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3. Comparison of Clinical Features Between Primary and Secondary Breast Diffuse Large B Cell Lymphoma: A Yokohama Cooperative Study Group for Hematology Multicenter Retrospective Study

Author

Takahashi, Hiroyuki, Sakai, Rika, Sakuma, Takayuki, Matsumura, Ayako, Miyashita, Kazuho, Ishii, Yoshimi, Nakajima, Yuki, Numata, Ayumi, Hattori, Yukako, Miyazaki, Takuya, Hashimoto, Chizuko, Koharazawa, Hideyuki, Takemura, Sachiya, Taguchi, Jun, Fujimaki, Katsumichi, Fujita, Hiroyuki, and Nakajima, Hideaki

Published
2021
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4. Author Response: Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

Author

Mure, Ayumi, primary, Sugiura, Yuki, additional, Maeda, Rae, additional, Honda, Kohei, additional, Sakurai, Nozomu, additional, Takahashi, Yuuki, additional, Watada, Masayoshi, additional, Katoh, Toshihiko, additional, Gotoh, Aina, additional, Gotoh, Yasuhiro, additional, Taniguchi, Itsuki, additional, Nakamura, Keiji, additional, Hayashi, Tetsuya, additional, Katayama, Takane, additional, Uemura, Tadashi, additional, and Hattori, Yukako, additional

Published
2023
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5. Identification of key yeast species and microbe–microbe interactions impacting larval growth of Drosophila in the wild

Author

Mure, Ayumi, primary, Sugiura, Yuki, additional, Maeda, Rae, additional, Honda, Kohei, additional, Sakurai, Nozomu, additional, Takahashi, Yuuki, additional, Watada, Masayoshi, additional, Katoh, Toshihiko, additional, Gotoh, Aina, additional, Gotoh, Yasuhiro, additional, Taniguchi, Itsuki, additional, Nakamura, Keiji, additional, Hayashi, Tetsuya, additional, Katayama, Takane, additional, Uemura, Tadashi, additional, and Hattori, Yukako, additional

Published
2023
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6. Identification of Core Yeast Species and Microbe-Microbe Interactions Impacting Larval Growth of Drosophila in the Wild

Author

Mure, Ayumi, primary, Sugiura, Yuki, additional, Maeda, Rae, additional, Honda, Kohei, additional, Sakurai, Nozomu, additional, Takahashi, Yuuki, additional, Watada, Masayoshi, additional, Katoh, Toshihiko, additional, Gotoh, Aina, additional, Gotoh, Yasuhiro, additional, Taniguchi, Itsuki, additional, Nakamura, Keiji, additional, Hayashi, Tetsuya, additional, Katayama, Takane, additional, Uemura, Tadashi, additional, and Hattori, Yukako, additional

Published
2023
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7. Identification of Key Yeast Species and Microbe-Microbe Interactions Impacting Larval Growth ofDrosophilain the Wild

Author

Mure, Ayumi, primary, Sugiura, Yuki, additional, Maeda, Rae, additional, Honda, Kohei, additional, Sakurai, Nozomu, additional, Takahashi, Yuuki, additional, Watada, Masayoshi, additional, Katoh, Toshihiko, additional, Gotoh, Aina, additional, Gotoh, Yasuhiro, additional, Taniguchi, Itsuki, additional, Nakamura, Keiji, additional, Hayashi, Tetsuya, additional, Katayama, Takane, additional, Uemura, Tadashi, additional, and Hattori, Yukako, additional

Published
2023
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11. Beta-2 microglobulin is a strong prognostic factor in patients with DLBCL receiving R-CHOP therapy

Author

Miyashita, Kazuho, Tomita, Naoto, Taguri, Masataka, Suzuki, Taisei, Ishiyama, Yasufumi, Ishii, Yoshimi, Nakajima, Yuki, Numata, Ayumi, Hattori, Yukako, Yamamoto, Wataru, Miyazaki, Takuya, Tachibana, Takayoshi, Takasaki, Hirotaka, Matsumoto, Kenji, Hashimoto, Chizuko, Takemura, Sachiya, Yamazaki, Etsuko, Fujimaki, Katsumichi, Sakai, Rika, Motomura, Shigeki, and Ishigatsubo, Yoshiaki

Published
2015
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16. Absolute monocyte count in follicular lymphoma patients treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

Author

Watanabe, Reina, Tomita, Naoto, Kishimoto, Kumiko, Koyama, Satoshi, Ogusa, Eriko, Ishii, Yoshimi, Miyashita, Kazuho, Matsuura, Shiro, Fujisawa, Shin, Hattori, Yukako, Takasaki, Hirotaka, Fujita, Atsuko, Ohshima, Rika, Kuwabara, Hideyuki, Hashimoto, Chizuko, Fujimaki, Katsumichi, Sakai, Rika, and Ishigatsubo, Yoshiaki

Published
2013
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20. Evaluation of soluble interleukin-2 receptor and serum lactate dehydrogenase in malignant lymphoma

Author

Tomita, Naoto, Taguri, Masataka, Hashimoto, Chizuko, Takasaki, Hirotaka, Fujimaki, Katsumichi, Motomura, Shigeki, Koharazawa, Hideyuki, Takemura, Sachiya, Fujita, Hiroyuki, Yamazaki, Etsuko, Kawasaki, Rika, Taguchi, Jun, Sakai, Rika, Fujisawa, Shin, Hattori, Yukako, Kanamori, Heiwa, Yamamoto, Wataru, Harano, Hiroshi, Ogawa, Koji, and Ishigatsubo, Yoshiaki

Published
2015
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21. Re-Examination of Several ElsinoëSpecies Reported from Japan

Author

Ujat, Anysia Hedy, Ono, Tsuyoshi, Hattori, Yukako, and Nakashima, Chiharu

Abstract

AbstractElsinoëare plant pathogenic fungi that cause scabs, spotted anthracnose, and some morphological distortions on various plants, including woody plants, economically important crops, and ornamental plants. Taxonomical reexamination of Elsinoëspecies in Japan has not yet been conducted based on the modern species criteria. In this study, several Japanese isolates were reexamine based on the morphological and molecular-phylogenetic analysis of the internal transcribed spacer region (ITS), large subunit gene (LSU)m and protein-coding gene such as RNA polymerase II subunit (rpb2)and Translation elongation factor 1-alpha (tef).Japanese isolates were divided into four clades and three new species, Elsinoë hydrangeae, E. sumire,and E. tanashiensiswere proposed. One species, Sphaceloma akebiae,was transferred to the genus Elsinoë.

Published
2023
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27. 日本産ボトリオスフェリア目菌類の分類学的研究

Author

Hattori, Yukako

Abstract

Fungi in the order Botryosphaeriales include pathogens that parasitize the leaves, fruits, and branches of plants and cause various diseases. These fungi are important plant pathogens globally, as they cause fruit rot, leaf blight, and branch blight in useful trees, such as fruit trees and trees that are used for urban greening and afforestation. In Japan, many tree diseases have been reported to be associated with Botryosphaeriales, but most of the Japanese species in this order have been described based solely on their morphological characteristics, with their molecular phylogenetic positions remaining unclear, highlighting the urgent need to review the Japanese Botryosphaeriales based on new criteria that reflect molecular phylogenetic relationships. Therefore, in this study, I conducted a taxonomic study of Japanese Botryosphaeriales fungi based on their morphological characteristics, culture characteristics, molecular phylogenetic relationships, and pathogenicities.The taxonomy of the species in the genus Phyllosticta, which are parasitic on conifer(Cupressaceae) trees in Japan, was conducted based on current criteria, including morphological characteristics, culture characteristics, phylogenetic relationships, and pathogenicities. Phylogenetic analyses revealed that this genus included several clades comprising plant pathogens that were isolated from a specific host as well as clades comprising endophytic species isolated from various conifer species. Each clade was recognized as a species based on the morphological characteristics and other features. Five species of Phyllosticta sensu stricto were recognized, two of which were newly recorded in the Japanese mycoflora. Furthermore, a new combination of P. pilospora and its epitype and an epitype and ex-type strain for P. cryptomeriae were proposed.To clarify the species diversity of Lasiodiplodia in Japan, I examined 30 Japanese isolates based on their morphological characteristics, culture characteristics, and phylogenetic relationships. Phylogenetic analyses using a matrix composed of ITS, tef1-α, tub2, and rpb2 sequences revealed that these isolates were divided into 11 clades that corresponded to L. theobromae, L. brasiliensis, L. swieteniae, L. pseudotheobromae, andLasiodiplodia spp. These species were also identified based on their morphological characteristics and the optimum growth temperature of each isolate, two of which were new additions to the Japanese mycoflora. In addition, four other species (L. latispora, L.parvispora, L. ryukyuensis, and L. yaguchii) were proposed.Reexamination of Japanese species in the genus Botryosphaeria isolated from 12 plant species belonging to ten families was carried out based on their morphological characteristics and molecular and phylogenetic analyses using the tef1-α, tub2, and rpb2 protein-coding regions and the ITS region of rDNA. These Japanese isolates were divided into five clades that were identified as B. dothidea, B. qingyuanensis, B. sinensis, andBotryosphaeria sp. Among these, B. qingyuanensis and B. sinensis have recently beenadded to the Japanese mycoflora and are not host-specific. In addition, B. tenuispora isolated from Leucothoe fontanesiana and insect galls on the leaves of Aucuba japonica was proposed as a new species.Reexamination of Japanese species in the genus Neofusicoccum was carried out based on their morphological characteristics and molecular phylogenetic relationships using the ITS, rpb2, tef1-α, and tub2 regions. These Japanese isolates were divided into five clades, which were recognized as the species N. parvum, other Neofusicoccum spp., and three new species proposed in this study (N. hyperici, N. miyakoense, and N.okinawaense). In addition, Physalospora laricina, which causes shoot blight in larch, was transferred to the genus Neofusicoccum and its epitype and ex-epitype isolates were proposed.their roles as plant pathogens, endophytes, and saprophytes in ecosystems., 本文/Graduate school of Bioresources Mie University, 167p

Published
2021

28. Peripheral blood absolute lymphocyte/monocyte ratio as a useful prognostic factor in diffuse large B-cell lymphoma in the rituximab era

Author

Watanabe, Reina, Tomita, Naoto, Itabashi, Megumi, Ishibashi, Daisuke, Yamamoto, Eri, Koyama, Satoshi, Miyashita, Kazuho, Takahashi, Hiroyuki, Nakajima, Yuki, Hattori, Yukako, Motohashi, Kenji, Takasaki, Hirotaka, Ohshima, Rika, Hashimoto, Chizuko, Yamazaki, Etsuko, Fujimaki, Katsumichi, Sakai, Rika, Fujisawa, Shin, Motomura, Shigeki, and Ishigatsubo, Yoshiaki

Published
2014
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35. Comparison of Clinical Features Between Primary and Secondary Breast Diffuse Large B Cell Lymphoma: A Yokohama Cooperative Study Group for Hematology Multicenter Retrospective Study

Author

Takahashi, Hiroyuki, primary, Sakai, Rika, additional, Sakuma, Takayuki, additional, Matsumura, Ayako, additional, Miyashita, Kazuho, additional, Ishii, Yoshimi, additional, Nakajima, Yuki, additional, Numata, Ayumi, additional, Hattori, Yukako, additional, Miyazaki, Takuya, additional, Hashimoto, Chizuko, additional, Koharazawa, Hideyuki, additional, Takemura, Sachiya, additional, Taguchi, Jun, additional, Fujimaki, Katsumichi, additional, Fujita, Hiroyuki, additional, and Nakajima, Hideaki, additional

Published
2020
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40. Multidendritic sensory neurons in the adult Drosophila abdomen: origins, dendritic morphology, and segment- and age-dependent programmed cell death

Author

Sugimura Kaoru, Hattori Yukako, Sato Motohiko, Yamamoto-Kochi Misato, Tsuyama Taiichi, Fujimoto Azusa, Shimono Kohei, Usui Tadao, Kimura Ken-ichi, and Uemura Tadashi

Subjects
Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Background For the establishment of functional neural circuits that support a wide range of animal behaviors, initial circuits formed in early development have to be reorganized. One way to achieve this is local remodeling of the circuitry hardwiring. To genetically investigate the underlying mechanisms of this remodeling, one model system employs a major group of Drosophila multidendritic sensory neurons - the dendritic arborization (da) neurons - which exhibit dramatic dendritic pruning and subsequent growth during metamorphosis. The 15 da neurons are identified in each larval abdominal hemisegment and are classified into four categories - classes I to IV - in order of increasing size of their receptive fields and/or arbor complexity at the mature larval stage. Our knowledge regarding the anatomy and developmental basis of adult da neurons is still fragmentary. Results We identified multidendritic neurons in the adult Drosophila abdomen, visualized the dendritic arbors of the individual neurons, and traced the origins of those cells back to the larval stage. There were six da neurons in abdominal hemisegment 3 or 4 (A3/4) of the pharate adult and the adult just after eclosion, five of which were persistent larval da neurons. We quantitatively analyzed dendritic arbors of three of the six adult neurons and examined expression in the pharate adult of key transcription factors that result in the larval class-selective dendritic morphologies. The 'baseline design' of A3/4 in the adult was further modified in a segment-dependent and age-dependent manner. One of our notable findings is that a larval class I neuron, ddaE, completed dendritic remodeling in A2 to A4 and then underwent caspase-dependent cell death within 1 week after eclosion, while homologous neurons in A5 and in more posterior segments degenerated at pupal stages. Another finding is that the dendritic arbor of a class IV neuron, v'ada, was immediately reshaped during post-eclosion growth. It exhibited prominent radial-to-lattice transformation in 1-day-old adults, and the resultant lattice-shaped arbor persisted throughout adult life. Conclusion Our study provides the basis on which we can investigate the genetic programs controlling dendritic remodeling and programmed cell death of adult neurons, and the life-long maintenance of dendritic arbors.

Published
2009
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41. Divergence of Drosophila species: Longevity and reproduction under different nutrient balances.

Author

Watada, Masayoshi, Hayashi, Yusaku, Watanabe, Kaori, Mizutani, Shoko, Mure, Ayumi, Hattori, Yukako, and Uemura, Tadashi

Subjects
DROSOPHILA, LIFE spans, LONGEVITY, REPRODUCTION, SEXUAL dimorphism
Abstract

How nutrition impacts growth, reproduction and longevity is complex because relationships between these life events are difficult to disentangle. As a first step in sorting out these processes, we carried out a comparative analysis of related species of Drosophila with distinct feeding habits. In particular, we examined life spans and egg laying of two generalists and three specialists on diets with distinct protein‐to‐carbohydrate ratios. In contrast to the generalist D. melanogaster, adult males of two specialists, D. sechellia and D. elegans, lived longer on a protein‐rich diet. These results and our previous studies collectively show that the diet to which larvae of each specialist species have adapted ensures a longer life span of adult males of that same species. We also found a species‐specific sexual dimorphism of life span in the above two specialists regardless of the diets, which was in sharp contrast to D. melanogaster. In D. melanogaster, males lived longer than females, whereas females of D. sechellia and D. elegans were longer‐lived than males, and those specialist females were exceedingly low in egg production, relative to the other species. We discuss our findings from perspectives of mechanisms, including a possible contribution of egg production to life span. [ABSTRACT FROM AUTHOR]

Published
2020
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42. Primary uterine lymphoma: The Yokohama Cooperative Study Group for Hematology (YACHT) study

Author

Ishii, Yoshimi, primary, Fujisawa, Shin, additional, Ando, Taiki, additional, Suzuki, Taisei, additional, Ishiyama, Yasufumi, additional, Kishimoto, Kumiko, additional, Hattori, Yukako, additional, Nakajima, Yuki, additional, Miyazaki, Takuya, additional, Takasaki, Hirotaka, additional, Matsumoto, Kenji, additional, Koharazawa, Hideyuki, additional, Taguchi, Jun, additional, Fujimaki, Katsumichi, additional, Sakai, Rika, additional, and Nakajima, Hideaki, additional

Published
2018
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44. Taxonomical Study of Noteworthy Species of Botryosphaeriain Japan

Author

Hattori, Yukako, Ando, Yuho, Sasaki, Atsuko, Uechi, Nami, and Nakashima, Chiharu

Abstract

AbstractThe reexamination of the fungal genus Botryosphaeriaon 12 plant species of 10 families was carried out based on molecular phylogenetic analyses using the regions of translation elongation factor 1-α, β-tubulin, DNA-directed RNA polymerase II subunit, and internal transcribed spacer region of rDNA and morphological characteristics. Japanese isolates were divided into five clades and include Botryosphaeria dothidea, B. qingyuanensis, B. sinensis, and Botryosphaeriaspp. Two species, B. qingyuanensisand B. sinensishave been newly added to the Japanese mycoflora, but their host plants are not specified. Botryosphaeria tenuisporaisolated from Leucothoe fontanesianaand insect galls on fruits of Aucuba japonicahas been proposed as a new species.

Published
2021
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47. Septicemia from Lactobacillus rhamnosus GG, from a Probiotic Enriched Yogurt, in a Patient with Autologous Stem Cell Transplantation.

Author

Koyama, Satoshi, Fujita, Hiroyuki, Shimosato, Takeshi, Kamijo, Aki, Ishiyama, Yasufumi, Yamamoto, Eri, Ishii, Yoshimi, Hattori, Yukako, Hagihara, Maki, Yamazaki, Etsuko, Tomita, Naoto, and Nakajima, Hideaki

Abstract

Probiotic-rich foods are consumed without much restriction. We report here, a case of septic shock caused by yogurt derived Lactobacillus species in a 54-year-old male patient with acute promyelocytic leukemia, in second complete remission, and who was an autologous stem cell transplantation recipient. He received high dose chemotherapy and autologous peripheral blood stem cell transplantation. He ingested commercially available probiotic-enriched yogurt because of severe diarrhea. One week later, he developed septic shock, and the pathogen was determined by strain-specific PCR analysis as Lactobacillus rhamnosus GG (ATCC 53103), which was found to be identical with the strain in the yogurt he consumed. Thus, because even low virulent Lactobacilli in the probiotic products can be pathogenic in the compromised hosts, ingestion of such products should be considered with caution in neutropenic patients with severe diarrhea, such as stem cell transplantation recipients. [ABSTRACT FROM AUTHOR]

Published
2019
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48. ショウジョウバエ感覚神経の樹状突起形態形成を制御するサブタイプ特異的な有糸分裂後転写プログラム

Author

Hattori, Yukako, 上村, 匡, 西田, 栄介, and 荒木, 崇

Subjects
sensory neuron, differentiation, neuronal subtype, transcription factor, dendrite
Abstract

Yukako Hattori, Tadao Usui, Daisuke Satoh, Sanefumi Moriyama, Kohei Shimono, Takehiko Itoh, Katsuhiko Shirahige, Tadashi Uemura, Sensory-Neuron Subtype-Specific Transcriptional Programs Controlling Dendrite Morphogenesis: Genome-wide Analysis of Abrupt and Knot/Collier, Developmental Cell, Volume 27, Issue 5, 9 December 2013, Pages 530-544, ISSN 1534-5807

Published
2014

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