25 results on '"Harnor, Suzannah J."'
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2. Targeting DNA-PK as a Therapeutic Approach in Oncology
3. Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4
4. Modulation of ERK5 Activity as a Therapeutic Anti-Cancer Strategy
5. Parallel Optimization of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Kinase Domain Inhibitor
6. Advanced approaches of developing targeted covalent drugs
7. An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)
8. Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction
9. 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase
10. Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation
11. Advanced approaches of developing targeted covalent drugs
12. Human Toxicity Caused by Indole and Indazole Carboxylate Synthetic Cannabinoid Receptor Agonists: From Horizon Scanning to Notification
13. Targeting DNA‐Dependent Protein Kinase for Cancer Therapy
14. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines
15. Inhibition of the DNA-Dependent Protein Kinase for Cancer Therapy
16. 2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinaseElectronic supplementary information (ESI) available: Kinase profiling, assay details, synthetic procedures and characterisation data for all compounds; including aniline precursors. All cell lines were supplied by the American Type Culture Collection, Manassas, Virginia, United States. All animal experiments performed were conducted under a UK Government Home Office License in accordance with relevant national laws. All procedures were reviewed and approved by the Newcastle University Animal Welfare Ethical Board and performed according to institutional guidelines. See DOI: 10.1039/d0md00074d
17. Concise syntheses of bridged morpholines
18. Abstract 5451: Profiling inhibitors of MDM2:p53 and MDMX:p53 in relation to MDMX protein levels
19. Synthesis of 3′-deoxy-3′-fluorothymidine (FLT) 5′-O-glucuronide: a reference standard for imaging studies with [18F]FLT
20. The Enhanced In Vivo Activity of the Combination of a MEK and a PI3K Inhibitor Correlates with [18F]-FLT PET in Human Colorectal Cancer Xenograft Tumour-Bearing Mice
21. ChemInform Abstract: Photochemical Synthesis of Benz[h]isoquinolines.
22. Photochemical synthesis of benz[h]isoquinolines
23. Synthesis of 3′-deoxy-3′-fluorothymidine (FLT) 5′-O-glucuronide: a reference standard for imaging studies with [18F]FLT.
24. The Enhanced In Vivo Activity of the Combination of a MEK and a PI3K Inhibitor Correlates with [18F]-FLT PET in Human Colorectal Cancer Xenograft Tumour-Bearing Mice.
25. An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.
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