1. ARResT/Interrogate: an interactive immunoprofiler for IG/TR NGS data.
- Author
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Bystry, Vojtech, Reigl, Tomas, Krejci, Adam, Demko, Martin, Hanakova, Barbora, Grioni, Andrea, Knecht, Henrik, Schlitt, Max, Dreger, Peter, Sellner, Leopold, Herrmann, Dietrich, Pingeon, Marine, Boudjoghra, Myriam, Rijntjes, Jos, Pott, Christiane, Langerak, Anton W., Groenen, Patricia J. T. A., Davi, Frederic, Brüggemann, Monika, and Darzentas, Nikos
- Subjects
IMMUNOGLOBULINS ,T cell receptors ,NUCLEOTIDE sequencing ,WEB-based user interfaces ,IMMUNOGENETICS ,STOCHASTIC processes - Abstract
Motivation: The study of immunoglobulins and T cell receptors using next-generation sequencing has finally allowed exploring immune repertoires and responses in their immense variability and complexity. Unsurprisingly, their analysis and interpretation is a highly convoluted task. Results: We thus implemented ARResT/Interrogate, a web-based, interactive application. It can organize and filter large amounts of immunogenetic data by numerous criteria, calculate several relevant statistics, and present results in the form of multiple interconnected visualizations. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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