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9 results on '"Harrington, Lacey"'

7. Non-hemolytic α-AApeptides as antimicrobial peptidomimetics

Author

Padhee, Shruti, primary, Hu, Yaogang, additional, Niu, Youhong, additional, Bai, Ge, additional, Wu, Haifan, additional, Costanza, Frankie, additional, West, Leigh, additional, Harrington, Lacey, additional, Shaw, Lindsey N., additional, Cao, Chuanhai, additional, and Cai, Jianfeng, additional

Published
2011
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9. Therapy-related B lymphoblastic leukemia with t(4;11)(q21;q23)/AF4-MLL in a patient with mantle cell lymphoma after recent aggressive chemotherapy: a unique case report.

Author

Holdener SL, Harrington L, Nguyen J, Horna P, Sagatys E, Shah B, and Zhang L

Subjects
Cyclin D1 genetics, Drug Therapy, Drug-Related Side Effects and Adverse Reactions complications, Gene Rearrangement, Histone-Lysine N-Methyltransferase, Humans, Immunoglobulin Heavy Chains genetics, Male, Middle Aged, Transcriptional Elongation Factors, Treatment Outcome, Chromosomes, Human, Pair 11 genetics, Chromosomes, Human, Pair 4 genetics, DNA-Binding Proteins genetics, Lymphoma, Mantle-Cell drug therapy, Myeloid-Lymphoid Leukemia Protein genetics, Nuclear Proteins genetics, Precursor Cell Lymphoblastic Leukemia-Lymphoma etiology, Precursor Cell Lymphoblastic Leukemia-Lymphoma genetics, Translocation, Genetic genetics
Abstract

Mantle cell lymphoma (MCL) is a mature B-cell lymphoma associated with the hallmark translocation t(11;14)(q13;32), which involves the cyclin D1 (CCND1) and immunoglobin heavy chain (IgH) genes. It may transform to a more aggressive blastoid or pleomorphic variant, with or without acquisition of chromosomal abnormalities. MCL could also present with a leukemic phase with marked lymphocytosis. A literature search did not reveal any prior reports of MCL transforming to or followed by a B-cell lymphoblastic leukemia (B-ALL).

Published
2014

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