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1. Abstracts from the 3rd International Severe Asthma Forum (ISAF)

Author

M. E. Ketelaar, K. Van De Kant, F. N. Dijk, E. M. M. Klaassen, N. Grotenboer, M. C. Nawijn, E. Dompeling, G. H. Koppelman, Clare Murray, Philip Foden, Lesley Lowe, Hannah Durrington, Adnan Custovic, Angela Simpson, Andrew J. Simpson, Dominick E. Shaw, Ana R. Sousa, Louise J. Fleming, Graham Roberts, Ioannis Pandis, Aruna T. Bansal, Julie Corfield, Scott Wagers, Ratko Djukanovic, Kian Fan Chung, Peter J. Sterk, Jorgen Vestbo, Stephen J. Fowler, S. J. Tebbutt, A. Singh, C. P. Shannon, Y. W. Kim, C. X. Yang, G. M. Gauvreau, J. M. Fitzgerald, L. P. Boulet, P. M. O’Byrne, N. Begley, A. Loudon, D. W. Ray, Selene Baos, Lucía Cremades, David Calzada, Carlos Lahoz, Blanca Cárdaba, Kewal Asosingh, Chris Lauruschkat, Kimberly Queisser, Nicholas Wanner, Kelly Weiss, Weiling Xu, Serpil Erzurum, Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Carolea Logun, Sara Alsaaty, Rosemarie Cuento, Rongman Cai, Junfeng Sun, Oswald Quehenberger, Aaron Armando, Edward Dennis, Stewart Levine, James Shelhamer, Kilyong Choi, Snezhina Lazova, Penka Perenovska, Dimitrinka Miteva, Stamatios Priftis, Guergana Petrova, Vassil Yablanski, Evgeni Vlaev, Hristina Rafailova, Takashi Kumae, L. J. Holmes, J. Yorke, D. M. Ryan, Sasawan Chinratanapisit, Khlongtip Matchimmadamrong, Jitladda Deerojanawong, Wissaroot Karoonboonyanan, Paskorn Sritipsukho, Vania Youroukova, Denitsa Dimitrova, Yanina Slavova, Spaska Lesichkova, Iren Tzocheva, Snezhana Parina, Svetla Angelova, Neli Korsun, Mihai Craiu, Iustina Violeta Stan, Matea Deliu, Tolga Yavuz, Matthew Sperrin, Umit M. Sahiner, Danielle Belgrave, Cansin Sackesen Sackesen, Ömer Kalayci, Petar Velikov, Tsvetelina Velikova, Ekaterina Ivanova-Todorova, Kalina Tumangelova-Yuzeir, Dobroslav Kyurkchiev, Spyridon Megremis, Bede Constantinides, Alexandros Georgios Sotiropoulos, Paraskevi Xepapadaki, David Robertson, Nikolaos Papadopoulos, Maxim Wilkinson, Craig Portsmouth, David Ray, Royston Goodacre, Anna Valerieva, Irina Bobolea, Daiana Guillén Vera, Gabriel Gonzalez-Salazar, Carlos Melero Moreno, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, R. Wang, I. Satia, R. Niven, J. A. Smith, T. Southworth, J. Plumb, V. Gupta, J. Pearson, I. Ramis, M. D. Lehner, M. Miralpeix, D. Singh, Imran Satia, Mark Woodhead, Paul O’Byrne, Jaclyn Ann Smith, Cecilia Forss, Peter Cook, Sheila Brown, Freya Svedberg, Katherine Stephenson, Margherita Bertuzzi, Elaine Bignell, Malin Enerbäck, Danen Cunoosamy, Andrew Macdonald, Caini Liu, Liang Zhu, Kiochi Fukuda, Cunjin Zhang, Suidong Ouyang, Xing Chen, Luke Qin, Suguna Rachakonda, Mark Aronica, Jun Qin, Xiaoxia Li, Marie-Chantal Larose, Anne-Sophie Archambault, Véronique Provost, Jamila Chakir, Michel Laviolette, Nicolas Flamand, Nicola Logan, Dominik Ruckerl, Judith E. Allen, Tara E. Sutherland, E. Hamelmann, C. Vogelberg, S. Goldstein, G. E. Azzi, M. Engel, R. Sigmund, S. J. Szefler, Raquel Mesquita, Luis Coentrão, Rui Veiga, José-Artur Paiva, Roberto Roncon-Albuquerque, Wendy Vargas Porras, Ana González Moreno, Jesus Macías Iglesias, Gustavo Córdova Ramos, Yesenia Peña Acevedo, Miguel Angel Tejedor Alonso, Maria Del Mar Moro Moro, Irena Krcmova, Jakub Novosad, Nicola Alexander Hanania, Marc Massanari, Heike Hecker, Eric Kassel, Craig Laforce, Kathy Rickard, Sanne Snelder, Gert-Jan Braunstahl, T. L. Jones, D. Neville, E. R. Heiden, E. Lanning, T. Brown, H. Rupani, K. S. Babu, A. J. Chauhan, M. Y. Eldegeir, A. A. Chapman, M. Ferwana, and M. Caldron

Subjects
Immunologic diseases. Allergy, RC581-607
Published
2017
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2. Neue Therapieansätze bei Nahrungsmittelallergie

Author

Heike Hecker

Subjects
Gynecology, medicine.medical_specialty, business.industry, medicine, Head and neck surgery, business
Abstract

Im Management der Nahrungsmittelallergie steht derzeit immer noch die Karenz des betreffenden Nahrungsmittels im Vordergrund. Bei Kreuzallergien kann eine spezifische Immuntherapie mit den entsprechenden Pollenallergenen in Erwagung gezogen werden. Studienergebnisse lassen darauf hoffen, dass auch fur die primare Nahrungsmittelallergie in absehbarer Zeit Praparate zur spezifischen Immuntherapie mit Nahrungsmittelallergenen zur Verfugung stehen konnten.

Published
2019
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3. Abstracts from the 3rd International Severe Asthma Forum (ISAF)

Author

Khlongtip Matchimmadamrong, J. Yorke, M. C. Nawijn, David Robertson, Serpil C. Erzurum, Evgeni Vlaev, Matthew Sperrin, Cecilia Forss, Jun Qin, A. A. Chapman, E. M. M. Klaassen, K. S. Babu, Tsvetelina Velikova, Consuelo Fernandez Rodriguez, Natividad De Las Cuevas Moreno, Rui Veiga, Nicola Logan, Clare S. Murray, Dominick E. Shaw, Vandana Gupta, Peter C. Cook, Li-Yuan Chen, Junfeng Sun, Louise Fleming, Sanne M. Snelder, Irina Bobolea, Dave Singh, N. Begley, James Shelhamer, Xing Chen, Kimberly Queisser, Gabriel Gonzalez-Salazar, Dan Neville, Freya Svedberg, Andrew Simpson, Jamila Chakir, C. P. Shannon, L. J. Holmes, Mark Woodhead, Philip Foden, Maria Del Mar Moro Moro, Yueqin Liu, Judith E. Allen, Gail M. Gauvreau, Paskorn Sritipsukho, Gustavo Córdova Ramos, Caini Liu, Miguel Angel Tejedor Alonso, Liang Zhu, Peter J. Sterk, Xiaoxia Li, David W. Ray, Stan Szefler, E. Dompeling, Blanca Cárdaba, Edward Dennis, Daiana Guillén Vera, Rosemarie Cuento, Oswald Quehenberger, Ana González Moreno, Kathy Rickard, Ellie Lanning, Kalina Tumangelova-Yuzeir, Eckard Hamelmann, Bede Constantinides, Tom C. Brown, M. Caldron, G. E. Azzi, Marie-Chantal Larose, Carlos Lahoz, Luis Coentrão, Andrew Macdonald, Penka Perenovska, Michael Engel, F. N. Dijk, Yesenia Peña Acevedo, S. J. Tebbutt, M. E. Ketelaar, I. Satia, Weiling Xu, Nicolas Flamand, Isabel Ramis, José-Artur Paiva, Maxim Wilkinson, Martin D. Lehner, J. M. Fitzgerald, Eric Kassel, Nicholas Wanner, Takashi Kumae, Y. W. Kim, N. Grotenboer, S. Goldstein, Montserrat Miralpeix, Kian Fan Chung, Omer Kalayci, Véronique Provost, Umit Murat Sahiner, Anne-Sophie Archambault, M. Ferwana, Milena Sokolowska, M. Y. Eldegeir, Svetla Angelova, Sasawan Chinratanapisit, David Calzada, Kilyong Choi, Nikolaos G. Papadopoulos, Matea Deliu, Spaska Lesichkova, Roberto Roncon-Albuquerque, Ana R. Sousa, Scott Wagers, Tolga S Yavuz, Vassil Yablanski, Margherita Bertuzzi, D. M. Ryan, Carlos Melero Moreno, Carolea Logun, Christian Vogelberg, Elaine Bignell, Petar Velikov, Ratko Djukanovic, Ralf Sigmund, Anna Valerieva, Spyridon Megremis, Snezhina Lazova, R. Niven, A. Singh, Danen Cunoosamy, Paraskevi Xepapadaki, Craig Laforce, Wendy Vargas Porras, Aruna T. Bansal, Adnan Custovic, Michel Laviolette, Chris Lauruschkat, Jakub Novosad, Katherine Stephenson, Jesus Macías Iglesias, Paul M. O'Byrne, R. Wang, Yanina Slavova, K.D.G. van de Kant, Cunjin Zhang, Ekaterina Ivanova-Todorova, Wissaroot Karoonboonyanan, Iren Tzocheva, Tara E. Sutherland, Jørgen Vestbo, Selene Baos, Mihai Craiu, Andrew S. I. Loudon, Guergana Petrova, Aaron Armando, Danielle Belgrave, Dimitrinka Miteva, Suguna Rachakonda, Lucía Cremades, Craig Portsmouth, Royston Goodacre, Marc Massanari, Sheila Brown, C. X. Yang, Irena Krčmová, Louis P. Boulet, Suidong Ouyang, Snezhana Parina, Thomas Southworth, Vania Youroukova, Sara Alsaaty, Anoop Chauhan, P. M. O’Byrne, Emily Heiden, Mark A. Aronica, Hristina Rafailova, J. Pearson, Kelly Weiss, J. A. Smith, Imran Satia, Angela Simpson, Dominik Rückerl, Dobroslav Kyurkchiev, Jitladda Deerojanawong, Asuncion Martinez-Anton, Kiochi Fukuda, Graham Roberts, Neli Korsun, Jaclyn A. Smith, Kewal Asosingh, Lesley Lowe, Gerard H. Koppelman, Nicola A. Hanania, Stewart Levine, Raquel Mesquita, Denitsa Dimitrova, Stamatios Priftis, Heike Hecker, Hannah J. Durrington, Ioannis Pandis, Julie Corfield, Hitasha Rupani, D. W. Ray, Iustina Violeta Stan, Thomas Jones, Gert-Jan Braunstahl, Alexandros Georgios Sotiropoulos, Rongman Cai, Luke Qin, Stephen J. Fowler, Malin Enerbäck, Jonathan Plumb, Cansin Sackesen, and Çocuk Sağlığı ve Hastalıkları

Subjects
Pulmonary and Respiratory Medicine, medicine.medical_specialty, Allergy, business.industry, Severe asthma, Immunology, RC581-607, medicine.disease, Meeting Abstracts, medicine, Immunology and Allergy, Immunologic diseases. Allergy, Intensive care medicine, business
Published
2017
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4. Accelerated up-dosing of subcutaneous immunotherapy with a registered allergoid grass pollen preparation

Author

Oliver Pfaar, Esther van Twuijver, Heike Hecker, Johan Diderik Boot, Ronald van Ree, Ludger Klimek, AII - Amsterdam institute for Infection and Immunity, APH - Amsterdam Public Health, and Experimental Immunology

Subjects
Adult, Male, Allergy, Rhinitis, Allergic, Perennial, Adolescent, Injections, Subcutaneous, Immunology, medicine.disease_cause, Drug Administration Schedule, Young Adult, Pollen, Grass pollen, Allergoids, Subcutaneous immunotherapy, medicine, otorhinolaryngologic diseases, Humans, Immunology and Allergy, Dosing, Aged, Conjunctivitis, Allergic, Plant Extracts, business.industry, Maintenance dose, Rhinitis, Allergic, Seasonal, General Medicine, Allergens, Antigens, Plant, Middle Aged, medicine.disease, Rhinitis, Allergic, Asthma, Regimen, Allergoid, Desensitization, Immunologic, Immunoglobulin G, Female, business
Abstract

Background: Climatic changes causing early pollen flight and new allergens prolonging the pollen season render up-dosing of allergen-specific subcutaneous immunotherapy (SCIT) outside the pollen season considerably more difficult. In addition, for patients with multiple pollen allergies, patients coming near the beginning of pollen season, and patients who wish to up-dose faster, an accelerated induction regimen would be helpful. Methods: In an open, randomized, parallel group, multicenter safety trial, an accelerated up-dosing regimen (0.1–0.3–0.5 ml in weekly intervals) was compared to conventional up-dosing (0.05–0.1–0.2–0.3–0.4–0.5 ml in weekly intervals) with an allergoid grass pollen SCIT preparation. After up-dosing, the maintenance dose was given in monthly intervals. Results: A total of 146 adult patients with rhinitis or rhinoconjunctivitis with or without mild asthma (FEV1 >70%) due to grass pollen were randomized to either the conventional registered up-dosing or an accelerated regimen. In both groups (accelerated regimen, n = 69; conventional regimen, n = 75), a high proportion of patients (92.75 and 92.0%, respectively) successfully reached the maintenance dose without safety concerns. Furthermore, significant increases in specific IgG and IgG4 after 4 months of treatment were observed in both groups. Conclusion: The accelerated SCIT regimen was found to be as safe as the conventional regimen and might be used to up-dose patients within 2 weeks. Moreover, the immunological effects of both up-dosing regimens were comparable.

Published
2013
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5. Contents Vol. 160, 2013

Author

Christine M. Venema, Oliver Pfaar, Chisato Mori, J. Kressel, TM deRossi, Yoichi Kohno, Alexander F. Hagel, L. García-Marcos, Barbara Frossi, Esther van Twuijver, Mark Larché, Chun-Ming Chen, Xavier Basagaña, Torsten Zuberbier, D. Hervás, M. Jose Torres, Yuzaburo Inoue, Josep M. Antó, Philippe-Jean Bousquet, P C Konturek, Naoki Uehara, Naoki Shimojo, N. Matamoros, Jean Bousquet, Linda Cox, Jan-Paul Zock, Ludger Klimek, J. Milá, David H. Broide, Inmaculada Andreu, Li-Chen Chen, Sergio Bonini, Satz Mengensatzproduktion, Cheng-Jang Wu, Anne-Elie Carsin, Laurel J. Gershwin, Antje H. Fink-Wagner, Shingo Ochiai, Osman M. Yusuf, Johan Diderik Boot, Inmaculada Doña, Mayuko Nakaya, Lars Jacobsen, Hans Oman, Patrizia Pignatti, Carol R. Reinero, Druck Reinhardt Druck Basel, L. Karla Arruda, Barbara Bohle, Pascal Demoly, Takayasu Arima, Ana Aranda, Giovanni Passalacqua, Deborah Jarvis, Chin-Yu Yang, Heike Hecker, Kurt J. Williams, Jordi Sunyer, Anna Pomés, Adriana Ariza, E.G. Hahn, Ruby Pawankar, Minako Tomiita, Wolfgang Dauth, Stephan A. Carey, Bjoern Peters, Carlo Pucillo, Philippe Devillier, Martin Raithel, Luca Perfetti, Yi-Hsin Chen, Natalia Blanca-López, J.A. Hervás, M. Isabel Montañez, Yoshinori Morita, Sandra González Díaz, Carlos E. Baena-Cagnani, Christer Janson, Cristobalina Mayorga, Stefan Vieths, G. Walter Canonica, Enrique Fernández-Caldas, Kamal Mesbah, Sara Negri, Ming-Ling Kuo, Yurdagül Zopf, Ronald van Ree, Kerrie Vaughan, Joachim Heinrich, Gianni Pala, Marcello Imbriani, Yasunori Sato, Enrico Compalati, Edurne Nuin, Miguel A. Miranda, J. Pons, Kjell Toren, Alessandro Sette, Gianna Moscato, Yoichi Suzuki, and Miguel Blanca

Subjects
business.industry, Immunology, Immunology and Allergy, Medicine, General Medicine, business
Published
2013
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