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4. Air pollution and incident sarcoidosis in central Pennsylvania.

Author

Yanosky, Jeff D., Washington, Abigail, Foulke, Galen T., Guck, Daniel, Butt, Melissa, and Helm, Matthew F.

Subjects
AIR pollution, SARCOIDOSIS, CHRONIC granulomatous disease, NOSOLOGY, LOGISTIC regression analysis, ETIOLOGY of diseases
Abstract

Sarcoidosis is a chronic granulomatous disease predominantly affecting the lungs and inducing significant morbidity and elevated mortality rate. The etiology of the disease is unknown but may involve exposure to an antigenic agent and subsequent inflammatory response resulting in granuloma formation. Various environmental and occupational risk factors have been suggested by previous observations, such as moldy environments, insecticides, and bird breeding. Our study investigated the association of air pollution with diagnosis of sarcoidosis using a case-control design. Penn State Health electronic medical records from 2005 to 2018 were examined for adult patients with (cases) and without (controls) an International Classification of Disease (ICD)-9 or −10 code for sarcoidosis. Patient addresses were geocoded and 24-hr residential-level air pollution concentrations were estimated using spatio-temporal models of particulate matter <2.5 μm (PM2.5), ozone, and PM2.5 elemental carbon (EC) and moving averages calculated. In total, 877 cases and 34,510 controls were identified. Logistic regression analysis did not identify significant associations between sarcoidosis incidence and air pollution exposure estimates. However, the odds ratio (OR) for EC for exposures occurring 7–10 years prior did approach statistical significance, and ORs exhibited an increasing trend for longer averaging periods. Data suggested a latency period of more than 6 years for PM2.5 and EC for reasons that are unclear. Overall, results for PM2.5 and EC suggest that long-term exposure to traffic-related air pollution may contribute to the development of sarcoidosis and emphasize the need for additional research and, if the present findings are substantiated, for public health interventions addressing air quality as well as increasing disease surveillance in areas with a large burden of PM2.5 and EC. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Atopic Dermatitis

Author

Clebak, Karl T., Helm, Leesha, Uppal, Prabhdeep, Davis, Christopher R., and Helm, Matthew F.

Abstract

Atopic dermatitis (AD) is a common, chronic relapsing, and remitting inflammatory skin disease that is characterized by erythematous, scaly, and pruritic lesions often located over the flexural surfaces. Treatment goals of AD include the reduction of itching and burning, as well as the reduction of skin changes. Treatment of AD includes emollients and skin care, topical therapies including topical corticosteroids and steroid-sparing therapies, systemic therapies, and phototherapy.

Published
2024
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9. The many variants of psoriasis

Author

Clebak, Karl T., Helm, Leesha, Helm, Matthew F., and Selverling, Elizabeth V.

Subjects
Skin, Psoriasis, Pimecrolimus, Health
Abstract

Erythema, skin thickening, and scales typify most cases, but other patterns exist. Tx choices may differ, depending on how much body surface area is covered. The 'heartbreak of psoriasis,' coined [...]

Published
2020

13. Atopic Dermatitis

Author

Clebak, Karl T., primary, Helm, Leesha, additional, Uppal, Prabhdeep, additional, Davis, Christopher R., additional, and Helm, Matthew F., additional

Published
2023
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14. Chronic blistering rash on hands: The location of the patient's lesions and multiple risk factors suggested that an uncommon disorder was at work

Author

Bazewicz, Christopher G., Helm, Matthew F., and Miller, Jeffrey J.

Subjects
Rash -- Risk factors, Medical examination, Drinking (Alcoholic beverages), Health
Abstract

A 60-YEAR-OLD MAN presented to our dermatology clinic with a chronic, recurrent pruritic rash on his hands and neck. He noted that the rash developed into blisters, which he would [...]

Published
2019

15. Cancer Screening for Dermatomyositis: A Survey of Indirect Costs, Burden, and Patient Willingness to Pay.

Author

Jicha, Katherine I., Bazewicz, Christopher G., Helm, Matthew F., Butt, Melissa, Shumaker, Kassidy, and Foulke, Galen T.

Subjects
DERMATOMYOSITIS, EARLY detection of cancer, WILLINGNESS to pay, CANCER education, PATIENTS' attitudes, BLOOD cell count
Abstract

The article focuses on cancer screening for dermatomyositis (DM) and includes topics such as the increased risk of malignancy in DM patients, the current screening modalities, and the indirect costs associated with these screenings. It study examines patient perspectives on burden and willingness to pay for cancer screenings, comparing the conventional cancer screening panel (CSP) and whole-body positron emission tomography/computed tomography (PET/CT).

Published
2023
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21. Contributors

Author

Abel, Dori, Abelman, Rebecca A., Abu Kar, Sarah, Abughazaleh, Saeed, Abu-Nejim, Husam, Afari, Maxwell Eyram, Ahmed, Hammood, Akoto, Shanice, Alabre, Kenneth, Ali, Fahad, Ali, Tanya, Alipanah-Lechner, Narges, Altunel, Erdem, Alzoebie, Lama, Anderson, Chelsie, Andrews, Christine B., Anthony, AnnGene, Arcand, Paul-Hugo, Arora, Sohrab, Asaro, Joseph A., Astashchanka, Anna, Atchison, Douglas, Aulakh, Sudeep K., Aurora, Taruna, Avasare, Rupali, Babadi, Baktash, Babar, Tania B., Bachman, Emelia Argyropoulos, Bains, Ashika, Balabanov, Roumen, Balaguera, Pedro, Balda, Javier, Bank, T. Caroline, Banwell, Brenda, Barrera, Francisco J., Barta, Samantha, Basman, Craig L., Bass, Crystal T., Beach, Scott R., Bediako, Persey, Belcher, Ren, Bell, Jennifer, Bellinghausen, Amy L., Bennett, Colleen E., Berkowitz, Carol D., Betageri, Omkar, Bharmal, Murtaza, Bhatt, Harikrashna B., Bhuptani, Prachi H., Bido-Medina, Richard O., Bielak, Kendall, Bilodeau, Courtney Clark, Bird, Lisa, Bishop, Erin, Bitar, Ghamar, Blakeney, Craig, Blatz, Allison M., Block, Brian, Bortz, Christina M., Bosse, Kristopher R., Bouton, Tara C., Bove, Mary E., Bowlby, Lynn A., Boyden, Sean, Brady, Mark F., Braide, Biobele, Brar, Jessica K., Bratman, Russell E., Brodowsky, Emily Chan, Brown, Austin K., Brown, Emily C.B., Brugnoni, Jessalyn, Bui, Eric, Burke, Christine, Burton, Lauren, Butler, Blythe, Butler, William, Byanova, Katerina L., Byg, Blaire, Callanan, Tucker C., Cantos, Adriana, Canty, Katherine W., Carragee, Eugene, Carrel-Lammert, Meredith, Castillo, Jorge J., Chait, Daniel, Chan, Philip A., Chapman, Arlene, Chatterjee-Paer, Sudeshna, Cheng, Vicky, Chien, Michael, Chilcote, Jeffrey, II, Childs, Candicee, Chopra, Amit, Chou, Stella T., Choudhury, Natasha, Christian, Cindy W., Chua, Winona, Chun, Andrew S., Claman, David, Clark, Grace V., Clark, Seth, Clarke, Ross, Clay, Alexandra, Clebak, Karl T., Cleland, Derrick, Cohen, Debbie L., Cohen, Lisa, Congdon, Morgan, Constantinou, Maria, Cooper, James Elliott, Corley, James Earl, Cosgrove, Abigail, Covarrubias, Oscar, Craine, Rebecca, Criddle, Sarah, Cristofaro, Patricia, Cunha, Joanne Szczygiel, Cunningham, Karlene, Cusano, Joseph, D’Alessandro, Frank B., Dado, Lynn, Daneshdoost, Shanaz, Daneshvari, Nicholas Omid, Darwiche, Sabrina, Das, Abhijit, DaSilva, Manuel F., De La Garza, Carlos, DeDent, Alison, Deeb, Mery, Denninger, John W., Desrochers, Colette, Devon, Erin Pete, Diaz, Joseph A., DiGrande, Kyle, Dina, Ayodeji, Doo, Kathleen, Drury, Brian, Dus, Bethany, Dutta, Roop, Dworkin, Myles, Dyster, Timothy G., Ebert, Eric, Edmund, Joseph, Edward, Heather L., Eggers, Erica, Eisenhower, Christine, Ellsworth, Pamela, Elnair, Radowan, Escamilla-Ocañas, César E., Espinosa, Patricio Sebastian, Faber, Mark D., Facer, Evan, Fadale, Paul D., Fallon, Ryan T., Farias, Michael J., Farkas, Jon, Farrand, Erica, Farrell, Ronan, Fay, Kevin S., Fender, Robert Zachary, Hernandez, Samantha Fernandez, Fernandez-Robles, Carlos, Ferreira, Jason D., Ferri, Fred F., Ferri, Heather, Fields, Jessica C., Fields, Lauren, Fischer, Staci A., Fiske, Hannah, Florez, Maria Camila Velez, Forbes, Kellie C., Forcier, Michelle, Ford, Sydney, Fort, Frank G., Fort, Glenn G., Frankel, Eitan S., Freeman, Nancy, Friedman, Ryan, Frisch, Daniel R., Fru, Relindis Azenwi, Fullenkamp, Lynn C., Gaffney, Michael, Garcia, Jose P., Garcia, Paloma Jolin, Ge, Jonathan S., Gesthalter, Yaron B., Ghimire, Anil, Gibson, Christopher, Gidwani, Nisha H., Gilek-Seibert, Katarzyna, Gilvaz, Vinit J., Glueck, Jacob, Goetz, Jennifer Leah, Goldburt, Alla, Goldsmith, Corey Elam, Rao Golla, Maheswara Satya Gangadhara, Gomez, Alexander, Slagle, Helen B. Gomez, Greenblatt, H. Karl, Greenfield, Morgan, Gugerty, Lindsay, Gultawatvichai, Patan, Gunning, Samantha, Guo, David, Gupta, Simran, Guttadauria, Brittany, Gwinn, Meghan, Hadi, Mohanad, Hafeez, Muhammad Ubaid, Hall, Hayden, Hall, Sarah, Handa, Sajeev, Hanna, John R., Harbord, Nikolas, Hardacker, Kyle, Hardesty, Anna, Haribhakti, Nirav, Harris, Daniel J., Hartmann, Abigail, Hartnett, Davis A., Hartvigsen, Nathan, Hawkins, Brian, He, Elaine, Heinle, Rachel Wright, Helm, Leesha A., Helm, Matthew F., Herlevich, Thomas, Hermez, Klodia M., Hilliard, Ross W., Hocker, Nathaniel, Hoffman, R. Scott, Holton, Siri M., Homer, Alexander S., Hook, Benjamin E., Hsu, Raymond, Huang, Laurence, Hull, Mariam, Hume, Anne L., Hussain, Zilla, Huynh, Donny V., Hyder, Sarah, Ingraham, Caitlin, Insalaco, Louis F., Jackson, James, Jafari-Esfahani, Shadi, Jain, Rishubh, Jain, Vanita B.D., Jain, Vipul V., Jamal, Fariha, Janigian, Robert H., Jr., Jasuja, Sonia, Javier, Noelle Marie, Jayachandran, Nishant, Jetty, Vybhav, Johnson, Michael P., Johnson, Steven D., Jones, Amanda, Joseph, Tatiana, Joseph-Senatus, Ganaelle, Joshi, Shyam, Justice, Joshua, Kabashneh, Sohaip, Kadiyala, Vishnu, Kalligeros, Markos, Karthikeyan, Vanji, Kaske, Erika, Kasper, Vania, Kass, Joseph S., Kass, Naomi R., Kasthuri, Viknesh S., Katz, Luca, Kazakova, Vera, Keim, Jennifer L., Kensey, Nicholas, Kent, Victoria, Kerrigan, Danielle, Keselman, Dennis, Khare, Sarthak, Khatri, Surya, Khawaja, Hussain R., Khurana, Saranya S., Kifle, Betelhem, Kim, Chan Woo, Kim, Jinseong, Kisare, Samantha, Kohrman, Samuel I., Kokkirala, Aravind Rao, Konstantino, Yuval, Kontos, Nicholas, Kopyt, Nelson, Kothadia, Savan, Koti, Ajay S., Koulouridis, Ioannis, Kreider, Timothy R., Kron, Kevin, Krumm, Ilana, Kuhn, Elizabeth, Kumbar, Lalathaksha, Kuo, Sheng-Han, Kuris, Eren O., Kurss, David I., Kutschke, Michael J., Laband, William F., LaCombe, Philip, Lam, Uyen T., Lam, Wilson, Laredo, Jonathan, Larijani, Mary, Le, Peter, Leahy, Caroline, Leard, Lorriana E., Leavitt, David A., Leba, Christopher T., Lee, Hyung Jin, Lee, Kachiu C., LeGros, Tracy Leigh, Lemme, Nicholas J., L’Etoile, Nathan, Li, Jian, Lim, Carol, Lin, Chi-Ying (Roy), Lippincott, Jordan, Liu, Jonathan, Logue, Teresa C., Longtain, Riley, López, Gabriela, Lord, Kito Akin, Loscalzo, Kirsten, Lucas, Mathew J., Lucier, David J., Jr., Ma’ayeh, Marwan, MacLean, Rachel L., MacMurdo, Maeve G., Madva, Elizabeth N., Maher, Lewena, Makai, Gretchen, Malpica, Luis, Marks, Jonathan, Pinheiro, Ana Paula Marques, Marr, Mollie C., Martinez, Adali, Matin, Adiba, Mazzaglia, Peter J., Mbuyi, Nadine N., McCulloh, Russell J., McDonald-McGinn, Donna M., McGowen, Alexandra, McGraw, Katherine Elizabeth, McKenna, Jaclyn, McNamara, Kelly, Meleveedu, Kapil S., Mendez-Miller, Megan, Mercado, Jorge, Mercado, Osvaldo, Merritt, Rory, Michaels, Marian G., Michel, Jeremy, Mikolasko, Brian D., Milner, John D., Min, May, Minami, Taro, Mohamed, Mouhand F., Najjar-Mojarrab, Javad, Molinari, John, Montgrain, Philippe, Moon, Heesung, Moore, Michael Z., Moore, Shawn D., Morelli, Leah, Morrissey, Patrick J., Mughal, Aleem I., Mukkamalla, Shiva Kumar R., Mullen, Marguerite A., Mulliken, Alexandra, Mumtaz, Tayebah, Muraina, Fadeke, Mustafa, Ahmad, Myers, Ellen, Mylhousen, Emily, Nadaud, Jack, Nadella, Akash, Nadella, Mohnish, Nadjarian, Albert, Nagpal, Nikita, Nathan, Miriam, Naveed, Asim, Nawaiseh, Ahmad Al, Neff, Robert, Neithardt, Adrienne B., Nestlerode, Christina, Niazi, Azfar K., Nisavic, Mladen, Nokoff, Natalie, Noorbhai, Ibrahim Z.D., Novak, James E., Novarra, Austin, John, Audrey R. Odom, Okewunmi, Jeffrey, Oliver, Rebecca, Olszewski, Adam J., Onyeaka, Henry K., Orchowski, Lindsay M., Osorio, Marcela, Osorio, Luis, O’Sullivan, Cassidy, Outlaw, Jasmine, Oyelakin, Ayotomide, Pace, Paolo G., Paddock, John E., Painter, David F., Palmieri, Alicia, Pappas-Taffer, Lisa, Paranandi, Sneha, Parikh, Mihir, Partin, Michael T., Patel, Birju B., Patel, Melissa D., Patel, Minta, Patel, Nima R., Patel, Pranav M., Patel, Vishal I., Patrick, Brett, Paudel, Shreedhar, Pelcovits, Ari, Perez, David L., Perez, Jose J. Hermina, Pétron, Clément, Pfeuti, Courtney, Pham, Lily C., Phillips, Katharine A., Phillips, Oliver W., Phillips, Tara M., Piana, Lauren E., Portnoff, Brandon S., Pou, Sovijja, Prashar, Rohini, Pulice, Christine, Punko, Diana, Purkayastha, Ayan, Qawi, Imrana, Qu, David, Quesada, Adrian, Quinn, Matthew S., Racchi, Nicholas, Rachu, Gregory S., Rajadurai, Suvithan, Ramachandran, Lintu, Rana, Tanvi, Rathore, Bharti, Rathore, Ritesh, Raukar, Neha P., Ravindra, Lakshmi, Reagan, John L., Reardon, P.K., Reddy, Bharathi V., Reddy, Snigdha T., Reed-Weston, Anne, Reginato, Anthony M., Reichart, James P., Reus, Victor I., Reuter, Matthew, Riaz, Sana, Ricci, Brittany, Rich, Harlan G., Richter, Savanah, Rivera, Lauren Davis, Robertson, Melena J., Roby, Lauren C., Roche, Meaghan, Rodriguez, Alejandra E. Morfin, Gómez, Perla M. Romero, Ron, Hayley A., Rossi, Michael, Rubin, David, Rubin, Lila, Rushworth, Parker, Rutstein, Beth H., Sadeghi, Noushine, Sahota, Ruchi Jalota, Saks, Emily, Sall, Jeffrey W., Salvi, Joshua D., Sanchez, Frank A., Sanchez, Martha C., Sanka, Pranavi, Santhosh, Lekshmi, Santos, Linda Herrera, Sauck, Emily, Saylor, Leah, Scheuing, William J., Sciscione, Anthony, Scott, Matthew Thomas, Sederdahl, Bethany K., Seeber, Richard E., II, Sellers, Kyle, Sen, Aritra, Sewell, Rachel, Shaban, Hesham, Shah, Ankur, Shah, Isha, Shakil, Omair, Sharma, Animesh, Sharma, Yuvraj, Sharp, Lydia, Sherman, Alexander, Shill, Jessica E., Shimanovsky, Alexei, Shipp, Michael M., Shlossman, Philip A., Siddiqui, Khawja A., Siegel, Alyssa, Sigman, Mark, Singh, Harinder P., Singh, Jasneet, Singh, Manjot, Slingsby, Brett, Sloane, Amy J., Smick, Alexandra H., Smith, Jeanette G., Smith, Matthew J., Sohaney, Ryann, Soi, Vivek, Soinski, Rebecca, Soler, Maria E., Soman, Sandeep, Sorg, Emily, Sosnoski, Olivia, Sperati, C. John, Stanford, Nathan, Steele, Emery, Steele, Jacqueline, Stern, Ella, Stier, James, Stockwell, Philip, Subramanian, Lakshmi, Suen, Angela, Suh, Edward, Sundaramoorthy, Anjali, Sunkara, Naveena, Supanakorn, Varut, Suri, Priyasha, Sweeney, Hannah, Takasaki, Kaoru, Takei, Ryosuke, Tan, Laren, Tarawneh, Mohammad, Taylor, Alan, Taylor, Kathryn Marie, Taylor, Matthew A., Taylor, S. Trevor, Tenney-Soeiro, Rebecca, Thomas, Anthony G., Thompson, Stefani, Tien, Alexandra Meyer, Tien, David Robbins, Tierney, Anna-Marie, Toma, Helen, Lopez, Kim Tran, Tryforos, Margaret, Tsaban, Gal, Tschoe, Christine, Tungate, Robert, Turn, Christina S., Uduman, Junior, Umanath, Kausik, Ungar, Stephanie P., Vakili, Babak, van Deventer, Ella, Vemula, Ridhima, Venado, Aida, Vollum, Kathryn G., Vorel, Ethan, Walson, Ifeanyi, Wang, Angela, Wang, Emily, Wang, Li, Wehner, Linsey, Westreich, Roi, Wheeler, Ericka, Wighton, Nakia, Wildman, Alexis, Wilson, Annise, Winikor, Jared M., Wininger, Bryce, Winschel, Julia M., Wold, Jaclyn, Wolpaw, Adam J., Wolpert, Marlene Fishman, Wong, Elisabeth A., Wylie, John, Yang, Anna, Yao, Xuan, Yesodharan, Gemini, Yeung, Jennifer, Yin, Chun H., Yip, Agustin G., Yu, Diana H., Yu, Elizabeth An, Yung, Jeffrey, Zainelabdin, Sarah, Zambrano, Juliana, Zargarian, Emin, Zha, B. Shoshana, Zhang, Helen, Zhao, Leon, Zhou, Diana X., Ziaie, Navid, and Zorin, Danylo

Published
2025
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22. Progressive discoloration over the right shoulder

Author

Helm, Matthew F., Cole, David, and Seiverling, Elizabeth V.

Subjects
Children -- Diseases, Health
Abstract

The discolored patch on our patient's shoulder was nothing new--but when it grew in size and developed hypertrichosis, it prompted a closer investigation. A 15-year-old Caucasian boy presented for evaluation [...]

Published
2018

25. Keratinocytes and immune cells in the epidermis are key drivers of inflammation in hidradenitis suppurativa providing a rationale for novel topical therapies.

Author

Schell, Stephanie L, Cong, Zhaoyuan, Sennett, Mackenzie L, Gettle, Samantha L, Longenecker, Amy L, Goldberg, Stephanie R, Kirby, Joslyn S, Helm, Matthew F, and Nelson, Amanda M

Subjects
KERATINOCYTES, KILLER cells, HIDRADENITIS suppurativa, EPIDERMIS, POLYMERASE chain reaction, INFLAMMATION
Abstract

Background Hidradenitis suppurativa (HS) is a debilitating inflammatory skin disease characterized by painful nodules, drainage and scarring in skin folds. Injectable adalimumab is the only drug approved by the US Food and Drug Administration for the treatment of HS. Although systemic Janus kinase (JAK) inhibitors show promise, serious side-effects have been reported. There are no highly effective topical treatments for HS; furthermore, the contribution of epidermal keratinocytes to the intense inflammation has largely been unexplored. Objectives We investigated the role of keratinocytes and epidermal immune cells in HS inflammation at all Hurley stages of disease severity. We aimed to determine whether ruxolitinib can mitigate inflammation from keratinocytes and to develop a better understanding of how topical therapeutics might benefit patients with HS. Methods We used skin samples from 87 patients with HS (Hurley stages I–III) and 39 healthy controls to compare keratinocyte- and immune cell-driven epidermal inflammation, in addition to the response of lesional HS keratinocytes to treatment with interferon (IFN)-γ and ruxolitinib. We used haematoxylin and eosin staining, immunohistochemistry, immunoblotting and quantitative reverse-transcription polymerase chain reaction assessments in whole skin, isolated epidermis, and cultured keratinocytes from healthy controls and both nonlesional and lesional HS skin to identify and define epidermal and keratinocyte-mediated inflammation in HS and how this may be targeted by therapeutics. Results HS lesional keratinocytes autonomously secreted high levels of chemokines, such as CCL2, CCL3 and CXCL3, which recruited neutrophils, CD8 T cells, and natural killer cells to the epidermis. Keratinocytes were the dominant source of tumour necrosis factor-α and interleukin (IL)-6 in HS lesions with little to no contribution from underlying dermal immune cells. In the presence of IFN-γ, which is dependent on immune cell infiltrate in vivo , keratinocytes expressed increased levels of additional cytokines including IL-1β, IL-12, IL-23 and IL-36γ. The JAK inhibitor ruxolitinib mitigated the expression of inflammatory cytokines and chemokines in HS lesional keratinocytes, thus providing a rationale for future study as a topical treatment for HS. Conclusions This study demonstrates that keratinocytes actively recruit immune cells to HS epidermis and interactions between these cells drive a broad inflammatory profile in HS epidermis. Targeting epidermal inflammation in HS with novel topical formulations may be highly efficacious with reduced systemic side-effects. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Impact of trainee experience on shave biopsy specimen size.

Author

Dougher, Meaghan C., Butt, Melissa, Helm, Klaus F., and Helm, Matthew F.

Subjects
BIOPSY, ELECTRONIC health records, SKIN biopsy, ELECTRONIC systems, SHAVING
Abstract

Background: Skin biopsies are crucial for the diagnosis of many cutaneous pathologies, yet specimen adequacy is essential for definitive diagnosis. Recent literature has noted a trend in decreasing biopsy size over time, which has created concern over implications regarding adequacy for diagnosis. Methods: This study sought to evaluate if clinician training length or type of residency training impacted the average biopsy size and sample adequacy. Dermatopathology reports for shave biopsies between January 1, 2021, and June 30, 2021, at Penn State Health were queried through PathNet, the software application for pathology reports in this health system's electronic medical record system. Biopsy dimensions, volume, diagnosis, location, clinician training level, and descriptions of evaluation of deeper sections (recuts) and superficial sampling were recorded for each biopsy. Basic statistical calculations were performed to assess the mean and standard deviation for biopsy sizes per clinician group. Results: Differences in biopsy size between training levels were statistically significant despite qualitatively similar biopsy locations and final diagnosis categories for each clinician training group. After evaluating measures for sample adequacy, our data showed significantly smaller biopsies; however, overall frequencies were minimal. Additionally, more inadequate specimens were noted for clinician groups with the least amount of dermatology experience. Conclusions: The results of this study identify a correlation with decreasing biopsy size amidst increased experience in dermatology training but find no evidence to support that this trend currently threatens sample adequacy. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Dermoscopy in Primary Care

Author

Pokhrel, Prabhat K., primary, Helm, Matthew F., additional, Greene, Amrit, additional, Helm, Leesha A., additional, and Partin, Michael, additional

Published
2022
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30. Enlarging Pigmented Lesion on the Thigh.

Author

Dougher, Meaghan C., Helm, Thomas, and Helm, Matthew F.

Subjects
THIGH, MEDICAL communication, STAPHYLOCOCCUS aureus infections, TOTAL knee replacement
Abstract

The article focuses on diagnosing an enlarging pigmented lesion on a patient's thigh. It mentions the differential diagnosis includes various neoplasms, pigmented fungal infections, and cutaneous deposits due to systemic or topical medications or other exogenous substances. It highlights the final diagnosis is localized cutaneous argyria, a rare skin disorder resulting from silver deposition.

Published
2023
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31. Contributors

Author

Abdelazeem, Mohamed A., Abelman, Rebecca A., Kar, Sarah Abu, Afari, Maxwell Eyram, Ahmad, Ali, Ahmed, Hammood, Ahn, Benjamin J., Ahn-Horst, Rosa, Akoto, Shanice, AlAbdulhadi, Abrar, Aldras, Yoseph A., Ali, Fahad, Ali, Tanya, Alipanah-Lechner, Narges, Altunel, Erdem, Alzoebie, Lama, Anderson, Chelsie, Andrews, Christine B., Taylor, Kathryn Maire, Anthony, Anngene, Asaro, Joseph A., Asiedu, Daniel K., Astsaturov, Artem, Aulakh, Sudeep K., Authement, Matthew, Avasare, Rupali S., Babar, Tania B., Bachman, Emelia Argyropoulos, Baig, Muhammad, Bains, Ashika, Balaguera, Pedro, Balda, Javier, Bank, T. Caroline, Banwell, Brenda, Basman, Craig L., Bass, Crystal T., Bayefsky, Sarah D., Beausang, Jasjit, Belcher, Ren, Bell, Jennifer, Bellinghausen, Amy L., Bennett, Colleen E., Benninger, John W., Bergen, Michael A., Berger, Agatha, Berkowitz, Carol D., Berkowitz, Julia, Betageri, Omkar, Bhagat, Vicky H., Bharmal, Murtaza, Bhatt, Harikrashna B., Bhuptani, Prachi H., Bido-Medina, Richard O., Bielak, Kendall M.H., Bilodeau, Courtney Clark, Bird, Lisa, Bishop, Erin, Bitar, Ghamar, Blakeney, Craig, Block, Brian, Bochner, Risa, Bortz, Christina M., Bosse, Kristopher R., Bouton, Tara C., Bove, Mary E., Bowlby, Lynn A., Brady, Mark F., Bratman, Russell E., Brennan, Keith, Brown, Austin K., Brown, Emily C.B., Bui, Eric, Burke, Christine, Butler, William, Byanova, Katerina L., Byra, Marcin, Callanan, Tucker C., Campbell, Taylor, Cantos, Adriana, Canty, Ethan, Canty, Katherine W., Caraganis, Andrew, Carpenter, Randy S., Carragee, Eugene, Carrel-Lammert, Meredith, Carter, Ashlie Sewdass, Casillas, Ernesto, Jr., Castaneda-Guarderas, Ana, Castillo, Jorge J., Chait, Daniel, Chan, Philip A., Chang, Kenny, Chapman, Arlene B., Chatterjee-Paer, Sudeshna, Chaudhary, Richard S., Cheng, Vicky, Chilcote, Daniel, Chofay, Dana Ricci, Chou, Jonathan, Chou, Stella T., Choudhury, Natasha, Choxi, Shivali, Chua, Winona, Chubb, Rhiannon E., Cinelli, Michael P., Claman, David, Clark, Grace V., Clark, Seth, Clarke, Nathan, Clebak, Karl T., Cleland, Derrick, Co, Michael Lawrenz, Cohen, Debbie L., Cohen, Lisa, Congdon, Morgan, Constantinou, Maria, Corley, James Earl, III, Cosgrove, Abigail, Craine, Rebecca, Cristofaro, Patricia, Cruz, Aristides I., Cunningham, Karlene, Curtin, Alicia J., Cusano, Joseph, D’Alessandro, Frank B., Dado, Lynn, Dalela, Deepansh, Das, Abhijit, DaSilva, Manuel F., Davis, Mackenzie, De La Garza, Carlos, DeDent, Alison, Deeb, Maya, DeJong, Tyler, Desrochers, Colette, Diaz, Joseph A., Dickherber, Jason L., Do, Toan, Doo, Kathleen, Dove, James H., Dubanchet, Alexandre, Duh-Leong, Carol, Dutta, Roop, Dworkin, Myles, Dyster, Timothy G., Ebert, Eric, Edmund, Joseph, Eggers, Erica, Eisenhower, Christine, Ellsworth, Pamela, Escamilla-Ocañas, César E., Espinosa, Patricio Sebastian, Esqueda, Marisol, Everly, Eileen, Faber, Mark D., Faber, Rachel, Facer, Evan, Fadale, Paul D., Farahvash, Benyamin, Farias, Michael J., Farkas, Jon, Farrand, Erica, Fay, Kevin, Hernandez, Samantha Fernandez, Fernandez-Robles, Carlos, Ferreira, Jason D., Ferri, Fred F., Ferri, Heather, Fischer, Staci A., Fiske, Hannah, Velez Florez, Maria Camila, Font, Cristina, Forbes, Kellie C., Forcier, Michelle, Ford, Sydney, Fort, Frank G., Fort, Glenn G., Freeman, Nancy, Frisch, Daniel R., Fru, Relindis Azenwi, Fullenkamp, Lynn C., Gaffney, Michael, Garcia, Paloma Jolin, Ge, Connie, Gesthalter, Yaron B., Ghimire, Anil, Gibson, Christopher, Gidwani, Nisha H., Gil, Joseph, Gold, Raphaela, Goldburt, Alla, Goldsmith, Corey Elam, Gangadhara Rao Golla, Maheswara Satya, Gomez, Alexander, Gomez Slagle, Helen B., Greenfield, Morgan, Grisham, Lindsey Anne, Gu, Joey, Guardino, Cara E., Gugerty, Lindsay, Gul, Fahad, Gultawatvichai, Patan, Gunning, Samantha, Guo, Averill, Guo, David, Gupta, Simran, Guttadauria, Brittany, Guzman, Herodes, Gwinn, Meghan, Hadden, Ryan, Hafeez, Muhammad Ubaid, Hall, Hayden, Hall, Sarah, Handa, Sajeev, Handler, Stacy N., Hanna, James, Hanna, John, Harbord, Nikolas, Hardacker, Kyle, Hardesty, Anna, Haribhakti, Nirav, Harris, Daniel J., Hartnett, Davis A., Hartvigsen, Nathan, Hawkins, Brian, Heinle, Rachel Wright, Helm, Leesha A., Helm, Matthew F., Herlevich, Thomas, Hermez, Klodia M., Hilliard, Ross W., Hladky, Katherine, Hodges, Ashley, Hoffman, Ryan, Hoffman, R. Scott, Hogan, Dawn, Holiman, Jennifer J., Holland, N. Wilson, Holton, Siri M., Homer, Benjamin J., Hook, Benjamin E., Howell, Cody, Hsu, Raymond, Huang, Laurence, Hull, Mariam, Hume, Anne L., Hussain, Zilla, Huynh, Donny V., Hyder, Sarah, Ibrahim, Zainab, Ingraham, Caitlin, Inman, Nicholas J., Insalaco, Louis F., Jain, Rishubh, Jain, Vanita B.D., Jain, Vipul V., Jamal, Fariha, Jani, Kaushal, Janigian, Robert H., Jr., Jasuja, Sonia, Javier, Noelle Marie, Jetty, Vybhav, Johnson, Jennie E., Johnson, Michael P., Johnson, Steven D., Jolly, Angad, Jones, Amanda, Joshi, Shyam, Joudi, Kareem, Justice, Joshua, Kaddis, Timothy, Kalligeros, Markos, Karim, Omar, Karthikeyan, Vanji, Kartub, Benjamin, Kasper, Vania, Kass, Joseph S., Kass, Naomi R., Kasthuri, Viknesh S., Katz, Luca, Kaul, Bhavika, Kaur, Arpanjeet, Keim, Jennifer L., Keleshian, Vasken, Keogh, Abigail, Keselman, Dennis, Khan, Adeeba, Khare, Sarthak, Khawaja, Hussain R., Khetpal, Vishal, Khurana, Saranya S., Kifle, Betelhem, Kyung (Ellen) Kim, Eun, Kim, Jinseong, Kleitsch, Julianne, Knudson-Fitzpatrick, Tess, Kohrman, Samuel I., Kokkirala, Aravind Rao, Konstantino, Yuval, Kopyt, Nelson, Kothadia, Savan, Koti, Ajay, Koulouridis, Ioannis, Kreider, Timothy R., Krueger, Van S., Krumm, Ilana, Kumbar, Lalathaksha, Kuris, Eren O., Kurss, David I., L’Etoile, Nathan, Lam, Uyen T., Lam, William, Larijani, Mary, Le, Peter, Leard, Lorriana E., Leavitt, David A., Leba, Christopher T., Lee, Kachiu C., Lemme, Nicholas J., Li, Jian, Lieberman, Leora, Lim, Carol, Lin, Jason, Lippincott, Jordan, Liu, Jonathan, Logue, Teresa C., López, Gabriela, Lord, Kito Akin, Lucas, Mathew J., Lucier, David J., Jr., Ma’ayeh, Marwan, Maclean, Rachel L., MacMurdo, Maeve G., Madva, Elizabeth N., Mahani, Sahar, Makai, Gretchen, Malpica, Luis, Marcaccio, Stephen E., Marques Pinheiro, Ana Paula, Mazzaglia, Peter J., Mbuyi, Nadine N., McCulloh, Russell J., McDonald, Christopher L., McDonald-McGinn, Donna M., McGowen, Alexandra, McGraw, Katherine Elizabeth, McKenna, Jaclyn, McNamara, Kelly, Mead, Kelly C., Meehan, Caroline P., Meghani, Ozair K., Meleveedu, Kapil S., Mendez, Dianelys, Mendez-Miller, Megan, Mercado, Jorge, Mercado, Osvaldo, Merrill, Scott J., Merritt, Rory, Michaels, Marian G., Michel, Jeremy, Mikolasko, Brian D., Milner, John D., Min, May, Minami, Taro, Mitsuyama, Rei, Miyares, Laura, Mogla, Ankur, Mojarrab, Javad Najjar, Montgrain, Philippe, Moore, Michael Z., Moore, Shawn D., Morelli, Leah, Morrissey, Patrick J., Mughal, Aleem I., Mukkamalla, Shiva Kumar R., Mullersman, Katherine M., Mumtaz, Ahmad, Muraina, Fadeke, Mustafa, Ahmad, Myers, Ellen, Mylhousen, Emily, Nadella, Akash, Nadella, Mohnish, Nagpal, Nikita, Nandi, Minesh, Nasir, Uzma, Nasr, George H., Naveed, Asim, Neff, Robert, Neithardt, Adrienne B., Nelin, Timothy, Nestlerode, Christina, Ni, Samantha, Niazi, Azfar K., Nichols, Jonathan, Nokoff, Natalie, Noorbhai, Ibrahim Z.D., Novak, James E., Novarra, Austin, Nuss, Emily E., Oliver, Rebecca, Olszewski, Adam J., Onyeaka, Henry K., Orchowski, Lindsay M., Outlaw, Jasmine, Owens, Brett D., Oyelakin, Ayotomide, Pace, Paolo G., Palma-Zamora, Isaac, Pandya, Rachita, Pappas-Taffer, Lisa, Paranandi, Sneha, Parikh, Mihir, Park, Sara, Partin, Michael T., Patel, Birju B., Patel, Melissa D., Patel, Minta, Patel, Nima R., Patel, Pranav M., Patel, Vidhi, Patrick, Brett, Paudel, Shreedhar, Paxton, E. Scott, Peay, Celeste, Perazella, Mark A., Perez, David L., Hermina Perez, Jose J., Devon, Erin Pete, Pfeuti, Courtney, Pham, Lily C., Phelps-Polirer, Kendall, Phillips, Katharine A., Phillips, Oliver W., Phillips, Tara M., Piana, Lauren E., Portnoff, Brandon, Powell, Mitchell, Powers, Alexander, Prashar, Rohini, Premyodhin, Ned, Price, Dana, Priestley, Margaret, Provenza, Christian, Pulice, Christine, Punko, Diana, Puthawala, Imran, Qawi, Imrana, Qu, David, Quesada, Adrian, Quinn, Matthew, Rachu, Gregory S., Rajagopal, Amulya, Rathore, Bharti, Rathore, Ritesh, Raukar, Neha P., Ravindra, Lakshmi, Reagan, John L., Reardon, P.K., Reddy, Bharathi V., Reddy, Snigdha T., Reed-Weston, Anne, Reginato, Anthony M., Reichart, James P., Reus, Victor I., Rich, Harlan G., Rivera, Lauren Davis, Robertson, Melena J., Roby, Lauren, Roche, Meaghan, Morfin Rodriguez, Alejandra E., Romero Gómez, Perla M., Ron, Hayley A., Rosenbaum, Blake L., Rossi, Michael, Roussel, Breton, Rubin, David, Ruhstaller, Kelly, Rutstein, Beth H., Sadeghi, Noushine, Sahota, Ruchi Jalota, Saks, Emily, Sall, Jeffrey W., Salvi, Joshua D., Sanchez, Frank, Sanchez, Martha C., Sanka, Pranavi, Santhosh, Lekshmi, Santos, Linda Herrera, Sauck, Emily, Sayeed, Syeda M., Saylor, Leah, Schmitt, Phillip R., Sciscione, Anthony, Sederdahl, Bethany K., Seeber, Richard E., II, Sen, Aritra, Sewell, Rachel, Shaban, Hesham, Shah, Ankur, Shaikh, Aaron Ali, Sharma, Animesh, Sharma, Yuvraj, Sharp, Lydia, Sheikh, Wasiq, Sherman, Alexander, Shill, Jessica E., Shimanovsky, Alexei, Shlossman, Philip A., Siddiqui, Khawja A., Siegel, Alyssa, Sigman, Mark, Simon, Rebecca, Singh, Harinder P., Slingsby, Brett, Sloane, Amy, Smick, Alexandra H., Smith, Devon, Smith, Jeanette G., Smith, Matthew J., Sohaney, Ryann, Soi, Vivek, Soinski, Rebecca, Soler, Maria E., Soman, Sandeep, Song, Jeffrey S., Sorg, Emily, Sperati, C. John, Stanford, Nathan, Stennis, Seth Daly, Stephens, Michael S., Stern, Ella, Stockwell, Philip, Suh, Edward, Sun, Jennifer K., Sundaramoorthy, Anjali, Supanakorn, Varut, Suri, Priyasha, Sutter, Stephanie, Sweeney, Hannah, Takasaki, Kaoru, Takei, Ryosuke, Tan, Laren, Taylor, Alan, Taylor, Matthew, Taylor, S. Trevor, Tellioglu, Tahir, Testa, Edward J., Thomas, Anthony G., Thompson, Stefani, Tien, Alexandra Meyer, Tien, David Robbins, Tierney, Anna-Marie, Tiffany, Patrick, Toma, Helen, Triplett, Thomas M., Tryforos, Margaret, Tsaban, Gal, Tschoe, Christine, Tucci, Joseph R., Turock, Julia, Uduman, Junior, Uiterwyk, Sean H., Ukaegbu, Rebecca, Umanath, Kausik, Vakili, Babak, Van Kirk, Emily, Vemula, Ridhima, Venado, Aida, Vijayakumar, Shilpa, Vollum, Kathryn G., Vorel, Ethan, Walson, Ifeanyi, Wang, Angela, Wang, Jarey H., Weekley, Manuel Shayne, Weinberg, Marc S., Wendolowski, Stephen, Westreich, Roi, Whitaker, Colin, Wilhoite, Morgan, Wilks, Andrew, Wilson, Annise, Winikor, Jared M., Wininger, Bryce, Winschel, Julia M., Wolpaw, Adam J., Wolpert, Marlene Fishman, Wu, Perry, Wylie, John, Yaguchi, Grace K., Yang, Anna, Yao, Xuan, Yaseen, Muhammad, Yee, Jerry, Yesodharan, Gemini, Yeung, Jennifer, Yin, Chun H., Yip, Agustin G., Yu, Elizabeth An, Zambrano, Juliana, Zenlea, Talia, Zha, B. Shoshana, Zhang, Helen, Zhao, Leon, Zhou, Diana X., Ziaie, Navid, Zollman, Joshua W., Zorin, Danylo, and Zurek, Olivia

Published
2024
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36. Extensive Erosions and Ulcerations on the Trunk and Extremities in a Neonate.

Author

Accetta, Julia L., Singh, Saachvir, Grover, Raminder K., and Helm, Matthew F.

Subjects
EPIDERMOLYSIS bullosa, NEWBORN infants, HERPES simplex, MULTINUCLEATED giant cells
Abstract

The article presents a case study of a neonate with extensive erosions and ulcerations on the trunk and extremities. It describes the clinical presentation, discusses the diagnostic evaluation including a biopsy and immunofluorescence staining, and provides the diagnosis of Dominant Dystrophic Epidermolysis Bullosa. It further focuses on the specific patient's case and provides insights into the diagnosis and management of the condition.

Published
2023
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39. Contributors

Author

Abdelazeem, Mohamed A., Abelman, Rebecca A., Abrantes, Tatiana F., Afari, Maxwell Eyram, Afarideh, Mohsen, Ahmad, Ali, Ahn-Horst, Rosa, Akoto, Shanice, AlAbdulhadi, Abrar, Albright, J. Alex, Sierra, Maria Aldana, Ali, Tanya, Alipanah-Lechner, Narges, Anderson, Chelsea Bloom, Anderson, Chelsie, Anilowski, Kathryn Taylor, Anthony, Anngene, Aoun, Joe, Asaro, Joseph A., Asemota, Daniel, Asiedu, Daniel K., Astsaturov, Artem, Aulakh, Sudeep K., Avasare, Rupali, Babar, Tania B., Bachman, Emelia Argyropoulos, Bains, Ashika, Balaguera, Pedro, Bank, T. Caroline, Banwell, Brenda, Basman, Craig L., Bass, Crystal T., Beausang, Jasjit, Belcher, Ren, Bell, Jennifer, Bellinghausen, Amy L., Bennett, Colleen E., Benson, Nicole M., Bergen, Michael, Berger, Agatha, Berkowitz, Carol D., Bevington, Kristin, Bhagat, Vicky H., Bharmal, Murtaza, Bhatt, Harikrashna B., Bhuptani, Prachi H., Bido-Medina, Richard O., Bielak, Kendall, Bilodeau, Courtney Clark, Bird, Lisa, Bishop, Erin, Bissonette, Stefani, Bitar, Ghamar, Black, Julia E., Blakeney, Craig, Bland, Lauren, Blankenhorn, Brad, Block, Brian, Bochner, Risa, Boduch, Abigail N., Bortz, Christina M., Bouton, Tara C., Bove, Mary E., Bowlby, Lynn A., Box, Amanda, Brady, Mark F., Bratman, Russell E., Brennan, Keith, Bridges, Amy, Brown, Austin K., Brown, Emily, Bui, Eric, Burke, Christine, Burstein, Eleanor, Butler, William, Byanova, Katerina L., Caffrey, A. Gwendolyn, Cahill, Kate, Callanan, Tucker C., Campbell, Taylor, Canty, Katherine W., Cao, Damon H., Caraganis, Andrew, Carpenter, Randy S., Carragee, Eugene, Carrel-Lammert, Meredith, Carter, Ashlie Sewdass, Casillas, Ernesto, Jr., Castellon, Chrystina, Castillo, Jorge J., Catana, Andreea M., Cerezo, Carolina S., Chan, Philip A., Chang, Jacqueline, Chapman, Arlene, Chatterjee-Paer, Sudeshna, Chen, Kevin, Cheng, Vicky, Chin, Robin, Chofay, Dana Ricci, Cholankeril, George, Cholankeril, Rosann, Chou, Jonathan, Chou, Stella T., Choudhury, Natasha, Choxi, Shivali, Christian, Cindy W., Chua, Winona, Claman, David, Clark, Seth, Clarke, Nathan, Clebak, Karl T., Lawrenz, Michael, Cohen, Debbie L., Cohen, Lisa, Cohoon, Travis J., Congdon, Morgan, Constantinou, Maria, Copelin, Eddie L., II, Corley, James Earl, III, Cosgrove, Abigail, Craine, Rebecca, Cristofaro, Patricia, Cruz, Aristides I., Cunningham, Karlene, Curtin, Alicia J., Cusano, Joseph, Dabiri, Ganary, Dado, Lynn, Daly, Gerard H., Dan, Joshua, Dang, Frances, Dash, Miriam E., Dasilva, Manuel F., Davis, Mackenzie, Dedent, Alison, DeJong, Tyler, Denninger, John, Deol, Bisman, Desrochers, Colette, Devon, Erin Pete, Diaz, Joseph A., Dickherber, Jason L., DiMaria, Stephen, Disilvestro, Kevin J., Dohlman, Thomas H., Domenichini, David J., Doo, Kathleen, Dove, James H., Dubanchet, Alexandre, Dudley, John, Dutta, Roop, Dwivedi, Shashank, Dyster, Timothy G., Edmund, Joseph, Eggers, Erica, Eickhoff, Evlyn, Eisenhower, Christine, Ellsworth, Pamela, England, Melissa, Epstein, Alan, Espinosa, Patricio Sebastian, Evanoff, Anastasia, Everly, Eileen, Faber, Mark D., Fabio, Mary, Facer, Evan, Fadale, Paul, Fagan, Matthew J., Fallon, Ryan T., Farkas, Jon, Farrand, Erica, Fay, Kevin, Fernandez-Robles, Carlos, Ferreira, Jason D., Ferreira, Kaio S., Ferri, Fred F., Ferri, Heather, Fischer, Staci A., Wolpert, Marlene Fishman, Forbes, Kellie C., Forcier, Michelle, Ford, Sydney, Fort, Frank G., Fort, Glenn G., Freeman, Nancy, Fricchione, Gregory L., Frisch, Daniel R., Fru, Relindis Azenwi, Gasga, Arturo, Gentile, Tatiana Londoño, Gesthalter, Yaron B., Ghergurovich, Jonathan M., Gibson, Christopher, Gidwani, Nisha H., Gil, Joseph, Gilek-Seibert, Katarzyna, Gitelmaker, Dimitri, Gold, Raphaela, Goldburt, Alla, Goldfarb, Danielle, Goldsmith, Corey Elam, Gangadhara Rao Golla, Maheswara Satya, Gomez, Alexander, Gomez Slagle, Helen B., Gordon, Paul, Gorman, Deirdre C., Greenfield, Morgan, Grisham, Lindsey Anne, Guardino, Cara, Gultawatvichai, Patan, Guo, David, Gupta, Priya Sarin, Guttadauria, Brittany, Guzman, Herodes, Hack, Nawaz K.A., Hafeez, Muhammad Ubaid, Hajmohamed, Sherine, Hall, Sarah, Hallstead, Serica J., Handa, Sajeev, Handler, Stacy N., Harbord, Nikolas, Hardy, Erica J., Haribhakti, Nirav, Hartnett, Davis A., Hartvigsen, Nathan, Havele, Sonia A., Hawkins, Brian, Heinle, Rachel Wright, Helm, Leesha A., Helm, Matthew F., Hennebery, Ruth B., Herek, Jyothsna I., Hladky, Katherine, Hmoud, Hosam, Hodges, Ashley, Hoffman, R. Scott, Hogan, Dawn, Holderread, Brendan, Holiman, Jennifer J., Holland, N. Wilson, Holmes, Karima A., Holton, Siri M., Hsu, Raymond, Huang, Elena, Huang, Laurence, Hull, Mariam, Hume, Anne L., Hussain, Zilla, Hutchinson, Anne, Huynh, Donny V., Hyder, Sarah, Ibrahim, Zainab, Ingraham, Caitlin, Inman, Nicholas J., Innes, Brendan, Insalaco, Louis F., Isennock, Christopher, Ivkovic, Ana, Jafri, S. Hammad, Jain, Koyal, Jain, Vanita B.D., Jain, Vipul V., Jamal, Fariha, Jamil, Marcus L., Jamil, Nadia, Janigian, Robert H., Jr., Jasuja, Sonia, Javier, Noelle Marie, Jetty, Vybhav, Johl, Michael, Johnson, Michael P., Johnson, Steven D., Jolly, Angad, Jonas, Rebecca, Joshi, Shyam, Justice, Joshua, Kansara, Tikal, Karthikeyan, Vanji, Kass, Joseph S., Kass, Naomi R., Katarincic, Julia, Kaul, Bhavika, Kaur, Gurmehr, Kavandi, Hadiseh, Keleshian, Vasken, Keogh, Abigail, Kerrigan, Danielle, Keselman, Dennis, Khan, Adeeba, Khan, Rizwan, Khare, Sarthak, Khawaja, Hussain R., Ellen Kim, Eun Kyung, Kirchner, Robert M., Kodra, Arber, Kogan, Lawrence, Kohrman, Samuel I., Kojic, Erna Milunka, Kokkirala, Aravind Rao, Konstantino, Yuval, Kopyt, Nelson, Kosinski, Lindsay R., Kothadia, Savan, Koti, Ajay, Koulouridis, Ioannis, Kovacevic, Natalija, Kreider, Timothy R., Krishnamohan, Prashanth, Krueger, Van S., Kukreja, Mohit, Kumbar, Lalathaksha, Kuris, Eren O., Kurss, David I., Kutschke, Michael, L’Etoile, Nathan, Lacasce, Ann S., Lam, Uyen T., Lama, Christopher J., Lapite, Ajibike, Lau, Julianna, Leard, Lorriana E., Leavitt, David A., Leba, Christopher T., Lee, Kachiu C., Lee, Yvonne, Lemme, Nicholas J., Lento, René, Li, Jian, Lieberman, Leora, Lin, Erica, Lipner, Kaitlin, Lippincott, Jordan, Liu, Jonathan, London, Stephanie, López, Gabriela, Lord, Kito Akin, Lee Lowery, Curtis (Trey), III, Lucier, David J., Jr., Luther, Lauren, Ma’ayeh, Marwan, Maciag, Michelle C., MacKrell, Katherine, Maclean, Rachel L., MacMurdo, Maeve G., Madva, Elizabeth N., Makai, Gretchen, Makiyil, Jaibel, Malcolm, Katherine, Marcaccio, Stephen E., Marino, Daniel, Masaki, Charles, Mataya, Leslie, Matson, Kelly L., Mazzaglia, Peter J., Mbuyi, Nadine, McCrae, Brian, Jr., McCulloh, Russell J., McDonald, Christopher L., McGowen, Alexandra, McGuire, Leah, McGuirk, Barbara, McKenna, Jaclyn, McNamara, Kelly, Bido Medina, Richard Oliver, Meghani, Ozair K., Mercado, Jorge, Merrill, Scott J., Merritt, Rory, Metcalfe-Klaw, Robin, Michaels, Marian G., Michel, Jeremy, Midha, Shonali, Mikolasko, Brian D., Milner, John, Minami, Taro, Mitsuyama, Rei, Modest, Jacob M., Monhollon, Ethan, Montgrain, Philippe, Morelli, Leah, Morrissey, Patrick J., Mughal, Aleem I., Mukkamalla, Shiva Kumar R., Mullersman, Katherine M., Myers, Ellen, Mylhousen, Emily, Nadeem, Omar, Najem, Catherine E., Nandi, Minesh, Nasir, Uzma, Naveed, Asim, Neff, Robert, Neithardt, Adrienne B., Nelin, Timothy, Nestlerode, Christina, Ni, Samantha, Nokoff, Natalie, Novak, James E., Al Nuaimi, Saif K., Nuss, Emily E., O’Donnell, Ryan M., Oliver, Rebecca, Olszewski, Adam J., Onderko, Laura, Onyeaka, Henry K., Orchowski, Lindsay M., Osborne, Ashley D., Ovide, Gerry, Owens, Brett D., Oyelakin, Ayotomide, Pace, Paolo G., Palma-Zamora, Isaac, Papaila, Alexa, Pappas-Taffer, Lisa, Parekh, Maria A., Pares, Marco, Parikh, Mihir, Parikh, Shivani, Partin, Michael T., Patel, Birju B., Patel, Devan D., Patel, Melissa D., Patel, Nima R., Patel, Pranav M., Patrick, Brett, Pattni, Chandni, Paudel, Shreedhar, Paul, Ritika, Paxton, E. Scott, Peay, Celeste, Perazella, Mark, Perez, Alyssa, Perez, David L., Pfeuti, Courtney, Pham, Lily C., Pham, Long, Phillips, Katharine A., Phillips, Oliver W., Piana, Lauren E., Plante, Wendy A., Plumley, Kevin V., Powell, Mitchell, Powers, Alexander, Prashar, Rohini, Priestly, Margaret, Pulice, Christine, Punko, Diana, Puthawala, Imran, Qawi, Imrana, Quesada, Adrian, Rachu, Gregory S, Radhakrishnan, Parvathi, Raducha, Jeremy E., Rafeq, Samaan, Ranieri, Gina, Rathore, Bharti, Rathore, Ritesh, Raukar, Neha P., Reagan, John L., Reddy, Bharathi V., Reddy, Snigdha T., Reed-Weston, Anne, Reginato, Anthony M., Reichart, James P., Reinhart, Michaela B., Restrepo, Judith A., Reus, Victor I., Rich, Harlan G., Riotto, Giancarlo, Rivera, Alvaro M., Rivera, Lauren Davis, Roberts, Todd F., Robertson, Melena J., Roche, Meaghan, Rodarte, Patricia, Morfin Rodriguez, Alejandra E., Romero Gómez, Perla M., Roof, Tucker J., Rosenbaum, Blake L., Roussel, Breton, Rubeor, Amity, Rubin, David, Ruhstaller, Kelly, Sadeghi, Noushine, Saeed, Firrah, Sahota, Ruchi Jalota, Saks, Emily, Sall, Jeffrey W., Salvi, Joshua D., Samaniego-Picota, Milagros, Santhosh, Lekshmi, Santos, Linda Herrera, Satpathy, Hemant K., Satpathy, Ruby K., Sauck, Emily, Sayeed, Syeda M., Saylor, Leah, Scaramangas-Plumley, Daphne, Scheel, Paul J., Jr., Schlussel, Bradley, Schmitt, Heiko, Schnitzer, Kristina, Sciscione, Anthony, Scott, Matthew Thomas, Seeber, Richard E., II, Seijo, Leslie, Selby, Sasha L., Sell, Peter J., Sewell, Rachel, Shaban, Hesham, Shah, Ankur, Ali Shaikh, Aaron, Sharma, Animesh, Sharma, Yuvraj, Sharp, Lydia, Shea, Timothy, Sherman, Alexander, Shill, Jessica E., Shimanovsky, Alexei, Shlossman, Philip A., Siddiqui, Khawja A., Siegel, Alyssa, Sigman, Mark, Silber, Zachary S., Singh, Harinder P., Singhal, Divya, Sittard, Lauren, Slingsby, Brett, Sloane, Amy, Smick, Alexandra H., Smith, Devon, Smith, Jeanette G., Smith, Matthew J, Shain, Rachel Smith, Sohaney, Ryann, Soi, Vivek, Soinski, Rebecca, Soler, Maria E., Soman, Sandeep, Song, Jeffrey S., Sorg, Emily, Sperati, C. John, Sprow, Grant, Stern, Diana, Stern, Ella, Stockwell, Philip, Suh, Edward, Sun, Jennifer K., Sundaramoorthy, Anjali, Suppogu, Nissi, Sutter, Stephanie, Sweeney, Hannah, Tabatabavakili, Sahar, Tabba, Maher, Takasaki, Kaoru, Takei, Ryosuke, Talley-Bruns, Rachel, Tammaro, Dominick, Tan, Laren, Taylor, Alan, Taylor, S. Trevor, Tellioglu, Tahir, Testa, Edward J., Thomas, Anthony G., Tibbetts, Erin, Tien, Alexandra Meyer, Tien, David Robbins, Tierney, Anna-Marie, Tiffany, Patrick, Tillquist, Kristen, Toma, Helen, Triplett, Thomas M., Trivedi, Hirsh D., Tryforos, Margaret, Tsaban, Gal, Tucci, Joseph R., Turco, David, Turock, Julia, Tyree, Griffin A., Uduman, Junior, Uiterwyk, Sean H., Ukaegbu, Rebecca, Umanth, Kausik, Vakili, Babak, van Kirk, Emily, Vemula, Ridhima, Venado, Aida, Vijayakumar, Shilpa, Vollum, Kathryn G., Vorel, Ethan, Wagner, Brent T., Walesko, Mary-Beth, Walsh, Devin, Walsh, Ryan, Walson, Ifeanyi, Wang, Angela, Wang, Danielle, Wang, Jarey H., Wang, Stephani C., Wang, Tisha, Weinberg, Marc S., Westreich, Roi, Wilhoite, Morgan, Wilson, Annise, Wilson, Joshua, Winikor, Jared M., Wininger, Bryce, Winokur, Daniel, Wutawunashe, Caleb V., Wylie, John, Xiao, Yasi, Xu, Jennifer, Yang, Anna, Yarimi, Jonathan M., Yee, Jerry, Yesodharan, Gemini, Yeung, Jennifer, Yin, Chun H., Yip, Agustin G., Young, John Q., Young, Shane, Yu, Elizabeth An, Zenlea, Talia, Zha, B. Shoshana, Ziaie, Navid, Zipursky, Rachel, Zollman, Joshua W., Zorin, Danylo, and Zurek, Olivia

Published
2023
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49. Inadvertent intravascular injection of hyaluronic acid following osteoarthritis treatment: A rare but important complication to recognize.

Author

Shamloul, Norhan, Kamrani, Payvand, Horissian, Mikael, Helm, Matthew F., Cartee, Todd V., and Hollins, Lauren C.

Subjects
HYALURONIC acid, INTRA-articular injections, OSTEOARTHRITIS, INJECTIONS, HYALURONIDASES, KNEE pain, DERMATOLOGISTS
Abstract

This article discusses a rare but important complication that can occur following the injection of hyaluronic acid (HA) for osteoarthritis treatment. HA is commonly used in dermatology for skin augmentation and also provides lubrication for joints. In this case, a patient developed retiform purpura and skin necrosis after an inadvertent injection of HA into an artery in the knee. The patient was treated with hyaluronidase and other medications, and her symptoms improved. This case highlights the need for dermatologists to be aware of potential complications with HA injections and emphasizes the importance of understanding anatomy when performing these procedures. [Extracted from the article]

Published
2024
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50. Genital Lentiginosis: A Benign Pigmentary Abnormality Often Raising Concern for Melanoma.

Author

Albert, Nathan M., Gaddi, Andrew, Klawonn, Meghan A., Helm, Leesha, and Helm, Matthew F.

Subjects
LENTIGO, LICHEN sclerosus et atrophicus, VITILIGO, LICHEN planus, HUMAN abnormalities, MELANOMA
Abstract

The article presents a case study of 64-year-old woman who was referred by her gynecologist to dermatology to rule out vulvar melanoma. She had history of hypothyroidism and hypercholesterolemia; Genital examination revealed asymptomatic pigmented macules and patches of unknown duration and diagnostic studies revealed Genital lentiginosis.

Published
2022
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