35 results on '"Harris, Georgianna"'
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2. Identification and Selective Inhibition of an Isozyme of Steroid 5α- Reductase in Human Scalp
3. Discovery of betamethasone 17α-carbamates as dissociated glucocorticoid receptor modulators in the rat
4. Modeling aided design of potent glycogen phosphorylase inhibitors
5. Mechanism-based inhibition of human steroid five-alpha-reductase by finasteride: enzyme-catalyzed formation of NADP-dihydrofinasteride, a potent bisubstrate analog inhibitor
6. Identification and selective inhibition of an isozyme of steroid 5-alpha-reductase in human scalp
7. Colorimetric Detection of Glutamine Synthetase-Catalyzed Transferase Activity in Glucocorticoid-Treated Skeletal Muscle Cells
8. Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: Synthesis, in vitro profile, molecular modeling studies, and in vivo experiments
9. Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity
10. Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy
11. Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism
12. Novel N-Arylpyrazolo[3,2-c]-Based Ligands for the Glucocorticoid Receptor: Receptor Binding and in Vivo Activity
13. Novel 3,4‐Dihydroquinolin‐2(1H)‐one Inhibitors of Human Glycogen Phosphorylase a.
14. Skeletal muscle: a dual system to measure glucocorticoid-dependent transactivation and transrepression of gene regulation
15. Glucose-Lowering in a db/db Mouse Model by Dihydropyridine Diacid Glycogen Phosphorylase Inhibitors.
16. Novel 3,4-Dihydroquinolin-2(1 H )-one inhibitors of human glycogen phosphorylase a
17. A new class of glycogen phosphorylase inhibitors
18. Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors
19. Novel Pyrazolo[3,4-d]pyrimidine-Based Inhibitors of Staphlococcus aureus DNA Polymerase III: Design, Synthesis, and Biological Evaluation
20. Allosteric Effects of Dexamethasone and RU486 on Glucocorticoid Receptor-DNA Interactions
21. Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III
22. Steroid 5α-reductase inhibitors in androgen-dependent disorders
23. 4-Methyl-3-oxo-4-aza-5α-androst-1-ene-17β-N-aryl-carboxamides: an approach to combined androgen blockade [5α-reductase inhibition with androgen receptor binding in vitro]
24. Steroid 5α-Reductase: Comparative Study of Mechanism of Inhibition by Nonsteroids ONO-3805 and LY191704
25. 4-Aza-3-oxo-5α-androst-1-ene-17β-N-arylcarboxamides as Dual Inhibitors of Human Type 1 and Type 2 Steroid 5α-Reductases. Dramatic Effect of N-Aryl Substituents on Type 1 and Type 2 5α-Reductase Inhibitory Potency
26. Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
27. 4-Aza-3-oxo-5.alpha.-androst-1-ene-17.beta.-N-arylcarboxamides as Dual Inhibitors of Human Type 1 and Type 2 Steroid 5.alpha.-Reductases. Dramatic Effect of N-Aryl Substituents on Type 1 and Type 2 5.alpha.-Reductase Inhibitory Potency
28. Activity of the Type 1 5α-Reductase Exhibits Regional Differences in Isolated Sebaceous Glands and Whole Skin
29. 4-AZASTEROIDS AS 5α-REDUCTASE INHIBITORS: IDENTIFICATION OF 4,7β-DIMETHYL-4-AZA-5α-CHOLESTAN-3-ONE (MK-386) AS A SCALP ISOZYME SELECTIVE INHIBITOR
30. 4,7.beta.-Dimethyl-4-azacholestan-3-one (MK-386) and Related 4-Azasteroids as Selective Inhibitors of Human Type 1 5.alpha.-Reductase
31. Novel 3,4-Dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a
32. Inactivation of the ribonucleoside triphosphate reductase from Lactobacillus leichmannii by 2'-chloro-2'-deoxyuridine 5'-triphosphate: a 3'-2' hydrogen transfer during the formation of 3'-keto-2'-deoxyuridine 5'-triphosphate
33. 2'-Deoxy-2'-halonucleotides as alternate substrates and mechanism-based inactivators of Lactobacillus leichmannii ribonucleotide reductase
34. Inactivation of the Lactobacillus leichmannii ribonucleoside triphosphate reductase by 2'-chloro-2'-deoxyuridine 5'-triphosphate: stoichiometry of inactivation, site of inactivation, and mechanism of the protein chromophore formation
35. Enzymatic preparation of high-specific-activity β-d-[6,6′-3H]fructose-2,6-bisphosphate: Application to a sensitive assay for fructose-2,6-bisphosphatase
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