sample with higher coincidence rate of amino acid sequence with theoretic protein was used to inoculate 4 mice; another 4 mice inoculated with adjuvant were used as control. Serum was isolated from collected mice blood. Polyclonal antibody of EOLA1 was purified with saturated ammonium sulfate precipitation, and was determined with ELISA for the titer (data were denoted by absorbance value). The expression of EOLA1 in HUVEC was determined with Western blot.The concentration of protein sample 1 and 2 was respectively 0.124 16 mg/mL and 0.132 15 mg/mL. According to PMF analysis, the coincidence rate of amino acid sequence between protein samples and theoretic protein were 32% (protein sample 1) and 24% (protein sample 2). The polyclonal antibody of EOLA1 with titer more than 1:10 000 was obtained from mice inoculated with protein sample 1. The expression of EOLA1 protein in HUVEC was determined with polyclonal antibody of EOLA1.The polyclonal antibody of EOLA1 can be prepared by inoculating mice with EOLA1 prokaryotic expressing protein, which can be used for determination of EOLA1 protein.
- Published
- 2011
22. [The mid- or long-term clinical results of prosthetic disc nucleus replacement in the treatment of lumbar disc disease]
- Author
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Yuan-zheng, Ma, Hai-bin, Xue, Xing, Chen, Li-xin, Guo, Hong-wei, Li, and Hai-rong, Liu
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Adult ,Male ,Lumbar Vertebrae ,Joint Prosthesis ,Middle Aged ,Treatment Outcome ,Humans ,Female ,Arthroplasty, Replacement ,Intervertebral Disc ,Low Back Pain ,Intervertebral Disc Displacement ,Follow-Up Studies ,Retrospective Studies - Abstract
To evaluate the mid- or long-term clinical results and the factors that influence the outcomes of prosthetic disc nucleus (PDN) replacement in the treatment of lumbar disc disease.Thirty-four patients who underwent the PDN replacement from March 2002 to October 2003 were followed for an average of 52.6 months (range from 48 to 66 months). Twenty patients were discogenic low back pain, 14 patients were lumbar disc herniation. The follow-up results were evaluated by using the Oswestry disability index (ODI) and the visual analogue scales (VAS) through direct examinations and questionnaires. ODI was 58.4% preoperatively, and VAS was 7.4. Radiography was also used to measure the range of motion (ROM) and disc height of the operative segment, and findings were compared with those on preoperative radiographs.Twelve months after operation, a significant proportion of patients recovered from low back pain or leg pain, ODI decreased to averaged 18.2%. VAS decreased to 1.8, the average increase of the postoperative disc height was 17.6%, ROM was 9.2 degrees. At the final followup, all patients with deteriorated leg radicular symptoms improved, ODI increased from 18.2% 12 months after operation to averaged 31.2%. Low back pain became more serious in 18 patients. VAS increased from 1.8 to 3.1, the average decrease of the postoperative to preoperative disc height was 13.5%, ROM decreased to 6.8 degrees. The rate of degeneration or breakages of the end plates was 64.7% (22/34), implant device migrations were observed in 25 patients.The mid- or long-term outcome of PDN replacement in the treatment of degenerative lumbar disc disease is not as encouraging as that of the short-term follow-up. It is neither effective in term of restoration of the intervertebral disc height nor increase of the ROM of the operative segment, complication rates are significantly higher, and inferior results are to be expected. The selection of suitable surgical candidates and determination of valid indications for operative treatment are very important.
- Published
- 2008
23. Design and Analysis of 2D Photonic Crystal Waveguides for High Coupling Efficiency
- Author
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Ming Wu, Hai Rong Liu, Wei Jun Tong, and De Xiu Huang
- Published
- 2007
24. Structure and Antibacterial Properties of Ag-Doped TiO2 Porous Materials
- Author
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Hai Rong Liu, Yi Lin, Rei Fang Ye, Li Song, and Qi Chen
- Published
- 2007
25. The heredity and control of microstructures of liquid metals during rapid cooling processes
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Jiyong Li, Hai-Rong Liu, and Rang-su Liu
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Liquid metal ,Molecular dynamics ,Materials science ,Icosahedral symmetry ,Chemical physics ,Atom ,Cluster (physics) ,Glass transition ,Microstructure ,Isothermal process - Abstract
An investigation of the heredity and control of the microstructures of liquid metals during rapid cooling processes has been performed under different conditions by molecular dynamics simulations. Some important results have been obtained. Firstly, in the liquid metal system, the choice of which atom becomes the central atom of a small cluster is accidental and random. However, as long as a small cluster has been formed with a given atom as the center and some surrounding atoms, the cluster could be repeated with the same central atom and the same surrounding atoms again and again during the runs. The clusters would possess relative stability during the isothermal processes and heredity (continuity) during the rapid cooling processes. The stability and heredity of icosahedral clusters can be expressed quantitatively by their lifetime or repeatable times. In general, the lifetimes of these clusters increase with decreasing temperature, especially below the glass transition temperature T/sub g/. The number of clusters having a longer lifetime also increases with decreasing temperature. These will give a new way of understanding and controlling the heredity and transition mechanisms of microstructures of liquid and solid metals.
- Published
- 1999
26. Histopathology of melanosis coli and determination of its associated genes by comparative analysis of expression microarrays.
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XIAO-AN LI, YAN ZHOU, SHU-XIAN ZHOU, HAI-RONG LIU, JIN-MEI XU, LONG GAO, XIAN-JING YU, and XIAO-HUI LI
- Subjects
HISTOPATHOLOGY ,MELANOSIS ,GENE expression ,DNA microarrays ,PIGMENTATION disorders - Abstract
Melanosis coli (MC) refers to the condition characterized by abnormal brown or black pigmentation deposits on the colonic mucosa. However, the histopathological findings and genes associated with the pathogenesis of melanosis coli remain to be fully elucidated. The present study aimed to examine the histopathological features and differentially expressed genes of MC. This involved performing hematoxylin and eosin staining, specific staining and immunohistochemistry on tissues sections, which were isolated from patients diagnosed with MC. DNA expression microarray analysis, western blotting and immunofluorescence assays were performed to analyze the differentially expressed genes of melanosis coli. The results demonstrated that the pigment deposits in MC consisted of lipofuscin. A TUNEL assay revealed that a substantial number of apoptotic cells were present within the macrophages and superficial lamina propria of the colonic epithelium. Expression microarray analysis revealed that the significantly downregulated genes were CYP3A4, CYP3A7, UGT2B11 and UGT2B15 in melanosis coli. Western blotting and immunofluorescence assays indicated that the expression of CYP3A4 in the normal tissue was higher than in the MC tissue. The results of the present study provided a comprehensive description of the histopathological characteristics and pathogenesis of MC and for the first time, to the best of our knowledge, demonstrated that the cytochrome P450-associated genes were significantly downregulated in melanosis coli. This novel information can be used to assist in further investigations of melanosis coli. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF
27. A simulation study of microstructure evolution during solidification process of liquid metal Ni
- Author
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Hai-Rong, Liu, primary, Rang-Su, Liu, additional, Ai-Long, Zhang, additional, Zhao-Yang, Hou, additional, Xin, Wang, additional, and Ze-An, Tian, additional
- Published
- 2007
- Full Text
- View/download PDF
28. Mesenchymal stem cell-mediated suppression of hypertrophic scarring is p53 dependent in a rabbit ear model.
- Author
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Yi-Lun Liu, Wei-Hua Liu, Jin Sun, Tuan-Jie Hou, Yue-Ming Liu, Hai-Rong Liu, Yong-Hui Luo, Ning-Ning Zhao, Ying Tang, and Feng-Mei Deng
- Subjects
MESENCHYMAL stem cells ,HYPERTROPHIC scars ,LABORATORY rabbits ,EOSIN ,MESSENGER RNA ,FIBROBLASTS ,NITRIC oxide - Abstract
Introduction Mesenchymal stem cells (MSCs) are considered to play important roles in wound repair and tissue remodeling. Hypertrophic scar (HTS) is a cutaneous condition characterized by deposits of excessive amount of collagen after an acute skin injury. However, currently there is little knowledge about the direct relationship between MSCs and HTS. Methods The hypertrophic scar model was established on rabbit ears. MSCs were isolated from rabbit femur bone marrow and transplanted through ear artery injection. Hypertrophic scar formation was examined using frozen-section analysis, hematoxylin and eosin (HE) staining, Masson's trichrome staining, and scar elevation index. The role of p53 in the MSCs-mediated anti-scarring effect was examined by gene knockdown using p53 shRNA. Results In this study, MSCs engraftment through ear artery injection significantly inhibited the hypertrophic scarring in a rabbit ear hypertrophic scar model, while this anti-scarring function could be abrogated by p53 gene knockdown in MSCs. Additionally, we found that MSCs down-regulated the expression of TGF-β receptor I (TβRI) and alpha-smooth muscle actin (α-SMA) at both mRNA and protein levels in a paracrine manner, and this downregulation was rescued by p53 gene knockdown. Moreover, our results showed that MSCs with p53 gene knockdown promoted the proliferation of fibroblasts through increasing nitric oxide (NO) production. Conclusions These results suggest that MSCs inhibit the formation of HTS in a p53 dependent manner through at least two mechanisms: inhibition of the transformation of HTS fibroblast to myofibroblast; and inhibition of the proliferation of fibroblasts through inhibition of NO production. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
29. Polarization Maintaining Fibre Loop Mirror for NRZ-to-PRZ Conversion in All-Optical Clock Recovery
- Author
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Fan, Xu, primary, Xin-Liang, Zhang, additional, Hai-Rong, Liu, additional, De-Ming, Liu, additional, and De-Xiu, Huang, additional
- Published
- 2006
- Full Text
- View/download PDF
30. Formation and magic number characteristics of clusters formed during solidification processes
- Author
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Hai Rong Liu, Kejun Dong, Ping Peng, Rang Su Liu, Aibing Yu, and Ze An Tian
- Subjects
Molecular dynamics ,Sequence ,Magic number (programming) ,Icosahedral symmetry ,Chemistry ,Group (periodic table) ,Cluster (physics) ,Mineralogy ,General Materials Science ,Condensed Matter Physics ,Microstructure ,Molecular physics ,Index method - Abstract
A molecular dynamics simulation study has been performed for a large-sized system consisting of 10 6 liquid metal Al atoms to investigate the formation and magic number characteristics of various clusters formed during solidification processes. The cluster-type index method (CTIM) is adopted to describe various types of cluster by basic clusters. It is demonstrated that the icosahedral cluster (12 0 12 0) is the most important basic cluster, and that it plays a critical role in the microstructure transition. A new statistical method has been proposed to classify the clusters as some group levels according to the numbers of basic clusters contained in each cluster. The magic numbers can be determined by the respective peak value positions of different group levels of clusters, and the magic number sequence in the system is 13, 19, 25(27), 31(33), 38(40), 42(45), 48(51), 55(59), 61(65), 67 ,... the numbers in the brackets are the second magic number of the corresponding group levels of clusters. This magic number sequence is in good agreement with the experimental results obtained by Schriver and Harris et al, and the experimental results can be reasonably well explained. (Some figures in this article are in colour only in the electronic version)
- Published
- 2007
31. Microstructure Transition of Liquid Metal Al During Heating and Cooling Processes
- Author
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Rang-Su, Liu, primary, Hai-Rong, Liu, additional, Cai-Xing, Zheng, additional, Xiao-Yong, Lu, additional, Ping, Peng, additional, and Ji-Yong, Li, additional
- Published
- 2001
- Full Text
- View/download PDF
32. Effects of high pressure on microstructure evolution and crystallization mechanisms during solidification of nickel.
- Author
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Hai-Tao Zhang, Yun-Fei Mo, Rang-Su Liu, Ze-An Tian, Hai-Rong Liu, Zhao-Yang Hou, Li-Li Zhou, Yong-Chao Liang, and Ping Peng
- Published
- 2018
- Full Text
- View/download PDF
33. Mesenchymal stem cell-mediated suppression of hypertrophic scarring is p53 dependent in a rabbit ear model
- Author
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Tuan-jie Hou, Feng-Mei Deng, Hai-rong Liu, Ning Ning Zhao, Yi-Lun Liu, Ying Tang, Luo Yonghui, Jin Sun, Yueming Liu, and Wei-Hua Liu
- Subjects
Pathology ,medicine.medical_specialty ,Medicine (miscellaneous) ,Biology ,Mesenchymal Stem Cell Transplantation ,Biochemistry, Genetics and Molecular Biology (miscellaneous) ,Masson's trichrome stain ,Paracrine signalling ,Hypertrophic scar ,Cicatrix ,medicine ,Animals ,Fibroblast ,Cells, Cultured ,Skin ,Gene knockdown ,Research ,Mesenchymal stem cell ,Ear ,Mesenchymal Stem Cells ,Cell Biology ,medicine.disease ,Cell biology ,medicine.anatomical_structure ,Molecular Medicine ,Rabbits ,Stem cell ,Tumor Suppressor Protein p53 ,Myofibroblast - Abstract
Introduction Mesenchymal stem cells (MSCs) are considered to play important roles in wound repair and tissue remodeling. Hypertrophic scar (HTS) is a cutaneous condition characterized by deposits of excessive amount of collagen after an acute skin injury. However, currently there is little knowledge about the direct relationship between MSCs and HTS. Methods The hypertrophic scar model was established on rabbit ears. MSCs were isolated from rabbit femur bone marrow and transplanted through ear artery injection. Hypertrophic scar formation was examined using frozen-section analysis, hematoxylin and eosin (HE) staining, Masson’s trichrome staining, and scar elevation index. The role of p53 in the MSCs-mediated anti-scarring effect was examined by gene knockdown using p53 shRNA. Results In this study, MSCs engraftment through ear artery injection significantly inhibited the hypertrophic scarring in a rabbit ear hypertrophic scar model, while this anti-scarring function could be abrogated by p53 gene knockdown in MSCs. Additionally, we found that MSCs down-regulated the expression of TGF-β receptor I (TβRI) and alpha-smooth muscle actin (α-SMA) at both mRNA and protein levels in a paracrine manner, and this down-regulation was rescued by p53 gene knockdown. Moreover, our results showed that MSCs with p53 gene knockdown promoted the proliferation of fibroblasts through increasing nitric oxide (NO) production. Conclusions These results suggest that MSCs inhibit the formation of HTS in a p53 dependent manner through at least two mechanisms: inhibition of the transformation of HTS fibroblast to myofibroblast; and inhibition of the proliferation of fibroblasts through inhibition of NO production.
- Full Text
- View/download PDF
34. The heredity and control of microstructures of liquid metals during rapid cooling processes.
- Author
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Rang-Su Liu, Ji-Yong Li, and Hai-Rong Liu
- Published
- 1999
- Full Text
- View/download PDF
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