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I Purpose or Learning Objective: i Primary tumors and tumor-mimicking lesions of the cuboid bone are rarely described in the literature. We also provide a brief overview of diagnosis and management in this largest and only case series on tumor and tumor-mimicking lesions of the cuboid. We describe the primary tumors and tumor mimics that can occur in the cuboid bone and need to be considered when evaluating lesions of the cuboid. [Extracted from the article]