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Previous research on automated guided vehicles (AGVs) and Industry 4.0 has mainly focused on technical aspects, while the humans who work with AGVs as well as the influences on the organisation have received limited attention. This paper aims to explore human- and organisation-related challenges in the introduction of AGVs in production facilities. Two cases are examined and analysed using the Human, Technology, and Organisation (HTO) model, which highlights the interactions between the three subsystems: human, technology, and organisation. The paper shows that several human- and organisation-related challenges arise when introducing AGVs, such as supporting the AGVs with new work procedures for managing AGV errors, determining what different operators need to know about AGVs, and developing acceptance among employees. The identified challenges complement the technical focus in previous research. Actions are proposed to facilitate the introduction of AGVs to avoid or manage the identified challenges. The findings of this study can help managers involved in the introduction of AGVs to consider human- and organisation-related aspects to improve AGV performance and employee well-being. [ABSTRACT FROM AUTHOR]

Dorothy Shepherd (1916–1992), a scholar of Ancient Near Eastern and Islamic art, helped lay the groundwork for scholarship in her field during a period when curatorial work and scholarship was dominated by men. She attended the University of Michigan and after graduation was appointed assistant curator of decoration at the Cooper Union Museum, New York. During World War II Shepherd served in the newly formed Monuments, Fine Arts, and Archives Section of the United States military and in 1947 was appointed associate curator of textiles at the Cleveland Museum of Art (CMA); she retired from the CMA in 1981. During Shepherd's tenure, the CMA acquired textiles and Islamic objects, and organized textile exhibitions showcasing Cleveland's collection; Shepherd also authored numerous publications. In addition, Shepherd produced a significant but as yet unpublished catalog of 280 Islamic textiles in Cleveland's collection. All of this is evidence of a noteworthy career that deserves further study and recognition. [ABSTRACT FROM AUTHOR]

The etiology of severe hemolytic anemia in most patients with recessive hereditary spherocytosis (rHS) and the related disorder hereditary pyropoikilocytosis (HPP) is unknown. Whole-exome sequencing of DNA from probands of 24 rHS or HPP kindreds identified numerous mutations in erythrocyte membrane [alpha]- spectrin (SPTA1). Twenty-eight mutations were novel, with null alleles frequently found in trans to missense mutations. No mutations were identified in a third of SPTA1 alleles (17/48). WGS revealed linkage disequilibrium between the common rHS- linked [[alpha].sup.BH] polymorphism and a rare intron 30 variant in all 17 mutation-negative alleles. In vitro minigene studies and in vivo splicing analyses revealed the intron 30 variant changes a weak alternate branch point (BP) to a strong BP. This change leads to increased utilization of an alternate 3' splice acceptor site, perturbing normal [alpha]-spectrin mRNA splicing and creating an elongated mRNA transcript. In vivo mRNA stability studies revealed the newly created termination codon in the elongated transcript activates nonsense-mediated decay leading to spectrin deficiency. These results demonstrate that a unique mechanism of human genetic disease contributes to the etiology of a third of rHS cases, facilitating diagnosis and treatment of severe anemia and identifying a new target for therapeutic manipulation., Introduction Hereditary spherocytosis (HS), the most common inherited hemolytic anemia in Northern Europeans, affects people of every ethnic background worldwide. A quarter of HS cases exhibit recessive inheritance (rHS) (1-5). [...]

Kitting is a materials-feeding principle commonly used with mixed-model assembly, but literature is lacking with respect to how kit quality can be supported. The purpose of this paper is to create an understanding of the links between kit preparation design aspects and kit preparation error types, that can be useful to support kit quality. The paper draws on empirical data from a multiple case study in the automotive industry to study how typical kit errors are linked to eight kit preparation design aspects: location, work organisation, storage policy, batching policy, storage packaging, kit carrier and container, picking information system, and error communication. The findings suggest several opportunities related to kit preparation design aspects for preventing kit errors and facilitating kit error corrections. The paper extends earlier knowledge and can support kit quality of industrial kit preparation. [ABSTRACT FROM AUTHOR]

A chasm is growing between the advanced technologies available for improving manufacturing operations and those effectively used in practice. The vision of Industry 4.0 is to mobilize industry to seek out these possibilities for improvement and to close the gap between opportunity and reality. However, when compared with more established improvement opportunities such as lean manufacturing, the digitalization of manufacturing lacks in both paradigmatic examples and an understanding of how to achieve the benefits. This lack is a complication of concern: Without an appropriate operations strategy to capture the value of digitalization, manufacturing companies will be unable to focus on technological investments and operational changes. To address this concern, operations management academics must develop new theory through active engagement in the practice of digitalization in manufacturing. This research presents a paradigmatic example, based on engaged scholarship, focused on effectively combining novel object‐interactive and conventional manufacturing syntax for benefiting from digitalization in internal operations and the wider supply chain. The contribution to literature is a novel operations strategy—hybrid digital manufacturing—for capturing the value of Industry 4.0 technologies. [ABSTRACT FROM AUTHOR]

With new market developments and e-commerce, there is an increased use of and interest in automation for order picking. This paper presents a systematic review and content analysis of the literature. It has the purpose of understanding the relevant performance aspects for automated, or partly automated, OPSs and identifying the studied links between design and performance, i.e. identifying which combinations of design aspects and performance aspects have been studied in previous research. For this purpose, 74 papers were selected and reviewed. From the review, it is clear that there has been an increased number of papers dealing with the performance of automated, or partly automated, OPSs in recent years. Moreover, there are differences between the different OPS types, but, overall, the performance categories of throughput, lead time, and operational efficiency have received the most attention in the literature. The paper identifies links between design and performance that have been studied, as well as links that appear to be under-researched. For academics, this paper synthesises the current knowledge on the performance of automation in OPSs and identifies opportunities for future research. For practitioners, the paper provides knowledge that can support the decision-making process of automation in OPSs. [ABSTRACT FROM AUTHOR]

The author examines how the residents of two displaced rural Kansas towns, and their descendants, exhibit a sense of identity common to small farm communities throughout the Great Plains, and how tenacious these ties are even after the physical reminder of their communal bonds no longer exists. By examining the struggles to survive faced by these two towns, Irving and Broughton, the resiliency of the people who called them home, and the continuing expression of community solidarity by the individuals associated with them, the author proposes that the individuals living within these communities created a transcendental identity similar to that of Benedict Anderson's "Imagined Communities." This communal identity remains a unifying bond without the need for an enduring physical signifier.