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Digital Image Correlation (DIC) has been widely used as a non-contact deformation measurement technique. Nevertheless, its accuracy is greatly affected by the speckle pattern on the specimen. To systematically evaluate how speckle deformability affects the precision of DIC algorithms. In this study, a test dataset of 2D speckle patterns with various prescribed deformation fields was numerically generated, containing two categories of speckles, i.e., the deformable and the non-deformable (rigid) ones. This dataset was used to evaluate the performance of inverse compositional Gauss-Newton (ICGN)-based DIC algorithms with two types of shape function (first-order and second-order), in the different scenarios of the deformation field. The results showed that imaging noise had a significant influence on the DIC algorithm. The first-order shape function (ICGN-1) performed better when tracking the simple linear deformation field. While the second-order shape function (ICGN-2) was proved to perform better on non-linear deformations. Moreover, the deformability of the speckle was found to have an obvious impact on the performance of the DIC algorithm. ICGN-2 could effectively reduce so-called speckle rigidity induced (SRI) error. Conclusively, ICGN-2 should be chosen as priority, because of its feasibility on non-linear deformation fields and speckle rigidity. While in the linear deformation scenarios, ICGN-1 was still a robust and efficient method.

Abstract Computational fluid dynamics (CFD) simulations are increasingly utilised to evaluate intracranial aneurysm (IA) haemodynamics to aid in the prediction of morphological changes and rupture risk. However, these models vary and differences in published results warrant the investigation of IA-CFD reproducibility. This study aims to explore sources of intra-team variability and determine its impact on the aneurysm morphology and CFD parameters. A team of four operators were given six sets of magnetic resonance angiography data spanning a decade from one patient with a middle cerebral aneurysm. All operators were given the same protocol and software for model reconstruction and numerical analysis. The morphology and haemodynamics of the operator models were then compared. The segmentation, smoothing factor, inlet and outflow branch lengths were found to cause intra-team variability. There was 80% reproducibility in the time-averaged wall shear stress distribution among operators with the major difference attributed to the level of smoothing. Based on these findings, it was concluded that the clinical applicability of CFD simulations may be feasible if a standardised segmentation protocol is developed. Moreover, when analysing the aneurysm shape change over a decade, it was noted that the co-existence of positive and negative values of the wall shear stress divergence (WSSD) contributed to the growth of a daughter sac.