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2. HUNGER GAMES: ILLIUSTRATION BY HIT AND RUN: DELIVERY APPS THAT TURNED ORDERING IN INTO THE NEW DINING OUT ARE FORCING LA. RESTAURANTS TO COOK UP A NEW PARADIGM OR RISK STARVATION

Author

Harrington, Maureen

Subjects
Family-owned businesses, Starvation, Restaurants, Time, Pizza, Travel, recreation and leisure
Abstract

CANTER'S IS THE Dodger Stadium of delis. The enormous menu; the nearly 24-hour service; the Kibitz Room, home to generations of rock and rollers and late-night rabble-rousers--none of it has [...]

Published
2020

3. The Virtual Dental Home: Implications for Policy and Strategy

Author

Glassman, Paul, Harrington, Maureen, Mertz, Elizabeth, and Namakian, Maysa

Subjects
Biomedical and Clinical Sciences, Dentistry, Clinical Research, Health Services, Behavioral and Social Science, Prevention, Dental/Oral and Craniofacial Disease, Health and social care services research, 8.1 Organisation and delivery of services, Oral and gastrointestinal, Good Health and Well Being, California, Delivery of Health Care, Dental Auxiliaries, Dental Care, Dental Care for Disabled, Electronic Health Records, Health Planning, Health Policy, Health Services Accessibility, Humans, Poverty, Practice Management, Dental, Remuneration, Telemedicine, United States, User-Computer Interface, Vulnerable Populations, Workforce
Abstract

Widely recognized problems with the U.S. health care system, including rapidly increasing costs and disparities in access and outcomes also exist in oral health. If oral health systems are to meet the "Triple Aim" of improving the experience of care, improving the health of populations, and reducing per capita costs of health care, new and innovative strategies will be needed including new regulatory, delivery, and financing systems. The virtual dental home is one such system.

Published
2012

5. Family Leisure

Author

Harrington, Maureen, Rojek, Chris, editor, Shaw, Susan M., editor, and Veal, A. J., editor

Published
2006
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11. Tinsel Town: WE SCOURED THE CITY, NOT ONCE BUT TWICE, AND FOUND PERFECT GIFTS FOR THOSE NAUGHTY AND NICE.

Author

GINSBERG, MERLE, HARRINGTON, MAUREEN, NICHOLS, CHRIS, PLATT, HEATHER, and SLENSKE, MICHAEL

Subjects
EARRINGS, INTERIOR decoration, STONE
Abstract

The article offers brief information on holiday gifts including the Andy Warhol limited-edition ornaments from Tiffany & Co., the Gregory Parkinson Surround napkins from Kneeland Co., and the Herend blue peony ginger jar from Geary's.

Published
2022

12. Transient membrane recruitment of IRAK-1 in response to LPS and IL-1 [beta] requires TNF R1

Author

Lockett, Angelia, Goebl, Mark G., and Harrington, Maureen A.

Subjects
Ubiquitin -- Properties, Phosphorylation -- Evaluation, Tumor necrosis factor -- Properties, Polysaccharides -- Properties, Cytokines -- Properties, Physiological research, Biological sciences
Abstract

The transcription factor NF-KB is an essential regulator of the innate immune response that functions as the first line of defense against infections. Activation of the innate immune response by bacterial lipopolysaccharide (LPS) triggers production of tumor necrosis factor-[alpha] (TNF-[alpha]) followed by interleukin-1 (IL-I). The IL-1 receptor associated kinase-1 (IRAK-1) is an integral component of the LPS, TNF-[alpha], and IL-1 signaling pathways that regulate NF-[kappa]B. Thus we hypothesized that IRAK-I coordinates cellular NF-[kappa]B responses to LPS, TNF-[alpha], and IL-1. In contrast to TNF-[alpha] where IRAK-1 subcellular localization does not change, treatment with LPS or IL-1 leads to a loss in cytoplasmic IRAK-1 with a coordinate increase in plasma membrane associated modified IRAK-1. In fibroblasts lacking the type 1 TNF-[alpha] receptor (TNF R 1), IRAK- 1 turnover is altered and modification of IRAK- 1 in the plasma membrane is decreased in response to LPS and IL-1, respectively. When NF-[kappa]B controlled gene expression is measured, fibroblasts lacking TNF R1 are hyper-responsive to LPS, whereas a more variable response to IL-1 is seen. Further analysis of the LPS response revealed that plasma membrane-associated IRAK-1 is found in Toll 4, IL-1, and TNF R1-containing complexes. The data presented herein suggest a model whereby the TNF R1-IRAK-1 interaction integrates the cellular response to LPS, TNF-[alpha], and IL-1, culminating in a cell poised to activate TNF-[alpha]-dependent NF-[kappa]B controlled gene expression. In the absence of TNF Rl-dependent events, exposure to LPS or IL-1 leads to hyperactivation of the inflammatory response. TNF-[alpha]; cytokines; ubiquitinylation; cytoplasmic; phosphorylation

Published
2008

13. Phosphorylation of SIMPL modulates RelA-associated NF-[kappa]B-dependent transcription

Author

Luo, Yong, Kwon, Hyung-Joo, Montano, Sherwin, Georgiadis, Millie, Goebl, Mark G., and Harrington, Maureen A.

Subjects
Inflammation -- Research, Phosphorylation -- Analysis, Cytokines -- Research, Biological sciences
Abstract

Epidemiological data have implicated perturbations in the regulation of NF-[kappa]B activity to diseases that affect a large number of Americans today. Specifically, chronic activation of genes involved in the inflammatory response is associated with the progression of and complications in diabetes, arthritis, atherosclerosis, and cancer. Insight into the mechanisms governing the regulation of NF-[kappa]B transcriptional activity will provide the molecular link between NF-[kappa]B and these pathological states. SIMPL (signaling molecule that associates with mouse Pelle-like kinase) is a component of a signaling pathway through which tumor necrosis factor-[alpha] (TNF-[alpha]) induces NF-[kappa]B-controlled gene transcription. SIMPL interacts with the nuclear pool of the NF-[kappa]B subunit, p65, in a TNF-[alpha]-dependent manner to enhance p65-dependent gene transcription. How SIMPL activity is regulated is unknown. Under basal as well as TNF-[alpha]-stimulated conditions, SIMPL phosphopeptides were identified. SIMPL mutants lacking sites that are phosphorylated under basal conditions diminished p65 transactivation activity but had no effect on SIMPL nuclear localization. SIMPL mutants lacking sites of TNF-[alpha]-enhanced phosphorylation impaired nuclear localization and prevented TNF-[alpha]-induced p65 transactivation activity. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 coactivator function of SIMPL. cytokines; inflammation; signal transduction; nuclear factor-[kappa]B

Published
2007

15. Autoignition Chamber for Remote Testing of Pyrotechnic Devices

Author

Harrington, Maureen L, Steward, Gerald R, and Dartez, Toby W

Subjects
Technology Utilization And Surface Transportation
Abstract

The autoignition chamber (AIC) performs by remotely heating pyrotechnic devices that can fit the inner diameter of the tube furnace. Two methods, a cold start or a hot start, can be used with this device in autoignition testing of pyrotechnics. A cold start means extending a pyrotechnic device into the cold autoignition chamber and then heating the device until autoignition occurs. A hot start means heating the autoignition chamber to a specified temperature, and then extending the device into a hot autoignition chamber until autoignition occurs. Personnel are remote from the chamber during the extension into the hot chamber. The autoignition chamber, a commercially produced tubular furnace, has a 230-V, single-phase, 60-Hz electrical supply, with a total power output of 2,400 W. It has a 6-in. (15.2-cm) inner diameter, a 12-in. (30.4-cm) outer diameter and a 12-in.- long (30.4-cm), single-zone, solid tubular furnace (element) capable of heating to temperatures up to 2,012 F (1,100 C) in air.

Published
2009

22. Malibu beach inn's quiet post-Geffen glitz: purchased by the Mani brothers for $80 million from The Operator himself, the town's only luxury hotel (for now) debuts with a refresh by Waldo Fernandez, an ocean view from every room and an ongoing role as the 1-percenters' local guesthouse

Author

Harrington, Maureen

Subjects
Hotels and motels -- Marketing -- Management -- United States, Company marketing practices, Company business management, Arts and entertainment industries, Business, Business, international
Abstract

First-time malibu visitors who expect a Cali version of the Cote d'Azur are in for a surprise. Where are the chic cafes and 'models' parading in bikinis and diamonds? Not [...]

Published
2016

23. HUNGER GAMES.

Author

HARRINGTON, MAUREEN

Abstract

The article offers information related to family's landmark on Fairfax Avenue in Los Angeles, California. Topics include the views of manager, Lupe Gomez, on the same; and revenue from deliveries not bolster margins enough to offset the expense of running a delivery service on top of the day-to-day costs of a dining room and kitchen.

Published
2020

24. THE CRISIS OF FOSTER CARE.

Author

Roche, Timothy, August, Melissa, Grace, Julie, Harrington, Maureen, Hylton, Hilary, Monroe, Sylvester, and Willwerth, James

Subjects
FOSTER home care, FOSTER children, CHILD abuse, INSTITUTIONAL care of children
Abstract

Addresses problems with the foster care system in the United States. Incidents of children dying due to poor treatment by foster parents; Thoughts on the reason why there are problems with the system; Examples of foster children who have been abused and rebelled as a result of being through the system. INSETS: Fifteen Years in Foster..., by Timothy Roche and Sylvester...;Is Adoption the Solution? by Timothy Roche et al.

Published
2000

26. The Victims: Never Again.

Author

Goldstein, Andrew, Harrington, Maureen, and Woodbury, Richard

Subjects
CRIME victims, SCHOOL shootings, STUDENTS, ATTITUDE (Psychology)
Abstract

Focuses on victims of the 1999 shooting at Columbine High School in Littleton, Colorado. Why the families of victims refuse to be overwhelmed by feelings of rage; Details of rehabilitation efforts of survivors; Comments of students.

Published
1999

27. The Columbine Tapes.

Author

Gibbs, Nancy, Roche, Timothy, Goldstein, Andrew, Harrington, Maureen, and Woodbury, Richard

Subjects
SCHOOL shootings, SCHOOL violence, STUDENTS
Abstract

Focuses on the contents of five videocassettes in which Dylan Klebold and Eric Harris, the gunmen in the 1999 Columbine High School shooting reveal their motives. Why Klebold and Harris said their parents could not have stopped them; Opinions of the gunmen on fellow classmates at the Littleton, Colorado school; Views of policemen, investigators, and school principal Frank DeAngelis. INSETS: Could He Have Done More?, by J. Cloud et al;Some Kids Are Orchids, by James Garbarino.

Published
1999

28. Simply Grand.

Author

Rutherford, Megan, DeQuine, Jeanne, Harrington, Maureen, Moffett, Anne, Narayan, Chandrika, and Navon, Adrianne

Subjects
GRANDPARENTS, GRANDPARENTING, PARENT-child relationships, INTERGENERATIONAL relations, FAMILIES
Abstract

Focuses on the important role of grandparenting. Intergenerational ties that give a child the sense of tradition and unconditional love; Use of family sites on the Web; Challenge of uniting children with grandparents who are separated by culture or distance; Intergenerational programs launched by travel agents and Elderhostel.

Published
1999

29. Inside the Crazy Culture of Kids Sports.

Author

Ferguson, Andrew, Liss, Steve, Dowell, William, Drummond, Tamala, Grace, Julie, Harrington, Maureen, Monroe, Sylvester, and Shannon, Elaine

Subjects
RECREATION -- Social aspects, CHILDREN'S health, ATHLETICS -- Social aspects, PARENT-child relationships & society
Abstract

Examines the high number of children involved in athletics in the United States. Busyness of children's sports schedules; Participation in multiple sports and teams at one time; Rising expectations in athletics for children; Recruitment by children's coaches; Goals of participation, including scholarships; Benefits of participating in sports; Time and expense involved; Concept of fun and unstructured play; Influence of parents upon children's performance; Critics of those who overparticipate. INSET: Poor Kids Need a Sporting Chance, Ron Stodghill II.

Published
1999

30. Portrait of a Deadly Bond.

Author

Pooley, Eric, Cloud, John, Gwynne, S.C., Harrington, Maureen, Shapiro, Jeffrey, Rivera, Elaine, and Woodbury, Richard

Subjects
SCHOOL violence, JUVENILE homicide
Abstract

Profiles Eric Harris and Dylan Klebold, murderers in the Littleton, Colorado, school shootings. Relations of Harris with student Brooks Brown; Possible accomplices in the crime; Speculation about their motives; Their group, called the Trench Coat Mafia; Influence of athletes and cheerleaders at Columbine High School in Littleton; Plotting the shootings; Harris' web site; Harris rejected by the Marines. INSETS: Battling the Columbine Copycats, by Tammerlin Drummond;After the Grief: The Lawyers, by Adam Cohen, Richard Woodbury;Drop the Stigma, by Tipper Gore.

Published
1999

31. On March 4, Eric Harris and Dylan Klebold sat for this class picture. On April 17, they both went to the prom. What they did next left their school......in sorrow and disbelief.

Author

Gibbs, Nancy, Grace, Julie, Gwynne, S.C., Harrington, Maureen, Jackson, David S., Shapiro, Jeffrey, and Woodbury, Richard

Subjects
SCHOOL violence, JUVENILE homicide, COLUMBINE High School Massacre, Littleton, Colo., 1999, CRIMES against students, MASSACRES
Abstract

Discusses the massacre at Columbine High School in Littleton, Colorado. Murder of 15 people by Dylan Klebold and Eric Harris; How the slaughter has opened a sad national conversation about what turned two boys into mass murderers; Details of the events, which took place on Adolf Hitler's birthday; The group, the Trench Coat Mafia, which embraced Nazi mythology; Rivalry between the Trench Coats and athletes; Agony of parents waiting for news of their children; The search for an explanation.

Published
1999

32. Do Computers Really Save Money?

Author

Church, George J., Cray, Dan, Dowell, William, Harrington, Maureen, Hequet, Marc, and Roche, Timothy

Subjects
COMPUTER systems management, COMPUTERS, LABOR productivity, INDUSTRIAL efficiency, MEASUREMENT, ECONOMICS
Abstract

Examines the extent to which computerization improves efficiency. Example of new computers for New York Presbyterian Health Care; Labor and the impact of computers on the United States economy; Business implications of these issues; Ways computers improve life; Troubles quantifying computers' benefits; Four goals executives have for their investments in computer power; Undermeasuring productivity gains; Other reasons to computerize.

Published
1998

33. The fun is back.

Author

Stein, Joel, Cray, Dan, Harrington, Maureen, Kramer, Staci D., and Ratnesar, Romesh

Subjects
HOME runs (Baseball)
Abstract

Describes the efforts of baseball players Mark McGwire and Ken Griffey, Jr., to break Roger Maris' record for number of home runs in a season. How baseball has saved itself; Contributions of McGwire, Griffey, and other stars; Details about McGwire and Griffey's backgrounds and playing styles.

Published
1998

38. Properties of Double-Stranded Oligonucleotides Modified with Lipophilic Substituents

Author

Laing, Brian M, Barrow-Laing, Lisa, Harrington, Maureen, Long, Eric C, Bergstrom, Donald E, Laing, Brian M, Barrow-Laing, Lisa, Harrington, Maureen, Long, Eric C, and Bergstrom, Donald E

Abstract

We have synthesized a series of short, self-complementary oligonucleotide sequences modified at their 5'- and/or 3'- termini with a lipophilic dodecane (C 12); these systems serve as models to assess the biophysical properties of double-stranded DNA (dsDNA) equipped with potentially stabilizing lipophilic substituents. Addition of C12 to the 5'-termini of self-complementary 10 nucleotide sequences increased their duplex melting temperatures (T,) by similar to 4-8 degrees C over their corresponding unmodified sequences. C12 functionalities added to both the 3'- and 5'-termini increased T-m values by similar to 10-12 degrees C. The observed increases in T-m correlated with greater duplex stabilities as determined by the free energy values (Delta G) derived from T-m plots. There is a greater degree of stabilization when C12 is positioned with a C.G base pair at the termini, and the stabilizing effect of lipophilic groups far exceeds the effect seen in adding an additional base pair to both ends of DNA. Stable, short dsDNA sequences are of potential interest in the development of transcription factor decoy oligonucleotides as possible therapeutic agents and/or biological tools. These results suggest that the stability of short dsDNA sequences are improved by lipophilic substituents and can be used as the basis for the design of dsDNAs with improved biological stabilities and function under physiological conditions.

Published
2010

39. Countries bring trade into development projects: countries are putting priority on trade-related assistance in this new model for financing development projects, by the Millennium Challenge Corporation

Author

Harrington, Maureen

Subjects
Millennium Challenge Corp. -- Finance, Economic assistance, Business, Economics, Business, international, Company financing, Finance, International trade
Abstract

Benin: rehabilitating the port of Cotonou. Ghana: building packing and storage facilities for export crops. Madagascar: identifying international market opportunities for small businesses. Each of these foreign aid projects was [...]

Published
2007

45. Tumor Necrosis Factor-α- and Interleukin-1-Induced Cellular Responses: Coupling Proteomic and Genomic Information

Author

Ott, Lee W., primary, Resing, Katheryn A., additional, Sizemore, Alecia W., additional, Heyen, Joshua W., additional, Cocklin, Ross R., additional, Pedrick, Nathan M., additional, Woods, H. Cary, additional, Chen, Jake Y., additional, Goebl, Mark G., additional, Witzmann, Frank A., additional, and Harrington, Maureen A., additional

Published
2011
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49. To Be Young and Gay in Wyoming.

Author

Lopez, Steve, Harrington, Maureen, and Woodbury, Richard

Subjects
HOMOSEXUALITY & society, GAY college students, DEATH, CRIMES against gay people, SOCIAL history
Abstract

Describes challenges faced by homosexuals in Wyoming. Murder of gay college student Matthew Shepard in Laramie; How many in Wyoming view gays; Shepard's background and lifestyle; Views of homosexual Jeff Korhonen about gay life in Wyoming; Murder allegedly committed by Aaron McKinney and Russell Henderson; Assertions of homophobia in the Wyoming legislature; Shepard's burial.

Published
1998

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