Search

Your search keyword '"Hauffe, Pia"' showing total 4 results
Start Over Author "Hauffe, Pia"
4 results on '"Hauffe, Pia"'

3. Perzentilen für linksventrikuläre Rotation und Vergleich mit schrittmacherinduzierten Dysssynchronien

Author

Hauffe, Pia

Subjects
Torsion, Herzschrittmacher, Herzfehler, Rotation, ddc:610, Ultraschallkardiografie
Abstract

Ziel dieses Projektes war die Referenzwerterstellung für echokardiografische Parameter zur Quantifizierung der linksventrikulären Rotationsbewegung bei Kindern mit einem großen Probandenkollektiv. Es wurden 174 gesunde Probanden zwischen 0-20 Jahren mit 2D Speckle Tracking untersucht und Rotations- und Torsions- Perzentilen hergestellt. Diese Werte wurden mit 42 Schrittmacherpatienten verglichen. Die maximale Torsion normalisiert auf die LV-Länge war erhöht in der frühen Kindheit und verringerte sich bis zum Erwachsenenalter. Die apikale Rotation zeigte eine große Bandbreite, während die basale Rotation durch alle Altersklassen konstant blieb. Die TTP-Zeiten zwischen apikaler und basaler Rotation waren in der frühen Kindheit größer, während sie beim Erwachsenen kleiner ausfielen. Schrittmacher-Patienten hatten eine geringere maximale Torsion, sowie apikale und basale Rotation. Sowohl die Dyssynchronie-Indices als auch die EF korrelierten mit der maximalen Torsion.

Published
2017

4. Percentiles for left ventricular rotation: comparison of reference values to paediatric patients with pacemaker-induced dyssynchrony.

Author

Laser KT, Hauffe P, Haas NA, Körperich H, Faber L, Peters B, Fischer M, and Kececioglu D

Subjects
Adolescent, Child, Child, Preschool, Echocardiography, Female, Humans, Infant, Infant, Newborn, Male, Reference Values, Rotation, Young Adult, Torsion, Mechanical, Ventricular Function, Left physiology
Abstract

Aim: Left ventricular rotation is an interesting mechanism to investigate patients with heart disease. In children, reference values have to be defined prior to assess pathology., Methods and Results: One hundred and seventy-four healthy individuals (0-20 years) were investigated by two-dimensional speckle tracking echocardiography, percentiles were created addressing the amount and time-to-peak values (TTP) of rotational parameters normalized to percentage of cardiac cycle (cc). Patients with right ventricular (RV) pacemaker stimulation were integrated into percentiles describing their rotational delay. Feasibility was 87.4% in healthy individuals (8.5 ± 6.2 years), 42 patients (13.0 ± 6.6 years, mean RV-stimulation time: 6.1 ± 4.3 years) were enrolled. Apical rotation (Rot(ap)) varied and was higher than basal rotation (Rot(bas)) throughout all ages. Peak torsion (Tor(max)) normalized to left ventricle (LV) length (Tor(maxi)) was elevated in early childhood and decreased until adulthood. TTP values revealed greater dispersion between apical and basal rotation at younger age and a decrease during maturation. Patients with RV pacing had decreased Tor(max) (10.0 ± 6.0 vs. 13.7 ± 6.6°, P < 0.05), Rot(ap) (6.7 ± 4.8 vs. 9.3 ± 5.7°, P < 0.05) and Rot(bas) (-3.3 ± 2.6 vs. -4.5 ± 2.7°, P < 0.05). Patients with impaired ejection fraction (EF) had abnormal delays between Rot(ap) and Rot(bas)., Conclusions: Percentile illustrations of LV rotation reveal a high amount and dispersion of Rot(ap) and Tor(maxi) in young children as well as a higher rotational delay compared with older ages. Abnormal delays in RV pacing are associated with reduced EF., (Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2014. For permissions please email: journals.permissions@oup.com.)

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results