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1. Abstract GS4-07: Race, ethnicity and clinical outcomes in hormone receptor-positive, HER2-negative, node-negative breast cancer: results from the TAILORx trial

Author

Albain, K, primary, Gray, RJ, additional, Sparano, JA, additional, Makower, DF, additional, Pritchard, KI, additional, Hayes, DF, additional, Geyer, CE, additional, Dees, EC, additional, Goetz, MP, additional, Olson, JA, additional, Lively, T, additional, Badve, SS, additional, Saphner, TJ, additional, Wagner, LI, additional, Whelan, TJ, additional, Ellis, MJ, additional, Paik, S, additional, Wood, WC, additional, Ravdin, PM, additional, Keane, MM, additional, Gomez, HL, additional, Reddy, PS, additional, Goggins, TF, additional, Mayer, IA, additional, Brufsky, AM, additional, Toppmeyer, DL, additional, Kaklamani, VG, additional, Berenberg, JL, additional, Abrams, J, additional, and Sledge, GW, additional

Published
2019
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2. Abstract P4-02-01: Analytical validation of an automated digital scoring protocol for Ki67: International multicenter collaboration study

Author

Acs, B, primary, Leung, SC, additional, Pelekanou, V, additional, Bai, Y, additional, Martinez-Morilla, S, additional, Toki, M, additional, Chang, MC, additional, Gholap, A, additional, Jadhav, A, additional, Hugh, JC, additional, Bigras, G, additional, Laurinavicius, A, additional, Augulis, R, additional, Levenson, R, additional, Todd, A, additional, Piper, T, additional, Virk, S, additional, van der Vegt, B, additional, Hayes, DF, additional, Dowsett, M, additional, Nielsen, TO, additional, and Rimm, DL, additional

Published
2019
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3. Abstract PD9-12: Integrative molecular profiling of breast cancer brain metastasis and patient-derived xenograft organoids from resected breast cancer brain metastases to interrogate and prioritize therapeutic personalized strategies

Author

Morikawa, A, primary, Robinson, DR, additional, Soellner, M, additional, Wu, Y-M, additional, Lonigro, R, additional, Gilani, R, additional, Cheng, X, additional, Lachacz, E, additional, Thomas, D, additional, McMurray, K, additional, Smerage, J, additional, Henry, NL, additional, Heth, J, additional, Chinnaiyan, A, additional, Hayes, DF, additional, and Merajver, S, additional

Published
2019
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4. Abstract P4-08-06: Impact of molecular subtypes on long-term outcomes in triple-negative breast cancer (TNBC) patients treated with adjuvant AC chemotherapy on SWOG S9313

Author

Sharma, P, primary, Barlow, WB, additional, Hout, DR, additional, Seitz, RS, additional, Bailey, DB, additional, Godwin, AK, additional, Pathak, H, additional, Timms, KM, additional, Solimeno, C, additional, Linden, HM, additional, Porter, P, additional, Tripathy, D, additional, Hortobagyi, GN, additional, Thompson, A, additional, Pusztai, L, additional, and Hayes, DF, additional

Published
2019
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5. 20-year risks of breast-cancer recurrence after stopping endocrine therapy at 5 years

Author

Pan, H, Gray, R, Braybrooke, J, Davies, C, Taylor, C, Mcgale, P, Peto, R, Pritchard, Ki, Bergh, J, Dowsett, M, Hayes, Df, Albain, K, Anderson, S, Arriagada, R, Barlow, W, Bartlett, J, Bergsten‐nordström, E, Bliss, J, Boccardo, F, Bradley, R, Brain, E, Cameron, D, Clarke, M, Coates, A, Coleman, R, Correa, C, Costantino, J, Cuzick, J, Davidson, N, Dodwell, D, Di Leo, A, Ewertz, M, Forbes, J, Gelber, R, Gnant, M, Goldhirsch, A, Goodwin, P, Hill, C, Ingle, J, Jagsi, R, Janni, W, Loibl, S, Mackinnon, E, Martin, M, Mukai, H, Norton, L, Ohashi, Y, Paik, S, Perez, E, Piccart, M, Pierce, L, Poortmans, P, Raina, V, Ravdin, P, Regan, M, Robertson, J, Rutgers, E, Slamon, D, Sparano, J, Swain, S, Tutt, A, Viale, G, Von Minckwitz, G, Wang, X, Whelan, T, Wilcken, N, Winer, E, Wolmark, N, Wood, W, Zambetti, M, Alberro, Ja, Ballester, B, Deulofeu, P, Fábregas, R, Fraile, M, Gubern, Jm, Janer, J, Moral, A, De Pablo Jl, Peñalva, G, Puig, P, Ramos, M, Rojo, R, Santesteban, P, Serra, C, Solà, M, Solarnau, L, Solsona, J, Veloso, E, Vidal, S, Abe, O, Abe, R, Enomoto, K, Kikuchi, K, Koyama, H, Masuda, H, Nomura, Y, Sakai, K, Sugimachi, K, Toi, M, Tominaga, T, Uchino, J, Yoshida, M, Haybittle, Jl, Leonard, Cf, Calais, G, Garaud, P, Collett, V, Delmestri, A, Sayer, J, Harvey, Vj, Holdaway, Im, Kay, Rg, Mason, Bh, Forbes, Jf, Balic, M, Bartsch, R, Fesl, C, Fitzal, F, Fohler, H, Greil, R, Jakesz, R, Marth, C, Mlineritsch, B, Pfeiler, G, Singer, Cf, Steger, Gg, Stöger, H, Canney, P, Yosef, Hma, Focan, C, Peek, U, Oates, Gd, Powell, J, Durand, M, Mauriac, L, Dolci, S, Larsimont, D, Nogaret, Jm, Philippson, C, Piccart, Mj, Masood, Mb, Parker, D, Price, Jj, Lindsay, Ma, Mackey, J, Hupperets, Psgj, Bates, T, Blamey, Rw, Chetty, U, Ellis, Io, Mallon, E, Morgan, Dal, Patnick, J, Pinder, S, Lohrisch, C, Nichol, A, Bramwell, Vh, Chen, Be, Gelmon, K, Goss, Pe, Levine, Mn, Parulekar, W, Pater, Jl, Shepherd, Le, Tu, D, Berry, D, Broadwater, G, Cirrincione, C, Muss, H, Weiss, Rb, Abu‐zahra, Ht, Portnoj, Sm, Bowden, S, Brookes, C, Dunn, J, Fernando, I, Lee, M, Poole, C, Rea, D, Spooner, D, Barrett‐lee, Pj, Mansel, Re, Monypenny, Ij, Gordon, Nh, Davis, Hl, Sestak, I, Lehingue, Y, Romestaing, P, Dubois, Jb, Delozier, T, Griffon, B, Mace Lesec’h, J, De La Lande, B, Mouret‐fourme, E, Mustacchi, G, Petruzelka, L, Pribylova, O, Owen, Jr, Harbeck, N, Jänicke, F, Meisner, C, Schmitt, M, Thomssen, C, Meier, P, Shan, Y, Shao, Yf, Zhao, Db, Chen, Zm, Howell, A, Swindell, R, Boddington, C, Burrett, Ja, Cutter, D, Duane, F, Evans, V, Gettins, L, Godwin, J, James, S, Kerr, A, Liu, H, Mannu, G, Mchugh, T, Morris, P, Read, S, Wang, Y, Wang, Z, Albano, J, De Oliveira Cf, Gervásio, H, Gordilho, J, Ejlertsen, B, Jensen, Mb, Johansen, H, Mouridsen, H, Palshof, T, Gelman, Rs, Harris, Jr, Henderson, C, Shapiro, Cl, Christiansen, P, Mouridsen, Ht, Fehm, T, Trampisch, Hj, Dalesio, O, De Vries Ege, Rodenhuis, S, Van Tinteren, H, Comis, Rl, Davidson, Ne, Robert, N, Sledge, G, Solin, Lj, Sparano, Ja, Tormey, Dc, Dixon, Jm, Forrest, P, Jack, W, Kunkler, I, Rossbach, J, Klijn, Jgm, Treurniet‐donker, Ad, Van Putten Wlj, Rotmensz, N, Veronesi, U, Bartelink, H, Bijker, N, Bogaerts, J, Cardoso, F, Cufer, T, Julien, Jp, Van De Velde Cjh, Cunningham, Mp, Brufsky, Am, Coleman, Re, Llombart, Ha, Huovinen, R, Joensuu, H, Costa, A, Bonadonna, G, Gianni, L, Valagussa, P, Goldstein, Lj, Bonneterre, J, Fargeot, P, Fumoleau, P, Kerbrat, P, Luporsi, E, Namer, M, Carrasco, E, Segui, Ma, Eiermann, W, Hilfrich, J, Jonat, W, Kaufmann, M, Kreienberg, R, Schumacher, M, Bastert, G, Rauschecker, H, Sauer, R, Sauerbrei, W, Schauer, A, Blohmer, Ju, Costa, Sd, Eidtmann, H, Gerber, B, Jackisch, C, De Schryver, A, Vakaet, L, Belfiglio, M, Nicolucci, A, Pellegrini, F, Pirozzoli, Mc, Sacco, M, Valentini, M, Mcardle, Cs, Smith, Dc, Stallard, S, Dent, Dm, Gudgeon, Ca, Hacking, A, Murray, E, Panieri, E, Werner, Id, Galligioni, E, Leone, B, Vallejo, Ct, Zwenger, A, Lopez, M, Erazo, A, Medina, Jy, Horiguchi, J, Takei, H, Fentiman, Is, Hayward, Jl, Rubens, Rd, Skilton, D, Scheurlen, H, Sohn, Hc, Untch, M, Dafni, U, Markopoulos, C, Fountzilas, G, Mavroudis, D, Klefstrom, P, Blomqvist, C, Saarto, T, Gallen, M, Tinterri, C, Margreiter, R, De Lafontan, B, Mihura, J, Roché, H, Asselain, B, Salmon, Rj, Vilcoq, Jr, André, F, Delaloge, S, Koscielny, S, Michiels, S, Rubino, C, A'Hern, R, Ellis, P, Kilburn, L, Yarnold, Jr, Benraadt, J, Kooi, M, Van De Velde Ao, Van Dongen Ja, Vermorken, Jb, Castiglione, M, Colleoni, M, Collins, J, Gelber, Rd, Lindtner, J, Price, Kn, Regan, Mm, Rudenstam, Cm, Senn, Hj, Thuerlimann, B, Bliss, Jm, Chilvers, Ced, Coombes, Rc, Hall, E, Marty, M, Buyse, M, Possinger, K, Schmid, P, Wallwiener, D, Bighin, C, Bruzzi, P, Del Mastro, L, Dozin, B, Pastorino, S, Pronzato, P, Sertoli, Mr, Foster, L, George, Wd, Stewart, Hj, Stroner, P, Borovik, R, Hayat, H, Inbar, Mj, Peretz, T, Robinson, E, Camerini, T, Formelli, F, Martelli, G, Di Mauro Mg, Perrone, F, Amadori, D, Martoni, A, Pannuti, F, Camisa, R, Musolino, A, Passalacqua, R, Iwata, H, Shien, T, Ikeda, T, Inokuchi, K, Sawa, K, Sonoo, H, Sadoon, M, Tulusan, Ah, Kohno, N, Miyashita, M, Takao, S, Ahn, Jh, Jung, Kh, Korzeniowski, S, Skolyszewski, J, Ogawa, M, Yamashita, J, Bastiaannet, E, Liefers, Gj, Christiaens, R, Neven, P, Paridaens, R, Van Den Bogaert, W, Braun, S, Martin, P, Romain, S, Janauer, M, Seifert, M, Sevelda, P, Zielinski, Cc, Hakes, T, Hudis, Ca, Wittes, R, Giokas, G, Kondylis, D, Lissaios, B, De La Huerta, R, Sainz, Mg, Ro, J, Camphausen, K, Danforth, D, Lichter, A, Lippman, M, Smart, D, Steinberg, S, D’Amico, C, Lioce, M, Paradiso, A, Ohno, S, Bass, G, Brown, A, Bryant, J, Dignam, J, Fisher, B, Geyer, C, Mamounas, Ep, Redmond, C, Wickerham, L, Aihara, T, Hozumi, Y, Baum, M, Jackson, Im, Palmer, Mk, Ingle, Jn, Suman, Vj, Bengtsson, No, Emdin, S, Jonsson, H, Venturini, M, Lythgoe, Jp, Kissin, M, Erikstein, B, Hannisdal, E, Jacobsen, Ab, Reinertsen, Kv, Varhaug, Je, Gundersen, S, Hauer‐jensen, M, Høst, H, Nissen‐meyer, R, Mitchell, Ak, Robertson, Jfr, Ueo, H, Di Palma, M, Mathé, G, Misset, Jl, Levine, M, Morimoto, K, Takatsuka, Y, Crossley, E, Harris, A, Talbot, D, Taylor, M, Cocconi, G, Di Blasio, B, Ivanov, V, Paltuev, R, Semiglazov, V, Brockschmidt, J, Cooper, Mr, Falkson, Ci, Hadji, P, A’Hern, R, Makris, A, Parton, M, Pennert, K, Powles, Tj, Smith, Ie, Gazet, Jc, Browne, L, Graham, P, Corcoran, N, Clack, G, Van Poznak, C, Deshpande, N, Di Martino, L, Douglas, P, Lindtner, A, Notter, G, Bryant, Ajs, Ewing, Gh, Firth, La, Krushen‐kosloski, Jl, Anderson, H, Killander, F, Malmström, P, Rydén, L, Arnesson, Lg, Carstensen, J, Dufmats, M, Fohlin, H, Nordenskjöld, B, Söderberg, M, Carpenter, Jt, Murray, N, Royle, Gt, Simmonds, Pd, Crowley, J, Gralow, J, Hortobagyi, G, Livingston, R, Martino, S, Osborne, Ck, Ravdin, Pm, Bondesson, T, Celebioglu, F, Dahlberg, K, Fornander, T, Fredriksson, I, Frisell, J, Göransson, E, Iiristo, M, Johansson, U, Lenner, E, Löfgren, L, Nikolaidis, P, Perbeck, L, Rotstein, S, Sandelin, K, Skoog, L, Svane, G, Af Trampe, E, Wadström, C, Maibach, R, Thürlimann, B, Holli, K, Rouhento, K, Safra, T, Brenner, H, Hercbergs, A, Yoshimoto, M, Paterson, Ahg, Fyles, A, Meakin, Jw, Panzarella, T, Bahi, J, Lemonnier, J, Martin, Al, Reid, M, Spittle, M, Bishop, H, Bundred, Nj, Forsyth, S, Pinder, Se, Deutsch, Gp, Kwong, Dlw, Pai, Vr, Senanayake, F, Rubagotti, A, Hackshaw, A, Houghton, J, Ledermann, J, Monson, K, Tobias, Js, Carlomagno, C, De Laurentiis, M, De Placido, S, Williams, L, Bell, R, Hinsley, S, Marshall, Hc, Pierce, Lj, Solomayer, E, Horsman, Jm, Lester, J, Winter, Mc, Buzdar, Au, Hsu, L, Love, Rr, Ahlgren, J, Garmo, H, Holmberg, L, Liljegren, G, Lindman, H, Wärnberg, F, Asmar, L, Jones, Se, Aft, R, Gluz, O, Liedtke, C, Nitz, U, Litton, A, Wallgren, A, Karlsson, P, Linderholm, Bk, Chlebowski, Rt, Caffier, H., Guided Treatment in Optimal Selected Cancer Patients (GUTS), Other departments, CCA - Cancer Treatment and Quality of Life, Radiotherapy, Pan, Hongchao, Gray, Richard, Braybrooke, Jeremy, Davies, Christina, Taylor, Carolyn, Mcgale, Paul, Peto, Richard, Pritchard, Kathleen I, Bergh, Jona, Dowsett, Mitch, Hayes, Daniel F, De Laurentiis, Michelino, MUMC+: MA Medische Oncologie (9), RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, and Interne Geneeskunde

Subjects
0301 basic medicine, Oncology, medicine.medical_treatment, Kaplan-Meier Estimate, law.invention, 0302 clinical medicine, Randomized controlled trial, law, Recurrence, Receptors, Neoplasm Metastasis, AMERICAN SOCIETY, Adjuvant, CLINICAL-PRACTICE GUIDELINE, Absolute risk reduction, Estrogen Antagonists, General Medicine, Estrogen Antagonist, CHEMOTHERAPY, Middle Aged, Prognosis, Neoplasm Metastasi, Local, POSTMENOPAUSAL WOMEN, Receptors, Estrogen, Chemotherapy, Adjuvant, 030220 oncology & carcinogenesis, Meta-analysis, Lymphatic Metastasis, Female, Human, Estrogen Antagonists/therapeutic use, Adult, Risk, medicine.medical_specialty, Prognosi, medicine.drug_class, DISCONTINUATION, Breast Neoplasms, Article, Drug Administration Schedule, LATE DISTANT RECURRENCE, 03 medical and health sciences, Breast cancer, Breast Neoplasms/drug therapy, Internal medicine, SCORE, medicine, Humans, SURGICAL ADJUVANT BREAST, Aged, Proportional Hazards Models, Chemotherapy, business.industry, Proportional hazards model, Lymphatic Metastasi, TAMOXIFEN THERAPY, ta3122, medicine.disease, Estrogen, RANDOMIZED-TRIALS, Discontinuation, Surgery, Neoplasm Recurrence, 030104 developmental biology, Proportional Hazards Model, Neoplasm Grading, Neoplasm Recurrence, Local, business
Abstract

Background The administration of endocrine therapy for 5 years substantially reduces recurrence rates during and after treatment in women with early-stage, estrogen-receptor (ER)–positive breast cancer. Extending such therapy beyond 5 years offers further protection but has additional side effects. Obtaining data on the absolute risk of subsequent distant recurrence if therapy stops at 5 years could help determine whether to extend treatment. Methods In this meta-analysis of the results of 88 trials involving 62,923 women with ER-positive breast cancer who were disease-free after 5 years of scheduled endocrine therapy, we used Kaplan–Meier and Cox regression analyses, stratified according to trial and treatment, to assess the associations of tumor diameter and nodal status (TN), tumor grade, and other factors with patients’ outcomes during the period from 5 to 20 years. Results Breast-cancer recurrences occurred at a steady rate throughout the study period from 5 to 20 years. The risk of distant recurrence was strongly correlated with the original TN status. Among the patients with stage T1 disease, the risk of distant recurrence was 13% with no nodal involvement (T1N0), 20% with one to three nodes involved (T1N1–3), and 34% with four to nine nodes involved (T1N4–9); among those with stage T2 disease, the risks were 19% with T2N0, 26% with T2N1–3, and 41% with T2N4–9. The risk of death from breast cancer was similarly dependent on TN status, but the risk of contralateral breast cancer was not. Given the TN status, the factors of tumor grade (available in 43,590 patients) and Ki-67 status (available in 7692 patients), which are strongly correlated with each other, were of only moderate independent predictive value for distant recurrence, but the status regarding the progesterone receptor (in 54,115 patients) and human epidermal growth factor receptor type 2 (HER2) (in 15,418 patients in trials with no use of trastuzumab) was not predictive. During the study period from 5 to 20 years, the absolute risk of distant recurrence among patients with T1N0 breast cancer was 10% for low-grade disease, 13% for moderate-grade disease, and 17% for high-grade disease; the corresponding risks of any recurrence or a contralateral breast cancer were 17%, 22%, and 26%, respectively. Conclusions After 5 years of adjuvant endocrine therapy, breast-cancer recurrences continued to occur steadily throughout the study period from 5 to 20 years. The risk of distant recurrence was strongly correlated with the original TN status, with risks ranging from 10 to 41%, depending on TN status and tumor grade. (Funded by Cancer Research UK and others.)

Published
2017

6. Abstract PD5-07: A phase III randomized trial of anastrozole and fulvestrant versus anastrozole or sequential anastrozole and fulvestrant as first-line therapy for postmenopausal women with metastatic breast cancer: Final survival outcomes of SWOG S0226

Author

Mehta, RS, primary, Barlow, WE, additional, Albain, KS, additional, Vandenberg, TA, additional, Dakhil, SR, additional, Tirumali, NL, additional, Lew, DL, additional, Hayes, DF, additional, Gralow, JR, additional, Linden, HM, additional, Livingston, RB, additional, and Hortobagyi, GN, additional

Published
2018
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7. Abstract P2-09-26: Frequency and mechanisms of elevated somatic mutation burden in metastatic breast cancer and response to immune checkpoint blockade

Author

Cobain, EF, primary, Robinson, DR, additional, Wu, Y-M, additional, Lonigro, R, additional, Vats, P, additional, Rabban, E, additional, Kumar-Sinha, C, additional, Schott, AF, additional, Smerage, JB, additional, Morikawa, A, additional, Burness, ML, additional, Van Poznak, CH, additional, Griggs, J, additional, Wicha, M, additional, Hayes, DF, additional, and Chinnaiyan, AM, additional

Published
2018
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8. Abstract P2-03-01: Analytical validation of a standardized scoring protocol for Ki67 assessed on breast excision whole sections: An international multicenter collaboration

Author

Nielsen, TO, primary, Leung, SCY, additional, Zabaglo, LA, additional, Arun, I, additional, Badve, SS, additional, Bane, AL, additional, Bartlet, JMS, additional, Borgquist, S, additional, Chang, MC, additional, Dodson, A, additional, Ehinger, A, additional, Fineberg, S, additional, Focke, CM, additional, Gao, D, additional, Gown, AM, additional, Gutierrez, C, additional, Hugh, JC, additional, Kos, Z, additional, Lænkholm, A-V, additional, Mastropasqua, MG, additional, Moriya, T, additional, Nofech-Mozes, S, additional, Osborne, CK, additional, Penault-Llorca, FM, additional, Piper, T, additional, Sakatani, T, additional, Salgado, R, additional, Starczynski, J, additional, Sugie, T, additional, van der Vegt, B, additional, Viale, G, additional, Hayes, DF, additional, McShane, LM, additional, and Dowsett, M, additional

Published
2018
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9. Abstract P1-09-05: Radiosensitization of androgen receptor (AR)-positive triple-negative breast cancer (TNBC) cells using seviteronel (INO-464), a selective CYP17 lyase and AR inhibitor

Author

Speers, CW, primary, Chandler, B, additional, Olsen, E, additional, Wilder-Romans, K, additional, Moubadder, L, additional, Nyati, S, additional, Rae, J, additional, Hayes, DF, additional, Spratt, DE, additional, Wahl, DR, additional, Eisner, J, additional, Feng, FY, additional, and Pierce, LJ, additional

Published
2018
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10. Abstract P1-03-01: An international multicenter study to evaluate reproducibility of automated scoring methods for assessment of Ki67 in breast cancer

Author

Rimm, DL, primary, McShane, LM, additional, Leung, SCY, additional, Bai, Y, additional, Bane, AL, additional, Bartlett, JMS, additional, Bayani, J, additional, Chang, MC, additional, Dean, M, additional, Denkert, C, additional, Enwere, E, additional, Galderisi, C, additional, Gholap, A, additional, Hugh, JC, additional, Jadhav, A, additional, Kornaga, E, additional, Laurinavicius, A, additional, Levenson, R, additional, Lima, J, additional, Miller, K, additional, Pantanowitz, L, additional, Piper, T, additional, Ruan, J, additional, Srinivasan, M, additional, Virk, S, additional, Wu, Y, additional, Yang, H, additional, Hayes, DF, additional, Nielsen, TO, additional, and Dowsett, M, additional

Published
2017
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12. Abstract PD7-07: Discovery of molecular predictors of late breast cancer specific events (BCSE) in ER+, node+ breast cancer – new transcriptome expression whole gene analysis of the phase III adjuvant trial SWOG S8814

Author

Albain, KS, primary, Crager, MR, additional, Barlow, WE, additional, Baehner, FL, additional, Bergamaschi, A, additional, Rae, JM, additional, Ravdin, PM, additional, Tripathy, D, additional, Gralow, JR, additional, Livingston, RB, additional, Osborne, CK, additional, Ingle, JN, additional, Pritchard, KI, additional, Davidson, NE, additional, Carey, LA, additional, Cherbavaz, DB, additional, Sing, AP, additional, Shak, S, additional, Hortobagyi, GN, additional, and Hayes, DF, additional

Published
2017
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15. Abstract P1-01-01: Circulating tumor cell number and CTC-endocrine therapy index predict clinical outcomes in ER positive metastatic breast cancer patients: Results of the COMETI Phase 2 trial

Author

Paoletti, C, primary, Regan, MM, additional, Liu, MC, additional, Marcom, PK, additional, Hart, LL, additional, Smith, JW, additional, Tedesco, KL, additional, Amir, E, additional, Krop, IE, additional, DeMichele, AM, additional, Goodwin, PJ, additional, Block, M, additional, Aung, K, additional, Cannell, EM, additional, Darga, EP, additional, Baratta, PJ, additional, Brown, ME, additional, McCormack, RT, additional, and Hayes, DF, additional

Published
2017
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16. Abstract P5-07-01: Successful whole transcriptome analysis of 25-year-old breast tumor samples from the phase III trial SWOG-8814 by next generation sequencing (NGS): Standardized analytical methods for exploratory and validation studies

Author

Cherbavaz, DB, primary, Hayes, DF, additional, Qu, K, additional, Crager, MR, additional, Barlow, WR, additional, Goddard, AD, additional, Beasley, EM, additional, Jeong, J, additional, Collin, F, additional, Liu, M-L, additional, Rae, JM, additional, Ravdin, PM, additional, Tripathy, D, additional, Gralow, JR, additional, Livingston, RB, additional, Osborne, CK, additional, Ingle, JN, additional, Pritchard, KI, additional, Davidson, NE, additional, Carey, LA, additional, Sing, AP, additional, Baehner, FL, additional, Hortobagyi, GN, additional, Shak, S, additional, and Albain, KS, additional

Published
2016
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17. Abstract P1-01-01: Analytical validation of a standardized scoring protocol for Ki67: Phase-3 of an international multicenter collaboration

Author

Dowsett, M, primary, Leung, SCY, additional, Zabaglo, L, additional, Arun, I, additional, Badve, SS, additional, Bane, AL, additional, Bartlett, JMS, additional, Borgquist, S, additional, Chang, MC, additional, Dodson, A, additional, Enos, RA, additional, Fineberg, S, additional, Focke, CM, additional, Gao, D, additional, Gown, AM, additional, Grabau, D, additional, Gutierrez, C, additional, Hugh, JC, additional, Kos, Z, additional, Lænkholm, A-V, additional, Lin, M-G, additional, Mastropasqua, MG, additional, Moriya, T, additional, Nofech-Mozes, S, additional, Osborne, CK, additional, Penault-Llorca, FM, additional, Piper, T, additional, Sakatani, T, additional, Salgado, R, additional, Starczynski, J, additional, Viale, G, additional, Hayes, DF, additional, McShane, LM, additional, and Nielsen, TO, additional

Published
2016
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18. Abstract P3-07-64: Association between gene variants in SULT1A1 and UGT1A4 and disease outcomes in patients enrolled in SWOG S0226 and treated with anastrozole alone or in combination with fulvestrant for metastatic breast cancer

Author

Kadlubar, SA, primary, Barlow, WE, additional, Mehta, RS, additional, Daniels, JR, additional, Albain, KS, additional, Vandengerg, TA, additional, Dakhil, SR, additional, Tirumali, NR, additional, Lew, DL, additional, Gralow, JR, additional, Livingston, RB, additional, Hortobagiyi, GN, additional, Hayes, DF, additional, and Rae, JM, additional

Published
2016
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19. Abstract S3-02: Molecular predictors of outcome on adjuvant CAF plus tamoxifen (T) vs T in postmenopausal patients (pts) with ER+, node+ breast cancer – Transcriptome expression analysis of the phase III trial SWOG-8814

Author

Albain, KS, primary, Crager, MR, additional, Barlow, WE, additional, Baehner, FL, additional, Bergamaschi, A, additional, Rae, JM, additional, Ravdin, PM, additional, Tripathy, D, additional, Gralow, JR, additional, Livingston, RB, additional, Osborne, CK, additional, Ingle, JN, additional, Pritchard, KI, additional, Davidson, NE, additional, Carey, LA, additional, Cherbavaz, DB, additional, Sing, AP, additional, Shak, S, additional, Hortobagyi, GN, additional, and Hayes, DF, additional

Published
2016
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22. Abstract P3-05-01: Molecular analysis of cancer tissue, circulating tumor cells (CTC) and cell-free plasma tumor DNA (ptDNA) suggests variable mechanisms of resistance to endocrine therapy (ET) in estrogen receptor (ER) positive metastatic breast cancer (MBC)

Author

Paoletti, C, primary, Aung, K, additional, Cannell, EM, additional, Darga, EP, additional, Chu, D, additional, Kidwell, KM, additional, Thomas, DG, additional, Tokudome, N, additional, Brown, ME, additional, McNutt, LM, additional, Gersch, C, additional, Schott, AF, additional, Park, BH, additional, Robinson, DR, additional, Chinnaiyan, AM, additional, Rae, JM, additional, and Hayes, DF, additional

Published
2016
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24. Abstract P2-08-01: Prospective trial of endocrine therapy alone in patients with estrogen receptor positive, HER2-negative, node-negative breast cancer: Results of the TAILORx low risk registry

Author

Sparano, JA, primary, Gray, RJ, additional, Makower, DF, additional, Pritchard, KI, additional, Albain, KS, additional, Hayes, DF, additional, Geyer, CE, additional, Dees, EC, additional, Perez, EA, additional, Olson, JA, additional, Zujweski, J, additional, Keane, MM, additional, Gomez Moreno, HL, additional, Reddi, RP, additional, Goggins, TF, additional, Mayer, IA, additional, Brufsky, AM, additional, Toppmeyer, DL, additional, Kaklamani, VG, additional, Atkins, JN, additional, Berenberg, JL, additional, and Sledge, GW, additional

Published
2016
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25. Abstract P2-02-19: Somatic genetic profiling of circulating tumor cells (CTC) in metastatic breast cancer (MBC) patients

Author

Paoletti, C, primary, Cani, AK, additional, Aung, K, additional, Darga, EP, additional, Cannell, EM, additional, Hovelson, DH, additional, Yazdani, M, additional, Blevins, AR, additional, Tokudome, N, additional, Larios, JM, additional, Thomas, DG, additional, Brown, ME, additional, Gersch, C, additional, Schott, AF, additional, Robinson, DR, additional, Chinnaiyan, AM, additional, Bischoff, F, additional, Hayes, DF, additional, Rae, JM, additional, and Tomlins, SA, additional

Published
2016
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28. Abstract S5-07: SWOG S0500 – A randomized phase III trial to test the strategy of changing therapy versus maintaining therapy for metastatic breast cancer patients who have elevated circulating tumor cell (CTC) levels at first follow-up assessment

Author

Smerage, JB, primary, Barlow, WE, additional, Hayes, DF, additional, Winer, EP, additional, Leyland-Jones, B, additional, Srkalovic, G, additional, Tejwani, S, additional, Schott, AF, additional, O'Rourke, MA, additional, Lew, DL, additional, Gralow, JR, additional, Livingston, RB, additional, and Hortobagyi, GN, additional

Published
2013
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29. Abstract P1-04-01: Significance of circulating tumor cells in metastatic triple negative breast cancer: Results of an open label, randomized, phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 tigatuzumab (TBCRC 019)

Author

Paoletti, C, primary, Li, Y, additional, Muñiz, MC, additional, Kidwell, KM, additional, Aung, K, additional, Thomas, DG, additional, Brown, ME, additional, Abramson, V, additional, Irvin, WJ, additional, Lin, NU, additional, Liu, M, additional, Nanda, R, additional, Nangia, J, additional, Storniolo, AM, additional, Traina, TA, additional, Vaklavas, C, additional, Van Poznak, CH, additional, Wolff, AC, additional, Forero, A, additional, and Hayes, DF, additional

Published
2013
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30. Abstract PD6-4: Heterogeneity of expression of estrogen receptor by circulating tumor cells suggests diverse mechanisms of resistance to fulvestrant in metastatic breast cancer patients

Author

Paoletti, C, primary, Muñiz, MC, additional, Aung, K, additional, Larios, J, additional, Thomas, DG, additional, Tokudome, N, additional, Brown, ME, additional, Connelly, MC, additional, Chianese, DA, additional, Schott, AF, additional, Henry, NL, additional, Rae, JM, additional, and Hayes, DF, additional

Published
2013
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31. Abstract P1-08-11: Association of variants in candidate genes on lipid profiles in women with early breast cancer on adjuvant aromatase inhibitor therapy

Author

Santa-Maria, CA, primary, Dantzer, J, additional, Li, L, additional, Skaar, T, additional, Oesterreich, S, additional, Rae, JM, additional, Zeruesenay, D, additional, Nguyen, AT, additional, Henry, NL, additional, Storniolo, AM, additional, Hayes, DF, additional, Blumenthal, RS, additional, Ouyang, P, additional, Post, W, additional, Flockhart, DA, additional, and Stearns, V, additional

Published
2013
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33. S1-1: A Phase III Randomized Trial of Anastrozole Versus Anastrozole and Fulvestrant as First-Line Therapy for Postmenopausal Women with Metastatic Breast Cancer: SWOG S0226.

Author

Mehta, RS, primary, Barlow, WE, additional, Albain, KS, additional, Vandenberg, T, additional, Dakhil, SR, additional, Tirumali, NR, additional, Lew, DL, additional, Hayes, DF, additional, Gralow, JR, additional, Livingston, RB, additional, and Hortobagyi, GN, additional

Published
2011
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36. OT1-03-01: A Randomized Phase III Clinical Trial of Standard Adjuvant Endocrine Therapy +/− Chemotherapy in Patients (pts) with 1–3 Positive Nodes, Hormone Receptor (HR)-Positive and HER2−Negative Breast Cancer with Recurrence Score (RS) of 25 or Less: SWOG S1007.

Author

Gonzalez-Angulo, AM, primary, Barlow, WE, additional, Gralow, JR, additional, Meric-Bernstam, F, additional, Hayes, DF, additional, Moinpour, CM, additional, Ramsey, SD, additional, Schott, AF, additional, Sparks, DB, additional, Albain, KS, additional, and Hortobagyi, GN, additional

Published
2011
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43. Abstract P2-14-09: Prospective Evaluation of Change in 2-Point Discrimination of Index Finger as a Potential Early Predictive Marker for Carpal Tunnel Syndrome among Women Receiving Adjuvant Aromatase Inhibitor Therapy for Postmenospausal Breast Cancer in the Exemestane and Letrozole Pharmacogenomics (ELPh) Trial

Author

Bardia, A, primary, Rosson, G, additional, Giles, J, additional, Cornblath, D, additional, Flockhart, D, additional, Hayes, DF, additional, Jeter, S, additional, Hayden, J, additional, Lemler, S, additional, Nguyen, A, additional, Storniolo, AM, additional, Tarpinian, K, additional, Zhang, Z, additional, Henry, NL, additional, and Stearns, V., additional

Published
2010
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48. Phase II Evaluation Of Thalidomide In Patients With Metastatic Breast Cancer

Author

Baidas, SM, primary, Winer, EP, additional, Fleming, GF, additional, Harris, L, additional, Pluda, JM, additional, Crawford, JG, additional, Yamauchi, H, additional, Isaacs, C, additional, Hanfelt, J, additional, Tefft, M, additional, Flockhart, D, additional, Johnson, MD, additional, Hawkins, MJ, additional, Lippman, ME, additional, and Hayes, DF, additional

Published
2001
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