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Objective: The objective of the study is to investigate sleep disorders in patients with polycystic ovary syndrome (PCOS) and determine the relationship of sleep disorders with the metabolic and psychogenic aspects of PCOS. Materials and Methods: This case-control study was conducted between October 1, 2019, and March 1, 2020, at the gynaecology and neurology outpatient clinics of a tertiary hospital. The study included 73 patients diagnosed with PCOS and 63 healthy women volunteers. Testosterone, fasting glucose and fasting insulin levels of all the participants were measured. All study participants completed Beck's depression inventory (BDI), Beck's anxiety inventory (BAI), Epworth Sleepiness scale (ESS), Berlin questionnaire (BQ), insomnia severity index (ISI), and Pittsburgh sleep quality index (PSQI). The presence of restless legs syndrome (RLS) was assessed according to the international RLS study group criteria. Results: According to PSQI scores, 61.6% of patients with PCOS and 34.9% of healthy controls had a poor sleep quality (p=0.003). The PCOS group had significantly higher PSQI, ESS, ISI, BAI, BDI, and BQ scores than the control group (p=0.002, p=0.001, p<0.001, p<0.001, p<0.001, p<0.001, respectively). Although 23.3% of patients with PCOS met the RLS criteria, this rate was only 6.3% in the control group (p=0.013). There was a positive correlation between insulin resistance and PSQI (r=0.320, p=0.006). Conclusion: This study's results indicate that PCOS may be a risk factor for several sleep disorders. In addition, the cumulative impact of both the organic and psychogenic changes caused by PCOS may lead to sleep disorders. [ABSTRACT FROM AUTHOR]

The purpose of the study is to evaluate sleep disorders in dysmenorrhea patients and investigate the relationship between sleep disorders and anxiety and depression levels in these patients. This cross-sectional study included 55 primary dysmenorrhea patients who were admitted to the emergency department as well as 47 healthy control subjects. All participants were assessed using Beck Depression Inventory, Beck Anxiety Inventory, Epworth Sleepiness Scale (ESS), Berlin Questionnaire, Insomnia Severity Index (ISI), and Pittsburgh Sleep Quality Index (PSQI). Presence of restless legs syndrome (RLS) was evaluated according to International Restless Legs Syndrome Study Group criteria. Primary dysmenorrhea patients had significantly higher ISI, PSQI overall and ESS scores compared to the control group (p = 0.009, p < 0.001, p = 0.007, respectively). While 20% of primary dysmenorrhea patients met RLS criteria, this rate was 4.3% in the control group (p = 0.017). Sleep quality was significantly correlated with severity of pain, anxiety, and depression in primary dysmenorrhea patients (r = 0.409, p < 0.001; r = 0.527, p < 0.001; r = 0.567, p < 0.001; respectively). This study demonstrates increased rates of sleep disorders in dysmenorrhea patients. Furthermore, our results are indicative that sleep disorders in primary dysmenorrhea patients are induced by both physiological and psychological factors. [ABSTRACT FROM AUTHOR]

Hallervorden-Spatz syndrome is a rare neurodegenerative disease, resulting from mutation in the Pantothenate kinase-2 gene, and characterized by progressive pyramidal and extrapyramidal dysfunction, dementia, retinal degeneration and optic nerve atrophy. Clinical symptoms are related to abnormal iron deposition in the globus pallidus and substantia nigra. We present a case report of a 50-year old woman that was diagnosed as atypical Hallervorden-Spatz disease with dominant extrapyramidal symptoms and the lack of typical eye-of-the-tiger sign in brain MRI. [ABSTRACT FROM AUTHOR]

Objective: This study aims to investigate the relationship between work-related stress and sleep disorders in healthcare personnel working in emergency department and in other departments., Material and Methods: This cross-sectional study included 34 emergency department healthcare personnel (emergency group [EG]) and 35 healthcare personnel working in other departments (non-emergency group [NEG]) and was conducted between November 10, 2019 and March 1, 2020. All participants were administered the following questionnaires: work-related strain inventory (WRSI), Epworth sleepiness scale (ESS), Berlin questionnaire, insomnia severity index (ISI), Pittsburgh sleep quality index (PSQI), Beck depression inventory (BDI), and Beck anxiety inventory (BAI)., Results: While the mean WRSI score of EG was 39.53±7.77, the mean WRSI score of NEG was 30.06±7.26 (t=5.236, p<0.001). According to PSQI, 79.4% of EG and 57.1% of NEG were found to have poor sleep quality (X 2 =3.938, df=1, p =0.047). Median PSQI overall score was 12 (IQR 25th-75th percentiles: 10-14) in EG, and 7 (IQR 25th-75th percentiles: 4-9) in NEG (U=285.5, p <0.001). While the mean anxiety score of EG was 13.35±5.70, the mean anxiety score of NEG was 9.06±6.00 (t=3.046, p =0.003). Median depression score was 12 (IQR 25th-75th percentiles: 10-16) in EG, and was 8 (IQR 25th-75th percentiles: 4-12) in NEG (U=354, p =0.004). A significant positive correlation was found between work-related strain scores and sleep quality, sleepiness, and insomnia severity scores (r=0.541, p <0.001; r=0.310, p =0.010; r=0.357, p =0.004; respectively)., Conclusion: It was determined that healthcare personnel working in the emergency department were at higher risk of developing sleep disorders compared to healthcare personnel working in other departments and that there was a significant relationship between sleep disorders and work-related stress.

Competing Interests: There are no conflicts of interest.