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Your search keyword '"Hazlerigg, D.G."' showing total 19 results
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19 results on '"Hazlerigg, D.G."'

4. Cry1 circadian phase in vitro: wrapped up with an E-Box

Author

Fustin, J.M., O'Neill, J.S., Hastings, M.H., Hazlerigg, D.G., and Dardente, H.

Subjects
Circadian rhythms -- Research, Circadian rhythms -- Physiological aspects, Gene expression -- Research, Gene expression -- Physiological aspects, Genetic transcription -- Research, Genetic transcription -- Physiological aspects, Biological sciences
Published
2009

5. Timing as a sexually selected trait: the right mate at the right moment

Author

Hau, Michaela, Dominoni, D.M., Casagrande, S., Buck, Loren, Wagner, Gabriela, Hazlerigg, D.G., Greives, Timothy J., Hut, Roelof A, Hau, Michaela, Dominoni, D.M., Casagrande, S., Buck, Loren, Wagner, Gabriela, Hazlerigg, D.G., Greives, Timothy J., and Hut, Roelof A

Abstract

Sexual selection favours the expression of traits in one sex that attract members of the opposite sex for mating. The nature of sexually selected traits such as vocalization, colour and ornamentation, their fitness benefits as well as their costs have received ample attention in field and laboratory studies. However, sexually selected traits may not always be expressed: coloration and ornaments often follow a seasonal pattern and behaviours may be displayed only at specific times of the day. Despite the widely recognized differences in the daily and seasonal timing of traits and their consequences for reproductive success, the actions of sexual selection on the temporal organization of traits has received only scant attention. Drawing on selected examples from bird and mammal studies, here we summarize the current evidence for the daily and seasonal timing of traits. We highlight that molecular advances in chronobiology have opened exciting new opportunities for identifying the genetic targets that sexual selection may act on to shape the timing of trait expression. Furthermore, known genetic links between daily and seasonal timing mechanisms lead to the hypothesis that selection on one timescale may simultaneously also affect the other. We emphasize that studies on the timing of sexual displays of both males and females from wild populations will be invaluable for understanding the nature of sexual selection and its potential to act on differences within and between the sexes in timing. Molecular approaches will be important for pinpointing genetic components of biological rhythms that are targeted by sexual selection, and to clarify whether these represent core or peripheral components of endogenous clocks. Finally, we call for a renewed integration of the fields of evolution, behavioural ecology and chronobiology to tackle the exciting question of how sexual selection contributes to the evolution of biological clocks.

Published
2017

6. Disrupted seasonal biology impacts health, food security, and ecosystems: a call for integrated research

Author

Stevenson, T.J., Visser, M.E., Arnold, W., Barrett, P., Biello, S., Dawson, A., Denlinger, D.L., Dominoni, Davide, Ebling, F.J., Elton, S., Evans, N., Ferguson, H.M., Foster, R.G., Hau, M., Haydon, D.T., Hazlerigg, D.G., Heideman, P., Hopcraft, J.G.C., Jonsson, N.N., Kronfeld-Schor, N., Kumar, V., Lincoln, G.A., MacLeod, R., Martin, S.A.M., Martinez-Bakker, M., Nelson, R.J., Reed, T., Robinso, J.E., Rock, D., Schwartz, W.J., Steffan-Dewenter, I., Tauber, E., Thackeray, S.J., Umstatter, C., Yoshimura, T., Helm, B., and Animal Ecology (AnE)

Subjects
international
Abstract

The rhythm of life on earth is shaped by seasonal changes in the environment. Plants and animals show profound annual cycles in physiology, health, morphology, behaviour and demography in response to environmental cues. Seasonal biology impacts ecosystems and agriculture, with consequences for humans and biodiversity. Human populations show robust annual rhythms in health and well-being, and the birth month can have lasting effects that persist throughout life. This review emphasizes the need for a better understanding of seasonal biology against the backdrop of its rapidly progressing disruption through climate change, human lifestyles and other anthropogenic impact. Climate change is modifying annual rhythms to which numerous organisms have adapted, with potential consequences for industries relating to health, ecosystems and food security. Disconcertingly, human lifestyles under artificial conditions of eternal summer provide the most extreme example for disconnect from natural seasons, making humans vulnerable to increased morbidity and mortality. In this review, we introduce scenarios of seasonal disruption, highlight key aspects of seasonal biology and summarize from biomedical, anthropological, veterinary, agricultural and environmental perspectives the recent evidence for seasonal desynchronization between environmental factors and internal rhythms. Because annual rhythms are pervasive across biological systems, they provide a common framework for trans-disciplinary research.

Published
2015

7. Deiodinases in the sheep hypothalamus: differential photoperiodic and endogenous spatiotemporal gene expression

Author

Saenz de Miera, Christina, Hanon, Elodie, Dardente, Hugues, Birnie, Michael, Simonneaux, Valérie, Lincoln, Gerald, Hazlerigg, D.G., University of Aberdeen, Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), University of Edinburgh, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), British Society for Neuroendocrinology (BSN). GBR., Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), and ProdInra, Migration

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2012

8. Neuroendocrine control of parr-smolt transformation in Atlantic salmon

Author

Casadei, Elisa, Ciborowski, Kate, Lorgen, Marlene, Dardente, Hugues, Hazlerigg, D.G., Martin, Sam, ProdInra, Migration, University of Aberdeen, Institut of Zoology, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), British Society for Neuroendocrinology (BSN). GBR., and Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2012

9. A transgenic test of the role of Cryptochrome1 in the seasonal neuroendocrine response in mammals

Author

Dardente, Hugues, Lillico, Simon G., Whitelaw, C.B., Lincoln, G.A., Hazlerigg, D.G., ProdInra, Migration, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), University of Aberdeen, BBSRC Roslin Institute, Partenaires INRAE, Queen's Medical Researche Institute, University of Edinburgh, British Society for Neuroendocrinology (BSN). GBR., and Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT], [SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2012

10. Circadian pacemaking within the suprachiasmatic nucleus analysed with a novel mCry1::luciferase transgenic mouse

Author

Hastings, M.H., Le Drynan, L.F., Chesham, J.C., Fustin, J.M., Dardente, Hugues, Hazlerigg, D.G., Maywood, E.S., University of Cambridge [UK] (CAM), Institute of Biological and Environmental Sciences, University of Aberdeen, Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], neuroscience, [SDV]Life Sciences [q-bio], suprachiasmatic nucleus, souris transgénique, [INFO]Computer Science [cs], [INFO] Computer Science [cs], BIOLOGIE MOLECULAIRE, luciférase, ComputingMilieux_MISCELLANEOUS, circadien, transcription factor
Abstract

International audience

Published
2011

11. Modulation of MT1 function in the PT: a role for RGS4 in photoperiodic signaling

Author

Dupré, S.M., Dardente, Hugues, Birnie, M.J., Loudon, A.S.I., Lincoln, G.A., Hazlerigg, D.G., Faculty of Life Sciences, University of Manchester [Manchester], Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), Institute of Biological and Environmental Sciences, University of Aberdeen, Queen's Medical Researche Institute, University of Edinburgh, Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), and ProdInra, Migration

Subjects
[SDV] Life Sciences [q-bio], tsh, [SDV]Life Sciences [q-bio], rgs4, [INFO]Computer Science [cs], [INFO] Computer Science [cs], récepteur mt1, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2011

12. Evidence for RGS4 modulation of melatonin and thyrotrophin signalling pathways in the pars tuberalis

Author

Dupré, S.M., Dardente, Hugues, Birnie, M.J., Loudon, A.S.I., Lincoln, G.A., Hazlerigg, D.G., Faculty of Life Sciences, University of Manchester [Manchester], Physiologie de la reproduction et des comportements [Nouzilly] (PRC), Centre National de la Recherche Scientifique (CNRS)-Université de Tours-Institut Français du Cheval et de l'Equitation [Saumur]-Institut National de la Recherche Agronomique (INRA), Institute of Biological and Environmental Sciences, University of Aberdeen, Queen's Medical Research Institute, University of Edinburgh, Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours-Centre National de la Recherche Scientifique (CNRS), Queen's Medical Researche Institute, and Institut National de la Recherche Agronomique (INRA)-Institut Français du Cheval et de l'Equitation [Saumur]-Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS)

Subjects
tsh, rgs4, melatonin, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], camp, pars tuberalis
Abstract

absent

Published
2011
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13. Disrupted seasonal biology impacts health, food security and ecosystems

Author

Stevenson, T.J., Visser, M.E., Arnold, W., Barrett, P., Biello, S., Dawson, A., Denlinger, D.L., Dominoni, D., Ebling, F.J., Elton, S., Evans, N., Ferguson, H.M., Foster, R.G., Hau, M., Haydon, D.T., Hazlerigg, D.G., Heideman, P., Hopcraft, J.G.C., Jonsson, N.N., Kronfeld-Schor, N., Kumar, V., Lincoln, G.A., MacLeod, R., Martin, S.A.M., Martinez-Bakker, M., Nelson, R.J., Reed, T., Robinson, J.E., Rock, D., Schwartz, W.J., Steffan-Dewenter, I., Tauber, E., Thackeray, S.J., Umstatter, C., Yoshimura, T., Helm, B., Stevenson, T.J., Visser, M.E., Arnold, W., Barrett, P., Biello, S., Dawson, A., Denlinger, D.L., Dominoni, D., Ebling, F.J., Elton, S., Evans, N., Ferguson, H.M., Foster, R.G., Hau, M., Haydon, D.T., Hazlerigg, D.G., Heideman, P., Hopcraft, J.G.C., Jonsson, N.N., Kronfeld-Schor, N., Kumar, V., Lincoln, G.A., MacLeod, R., Martin, S.A.M., Martinez-Bakker, M., Nelson, R.J., Reed, T., Robinson, J.E., Rock, D., Schwartz, W.J., Steffan-Dewenter, I., Tauber, E., Thackeray, S.J., Umstatter, C., Yoshimura, T., and Helm, B.

Abstract

The rhythm of life on earth is shaped by seasonal changes in the environment. Plants and animals show profound annual cycles in physiology, health, morphology, behaviour and demography in response to environmental cues. Seasonal biology impacts ecosystems and agriculture, with consequences for humans and biodiversity. Human populations show robust annual rhythms in health and well-being, and the birth month can have lasting effects that persist throughout life. This review emphasizes the need for a better understanding of seasonal biology against the backdrop of its rapidly progressing disruption through climate change, human lifestyles, and other anthropogenic impact. Climate change is modifying annual rhythms to which numerous organisms have adapted, with potential consequences for industries relating to health, ecosystems and food security. Disconcertingly, human lifestyles under artificial conditions of eternal summer provide the most extreme example for disconnect from natural seasons, making humans vulnerable to increased morbidity and mortality. In this paper, we introduce scenarios of seasonal disruption, highlight key aspects of seasonal biology, and summarize from biomedical, anthropological, veterinary, agricultural and environmental perspectives the recent evidence for seasonal desynchronization between environmental factors and internal rhythms. Because annual rhythms are pervasive across biological systems, they provide a common framework for trans-disciplinary research.

Published
2015

14. Association between mammalian lifespan and circadian free-running period: the circadian resonance hypothesis revisited

Author

Wyse, C.A., Coogan, Andrew, Selman, C., Hazlerigg, D.G., Speakman, J.R., Wyse, C.A., Coogan, Andrew, Selman, C., Hazlerigg, D.G., and Speakman, J.R.

Abstract

Biological rhythms that oscillate with periods close to 24 h (circadian cycles) are pervasive features of mammalian physiology, facilitating entrainment to the 24 h cycle generated by the rotation of the Earth. In the absence of environmental time cues, circadian rhythms default to their endogenous period called tau, or the free-running period. This sustained circadian rhythmicity in constant conditions has been reported across the animal kingdom, a ubiquity that could imply that innate rhythmicity confers an adaptive advantage. In this study, we found that the deviation of tau from 24 h was inversely related to the lifespan in laboratory mouse strains, and in other rodent and primate species. These findings support the hypothesis that misalignment of endogenous rhythms and 24 h environmental cycles may be associated with a physiological cost that has an effect on longevity.

Published
2010

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