49 results on '"Hellawell, Jennifer"'
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2. Evaluation of the Pharmacokinetics and Safety of AMG 986 Tablet and Capsule Formulations in Healthy Adult Subjects: A Phase I, Open-Label, Randomized Study
3. A Phase I, Open-label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of AMG 986 in Healthy Japanese Subjects
4. Pharmacokinetics, Pharmacodynamics, and Tolerability of Olpasiran in Healthy Japanese and Non-Japanese Participants: Results from a Phase I, Single-dose, Open-label Study
5. Effect of Severe Renal Impairment on the Safety, Tolerability, and Pharmacokinetics of AMG 986
6. Preclinical development and phase 1 trial of a novel siRNA targeting lipoprotein(a)
7. Zodasiran, an RNAi Therapeutic Targeting ANGPTL3, for Mixed Hyperlipidemia
8. Plozasiran, an RNA Interference Agent Targeting APOC3, for Mixed Hyperlipidemia
9. A Phase I, Multiple-Dose, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Pharmacokinetics, Safety, and Tolerability of Etelcalcetide Administered Intravenously to Chinese Patients With Chronic Kidney Disease Undergoing Hemodialysis
10. Reassessing Phase II Heart Failure Clinical Trials
11. Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia: The SHASTA-2 Randomized Clinical Trial.
12. Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis
13. Zodasiran silences hepatic ANGPTL3 leading to deep and durable reductions in atherogenic lipids and lipoproteins in mixed dyslipidemia patients: Final results from arches-2, double-blind period
14. Plozasiran (ARO-APOC3), decreases APOC3 and triglycerides (TG) in patients with mixed dyslipidemia: MUIR final results
15. Abstract 13951: Safety, Tolerability and Efficacy of Single-dose Amg 890, a Novel Sirna Targeting Lp(a), in Healthy Subjects and Subjects With Elevated Lp(a)
16. Occurrence of Clinically Diagnosed Hypertrophic Cardiomyopathy in the United States
17. †Plozasiran (ARO-APOC3), an Investigational RNAi, Demonstrates Robust and Durable TG Reductions in Patients with Mixed Dyslipidemia, MUIR Final Results
18. Abstract 15437: A Phase 3 Single-Blind Study of Eleclazine in Subjects With Type 3 Long QT Syndrome
19. A First-in-Human Study of AMG 986, a Novel Apelin Receptor Agonist, in Healthy Subjects and Heart Failure Patients
20. A Phase 1, Open‐Label Study to Evaluate the Effect of Food and Concomitant Itraconazole Administration on the Pharmacokinetics of AMG 986 in Healthy Subjects
21. Contributors
22. 76 - Familial Cardiomyopathies
23. Myocardial Reverse Remodeling
24. Temporal Associations Between Thoracic Volume Overload and Malignant Ventricular Arrhythmias: A Study of Intrathoracic Impedance
25. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Of Amg 986, a Novel Small Molecule Apelin Receptor Agonist, in Healthy Subjects and Heart Failure Patients
26. Magnetic Resonance Imaging Captures the Biology of Ductal Carcinoma In Situ
27. Contributors
28. First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers
29. First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers
30. AG10, A Novel, Potent and Selective Transthyretin Stabilizer, is Well Tolerated at Doses Resulting in Target Therapeutic Blood Levels, and Demonstrates Clinical Proof-of-Concept in Healthy Volunteers
31. Reassessing Phase II Heart Failure Clinical Trials: Consensus Recommendations.
32. Novel Approach Targeting the Complex Pathophysiology of Hypertrophic Cardiomyopathy
33. Pharmacokinetic evaluation of treprostinil (oral) for the treatment of pulmonary arterial hypertension
34. Myocardial Reverse Remodeling
35. Temporal Associations Between Thoracic Volume Overload and Malignant Ventricular Arrhythmias: A Study of Intrathoracic Impedance
36. Synthesis, Activity, and Pharmacophore Development for Isatin-β-thiosemicarbazones with Selective Activity toward Multidrug-Resistant Cells
37. Pharmacokinetic evaluation of treprostinil(oral) for the treatment of pulmonary arterial hypertension
38. Anticancer Drugs as Carcinogens
39. Liver Cancer, Adult (Primary)
40. Prostate Cancer
41. Bile Duct Cancer
42. Cervical Cancer
43. Liver Cancer, Childhood (Primary)
44. Stem Cells
45. Carcinoma of Unknown Primary
46. Breast Diseases
47. Abstract 15377: Stabilization of Cardiac Function in Wild-Type Transthyretin Cardiac Amyloidosis With Diflunisal.
48. Plozasiran for Managing Persistent Chylomicronemia and Pancreatitis Risk.
49. Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells.
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