45 results on '"Harrison, Justin R."'
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2. Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis
3. Chemical Validation of Trypanothione Synthetase
4. 2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization
5. PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis
6. Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease
7. Synthesis of medium-ring lactones via tandem methylenation/Claisen rearrangement of cyclic carbonates
8. Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis
9. A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
10. Validation of the VA-One Periodic Subsystem Module with the Goal to Increase Accuracy of SEA Subsystems in the High Frequency Regime
11. A concise synthesis of the octalactins
12. N-Myristoyltransferase Is a Cell Wall Target in Aspergillus fumigatus
13. Lead Optimization of a Pyrazole Sulfonamide Series of Trypanosoma brucei N-Myristoyltransferase Inhibitors: Identification and Evaluation of CNS Penetrant Compounds as Potential Treatments for Stage 2 Human African Trypanosomiasis
14. Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors
15. Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors
16. ChemInform Abstract: Enantioselective Synthesis of Alkyl-Substituted Eight-Membered Lactones by Claisen Rearrangement.
17. ChemInform Abstract: Studies Towards the Preparation of Sparteine-Like Diamines for Asymmetric Synthesis.
18. ChemInform Abstract: Synthesis of Medium-Ring Lactones via Tandem Methylenation/Claisen Rearrangement of Cyclic Carbonates.
19. ChemInform Abstract: Asymmetric Synthesis of N-Substituted (R)-2-[(Pyrrolidin-1-yl)methyl]pyrrolidines
20. ChemInform Abstract: Evaluation of a Sparteine-Like Diamine for Asymmetric Synthesis.
21. A Concise Synthesis of the Octalactins
22. The Horner—Wadsworth—Emmons Reaction in the Synthesis of Macrocyclic Peptides: The Trp-His-Gly-Arg Derived Macrocycle of Moroidin.
23. Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation–substitution of N-(tert-butoxycarbonyl)pyrrolidine
24. ChemInform Abstract: Synthesis of Medium‐Ring Lactones via Tandem Methylenation/Claisen Rearrangement of Cyclic Carbonates.
25. ChemInform Abstract: Indium Metal as a Reducing Agent in Organic Synthesis.
26. ChemInform Abstract: Indium as a Reducing Agent: Reduction of Oximes.
27. ASYMMETRIC SYNTHESIS OF N-SUBSTITUTED (R)-2-[(PYRROLIDIN-1-YL)METHYL]PYRROLIDINES
28. Indium metal as a reducing agent in organic synthesis
29. Evaluation of a sparteine-like diamine for asymmetric synthesis
30. Diastereoselective synthesis of sparteine analogues via lithiation–electrophilic quench of N-Boc bispidines
31. Bispidine-derived N-acyliminium ions in synthesis: stereocontrolled construction of the BCD rings of sparteine
32. Synthesis of medium-ring lactones via tandem methylenation/Claisen rearrangement of cyclic carbonates
33. Lead Optimization of a PyrazoleSulfonamide Seriesof Trypanosoma bruceiN-Myristoyltransferase Inhibitors: Identification and Evaluationof CNS Penetrant Compounds as Potential Treatments for Stage 2 HumanAfrican Trypanosomiasis.
34. Enantioselective Synthesis of Alkyl-substituted Eight-membered Lactones by Claisen Rearrangement
35. Studies towards the preparation of sparteine-like diamines for asymmetric synthesis †
36. Design, Synthesis and Biological Evaluation of Trypanosoma brucei Trypanothione Synthetase Inhibitors.
37. The Horner–Wadsworth–Emmons reaction in the synthesis of macrocyclic peptides: the Trp-His-Gly-Arg derived macrocycle of moroidin
38. Indium as a Reducing Agent: Reduction of Oximes.
39. ChemInform Abstract: Asymmetric Synthesis of N-Substituted (R)-2-[(Pyrrolidin-1-yl)methyl]pyrrolidines.
40. ChemInform Abstract: Evaluation of a Sparteine-Like Diamine for Asymmetric Synthesis.
41. ChemInform Abstract: Synthesis of Medium-Ring Lactones via Tandem Methylenation/Claisen Rearrangement of Cyclic Carbonates.
42. ChemInform Abstract: Studies Towards the Preparation of Sparteine-Like Diamines for Asymmetric Synthesis.
43. ChemInform Abstract: Enantioselective Synthesis of Alkyl-Substituted Eight-Membered Lactones by Claisen Rearrangement.
44. Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.
45. Synthesis of sparteine-like chiral diamines and evaluation in the enantioselective lithiation-substitution of N-(tert-butoxycarbonyl)pyrrolidine.
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