474 results on '"Harris, Ross"'
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2. Hospitalisation risk for COVID-19 patients infected with SARS-CoV-2 variant B.1.1.7: cohort analysis
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Nyberg, Tommy, Twohig, Katherine A., Harris, Ross J., Seaman, Shaun R., Flannagan, Joe, Allen, Hester, Charlett, Andre, De Angelis, Daniela, Dabrera, Gavin, and Presanis, Anne M.
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Statistics - Applications ,Quantitative Biology - Populations and Evolution - Abstract
Objective: To evaluate the relationship between coronavirus disease 2019 (COVID-19) diagnosis with SARS-CoV-2 variant B.1.1.7 (also known as Variant of Concern 202012/01) and the risk of hospitalisation compared to diagnosis with wildtype SARS-CoV-2 variants. Design: Retrospective cohort, analysed using stratified Cox regression. Setting: Community-based SARS-CoV-2 testing in England, individually linked with hospitalisation data. Participants: 839,278 laboratory-confirmed COVID-19 patients, of whom 36,233 had been hospitalised within 14 days, tested between 23rd November 2020 and 31st January 2021 and analysed at a laboratory with an available TaqPath assay that enables assessment of S-gene target failure (SGTF). SGTF is a proxy test for the B.1.1.7 variant. Patient data were stratified by age, sex, ethnicity, deprivation, region of residence, and date of positive test. Main outcome measures: Hospitalisation between 1 and 14 days after the first positive SARS-CoV-2 test. Results: 27,710 of 592,409 SGTF patients (4.7%) and 8,523 of 246,869 non-SGTF patients (3.5%) had been hospitalised within 1-14 days. The stratum-adjusted hazard ratio (HR) of hospitalisation was 1.52 (95% confidence interval [CI] 1.47 to 1.57) for COVID-19 patients infected with SGTF variants, compared to those infected with non-SGTF variants. The effect was modified by age (P<0.001), with HRs of 0.93-1.21 for SGTF compared to non-SGTF patients below age 20 years, 1.29 in those aged 20-29, and 1.45-1.65 in age groups 30 years or older. Conclusions: The results suggest that the risk of hospitalisation is higher for individuals infected with the B.1.1.7 variant compared to wildtype SARS-CoV-2, likely reflecting a more severe disease. The higher severity may be specific to adults above the age of 30., Comment: 29 pages, 9 figures
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- 2021
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3. Effects of Second Dose of SARS-CoV-2 Vaccination on Household Transmission, England
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Zaidi, Asad, Harris, Ross, Hall, Jennifer, Woodhall, Sarah, Andrews, Nick, Dunbar, Kevin, Lopez-Bernal, Jamie, and Dabrera, Gavin
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England -- Health aspects ,Households -- Statistics -- Health aspects ,Disease transmission -- Statistics -- Risk factors -- Control ,Health - Abstract
Observational studies conducted in several countries including Qatar (1) and the United Kingdom (2) have demonstrated that SARS-CoV-2 vaccination provides protection against symptomatic infection, hospitalization, and death. The role of [...]
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- 2023
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4. Implications for HIV elimination by 2030 of recent trends in undiagnosed infection in England: an evidence synthesis
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Presanis, Anne M, Kirwan, Peter, Miltz, Ada, Croxford, Sara, Harris, Ross, Heinsbroek, Ellen, Jackson, Chris, Mohammed, Hamish, Brown, Alison, Delpech, Valerie, Gill, O Noel, and De Angelis, Daniela
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Statistics - Applications - Abstract
A target to eliminate Human Immuno-deficiency Virus (HIV) transmission in England by 2030 was set in early 2019. Estimates of recent trends in HIV prevalence, particularly the number of people living with undiagnosed HIV, by exposure group, ethnicity, gender, age group and region, are essential to monitor progress towards elimination. A Bayesian synthesis of evidence from multiple surveillance, demographic and survey datasets relevant to HIV in England is employed to estimate trends in: the number of people living with HIV (PLWH); the proportion of these people unaware of their HIV infection; and the corresponding prevalence of undiagnosed HIV. All estimates are stratified by exposure group, ethnicity, gender, age group (15-34, 35-44, 45-59, 60-74), region (London, outside London) and year (2012-2017). The total number of PLWH aged 15-74 in England increased from 82,400 (95% credible interval, CrI, 78,700 to 89,100) in 2012 to 89,500 (95% CrI 87,400 to 93,300) in 2017. The proportion diagnosed steadily increased from 84% (95% CrI 77 to 88%) to 92% (95% CrI 89 to 94%) over the same time period, corresponding to a halving in the number of undiagnosed infections from 13,500 (95% CrI 9,800 to 20,200) to 6,900 (95% CrI 4,900 to 10,700). This decrease is equivalent to a halving in prevalence of undiagnosed infection and is reflected in all sub-groups of gay, bisexual and other men who have sex with men and most sub-groups of black African heterosexuals. However, decreases were not detected for some sub-groups of other ethnicity heterosexuals, particularly outside London. In 2016, the Joint United Nations Programme on HIV/ AIDS target of diagnosing 90% of people living with HIV was reached in England. To achieve HIV elimination by 2030, current testing efforts should be enhanced to address the numbers of heterosexuals living with undiagnosed HIV, especially outside London.
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- 2019
5. Inspection models for automotive parts remanufacture
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Harris, Ross Stephen, Windmill, James, and Ijomah, Winifred
- Abstract
Remanufacturing can be classed as the act of bringing end-of-use products back to "like new" conditions with warranty to match. The field has been steadily growing in recent years due to a cultural shift towards sustainable practices. 'Inspection' is the action of assessing parts in order to determine the needed actions to bring them back to standard, and is a critical factor. Previous work by Errington and Ridley in this area have shown the necessity of increased structure and tools to aid automotive remanufacturing inspection. This aim of this research was to investigate the inspection issues faced by automotive parts remanufacturers within the UK and develop tools to alleviate the lack of guidance on inspection activities. Case study methods were used at five different companies to identify the issues, this included over-reliance on inspector expertise, difficulties in knowledge share, and an aging workforce. A 4-part model was developed to combat these issues, and was later validated through both industry and academic review, and an expert panel to ensure robustness and rjgour. This research was unique in that it approached inspection by focusing on the practices and methods rather than a business or strategic perspective targeting cost effectiveness rather than operational efficacy. The beneficiaries of this research include academia and industry, with academia furthering the building of benchmarking for inspection, and a new method of investigating inspection within remanufacturing. Industry can use this research to further refine their inspection practices and in training with new staff.
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- 2020
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6. Fluoroquinolones and isoniazid-resistant tuberculosis: implications for the 2018 WHO guidance
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Stagg, Helen R, Bothamley, Graham H, Davidson, Jennifer A, Kunst, Heinke, Lalor, Maeve K, Lipman, Marc C, Loutet, Miranda G, Lozewicz, Stefan, Mohiyuddin, Tehreem, Abbara, Aula, Alexander, Eliza, Booth, Helen, Creer, Dean D, Harris, Ross J, Kon, Onn Min, Loebinger, Michael R, McHugh, Timothy D, Milburn, Heather J, Palchaudhuri, Paramita, Phillips, Patrick PJ, Schmok, Erik, Taylor, Lucy, Abubakar, Ibrahim, Baker, Lucy V, Barrett, Jessica C, Burgess, Helen, Cosgrove, Catherine, Dunleavy, Anne, Francis, Marie, Gupta, Urmi, Hamid, Shahid, Haselden, Brigitte M, Holden, Emma, Kahr, Vanessa, Lynn, William, Perrin, Felicity M, Rahman, Ananna, and Soobratty, Mohammad R
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Biomedical and Clinical Sciences ,Clinical Sciences ,Tuberculosis ,Rare Diseases ,Antimicrobial Resistance ,Clinical Research ,Infectious Diseases ,Orphan Drug ,Infection ,Good Health and Well Being ,Adolescent ,Adult ,Aged ,Antitubercular Agents ,Drug Therapy ,Combination ,Duration of Therapy ,Ethambutol ,Female ,Fluoroquinolones ,Humans ,Isoniazid ,Levofloxacin ,Logistic Models ,London ,Male ,Middle Aged ,Practice Guidelines as Topic ,Pyrazinamide ,Recurrence ,Retrospective Studies ,Rifampin ,Treatment Failure ,Tuberculosis ,Multidrug-Resistant ,World Health Organization ,Young Adult ,London INH-R TB study group ,Medical and Health Sciences ,Respiratory System ,Cardiovascular medicine and haematology - Abstract
2018 World Health Organization (WHO) guidelines for the treatment of isoniazid (H)-resistant (Hr) tuberculosis recommend a four-drug regimen: rifampicin (R), ethambutol (E), pyrazinamide (Z) and levofloxacin (Lfx), with or without H ([H]RZE-Lfx). This is used once Hr is known, such that patients complete 6 months of Lfx (≥6[H]RZE-6Lfx). This cohort study assessed the impact of fluoroquinolones (Fq) on treatment effectiveness, accounting for Hr mutations and degree of phenotypic resistance. This was a retrospective cohort study of 626 Hr tuberculosis patients notified in London, 2009-2013. Regimens were described and logistic regression undertaken of the association between regimen and negative regimen-specific outcomes (broadly, death due to tuberculosis, treatment failure or disease recurrence). Of 594 individuals with regimen information, 330 (55.6%) were treated with (H)RfZE (Rf=rifamycins) and 211 (35.5%) with (H)RfZE-Fq. The median overall treatment period was 11.9 months and median Z duration 2.1 months. In a univariable logistic regression model comparing (H)RfZE with and without Fqs, there was no difference in the odds of a negative regimen-specific outcome (baseline (H)RfZE, cluster-specific odds ratio 1.05 (95% CI 0.60-1.82), p=0.87; cluster NHS trust). Results varied minimally in a multivariable model. This odds ratio dropped (0.57, 95% CI 0.14-2.28) when Hr genotype was included, but this analysis lacked power (p=0.42). In a high-income setting, we found a 12-month (H)RfZE regimen with a short Z duration to be similarly effective for Hr tuberculosis with or without a Fq. This regimen may result in fewer adverse events than the WHO recommendations.
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- 2019
7. State of the art : a survey of current equipment and approaches in New Zealand university electronic music studios
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Harris, Ross, (and others)
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- 1991
8. Analysis of serological surveillance data : patterns of blood-borne infection and heterogeneity in people who inject drugs
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Harris, Ross Jeremy
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362.1969 - Abstract
A large proportion of blood-borne viruses (BBV) are transmitted via injecting drug use. Understanding patterns of risk and monitoring trends over time in people who inject drugs (PWID) is therefore a crucial part of developing public health policy. Risks of infection with hepatitis C and B (HCV, HBV) and HIV in PWID are investigated using serial cross-sectional surveillance data, in particular via force of infection (FOI) models. Standard models are extended to include a wealth of covariate data. Individual variability is considered via bivariate shared frailty models and correlations between infections. Gamma, inverse Gaussian and time-varying frailty models are fitted to investigate how variability in risk evolves throughout injecting career. Finally, models are extended to the trivariate case and different forms of component frailty models are proposed. Recent initiates were found to be at high risk of infection, in particular in London and the North West. Subsequently the FOI is broadly constant, and similar across different regions. Frailty models indicate that there is substantial individual variability in risk, although this declines over the course of injecting career. Females have higher overall risks of HCV and HBV, but are less heterogeneous than males. Including covariate data on demographics and a number of risk factors only resulted in modest reductions in frailty variance. Correlations between HCV-HBV and HBV-HIV associations were stronger than for HCV-HIV; trivariate models including additional pairwise components for HCV-HBV and HBV-HIV provided an improvement in model fit compared to a shared frailty model. Many of the results in this thesis point towards greater variation in risk at initiation, potentially due to the varied circumstances in which individuals start injecting, followed by more comparable risks in those with established injecting behaviour. The relative importance of injecting and sexual risk may explain patterns of risk and correlation in the three infections.
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- 2019
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9. Effectiveness of nationwide programmatic testing and treatment for latent tuberculosis infection in migrants in England: a retrospective, population-based cohort study
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Berrocal-Almanza, Luis C, Harris, Ross J, Collin, Simon M, Muzyamba, Morris C, Conroy, Olivia D, Mirza, Adil, O'Connell, Anne-Marie, Altass, Lynn, Anderson, Sarah R, Thomas, H Lucy, Campbell, Colin, Zenner, Dominik, Phin, Nick, Kon, Onn Min, Smith, E Grace, and Lalvani, Ajit
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- 2022
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10. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
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Koshy, Cherian, Ash, Amy, Wise, Emma, Moore, Nathan, Mori, Matilde, Cortes, Nick, Lynch, Jessica, Kidd, Stephen, Fairley, Derek, Curran, Tanya, McKenna, James, Adams, Helen, Fraser, Christophe, Golubchik, Tanya, Bonsall, David, Hassan-Ibrahim, Mohammed, Malone, Cassandra, Cogger, Benjamin, Wantoch, Michelle, Reynolds, Nicola, Warne, Ben, Maksimovic, Joshua, Spellman, Karla, McCluggage, Kathryn, John, Michaela, Beer, Robert, Afifi, Safiah, Morgan, Sian, Marchbank, Angela, Price, Anna, Kitchen, Christine, Gulliver, Huw, Merrick, Ian, Southgate, Joel, Guest, Martyn, Munn, Robert, Workman, Trudy, Connor, Thomas, Fuller, William, Bresner, Catherine, Snell, Luke, Patel, Amita, Charalampous, Themoula, Nebbia, Gaia, Batra, Rahul, Edgeworth, Jonathan, Robson, Samuel, Beckett, Angela, Aanensen, David, Underwood, Anthony, Yeats, Corin, Abudahab, Khalil, Taylor, Ben, Menegazzo, Mirko, Clark, Gemma, Smith, Wendy, Khakh, Manjinder, Fleming, Vicki, Lister, Michelle, Howson-Wells, Hannah, Berry, Louise, Boswell, Tim, Joseph, Amelia, Willingham, Iona, Jones, Carl, Holmes, Christopher, Bird, Paul, Helmer, Thomas, Fallon, Karlie, Tang, Julian, Raviprakash, Veena, Campbell, Sharon, Sheriff, Nicola, Blakey, Victoria, Williams, Lesley-Anne, Loose, Matthew, Holmes, Nadine, Moore, Christopher, Carlile, Matthew, Wright, Victoria, Sang, Fei, Debebe, Johnny, Coll, Francesc, Signell, Adrian, Betancor, Gilberto, Wilson, Harry, Eldirdiri, Sahar, Kenyon, Anita, Davis, Thomas, Pybus, Oliver, du Plessis, Louis, Zarebski, Alex, Raghwani, Jayna, Kraemer, Moritz, Francois, Sarah, Attwood, Stephen, Vasylyeva, Tetyana, Escalera Zamudio, Marina, Gutierrez, Bernardo, Torok, M. Estee, Hamilton, William, Goodfellow, Ian, Hall, Grant, Jahun, Aminu, Chaudhry, Yasmin, Hosmillo, Myra, Pinckert, Malte, Georgana, Iliana, Moses, Samuel, Lowe, Hannah, Bedford, Luke, Moore, Jonathan, Stonehouse, Susanne, Fisher, Chloe, Awan, Ali, BoYes, John, Breuer, Judith, Harris, Kathryn, Brown, Julianne, Shah, Divya, Atkinson, Laura, Lee, Jack, Storey, Nathaniel, Flaviani, Flavia, Alcolea-Medina, Adela, Williams, Rebecca, Vernet, Gabrielle, Chapman, Michael, Levett, Lisa, Heaney, Judith, Chatterton, Wendy, Pusok, Monika, Xu-McCrae, Li, Smith, Darren, Bashton, Matthew, Young, Gregory, Holmes, Alison, Randell, Paul, Cox, Alison, Madona, Pinglawathee, Bolt, Frances, Price, James, Mookerjee, Siddharth, Ragonnet-Cronin, Manon, F. Nascimento, Fabricia, Jorgensen, David, Siveroni, Igor, Johnson, Rob, Boyd, Olivia, Geidelberg, Lily, Volz, Erik, Rowan, Aileen, Taylor, Graham, Smollett, Katherine, Loman, Nicholas, Quick, Joshua, McMurray, Claire, Stockton, Joanne, Nicholls, Sam, Rowe, Will, Poplawski, Radoslaw, McNally, Alan, Martinez Nunez, Rocio, Mason, Jenifer, Robinson, Trevor, O'Toole, Elaine, Watts, Joanne, Breen, Cassie, Cowell, Angela, Sluga, Graciela, Machin, Nicholas, Ahmad, Shazaad, George, Ryan, Halstead, Fenella, Sivaprakasam, Venkat, Hogsden, Wendy, Illingworth, Chris, Jackson, Chris, Thomson, Emma, Shepherd, James, Asamaphan, Patawee, Niebel, Marc, Li, Kathy, Shah, Rajiv, Jesudason, Natasha, Tong, Lily, Broos, Alice, Mair, Daniel, Nichols, Jenna, Carmichael, Stephen, Nomikou, Kyriaki, Aranday-Cortes, Elihu, Johnson, Natasha, Starinskij, Igor, da Silva Filipe, Ana, Robertson, David, Orton, Richard, Hughes, Joseph, Vattipally, Sreenu, Singer, Joshua, Nickbakhsh, Seema, Hale, Antony, Macfarlane-Smith, Louissa, Harper, Katherine, Carden, Holli, Taha, Yusri, Payne, Brendan, Burton-Fanning, Shirelle, Waugh, Sheila, Collins, Jennifer, Eltringham, Gary, Rushton, Steven, O'Brien, Sarah, Bradley, Amanda, Maclean, Alasdair, Mollett, Guy, Blacow, Rachel, Templeton, Kate, McHugh, Martin, Dewar, Rebecca, Wastenge, Elizabeth, Dervisevic, Samir, Stanley, Rachael, Meader, Emma, Coupland, Lindsay, Smith, Louise, Graham, Clive, Barton, Edward, Padgett, Debra, Scott, Garren, Swindells, Emma, Greenaway, Jane, Nelson, Andrew, McCann, Clare, Yew, Wen, Andersson, Monique, Peto, Timothy, Justice, Anita, Eyre, David, Crook, Derrick, Sloan, Tim, Duckworth, Nichola, Walsh, Sarah, Chauhan, Anoop, Glaysher, Sharon, Bicknell, Kelly, Wyllie, Sarah, Elliott, Scott, Lloyd, Allyson, Impey, Robert, Levene, Nick, Monaghan, Lynn, Bradley, Declan, Wyatt, Tim, Allara, Elias, Pearson, Clare, Osman, Husam, Bosworth, Andrew, Robinson, Esther, Muir, Peter, Vipond, Ian, Hopes, Richard, Pymont, Hannah, Hutchings, Stephanie, Curran, Martin, Parmar, Surendra, Lackenby, Angie, Mbisa, Tamyo, Platt, Steven, Miah, Shahjahan, Bibby, David, Manso, Carmen, Hubb, Jonathan, Chand, Meera, Dabrera, Gavin, Ramsay, Mary, Bradshaw, Daniel, Thornton, Alicia, Myers, Richard, Schaefer, Ulf, Groves, Natalie, Gallagher, Eileen, Lee, David, Williams, David, Ellaby, Nicholas, Harrison, Ian, Hartman, Hassan, Manesis, Nikos, Patel, Vineet, Bishop, Chloe, Chalker, Vicki, Ledesma, Juan, Twohig, Katherine, Holden, Matthew, Shaaban, Sharif, Birchley, Alec, Adams, Alexander, Davies, Alisha, Gaskin, Amy, Plimmer, Amy, Gatica-Wilcox, Bree, McKerr, Caoimhe, Moore, Catherine, Williams, Chris, Heyburn, David, De Lacy, Elen, Hilvers, Ember, Downing, Fatima, Shankar, Giri, Jones, Hannah, Asad, Hibo, Coombes, Jason, Watkins, Joanne, Evans, Johnathan, Fina, Laia, Gifford, Laura, Gilbert, Lauren, Graham, Lee, Perry, Malorie, Morgan, Mari, Bull, Matthew, Cronin, Michelle, Pacchiarini, Nicole, Craine, Noel, Jones, Rachel, Howe, Robin, Corden, Sally, Rey, Sara, Kumziene-SummerhaYes, Sara, Taylor, Sarah, Cottrell, Simon, Jones, Sophie, Edwards, Sue, O'Grady, Justin, Page, Andrew, Mather, Alison, Baker, David, Rudder, Steven, Aydin, Alp, Kay, Gemma, Trotter, Alexander, Alikhan, Nabil-Fareed, de Oliveira Martins, Leonardo, Le-Viet, Thanh, Meadows, Lizzie, Casey, Anna, Ratcliffe, Liz, Simpson, David, Molnar, Zoltan, Thompson, Thomas, Acheson, Erwan, Masoli, Jane, Knight, Bridget, Ellard, Sian, Auckland, Cressida, Jones, Christopher, Mahungu, Tabitha, Irish-Tavares, Dianne, Haque, Tanzina, Hart, Jennifer, Witele, Eric, Fenton, Melisa, Dadrah, Ashok, Symmonds, Amanda, Saluja, Tranprit, Bourgeois, Yann, Scarlett, Garry, Loveson, Katie, Goudarzi, Salman, Fearn, Christopher, Cook, Kate, Dent, Hannah, Paul, Hannah, Partridge, David, Raza, Mohammad, Evans, Cariad, Johnson, Kate, Liggett, Steven, Baker, Paul, Bonner, Stephen, Essex, Sarah, Lyons, Ronan, Saeed, Kordo, Mahanama, Adhyana, Samaraweera, Buddhini, Silveira, Siona, Pelosi, Emanuela, Wilson-Davies, Eleri, Williams, Rachel, Kristiansen, Mark, Roy, Sunando, Williams, Charlotte, Cotic, Marius, Bayzid, Nadua, Westhorpe, Adam, Hartley, John, Jannoo, Riaz, Lowe, Helen, Karamani, Angeliki, Ensell, Leah, Prieto, Jacqui, Jeremiah, Sarah, Grammatopoulos, Dimitris, Pandey, Sarojini, Berry, Lisa, Jones, Katie, Richter, Alex, Beggs, Andrew, Best, Angus, Percival, Benita, Mirza, Jeremy, Megram, Oliver, Mayhew, Megan, Crawford, Liam, Ashcroft, Fiona, Moles-Garcia, Emma, Cumley, Nicola, Smith, Colin, Bucca, Giselda, Hesketh, Andrew, Blane, Beth, Girgis, Sophia, Leek, Danielle, Sridhar, Sushmita, Forrest, Sally, Cormie, Claire, Gill, Harmeet, Dias, Joana, Higginson, Ellen, Maes, Mailis, Young, Jamie, Kermack, Leanne, Gupta, Ravi, Ludden, Catherine, Peacock, Sharon, Palmer, Sophie, Churcher, Carol, Hadjirin, Nazreen, Carabelli, Alessandro, Brooks, Ellena, Smith, Kim, Galai, Katerina, McManus, Georgina, Ruis, Chris, Davidson, Rose, Rambaut, Andrew, Williams, Thomas, Balcazar, Carlos, Gallagher, Michael, O'Toole, Áine, Rooke, Stefan, Hill, Verity, Williamson, Kathleen, Stanton, Thomas, Michell, Stephen, Bewshea, Claire, Temperton, Ben, Michelsen, Michelle, Warwick-Dugdale, Joanna, Manley, Robin, Farbos, Audrey, Harrison, James, Sambles, Christine, Studholme, David, Jeffries, Aaron, Jackson, Leigh, Darby, Alistair, Hiscox, Julian, Paterson, Steve, Iturriza-Gomara, Miren, Jackson, Kathryn, Lucaci, Anita, Vamos, Edith, Hughes, Margaret, Rainbow, Lucille, Eccles, Richard, Nelson, Charlotte, Whitehead, Mark, Turtle, Lance, Haldenby, Sam, Gregory, Richard, Gemmell, Matthew, Wierzbicki, Claudia, Webster, Hermione, de Silva, Thushan, Smith, Nikki, Angyal, Adrienn, Lindsey, Benjamin, Groves, Danielle, Green, Luke, Wang, Dennis, Freeman, Timothy, Parker, Matthew, Keeley, Alexander, Parsons, Paul, Tucker, Rachel, Brown, Rebecca, Wyles, Matthew, Whiteley, Max, Zhang, Peijun, Gallis, Marta, Louka, Stavroula, Constantinidou, Chrystala, Unnikrishnan, Meera, Ott, Sascha, Cheng, Jeffrey, Bridgewater, Hannah, Frost, Lucy, Taylor-Joyce, Grace, Stark, Richard, Baxter, Laura, Alam, Mohammad, Brown, Paul, Aggarwal, Dinesh, Cerda, Alberto, Merrill, Tammy, Wilson, Rebekah, McClure, Patrick, Chappell, Joseph, Tsoleridis, Theocharis, Ball, Jonathan, Buck, David, Todd, John, Green, Angie, Trebes, Amy, MacIntyre-Cockett, George, de Cesare, Mariateresa, Alderton, Alex, Amato, Roberto, Ariani, Cristina, Beale, Mathew, Beaver, Charlotte, Bellis, Katherine, Betteridge, Emma, Bonfield, James, Danesh, John, Dorman, Matthew, Drury, Eleanor, Farr, Ben, Foulser, Luke, Goncalves, Sonia, Goodwin, Scott, Gourtovaia, Marina, Harrison, Ewan, Jackson, David, Jamrozy, Dorota, Johnston, Ian, Kane, Leanne, Kay, Sally, Keatley, Jon-Paul, Kwiatkowski, Dominic, Langford, Cordelia, Lawniczak, Mara, Letchford, Laura, Livett, Rich, Lo, Stephanie, Martincorena, Inigo, McGuigan, Samantha, Nelson, Rachel, Palmer, Steve, Park, Naomi, Patel, Minal, Prestwood, Liam, Puethe, Christoph, Quail, Michael, Rajatileka, Shavanthi, Scott, Carol, Shirley, Lesley, Sillitoe, John, Spencer Chapman, Michael, Thurston, Scott, Tonkin-Hill, Gerry, Weldon, Danni, Rajan, Diana, Bronner, Iraad, Aigrain, Louise, Redshaw, Nicholas, Lensing, Stefanie, Davies, Robert, Whitwham, Andrew, Liddle, Jennifier, Lewis, Kevin, Tovar-Corona, Jaime, Leonard, Steven, Durham, Jillian, Bassett, Andrew, McCarthy, Shane, Moll, Robin, James, Keith, Oliver, Karen, Makunin, Alex, Barrett, Jeff, Gunson, Rory, Twohig, Katherine A, Nyberg, Tommy, Zaidi, Asad, Thelwall, Simon, Sinnathamby, Mary A, Aliabadi, Shirin, Seaman, Shaun R, Harris, Ross J, Hope, Russell, Lopez-Bernal, Jamie, Charlett, Andre, De Angelis, Daniela, and Presanis, Anne M
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- 2022
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11. Seroprevalence of immunity to hepatitis A and hepatitis B among gay, bisexual and other men who have sex with men (GBMSM) attending sexual health clinics in London and Leeds, England, 2017–2018.
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Roche, Rachel, Simmons, Ruth, Allen, Hester, Glancy, Megan, Balan, Anca-Maria, Bolea, Maria, Harris, Ross, Desai, Monica, Mohammed, Hamish, Sabin, Caroline, Ijaz, Samreen, and Mandal, Sema
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- 2024
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12. Antibody persistence and neutralising activity in primary school students and staff: Prospective active surveillance, June to December 2020, England
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Ireland, Georgina, Jeffery-Smith, Anna, Zambon, Maria, Hoschler, Katja, Harris, Ross, Poh, John, Baawuah, Frances, Beckmann, Joanne, Okike, Ifeanyichukwu O, Ahmad, Shazaad, Garstang, Joanna, Brent, Andrew J, Brent, Bernadette, Aiano, Felicity, Amin-Chowdhury, Zahin, Letley, Louise, Jones, Samuel E I, Kall, Meaghan, Patel, Monika, Gopal, Robin, Borrow, Ray, Linley, Ezra, Amirthalingam, Gayatri, Brown, Kevin E, Ramsay, Mary E, and Ladhani, Shamez N
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- 2021
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13. Trends in undiagnosed HIV prevalence in England and implications for eliminating HIV transmission by 2030: an evidence synthesis model
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Presanis, Anne M, Harris, Ross J, Kirwan, Peter D, Miltz, Ada, Croxford, Sara, Heinsbroek, Ellen, Jackson, Christopher H, Mohammed, Hamish, Brown, Alison E, Delpech, Valerie C, Gill, O Noel, and Angelis, Daniela De
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- 2021
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14. Serological surveillance of SARS-CoV-2: Six-month trends and antibody response in a cohort of public health workers
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Harris, Ross J., Whitaker, Heather J., Andrews, Nick J., Aiano, Felicity, Amin-Chowdhury, Zahin, Flood, Jessica, Borrow, Ray, Linley, Ezra, Ahmad, Shazaad, Stapley, Lorraine, Hallis, Bassam, Amirthalingam, Gayatri, Höschler, Katja, Parker, Ben, Horsley, Alex, Brooks, Timothy J.G., Brown, Kevin E., Ramsay, Mary E., and Ladhani, Shamez N.
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- 2021
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15. Persistence of SARS-CoV-2 N-Antibody Response in Healthcare Workers, London, UK
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Shrotri, Madhumita, Harris, Ross J., Rodger, Alison, Planche, Timothy, Sanderson, Frances, Mahungu, Tabitha, McGregor, Alastair, Heath, Paul T., Brown, Colin S., Dunning, Jake, Hopkins, Susan, Ladhani, Shamez, and Chand, Meera
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Health - Abstract
The durability of antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease (COVID-19), is of scientific and strategic interest for public health systems [...]
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- 2021
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16. Cost-Effectiveness of One-Time Birth Cohort Screening for Hepatitis C as Part of the National Health Service Health Check Program in England
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Williams, Jack, Miners, Alec, Harris, Ross, Mandal, Sema, Simmons, Ruth, Ireland, Georgina, Hickman, Matthew, Gore, Charles, and Vickerman, Peter
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- 2019
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17. Effectiveness of pre-entry active tuberculosis and post-entry latent tuberculosis screening in new entrants to the UK: a retrospective, population-based cohort study
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Berrocal-Almanza, Luis C, Harris, Ross, Lalor, Maeve K, Muzyamba, Morris C, Were, John, O'Connell, Anne-Marie, Mirza, Adil, Kon, Onn-Min, Lalvani, Ajit, and Zenner, Dominik
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- 2019
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18. Transfer characteristics of a lithium chloride–potassium chloride molten salt
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Mullen, Eve, Harris, Ross, Graham, Dave, Rhodes, Chris, and Hodgson, Zara
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- 2017
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19. A modelling study of the impact of scaling up of HCV case finding and treatment for people who inject drugs in English region of Bristol and Severn
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Ward, Zoe, primary, Fraser, Hannah, additional, Trickey, Adam, additional, Kesten, Jo, additional, Gibson, Andy, additional, Reid, Leila, additional, Gordon, Fiona, additional, Miners, Alec, additional, Williams, Jack, additional, Hickman, Matthew, additional, Foster, Graham, additional, Desai, Monica, additional, Mandal, Sema, additional, Coughlan, Laura, additional, Simmons, Ruth, additional, Harris, Ross, additional, and Vickerman, Peter, additional
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- 2023
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20. Supplementary Table 1 from Circulating Folate, Vitamin B12, Homocysteine, Vitamin B12 Transport Proteins, and Risk of Prostate Cancer: a Case-Control Study, Systematic Review, and Meta-analysis
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Collin, Simon M., primary, Metcalfe, Chris, primary, Refsum, Helga, primary, Lewis, Sarah J., primary, Zuccolo, Luisa, primary, Smith, George Davey, primary, Chen, Lina, primary, Harris, Ross, primary, Davis, Michael, primary, Marsden, Gemma, primary, Johnston, Carole, primary, Lane, J. Athene, primary, Ebbing, Marta, primary, Bønaa, Kaare Harald, primary, Nygård, Ottar, primary, Ueland, Per Magne, primary, Grau, Maria V., primary, Baron, John A., primary, Donovan, Jenny L., primary, Neal, David E., primary, Hamdy, Freddie C., primary, Smith, A. David, primary, and Martin, Richard M., primary
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- 2023
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21. Data from Circulating Folate, Vitamin B12, Homocysteine, Vitamin B12 Transport Proteins, and Risk of Prostate Cancer: a Case-Control Study, Systematic Review, and Meta-analysis
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Collin, Simon M., primary, Metcalfe, Chris, primary, Refsum, Helga, primary, Lewis, Sarah J., primary, Zuccolo, Luisa, primary, Smith, George Davey, primary, Chen, Lina, primary, Harris, Ross, primary, Davis, Michael, primary, Marsden, Gemma, primary, Johnston, Carole, primary, Lane, J. Athene, primary, Ebbing, Marta, primary, Bønaa, Kaare Harald, primary, Nygård, Ottar, primary, Ueland, Per Magne, primary, Grau, Maria V., primary, Baron, John A., primary, Donovan, Jenny L., primary, Neal, David E., primary, Hamdy, Freddie C., primary, Smith, A. David, primary, and Martin, Richard M., primary
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- 2023
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22. Supplementary Table 2 from Circulating Folate, Vitamin B12, Homocysteine, Vitamin B12 Transport Proteins, and Risk of Prostate Cancer: a Case-Control Study, Systematic Review, and Meta-analysis
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Collin, Simon M., primary, Metcalfe, Chris, primary, Refsum, Helga, primary, Lewis, Sarah J., primary, Zuccolo, Luisa, primary, Smith, George Davey, primary, Chen, Lina, primary, Harris, Ross, primary, Davis, Michael, primary, Marsden, Gemma, primary, Johnston, Carole, primary, Lane, J. Athene, primary, Ebbing, Marta, primary, Bønaa, Kaare Harald, primary, Nygård, Ottar, primary, Ueland, Per Magne, primary, Grau, Maria V., primary, Baron, John A., primary, Donovan, Jenny L., primary, Neal, David E., primary, Hamdy, Freddie C., primary, Smith, A. David, primary, and Martin, Richard M., primary
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- 2023
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23. Probabilistic linkage of multiple data sources for estimating prevalence of problem drug users in England in 2018/19.
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Djennad, Abdelmajid, primary, Jahr, Stefan, additional, Harris, Ross, additional, and Charlett, Andre, additional
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- 2022
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24. Clonality, virulence and antimicrobial resistance of enteroaggregative Escherichia coli from Mirzapur, Bangladesh
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Chattaway, Marie Anne, Day, Michaela, Mtwale, Julia, White, Emma, Rogers, James, Day, Martin, Powell, David, Ahmad, Marwa, Harris, Ross, Talukder, Kaisar Ali, Wain, John, Jenkins, Claire, and Cravioto, Alejandro
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- 2017
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25. Household transmission of COVID-19 cases associated with SARS-CoV-2 delta variant (B.1.617.2): national case-control study
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Allen, Hester, Vusirikala, Amoolya, Flannagan, Joe, Twohig, Katherine A, Zaidi, Asad, Chudasama, Dimple, Lamagni, Theresa, Groves, Natalie, Turner, Charlie, Rawlinson, Christopher, Lopez-Bernal, Jamie, Harris, Ross, Charlett, Andre, Dabrera, Gavin, Kall, Meaghan, COVID-19 Genomics UK (COG-UK Consortium), and Apollo - University of Cambridge Repository
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England ,variant ,SARS-CoV-2 ,transmission ,COVID-19 ,Delta,household - Abstract
Background: The SARS-CoV-2 Delta variant (B.1.617.2), first detected in India, has rapidly become the dominant variant in England. Early reports suggest this variant has an increased growth rate suggesting increased transmissibility. This study indirectly assessed differences in transmissibility between the emergent Delta variant compared to the previously dominant Alpha variant (B.1.1.7). Methods: A matched case-control study was conducted to estimate the odds of household transmission (≥ 2 cases within 14 days) for Delta variant index cases compared with Alpha cases. Cases were derived from national surveillance data (March to June 2021). One-to-two matching was undertaken on geographical location of residence, time period of testing and property type, and a multivariable conditional logistic regression model was used for analysis. Findings: In total 5,976 genomically sequenced index cases in household clusters were matched to 11,952 sporadic index cases (single case within a household). 43.3% (n=2,586) of cases in household clusters were confirmed Delta variant compared to 40.4% (n= 4,824) of sporadic cases. The odds ratio of household transmission was 1.70 among Delta variant cases (95% CI 1.48-1.95, p
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- 2022
26. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
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Twohig, Katherine A, Nyberg, Tommy, Zaidi, Asad, Thelwall, Simon, Sinnathamby, Mary A, Aliabadi, Shirin, Seaman, Shaun R, Harris, Ross J, Hope, Russell, Lopez-Bernal, Jamie, Gallagher, Eileen, Charlett, Andre, De Angelis, Daniela, Presanis, Anne M, Dabrera, Gavin, COVID-19 Genomics UK (COG-UK) Consortium, Nyberg, Tommy [0000-0002-9436-0626], Seaman, Shaun [0000-0003-3726-5937], De Angelis, Daniela [0000-0001-6619-6112], Presanis, Anne [0000-0003-3078-4427], and Apollo - University of Cambridge Repository
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Adult ,Aged, 80 and over ,Male ,Emergency Medical Services ,Adolescent ,SARS-CoV-2 ,COVID-19 ,Middle Aged ,Severity of Illness Index ,Cohort Studies ,Hospitalization ,Young Adult ,England ,Child, Preschool ,Humans ,Female ,Child ,Aged ,Proportional Hazards Models - Abstract
BACKGROUND: The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March, 2021. It has since rapidly become the predominant lineage, owing to high transmissibility. It is suspected that the delta variant is associated with more severe disease than the previously dominant alpha (B.1.1.7) variant. We aimed to characterise the severity of the delta variant compared with the alpha variant by determining the relative risk of hospital attendance outcomes. METHODS: This cohort study was done among all patients with COVID-19 in England between March 29 and May 23, 2021, who were identified as being infected with either the alpha or delta SARS-CoV-2 variant through whole-genome sequencing. Individual-level data on these patients were linked to routine health-care datasets on vaccination, emergency care attendance, hospital admission, and mortality (data from Public Health England's Second Generation Surveillance System and COVID-19-associated deaths dataset; the National Immunisation Management System; and NHS Digital Secondary Uses Services and Emergency Care Data Set). The risk for hospital admission and emergency care attendance were compared between patients with sequencing-confirmed delta and alpha variants for the whole cohort and by vaccination status subgroups. Stratified Cox regression was used to adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination status. FINDINGS: Individual-level data on 43 338 COVID-19-positive patients (8682 with the delta variant, 34 656 with the alpha variant; median age 31 years [IQR 17-43]) were included in our analysis. 196 (2·3%) patients with the delta variant versus 764 (2·2%) patients with the alpha variant were admitted to hospital within 14 days after the specimen was taken (adjusted hazard ratio [HR] 2·26 [95% CI 1·32-3·89]). 498 (5·7%) patients with the delta variant versus 1448 (4·2%) patients with the alpha variant were admitted to hospital or attended emergency care within 14 days (adjusted HR 1·45 [1·08-1·95]). Most patients were unvaccinated (32 078 [74·0%] across both groups). The HRs for vaccinated patients with the delta variant versus the alpha variant (adjusted HR for hospital admission 1·94 [95% CI 0·47-8·05] and for hospital admission or emergency care attendance 1·58 [0·69-3·61]) were similar to the HRs for unvaccinated patients (2·32 [1·29-4·16] and 1·43 [1·04-1·97]; p=0·82 for both) but the precision for the vaccinated subgroup was low. INTERPRETATION: This large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant. Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant. FUNDING: Medical Research Council; UK Research and Innovation; Department of Health and Social Care; and National Institute for Health Research.
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- 2022
27. Enhanced surveillance of HIV-1 drug resistance in recently infected MSM in the UK
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Cunningham, Emma, Chan, Yuen-Ting, Aghaizu, Adamma, Bibby, David F., Murphy, Gary, Tosswill, Jennifer, Harris, Ross J., Myers, Richard, Field, Nigel, Delpech, Valerie, Cane, Patricia A., Gill, O. Noel, and Mbisa, Jean L.
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- 2017
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28. Epidemiology of HIV infection and associated behaviours among people who inject drugs in England, Wales, and Northern Ireland: Nearly 40 years on
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Croxford, Sara, primary, Emanuel, Eva, additional, Shah, Ammi, additional, Chau, Cuong, additional, Hope, Vivian, additional, Desai, Monica, additional, Ijaz, Samreen, additional, Shute, Justin, additional, Edmundson, Claire, additional, Harris, Ross J., additional, Delpech, Valerie, additional, and Phipps, Emily, additional
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- 2022
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29. Household transmission of COVID-19 cases associated with SARS-CoV-2 delta variant (B.1.617.2): national case-control study
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Allen, Hester, primary, Vusirikala, Amoolya, additional, Flannagan, Joe, additional, Twohig, Katherine A., additional, Zaidi, Asad, additional, Chudasama, Dimple, additional, Lamagni, Theresa, additional, Groves, Natalie, additional, Turner, Charlie, additional, Rawlinson, Christopher, additional, Lopez-Bernal, Jamie, additional, Harris, Ross, additional, Charlett, Andre, additional, Dabrera, Gavin, additional, and Kall, Meaghan, additional
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- 2022
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30. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
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Twohig, Katherine A, primary, Nyberg, Tommy, additional, Zaidi, Asad, additional, Thelwall, Simon, additional, Sinnathamby, Mary A, additional, Aliabadi, Shirin, additional, Seaman, Shaun R, additional, Harris, Ross J, additional, Hope, Russell, additional, Lopez-Bernal, Jamie, additional, Gallagher, Eileen, additional, Charlett, Andre, additional, De Angelis, Daniela, additional, Presanis, Anne M, additional, Dabrera, Gavin, additional, Koshy, Cherian, additional, Ash, Amy, additional, Wise, Emma, additional, Moore, Nathan, additional, Mori, Matilde, additional, Cortes, Nick, additional, Lynch, Jessica, additional, Kidd, Stephen, additional, Fairley, Derek, additional, Curran, Tanya, additional, McKenna, James, additional, Adams, Helen, additional, Fraser, Christophe, additional, Golubchik, Tanya, additional, Bonsall, David, additional, Hassan-Ibrahim, Mohammed, additional, Malone, Cassandra, additional, Cogger, Benjamin, additional, Wantoch, Michelle, additional, Reynolds, Nicola, additional, Warne, Ben, additional, Maksimovic, Joshua, additional, Spellman, Karla, additional, McCluggage, Kathryn, additional, John, Michaela, additional, Beer, Robert, additional, Afifi, Safiah, additional, Morgan, Sian, additional, Marchbank, Angela, additional, Price, Anna, additional, Kitchen, Christine, additional, Gulliver, Huw, additional, Merrick, Ian, additional, Southgate, Joel, additional, Guest, Martyn, additional, Munn, Robert, additional, Workman, Trudy, additional, Connor, Thomas, additional, Fuller, William, additional, Bresner, Catherine, additional, Snell, Luke, additional, Patel, Amita, additional, Charalampous, Themoula, additional, Nebbia, Gaia, additional, Batra, Rahul, additional, Edgeworth, Jonathan, additional, Robson, Samuel, additional, Beckett, Angela, additional, Aanensen, David, additional, Underwood, Anthony, additional, Yeats, Corin, additional, Abudahab, Khalil, additional, Taylor, Ben, additional, Menegazzo, Mirko, additional, Clark, Gemma, additional, Smith, Wendy, additional, Khakh, Manjinder, additional, Fleming, Vicki, additional, Lister, Michelle, additional, Howson-Wells, Hannah, additional, Berry, Louise, additional, Boswell, Tim, additional, Joseph, Amelia, additional, Willingham, Iona, additional, Jones, Carl, additional, Holmes, Christopher, additional, Bird, Paul, additional, Helmer, Thomas, additional, Fallon, Karlie, additional, Tang, Julian, additional, Raviprakash, Veena, additional, Campbell, Sharon, additional, Sheriff, Nicola, additional, Blakey, Victoria, additional, Williams, Lesley-Anne, additional, Loose, Matthew, additional, Holmes, Nadine, additional, Moore, Christopher, additional, Carlile, Matthew, additional, Wright, Victoria, additional, Sang, Fei, additional, Debebe, Johnny, additional, Coll, Francesc, additional, Signell, Adrian, additional, Betancor, Gilberto, additional, Wilson, Harry, additional, Eldirdiri, Sahar, additional, Kenyon, Anita, additional, Davis, Thomas, additional, Pybus, Oliver, additional, du Plessis, Louis, additional, Zarebski, Alex, additional, Raghwani, Jayna, additional, Kraemer, Moritz, additional, Francois, Sarah, additional, Attwood, Stephen, additional, Vasylyeva, Tetyana, additional, Escalera Zamudio, Marina, additional, Gutierrez, Bernardo, additional, Torok, M. Estee, additional, Hamilton, William, additional, Goodfellow, Ian, additional, Hall, Grant, additional, Jahun, Aminu, additional, Chaudhry, Yasmin, additional, Hosmillo, Myra, additional, Pinckert, Malte, additional, Georgana, Iliana, additional, Moses, Samuel, additional, Lowe, Hannah, additional, Bedford, Luke, additional, Moore, Jonathan, additional, Stonehouse, Susanne, additional, Fisher, Chloe, additional, Awan, Ali, additional, BoYes, John, additional, Breuer, Judith, additional, Harris, Kathryn, additional, Brown, Julianne, additional, Shah, Divya, additional, Atkinson, Laura, additional, Lee, Jack, additional, Storey, Nathaniel, additional, Flaviani, Flavia, additional, Alcolea-Medina, Adela, additional, Williams, Rebecca, additional, Vernet, Gabrielle, additional, Chapman, Michael, additional, Levett, Lisa, additional, Heaney, Judith, additional, Chatterton, Wendy, additional, Pusok, Monika, additional, Xu-McCrae, Li, additional, Smith, Darren, additional, Bashton, Matthew, additional, Young, Gregory, additional, Holmes, Alison, additional, Randell, Paul, additional, Cox, Alison, additional, Madona, Pinglawathee, additional, Bolt, Frances, additional, Price, James, additional, Mookerjee, Siddharth, additional, Ragonnet-Cronin, Manon, additional, F. Nascimento, Fabricia, additional, Jorgensen, David, additional, Siveroni, Igor, additional, Johnson, Rob, additional, Boyd, Olivia, additional, Geidelberg, Lily, additional, Volz, Erik, additional, Rowan, Aileen, additional, Taylor, Graham, additional, Smollett, Katherine, additional, Loman, Nicholas, additional, Quick, Joshua, additional, McMurray, Claire, additional, Stockton, Joanne, additional, Nicholls, Sam, additional, Rowe, Will, additional, Poplawski, Radoslaw, additional, McNally, Alan, additional, Martinez Nunez, Rocio, additional, Mason, Jenifer, additional, Robinson, Trevor, additional, O'Toole, Elaine, additional, Watts, Joanne, additional, Breen, Cassie, additional, Cowell, Angela, additional, Sluga, Graciela, additional, Machin, Nicholas, additional, Ahmad, Shazaad, additional, George, Ryan, additional, Halstead, Fenella, additional, Sivaprakasam, Venkat, additional, Hogsden, Wendy, additional, Illingworth, Chris, additional, Jackson, Chris, additional, Thomson, Emma, additional, Shepherd, James, additional, Asamaphan, Patawee, additional, Niebel, Marc, additional, Li, Kathy, additional, Shah, Rajiv, additional, Jesudason, Natasha, additional, Tong, Lily, additional, Broos, Alice, additional, Mair, Daniel, additional, Nichols, Jenna, additional, Carmichael, Stephen, additional, Nomikou, Kyriaki, additional, Aranday-Cortes, Elihu, additional, Johnson, Natasha, additional, Starinskij, Igor, additional, da Silva Filipe, Ana, additional, Robertson, David, additional, Orton, Richard, additional, Hughes, Joseph, additional, Vattipally, Sreenu, additional, Singer, Joshua, additional, Nickbakhsh, Seema, additional, Hale, Antony, additional, Macfarlane-Smith, Louissa, additional, Harper, Katherine, additional, Carden, Holli, additional, Taha, Yusri, additional, Payne, Brendan, additional, Burton-Fanning, Shirelle, additional, Waugh, Sheila, additional, Collins, Jennifer, additional, Eltringham, Gary, additional, Rushton, Steven, additional, O'Brien, Sarah, additional, Bradley, Amanda, additional, Maclean, Alasdair, additional, Mollett, Guy, additional, Blacow, Rachel, additional, Templeton, Kate, additional, McHugh, Martin, additional, Dewar, Rebecca, additional, Wastenge, Elizabeth, additional, Dervisevic, Samir, additional, Stanley, Rachael, additional, Meader, Emma, additional, Coupland, Lindsay, additional, Smith, Louise, additional, Graham, Clive, additional, Barton, Edward, additional, Padgett, Debra, additional, Scott, Garren, additional, Swindells, Emma, additional, Greenaway, Jane, additional, Nelson, Andrew, additional, McCann, Clare, additional, Yew, Wen, additional, Andersson, Monique, additional, Peto, Timothy, additional, Justice, Anita, additional, Eyre, David, additional, Crook, Derrick, additional, Sloan, Tim, additional, Duckworth, Nichola, additional, Walsh, Sarah, additional, Chauhan, Anoop, additional, Glaysher, Sharon, additional, Bicknell, Kelly, additional, Wyllie, Sarah, additional, Elliott, Scott, additional, Lloyd, Allyson, additional, Impey, Robert, additional, Levene, Nick, additional, Monaghan, Lynn, additional, Bradley, Declan, additional, Wyatt, Tim, additional, Allara, Elias, additional, Pearson, Clare, additional, Osman, Husam, additional, Bosworth, Andrew, additional, Robinson, Esther, additional, Muir, Peter, additional, Vipond, Ian, additional, Hopes, Richard, additional, Pymont, Hannah, additional, Hutchings, Stephanie, additional, Curran, Martin, additional, Parmar, Surendra, additional, Lackenby, Angie, additional, Mbisa, Tamyo, additional, Platt, Steven, additional, Miah, Shahjahan, additional, Bibby, David, additional, Manso, Carmen, additional, Hubb, Jonathan, additional, Chand, Meera, additional, Ramsay, Mary, additional, Bradshaw, Daniel, additional, Thornton, Alicia, additional, Myers, Richard, additional, Schaefer, Ulf, additional, Groves, Natalie, additional, Lee, David, additional, Williams, David, additional, Ellaby, Nicholas, additional, Harrison, Ian, additional, Hartman, Hassan, additional, Manesis, Nikos, additional, Patel, Vineet, additional, Bishop, Chloe, additional, Chalker, Vicki, additional, Ledesma, Juan, additional, Twohig, Katherine, additional, Holden, Matthew, additional, Shaaban, Sharif, additional, Birchley, Alec, additional, Adams, Alexander, additional, Davies, Alisha, additional, Gaskin, Amy, additional, Plimmer, Amy, additional, Gatica-Wilcox, Bree, additional, McKerr, Caoimhe, additional, Moore, Catherine, additional, Williams, Chris, additional, Heyburn, David, additional, De Lacy, Elen, additional, Hilvers, Ember, additional, Downing, Fatima, additional, Shankar, Giri, additional, Jones, Hannah, additional, Asad, Hibo, additional, Coombes, Jason, additional, Watkins, Joanne, additional, Evans, Johnathan, additional, Fina, Laia, additional, Gifford, Laura, additional, Gilbert, Lauren, additional, Graham, Lee, additional, Perry, Malorie, additional, Morgan, Mari, additional, Bull, Matthew, additional, Cronin, Michelle, additional, Pacchiarini, Nicole, additional, Craine, Noel, additional, Jones, Rachel, additional, Howe, Robin, additional, Corden, Sally, additional, Rey, Sara, additional, Kumziene-SummerhaYes, Sara, additional, Taylor, Sarah, additional, Cottrell, Simon, additional, Jones, Sophie, additional, Edwards, Sue, additional, O'Grady, Justin, additional, Page, Andrew, additional, Mather, Alison, additional, Baker, David, additional, Rudder, Steven, additional, Aydin, Alp, additional, Kay, Gemma, additional, Trotter, Alexander, additional, Alikhan, Nabil-Fareed, additional, de Oliveira Martins, Leonardo, additional, Le-Viet, Thanh, additional, Meadows, Lizzie, additional, Casey, Anna, additional, Ratcliffe, Liz, additional, Simpson, David, additional, Molnar, Zoltan, additional, Thompson, Thomas, additional, Acheson, Erwan, additional, Masoli, Jane, additional, Knight, Bridget, additional, Ellard, Sian, additional, Auckland, Cressida, additional, Jones, Christopher, additional, Mahungu, Tabitha, additional, Irish-Tavares, Dianne, additional, Haque, Tanzina, additional, Hart, Jennifer, additional, Witele, Eric, additional, Fenton, Melisa, additional, Dadrah, Ashok, additional, Symmonds, Amanda, additional, Saluja, Tranprit, additional, Bourgeois, Yann, additional, Scarlett, Garry, additional, Loveson, Katie, additional, Goudarzi, Salman, additional, Fearn, Christopher, additional, Cook, Kate, additional, Dent, Hannah, additional, Paul, Hannah, additional, Partridge, David, additional, Raza, Mohammad, additional, Evans, Cariad, additional, Johnson, Kate, additional, Liggett, Steven, additional, Baker, Paul, additional, Bonner, Stephen, additional, Essex, Sarah, additional, Lyons, Ronan, additional, Saeed, Kordo, additional, Mahanama, Adhyana, additional, Samaraweera, Buddhini, additional, Silveira, Siona, additional, Pelosi, Emanuela, additional, Wilson-Davies, Eleri, additional, Williams, Rachel, additional, Kristiansen, Mark, additional, Roy, Sunando, additional, Williams, Charlotte, additional, Cotic, Marius, additional, Bayzid, Nadua, additional, Westhorpe, Adam, additional, Hartley, John, additional, Jannoo, Riaz, additional, Lowe, Helen, additional, Karamani, Angeliki, additional, Ensell, Leah, additional, Prieto, Jacqui, additional, Jeremiah, Sarah, additional, Grammatopoulos, Dimitris, additional, Pandey, Sarojini, additional, Berry, Lisa, additional, Jones, Katie, additional, Richter, Alex, additional, Beggs, Andrew, additional, Best, Angus, additional, Percival, Benita, additional, Mirza, Jeremy, additional, Megram, Oliver, additional, Mayhew, Megan, additional, Crawford, Liam, additional, Ashcroft, Fiona, additional, Moles-Garcia, Emma, additional, Cumley, Nicola, additional, Smith, Colin, additional, Bucca, Giselda, additional, Hesketh, Andrew, additional, Blane, Beth, additional, Girgis, Sophia, additional, Leek, Danielle, additional, Sridhar, Sushmita, additional, Forrest, Sally, additional, Cormie, Claire, additional, Gill, Harmeet, additional, Dias, Joana, additional, Higginson, Ellen, additional, Maes, Mailis, additional, Young, Jamie, additional, Kermack, Leanne, additional, Gupta, Ravi, additional, Ludden, Catherine, additional, Peacock, Sharon, additional, Palmer, Sophie, additional, Churcher, Carol, additional, Hadjirin, Nazreen, additional, Carabelli, Alessandro, additional, Brooks, Ellena, additional, Smith, Kim, additional, Galai, Katerina, additional, McManus, Georgina, additional, Ruis, Chris, additional, Davidson, Rose, additional, Rambaut, Andrew, additional, Williams, Thomas, additional, Balcazar, Carlos, additional, Gallagher, Michael, additional, O'Toole, Áine, additional, Rooke, Stefan, additional, Hill, Verity, additional, Williamson, Kathleen, additional, Stanton, Thomas, additional, Michell, Stephen, additional, Bewshea, Claire, additional, Temperton, Ben, additional, Michelsen, Michelle, additional, Warwick-Dugdale, Joanna, additional, Manley, Robin, additional, Farbos, Audrey, additional, Harrison, James, additional, Sambles, Christine, additional, Studholme, David, additional, Jeffries, Aaron, additional, Jackson, Leigh, additional, Darby, Alistair, additional, Hiscox, Julian, additional, Paterson, Steve, additional, Iturriza-Gomara, Miren, additional, Jackson, Kathryn, additional, Lucaci, Anita, additional, Vamos, Edith, additional, Hughes, Margaret, additional, Rainbow, Lucille, additional, Eccles, Richard, additional, Nelson, Charlotte, additional, Whitehead, Mark, additional, Turtle, Lance, additional, Haldenby, Sam, additional, Gregory, Richard, additional, Gemmell, Matthew, additional, Wierzbicki, Claudia, additional, Webster, Hermione, additional, de Silva, Thushan, additional, Smith, Nikki, additional, Angyal, Adrienn, additional, Lindsey, Benjamin, additional, Groves, Danielle, additional, Green, Luke, additional, Wang, Dennis, additional, Freeman, Timothy, additional, Parker, Matthew, additional, Keeley, Alexander, additional, Parsons, Paul, additional, Tucker, Rachel, additional, Brown, Rebecca, additional, Wyles, Matthew, additional, Whiteley, Max, additional, Zhang, Peijun, additional, Gallis, Marta, additional, Louka, Stavroula, additional, Constantinidou, Chrystala, additional, Unnikrishnan, Meera, additional, Ott, Sascha, additional, Cheng, Jeffrey, additional, Bridgewater, Hannah, additional, Frost, Lucy, additional, Taylor-Joyce, Grace, additional, Stark, Richard, additional, Baxter, Laura, additional, Alam, Mohammad, additional, Brown, Paul, additional, Aggarwal, Dinesh, additional, Cerda, Alberto, additional, Merrill, Tammy, additional, Wilson, Rebekah, additional, McClure, Patrick, additional, Chappell, Joseph, additional, Tsoleridis, Theocharis, additional, Ball, Jonathan, additional, Buck, David, additional, Todd, John, additional, Green, Angie, additional, Trebes, Amy, additional, MacIntyre-Cockett, George, additional, de Cesare, Mariateresa, additional, Alderton, Alex, additional, Amato, Roberto, additional, Ariani, Cristina, additional, Beale, Mathew, additional, Beaver, Charlotte, additional, Bellis, Katherine, additional, Betteridge, Emma, additional, Bonfield, James, additional, Danesh, John, additional, Dorman, Matthew, additional, Drury, Eleanor, additional, Farr, Ben, additional, Foulser, Luke, additional, Goncalves, Sonia, additional, Goodwin, Scott, additional, Gourtovaia, Marina, additional, Harrison, Ewan, additional, Jackson, David, additional, Jamrozy, Dorota, additional, Johnston, Ian, additional, Kane, Leanne, additional, Kay, Sally, additional, Keatley, Jon-Paul, additional, Kwiatkowski, Dominic, additional, Langford, Cordelia, additional, Lawniczak, Mara, additional, Letchford, Laura, additional, Livett, Rich, additional, Lo, Stephanie, additional, Martincorena, Inigo, additional, McGuigan, Samantha, additional, Nelson, Rachel, additional, Palmer, Steve, additional, Park, Naomi, additional, Patel, Minal, additional, Prestwood, Liam, additional, Puethe, Christoph, additional, Quail, Michael, additional, Rajatileka, Shavanthi, additional, Scott, Carol, additional, Shirley, Lesley, additional, Sillitoe, John, additional, Spencer Chapman, Michael, additional, Thurston, Scott, additional, Tonkin-Hill, Gerry, additional, Weldon, Danni, additional, Rajan, Diana, additional, Bronner, Iraad, additional, Aigrain, Louise, additional, Redshaw, Nicholas, additional, Lensing, Stefanie, additional, Davies, Robert, additional, Whitwham, Andrew, additional, Liddle, Jennifier, additional, Lewis, Kevin, additional, Tovar-Corona, Jaime, additional, Leonard, Steven, additional, Durham, Jillian, additional, Bassett, Andrew, additional, McCarthy, Shane, additional, Moll, Robin, additional, James, Keith, additional, Oliver, Karen, additional, Makunin, Alex, additional, Barrett, Jeff, additional, and Gunson, Rory, additional
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- 2022
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31. Bayesian modeling to unmask and predict influenza A/H1N1pdm dynamics in London
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Birrell, Paul J., Ketsetzis, Georgios, Gay, Nigel J., Cooper, Ben S., Presanis, Anne M., Harris, Ross J., Charlett, André, Zhang, Xu-Sheng, White, Peter J., Pebody, Richard G., and De Angelis, Daniela
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- 2011
32. Associations of circulating and dietary vitamin D with prostate cancer risk: a systematic review and dose-response meta-analysis
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Gilbert, Rebecca, Martin, Richard M., Beynon, Rebecca, Harris, Ross, Savovic, Jelena, Zuccolo, Luisa, Bekkering, Geertruida E., Fraser, William D., Sterne, Jonathan A. C., and Metcalfe, Chris
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- 2011
33. Associations of Circulating C-Reactive Protein and Interleukin-6 with Cancer Risk: Findings from Two Prospective Cohorts and a Meta-Analysis
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Heikkilä, Katriina, Harris, Ross, Lowe, Gordon, Rumley, Ann, Yarnell, John, Gallacher, John, Ben-Shlomo, Yoav, Ebrahim, Shah, and Lawlor, Debbie A.
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- 2009
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34. Recovery of Impairments after Severe Traumatic Brain Injury: Findings from a Prospective, Multicentre Study
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Tate, Robyn L, Harris, Ross D, Cameron, Ian D, Myles, Bridget M, Winstanley, Julie B, Hodgkinson, Adeline E, Baguley, Ian J, and Harradine, Peter G
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- 2006
35. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: a cohort study
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Twohig, Katherine A, Nyberg, Tommy, Zaidi, Asad, Thelwall, Simon, Sinnathamby, Mary A, Aliabadi, Shirin, Seaman, Shaun R, Harris, Ross J, Hope, Russell, Lopez-Bernal, Jamie, Gallagher, Eileen, Charlett, Andre, De Angelis, Daniela, Presanis, Anne M, Dabrera, Gavin, and COVID-19 Genomics UK (COG-UK) consortium
- Abstract
BACKGROUND: The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March, 2021. It has since rapidly become the predominant lineage, owing to high transmissibility. It is suspected that the delta variant is associated with more severe disease than the previously dominant alpha (B.1.1.7) variant. We aimed to characterise the severity of the delta variant compared with the alpha variant by determining the relative risk of hospital attendance outcomes. METHODS: This cohort study was done among all patients with COVID-19 in England between March 29 and May 23, 2021, who were identified as being infected with either the alpha or delta SARS-CoV-2 variant through whole-genome sequencing. Individual-level data on these patients were linked to routine health-care datasets on vaccination, emergency care attendance, hospital admission, and mortality (data from Public Health England's Second Generation Surveillance System and COVID-19-associated deaths dataset; the National Immunisation Management System; and NHS Digital Secondary Uses Services and Emergency Care Data Set). The risk for hospital admission and emergency care attendance were compared between patients with sequencing-confirmed delta and alpha variants for the whole cohort and by vaccination status subgroups. Stratified Cox regression was used to adjust for age, sex, ethnicity, deprivation, recent international travel, area of residence, calendar week, and vaccination status. FINDINGS: Individual-level data on 43 338 COVID-19-positive patients (8682 with the delta variant, 34 656 with the alpha variant; median age 31 years [IQR 17-43]) were included in our analysis. 196 (2·3%) patients with the delta variant versus 764 (2·2%) patients with the alpha variant were admitted to hospital within 14 days after the specimen was taken (adjusted hazard ratio [HR] 2·26 [95% CI 1·32-3·89]). 498 (5·7%) patients with the delta variant versus 1448 (4·2%) patients with the alpha variant were admitted to hospital or attended emergency care within 14 days (adjusted HR 1·45 [1·08-1·95]). Most patients were unvaccinated (32 078 [74·0%] across both groups). The HRs for vaccinated patients with the delta variant versus the alpha variant (adjusted HR for hospital admission 1·94 [95% CI 0·47-8·05] and for hospital admission or emergency care attendance 1·58 [0·69-3·61]) were similar to the HRs for unvaccinated patients (2·32 [1·29-4·16] and 1·43 [1·04-1·97]; p=0·82 for both) but the precision for the vaccinated subgroup was low. INTERPRETATION: This large national study found a higher hospital admission or emergency care attendance risk for patients with COVID-19 infected with the delta variant compared with the alpha variant. Results suggest that outbreaks of the delta variant in unvaccinated populations might lead to a greater burden on health-care services than the alpha variant. FUNDING: Medical Research Council; UK Research and Innovation; Department of Health and Social Care; and National Institute for Health Research.
- Published
- 2021
36. Changes in characteristics and case-severity in patients hospitalised with influenza A (H1N1) pdm09 infection between two epidemic waves-England, 2009-2010
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Plumb, Ian D, Harris, Ross, Green, Helen K, Ellis, Joanna, Baisley, Kathy, and Pebody, Richard G
- Abstract
BACKGROUND: During 2009-2010, pandemic influenza A (H1N1) pdm09 virus (pH1N1) infections in England occurred in two epidemic waves. Reasons for a reported increase in case-severity during the second wave are unclear. METHODS: We analysed hospital-based surveillance for patients with pH1N1 infections in England during 2009-2010 and linked national data sets to estimate ethnicity, socio-economic status and death within 28 days of admission. We used multivariable logistic regression to assess whether changes in demographic, clinical and management characteristics of patients could explain an increase in ICU admission or death, and accounted for missing values using multiple imputation. RESULTS: During the first wave, 54/960 (6%) hospitalised patients required intensive care and 21/960 (2%) died; during the second wave 143/1420 (10%) required intensive care and 55/1420 (4%) died. In a multivariable model, during the second wave patients were less likely to be from an ethnic minority (OR 0.33, 95% CI 0.26-0.42), have an elevated deprivation score (OR 0.75, 95% CI 0.68-0.83), have known comorbidity (OR 0.78, 95% CI 0.63-0.97) or receive antiviral therapy ≤2 days before onset (OR 0.72, 95% CI 0.56-0.92). Increased case-severity during the second wave was not explained by changes in demographic, clinical or management characteristics. CONCLUSIONS: Monitoring changes in patient characteristics could help target interventions during multiple waves of COVID-19 or a future influenza pandemic. To understand and respond to changes in case-severity, surveillance is needed that includes additional factors such as admission thresholds and seasonal coinfections.
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- 2021
37. Effect of Vaccination on Household Transmission of SARS-CoV-2 in England
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Harris, Ross J., primary, Hall, Jennifer A., additional, Zaidi, Asad, additional, Andrews, Nick J., additional, Dunbar, J. Kevin, additional, and Dabrera, Gavin, additional
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- 2021
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38. The impact of direct‐acting antivirals on hepatitis C viraemia among people who inject drugs in England; real‐world data 2011–2018
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Bardsley, Megan, primary, Heinsbroek, Ellen, additional, Harris, Ross, additional, Croxford, Sara, additional, Edmundson, Claire, additional, Hope, Vivian, additional, Hassan, Nasra, additional, Ijaz, Samreen, additional, Mandal, Sema, additional, Shute, Justin, additional, Hutchinson, Sharon J., additional, Hickman, Matthew, additional, Sinka, Katy, additional, and Phipps, Emily, additional
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- 2021
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39. Antibody persistence and neutralising activity in primary school students and staff: prospective active surveillance, June to December 2020, England
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Ireland, Georgina, primary, Jeffery-Smith, Anna, additional, Zambon, Maria, additional, Hoschler, Katja, additional, Harris, Ross, additional, Poh, John, additional, Baawuah, Frances, additional, Beckmann, Joanne, additional, Okike, Ifeanyichukwu O, additional, Ahmad, Shazaad, additional, Garstang, Joanna, additional, Brent, Andrew J, additional, Brent, Bernadette, additional, Aiano, Felicity, additional, Amin-Chowdhury, Zahin, additional, Letley, Louise, additional, Jones, Samuel E I, additional, Kall, Meaghan, additional, Patel, Monika, additional, Gopal, Robin, additional, Borrow, Ray, additional, Linley, Ezra, additional, Amirthalingam, Gayatri, additional, Brown, Kevin E, additional, Ramsay, Mary E, additional, and Ladhani, Shamez N, additional
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- 2021
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40. Prospective evaluation of the cost of diagnosis and treatment of invasive fungal disease in a cohort of adult haematology patients in the UK
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Ceesay, M. Mansour, Sadique, Zia, Harris, Ross, Ehrlich, Alice, Adams, Elisabeth J., and Pagliuca, Antonio
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- 2015
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41. Treatment of Latent Tuberculosis Infection
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Zenner, Dominik, Stagg, Helen R., Harris, Ross J., and Abubakar, Ibrahim
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- 2015
42. Risk of hospital admission for patients with SARS-CoV-2 variant B.1.1.7: cohort analysis
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Nyberg, Tommy, primary, Twohig, Katherine A, additional, Harris, Ross J, additional, Seaman, Shaun R, additional, Flannagan, Joe, additional, Allen, Hester, additional, Charlett, Andre, additional, De Angelis, Daniela, additional, Dabrera, Gavin, additional, and Presanis, Anne M, additional
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- 2021
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43. On the Sensitivity and Specificity of Postmortem Upper Respiratory Tract Testing for SARS-CoV-2
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Hall, Jennifer A, primary, Harris, Ross J, additional, Emmett, Hannah E, additional, Lowe, Belinda, additional, Singanayagam, Anika, additional, Twohig, Katherine A, additional, Zaidi, Asad, additional, Kall, Meaghan, additional, Zambon, Maria, additional, and Dabrera, Gavin, additional
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- 2021
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44. THE AUSTRALIAN HEALTH SYSTEM: CONTINUITY AND CHANGE
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HARRIS, MARY G. and HARRIS, ROSS D.
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- 1998
45. Use of antiviral drugs to reduce household transmission of pandemic (H1N1) 2009, United Kingdom
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Pebody, Richard G., Harris, Ross, Kafatos, George, Chamberland, Mary, Campbell, Colin, Nguyen-Van-Tam, Jonathan S., McLean, Estelle, Andrews, Nick, White, Peter J., Wynne-Evans, Edward, Green, Jon, Ellis, Joanna, Wreghitt, Tim, Bracebridge, Sam, Ihekweazu, Chikwe, Oliver, Isabel, Smith, Gillian, Hawkins, Colin, Salmon, Roland, Smyth, Brian, McMenamin, Jim, Zambon, Maria, Phin, Nick, and Watson, John M.
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Medical research -- Health aspects -- Analysis -- Usage ,Medicine, Experimental -- Health aspects -- Analysis -- Usage ,Swine influenza -- Risk factors -- Health aspects -- Analysis ,Avian influenza viruses -- Health aspects -- Analysis -- Usage ,Antiviral agents -- Usage -- Health aspects -- Analysis ,Public health -- Health aspects -- Analysis -- Usage ,Disease transmission -- Risk factors -- Health aspects -- Analysis ,Algorithms -- Health aspects -- Analysis -- Usage ,Algorithm ,Health - Abstract
Following emergence of pandemic influenza A (H1N1) 2009 in North America in spring 2009 (1,2), global spread of the virus was rapid (3,4). In the United Kingdom, the first confirmed [...]
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- 2011
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46. Improving health service management education: the manager speaks
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Harris, Mary G., Harris, Ross D., and Tapsell, Linda
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- 1993
47. Treatment of Latent Tuberculosis Infection: A Network Meta-analysis
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Stagg, Helen R., Zenner, Dominik, Harris, Ross J., Muñoz, Laura, Lipman, Marc C., and Abubakar, Ibrahim
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- 2014
48. Recapture or Precapture? Fallibility of Standard Capture-Recapture Methods in the Presence of Referrals Between Sources
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Jones, Hayley E., Hickman, Matthew, Welton, Nicky J., De Angelis, Daniela, Harris, Ross J., and Ades, A. E.
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- 2014
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49. Characterising post-COVID syndrome more than 6 months after acute infection in adults; prospective longitudinal cohort study, England
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Amin-Chowdhury, Zahin, primary, Harris, Ross J, additional, Aiano, Felicity, additional, Zavala, Maria, additional, Bertran, Marta, additional, Borrow, Ray, additional, Linley, Ezra, additional, Ahmad, Shazaad, additional, Parker, Ben, additional, Horsley, Alex, additional, Hallis, Bassam, additional, Flood, Jessica, additional, Brown, Kevin E, additional, Amirthalingam, Gayatri, additional, Ramsay, Mary E, additional, Andrews, Nick, additional, and Ladhani, Shamez N, additional
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- 2021
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50. Completeness of tuberculosis (TB) notification: inventory studies and capture-recapture analyses, six European Union countries, 2014 to 2016
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Straetemans, Masja, Bakker, Mirjam I, Alba, Sandra, Mergenthaler, Christina, Rood, Ente, Andersen, Peter H, Schimmel, Henrieke, Simunovic, Aleksandar, Svetina, Petra, Carvalho, Carlos, Lyytikäinen, Outi, Abubakar, Ibrahim, Harris, Ross J, Ködmön, Csaba, van der Werf, Marieke J, and van Hest, Rob
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Portugal ,tuberculosis ,Croatia ,statistics ,Denmark ,Slovenia ,surveillance ,epidemiology ,Finland ,Netherlands - Published
- 2020
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