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1. AB1701 IS THERE A DIFFERENCE IN THE NUMBER OF INVOLVED ORGAN SYSTEMS BETWEEN JUVENILE DIFFUSE AND LIMITED SUBTYPE SYSTEMIC SCLEROSIS PATIENTS?

Author

Foeldvari, I., primary, Klotsche, J., additional, Torok, K., additional, Kasapcopur, O., additional, Adrovic, A., additional, Feldman, B., additional, Antón, J., additional, Johnson, S. R., additional, Sztajnbok, F. R., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Khubchandani, R., additional, Stanevicha, V., additional, Schonenberg, D., additional, Al-Abadi, E., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Malcova, H., additional, Marrani, E., additional, Pain, C., additional, Patwardhan, A., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Abu Al Saoud, S., additional, Costa Reis, P., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Sparchez, M., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2024
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2. POS0758 PRESENCE OF NAILFOLD CAPILLARY CHANGES CORRELATES WITH MORE SEVERE ORGAN INVOLVEMENT IN JUVENILE SYSTEMIC SCLERODERMA. RESULTS OF THE JUVENILE SCLERODERMA INCEPTION COHORT.

Author

Foeldvari, I., primary, Klotsche, J., additional, Torok, K., additional, Kasapcopur, O., additional, Adrovic, A., additional, Feldman, B., additional, Antón, J., additional, Johnson, S. R., additional, Sztajnbok, F. R., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Stanevicha, V., additional, Schonenberg, D., additional, Alexeeva, E., additional, Katsikas, M., additional, Khubchandani, R., additional, Sawhney, S., additional, Smith, V., additional, Al-Abadi, E., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Malcova, H., additional, Marrani, E., additional, Pain, C., additional, Patwardhan, A., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Abu Al Saoud, S., additional, Costa Reis, P., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Sparchez, M., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2024
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3. POS0770 DIFFERENCES IN CLINICAL PRESENTATION BETWEEN JUVENILE SYSTEMIC SCLEROSIS PATIENTS WITH DIFFUSE AND LIMITED SUBTYPE. RESULTS FROM THE JUVENILE SCLERODERMA INCEPTION COHORT.

Author

Foeldvari, I., primary, Klotsche, J., additional, Torok, K., additional, Kasapcopur, O., additional, Adrovic, A., additional, Feldman, B., additional, Antón, J., additional, Johnson, S. R., additional, Sztajnbok, F. R., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Khubchandani, R., additional, Stanevicha, V., additional, Schonenberg, D., additional, Al-Abadi, E., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Malcova, H., additional, Marrani, E., additional, Pain, C., additional, Patwardhan, A., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Abu Al Saoud, S., additional, Costa Reis, P., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Sparchez, M., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2024
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4. HOW CHATBOTS’ SOCIAL PRESENCE COMMUNICATION ENHANCES CONSUMER ENGAGEMENT, BRAND LIKABILITY, INTERACTION SATISFACTION: THE MEDIATING ROLE OF INITIAL CHATBOTS’ TRUST

Author

Kumala C., Nuraini D., Helmus N., and Masnita Y.

Subjects
chabots’ social presence communication, consumer engagement, brand likability, interaction satisfaction, initial chatbots’ trust, artificial intelligence, Agriculture (General), S1-972
Abstract

The growing importance of chatbots as interactive communication channels is changing the way businesses approach marketing. Unlike previous chatbot studies that focused on the utilitarian use of chatbots for online customer support, this research not only looks at which aspects of chatbot communication and profile design may drive chatbot effectiveness, but it also looks at the mechanism underlying the messaging and design effects on consumer engagement. Purpose of this study was to investigates the link between social communication tools in the form of chatbots and consumer confidence in chatbots, as well as their impact on customer reaction, with an emphasis on user engagement mediated by the initial trust factor of chatbots. This study used quantitative research confirmatory factors analysis using Structural Equation Modeling (SEM). The sampling method used in this research is purposive sampling with number of samples are 258 respondents in Jabodetabek. The findings showed that social presence communication has a positive influence on intial chatbot trust, initial chatbot trust has a postibe influence on brand likability, user engagement, and interaction satisfaction, and also initial chatbots’ trust bringing positive influence on mediating user engagement, interaction satisfaction, and brand likability. AI applications, specifically chatbots in marketing, as an interpersonal communication is an important tools to increase consumer engagement. From this study also can be provides crucial strategic advice to assist marketers use the conversational potential of chatbots for brand communication, based on the empirical findings.

Published
2022

5. POS0139 DIFFUSE JUVENILE SYSTEMIC SCLEROSIS PATIENTS SHOW DISTINCT ORGAN INVOLVEMENT, ANTIBODY PATTERN AND HAVE SIGNIFICANTLY MORE SEVERE DISEASE IN THE LARGEST JSSC COHORT OF THE WORLD. RESULTS FROM THE JUVENILE SCLERODERMA INCEPTION COHORT

Author

Foeldvari, I., primary, Klotsche, J., additional, Torok, K., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Sztajnbok, F. R., additional, Antón, J., additional, Stanevicha, V., additional, Johnson, S., additional, Khubchandani, R., additional, Schonenberg, D., additional, Al-Abadi, E., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Malcova, H., additional, Marrani, E., additional, Pain, C., additional, Patwardhan, A., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Costa Reis, P., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Santos, M. J., additional, Abu Al Saoud, S., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2023
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6. POS0140 PATIENT AND PHYSICIAN REPORTED OUTCOMES OF JUVENILE SYSTEMIC SCLEROSIS PATIENTS SIGNIFICANTLY IMPROVE OVER 24 MONTHS OBSERVATION PERIOD IN THE JUVENILE SYSTEMIC SCLERODERMA INCEPTION COHORT

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Antón, J., additional, Feldman, B., additional, Khubchandani, R., additional, Kostik, M., additional, Lehman, T., additional, Marrani, E., additional, Katsikas, M., additional, Nemcova, D., additional, Santos, M. J., additional, Sztajnbok, F. R., additional, Appenzeller, S., additional, Battagliotti, C., additional, Berntson, L., additional, Brunner, J., additional, Harel, L., additional, Horneff, G., additional, Johnson, S., additional, Kallinich, T., additional, Minden, K., additional, Moll, M., additional, Nuruzzaman, F., additional, Patwardhan, A., additional, Schonenberg, D., additional, and Helmus, N., additional

Published
2023
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7. POS0141 APPLICATION OF CRISS SCORE, REVISED CRISS SCORE AND RCID SCORE IN PATIENTS WITH JUVENILE SYSTEMIC SCLEROSIS

Author

Klotsche, J., primary, Foeldvari, I., additional, Torok, K., additional, Del Galdo, F., additional, Furst, D., additional, Kasapcopur, O., additional, Adrovic, A., additional, Feldman, B., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Sztajnbok, F. R., additional, Antón, J., additional, Katsikas, M., additional, Stanevicha, V., additional, Appenzeller, S., additional, Avcin, T., additional, Johnson, S., additional, Kostik, M., additional, Malcova, H., additional, Marrani, E., additional, Sifuentes-Giraldo, W. A., additional, Khubchandani, R., additional, Nemcova, D., additional, Santos, M. J., additional, Schonenberg, D., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kallinich, T., additional, Lehman, T., additional, Minden, K., additional, Moll, M., additional, Nielsen, S., additional, Patwardhan, A., additional, Smith, V., additional, and Helmus, N., additional

Published
2023
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8. Application of CRISS score, revised CRISS score and RCID score in patients with Juvenile systemic sclerosis

Author

Klotsche, J, Foeldvari, I, Torok, K, Del Gado, F, Furst, DE, Kasapcopur, O, Adrovic, A, Feldman, B, Terreri, MT, Sakamoto, AP, Sztajnbok, F, Anton, J, Katsicas, M, Stanevicha, V, Appenzeller, S, Avcin, T, Johnson, S, Kostik, M, Malcova, H, Marrani, E, Sifuentes-Giraldo, WA, Khubchandani, R, Nemcova, D, Santos, MJ, Schonenberg, D, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kallinich, T, Lehman, T, Minden, K, Moll, M, Nielsen, S, Patwardhan, A, Smith, V, Helmus, N, Klotsche, J, Foeldvari, I, Torok, K, Del Gado, F, Furst, DE, Kasapcopur, O, Adrovic, A, Feldman, B, Terreri, MT, Sakamoto, AP, Sztajnbok, F, Anton, J, Katsicas, M, Stanevicha, V, Appenzeller, S, Avcin, T, Johnson, S, Kostik, M, Malcova, H, Marrani, E, Sifuentes-Giraldo, WA, Khubchandani, R, Nemcova, D, Santos, MJ, Schonenberg, D, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kallinich, T, Lehman, T, Minden, K, Moll, M, Nielsen, S, Patwardhan, A, Smith, V, and Helmus, N

Published
2023

9. Patient and physician reported outcomes of juvenile systemic sclerosis patients significantly improve over 24 months observation period in the juvenile systemic scleroderma inception cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Anton, J, Feldman, B, Khubchandani, R, Kostik, M, Lehman, T, Marrani, E, Katsicas, M, Nemcova, D, Santos, MJ, Sztajnbok, F, Appenzeller, S, Battagliotti, C, Berntson, L, Brunner, J, Harel, L, Horneff, G, Johnson, S, Kallinich, T, Minden, K, Moll, M, Nuruzzaman, F, Patwardhan, A, Schonenberg, D, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Anton, J, Feldman, B, Khubchandani, R, Kostik, M, Lehman, T, Marrani, E, Katsicas, M, Nemcova, D, Santos, MJ, Sztajnbok, F, Appenzeller, S, Battagliotti, C, Berntson, L, Brunner, J, Harel, L, Horneff, G, Johnson, S, Kallinich, T, Minden, K, Moll, M, Nuruzzaman, F, Patwardhan, A, Schonenberg, D, and Helmus, N

Published
2023

10. Diffuse juvenile systemic sclerosis patients show distinct organ involvement, antibody pattern and have significantly more severe disease in the largest jSSc cohort of the world. Results from the juvenile scleroderma inception cohort

Author

Foeldvari, I, Klotsche, J, Torok, K, Kasapcopur, O, Adrovic, A, Terreri, MT, Sakamoto, AP, Feldman, B, Sztajnbok, F, Anton, J, Stanevicha, V, Johnson, S, Khubchandani, R, Schonenberg, D, Al-Abadi, E, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Malcova, H, Marrani, E, Pain, C, Patwardhan, A, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Nemcova, D, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, Helmus, N, Foeldvari, I, Klotsche, J, Torok, K, Kasapcopur, O, Adrovic, A, Terreri, MT, Sakamoto, AP, Feldman, B, Sztajnbok, F, Anton, J, Stanevicha, V, Johnson, S, Khubchandani, R, Schonenberg, D, Al-Abadi, E, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Malcova, H, Marrani, E, Pain, C, Patwardhan, A, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Nemcova, D, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, and Helmus, N

Published
2023

11. Is decreased body mass index-2 z score or less correlating with an organ involvement pattern? Results from the juvenile scleroderma inception cohort

Author

Foeldvari, I, Klotsche, J, Torok, K, Kasapcopur, O, Adrovic, A, Feldman, B, Sztajnbok, F, Anton, J, Terreri, MT, Sakamoto, AP, Khubchandani, R, Stanevicha, V, Al-Abadi, E, Alexeeva, E, Katsicas, M, Sawhney, S, Schonenberg, D, Smith, V, Appenzeller, S, Avcin, T, Lehman, T, Malcova, H, Marrani, E, Patwardhan, A, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Johnson, S, Kostik, M, Nemcova, D, Pain, C, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, Helmus, N, Foeldvari, I, Klotsche, J, Torok, K, Kasapcopur, O, Adrovic, A, Feldman, B, Sztajnbok, F, Anton, J, Terreri, MT, Sakamoto, AP, Khubchandani, R, Stanevicha, V, Al-Abadi, E, Alexeeva, E, Katsicas, M, Sawhney, S, Schonenberg, D, Smith, V, Appenzeller, S, Avcin, T, Lehman, T, Malcova, H, Marrani, E, Patwardhan, A, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Johnson, S, Kostik, M, Nemcova, D, Pain, C, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, and Helmus, N

Published
2023

12. Diffuse juvenile systemic sclerosis patients show distinct organ involvement and have more severe disease in the largest jSSc cohort of the world. Results from the the juvenile scleroderma inception cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Sztajnbok, F, Stanevicha, V, Anton, J, Johnson, S, Khubchandani, R, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Malcova, H, Marrani, E, Pain, C, Schonenberg, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Sztajnbok, F, Stanevicha, V, Anton, J, Johnson, S, Khubchandani, R, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Malcova, H, Marrani, E, Pain, C, Schonenberg, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Costa Reis, P, Janarthanan, M, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, Abu Al-Saoud, S, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nuruzzaman, F, Opsahl Hetlevik, S, Uziel, Y, and Helmus, N

Published
2022

13. Juvenile systemic sclerosis treatment practices in an international cohort and comparison to recent SHARE consensus guidelines

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Anton, J, Sztajnbok, F, Stanevicha, V, Appenzeller, S, Avcin, T, Johnson, S, Khubchandani, R, Kostik, M, Marrani, E, Sifuentes-Giraldo, WA, Nemcova, D, Santos, MJ, Schonenberg, D, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Janarthanan, M, Kallinich, T, Lehman, T, Moll, M, Nuruzzaman, F, Patwardhan, A, Smith, V, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Anton, J, Sztajnbok, F, Stanevicha, V, Appenzeller, S, Avcin, T, Johnson, S, Khubchandani, R, Kostik, M, Marrani, E, Sifuentes-Giraldo, WA, Nemcova, D, Santos, MJ, Schonenberg, D, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Janarthanan, M, Kallinich, T, Lehman, T, Moll, M, Nuruzzaman, F, Patwardhan, A, Smith, V, and Helmus, N

Published
2022

14. Patient and physician reported outcomes of juvenile systemic sclerosis patients significantly improve over 12 months observation period in the juvenile systemic scleroderma inception cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Feldman, B, Anton, J, Katsicas, M, Stanevicha, V, Sztajnbok, F, Appenzeller, S, Avcin, T, Kostik, M, Marrani, E, Sifuentes-Giraldo, WA, Johnson, S, Khubchandani, R, Nemcova, D, Santos, MJ, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Janarthanan, M, Kallinich, T, Minden, K, Moll, M, Nielsen, S, Patwardhan, A, Schonenberg, D, Smith, V, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Feldman, B, Anton, J, Katsicas, M, Stanevicha, V, Sztajnbok, F, Appenzeller, S, Avcin, T, Kostik, M, Marrani, E, Sifuentes-Giraldo, WA, Johnson, S, Khubchandani, R, Nemcova, D, Santos, MJ, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Cimaz, R, Eleftheriou, D, Harel, L, Horneff, G, Janarthanan, M, Kallinich, T, Minden, K, Moll, M, Nielsen, S, Patwardhan, A, Schonenberg, D, Smith, V, and Helmus, N

Published
2022

15. POS0172 DIFFUSE JUVENILE SYSTEMIC SCLEROSIS PATIENTS SHOW DISTINCT ORGAN INVOLVEMENT AND HAVE MORE SEVERE DISEASE IN THE LARGEST jSSc COHORT OF THE WORLD. RESULTS FROM THE THE JUVENILE SCLERODERMA INCEPTION COHORT. www.juvenile-scleroderma.com

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Sztajnbok, F. R., additional, Stanevicha, V., additional, Anton, J., additional, Johnson, S., additional, Khubchandani, R., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Malcova, H., additional, Marrani, E., additional, Pain, C., additional, Schonenberg, D., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Costa Reis, P., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Patwardhan, A., additional, Santos, M. J., additional, Abu Al Saoud, S., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Cimaz, R., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2022
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16. POS1302 PATIENT AND PHYSICIAN REPORTED OUTCOMES OF JUVENILE SYSTEMIC SCLEROSIS PATIENTS SIGNIFICANTLY IMPROVE OVER 12 MONTHS OBSERVATION PERIOD IN THE JUVENILE SYSTEMIC SCLERODERMA INCEPTION COHORT. www.juvenile-scleroderma.com

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Anton, J., additional, Katsikas, M., additional, Stanevicha, V., additional, Sztajnbok, F. R., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Marrani, E., additional, Sifuentes-Giraldo, W. A., additional, Johnson, S., additional, Khubchandani, R., additional, Nemcova, D., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Cimaz, R., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Janarthanan, M., additional, Kallinich, T., additional, Minden, K., additional, Moll, M., additional, Nielsen, S., additional, Patwardhan, A., additional, Schonenberg, D., additional, Smith, V., additional, and Helmus, N., additional

Published
2022
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17. POS1299 JUVENILE SYSTEMIC SCLEROSIS TREATMENT PRACTICES IN AN INTERNATIONAL COHORT AND COMPARISON TO RECENT SHARE CONSENSUS GUIDELINES.

Author

Foeldvari, I., primary, Torok, K., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Anton, J., additional, Sztajnbok, F. R., additional, Stanevicha, V., additional, Appenzeller, S., additional, Avcin, T., additional, Johnson, S., additional, Khubchandani, R., additional, Kostik, M., additional, Marrani, E., additional, Sifuentes-Giraldo, W. A., additional, Nemcova, D., additional, Santos, M. J., additional, Schonenberg, D., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Cimaz, R., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Janarthanan, M., additional, Kallinich, T., additional, Lehman, T., additional, Moll, M., additional, Nuruzzaman, F., additional, Patwardhan, A., additional, Smith, V., additional, and Helmus, N., additional

Published
2022
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18. Patients with juvenile systemic sclerosis have a distinct pattern of organ involvement. Results from thejuvenile systemic sclerosis inception cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Stanevicha, V, Anton, J, Sztajnbok, F, Khubchandani, R, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Marrani, E, Schonenberg, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Janarthanan, M, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, and Helmus, N

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Introduction: Juvenile systemic sclerosis (jSSc) is a rare disease with a prevalence of around 3 in 1,000,000 children. To better capture the clinical manifestations of jSSc the juvenile systemic sclerosis inception cohort (jSScC, [link:https://www.juvenile-scleroderma.com/*https://www.juvenile-scleroderma.com/])[for full text, please go to the a.m. URL], Deutscher Rheumatologiekongress 2021, 49. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 35. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2021
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19. Differences sustained between diffuse and limited forms of juvenile systemic sclerosis in expanded international cohort. www.juvenile-scleroderma.com

Author

Foeldvari I, Klotsche J, Kasapcopur O, Adrovic A, Terreri MT, Sakamoto AP, Stanevicha V, Sztajnbok F, Anton-Lopez J, Feldman B, Alexeeva E, Katsicas M, Smith V, Avcin T, Marrani E, Kostik M, Lehman T, Sifuentes-Giraldo WA, Vasquez-Canizares N, Appenzeller S, Janarthanan M, Moll M, Nemcova D, Patwardhan A, Santos MJ, Sawhney S, Schonenberg-Meinema D, Battagliotti C, Berntson L, Bica B, Brunner J, Costa-Reis P, Eleftheriou D, Harel L, Horneff G, Kaiser D, Kallinich T, Lazarevic D, Minden K, Nielsen S, Nuruzzaman F, Uziel Y, Helmus N, and Torok KS

Abstract

OBJECTIVES: To evaluate the baseline clinical characteristics of juvenile systemic sclerosis (jSSc) patients in the international Juvenile SSc Inception Cohort (jSScC), compare these characteristics between the classically defined diffuse (dcjSSc) and limited cutaneous (lcjSSc) subtypes, and among those with overlap features. METHODS: A cross-sectional study was performed using baseline visit data. Demographic, organ system evaluation, treatment, and patient and physician reported outcomes were extracted and summary statistics applied. Comparisons between dcjSSc and lcSSc subtypes and patients with and without overlap features were performed using Chi-square and Mann Whitney U-tests. RESULTS: At data extraction 150 jSSc patients were enrolled across 42 centers, 83% were Caucasian, 80% female, dcjSSc predominated (72%), and 17% of the cohort had overlap features. Significant differences were found between dcjSSc and lcjSSc regarding the modified Rodnan Skin Score, presence of Gottron's papules, digital tip ulceration, 6 Minute walk test, composite pulmonary and cardiac involvement. All more frequent in dcSSc except for cardiac involvement. DcjSSc patients had significantly worse scores for physician rated disease activity and damage. A significantly higher occurrence of Gottron's papules, musculoskeletal involvement and composite pulmonary involvement, and significantly lower frequency of Raynaud's phenomenon, were seen in those with overlap features. CONCLUSION: Results from a large international jSSc cohort demonstrate significant differences between dcjSSc and lcjSSc patients including more globally severe disease and increased frequency of ILD in dcjSSc patients, while those with lcSSc have more frequent cardiac involvement. Those with overlap features had an unexpected higher frequency of interstitial lung disease.

Published
2021

20. Patients with Juvenile Systemic Sclerosis Have a Distinct Pattern of Organ Involvement: Results from the Juvenile Systemic Sclerosis Inception Cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, M, Sakamoto, AP, Sztajnbok, F, Feldman, B, Stanevicha, V, Anton-Lopez J, Khubchandani, R, Alexeeva, E, Johnson, S, Katsicas, MM, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Marrani, E, Schonenberg-Meinema, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Janarthanan, M, Malcova, H, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, Battagliotti, C, Berntson, L, Bica, BERG, Brunner, J, Cimaz, R, Reis, PC, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Hetlevik, SO, Uziel, Y, and Helmus, N

Published
2021

21. Male Juvenile Systemic Sclerosis Patients Have More Severe Disease: Results from the International Juvenile Scleroderma Inception Cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, M, Sakamoto, AP, Sztajnbok, F, Feldman, B, Stanevicha, V, Anton-Lopez J, Khubchandani, R, Alexeeva, E, Johnson, S, Katsicas, MM, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Marrani, E, Schonenberg-Meinema, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Janarthanan, M, Malcova, H, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, Battagliotti, C, Berntson, L, Bica, BERG, Brunner, J, Cimaz, R, Reis, PC, Eleftheriou, D, Harel, L, Horneff, G, Kaiser, D, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Hetlevik, SO, Uziel, Y, and Helmus, N

Published
2021

22. Juvenile systemic sclerosis (jSSc) patients with overlap characteristics do not have mild disease.Results from thejSSc inception cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Stanevicha, V, Anton, J, Sztajnbok, F, Khubchandani, R, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Marrani, E, Schonenberg, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Janarthanan, M, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Terreri, MT, Sakamoto, AP, Feldman, B, Stanevicha, V, Anton, J, Sztajnbok, F, Khubchandani, R, Alexeeva, E, Katsicas, M, Sawhney, S, Smith, V, Appenzeller, S, Avcin, T, Kostik, M, Lehman, T, Marrani, E, Schonenberg, D, Sifuentes-Giraldo, WA, Vasquez-Canizares, N, Janarthanan, M, Moll, M, Nemcova, D, Patwardhan, A, Santos, MJ, and Helmus, N

Published
2021

23. POS1304 JUVENILE SYSTEMIC SCLEROSIS (JSSC) PATIENTS WITH OVERLAP CHARACTERISTICS DO NOT HAVE MILD DISEASE. RESULTS FROM THE JSSC INCEPTION COHORT. WWW.JUVENILESCLERODERMA.COM

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Stanevicha, V., additional, Anton, J., additional, Sztajnbok, F. R., additional, Khubchandani, R., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Marrani, E., additional, Schonenberg, D., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Patwardhan, A., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Cimaz, R., additional, Costa Reis, P., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Johnson, S., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2021
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24. POS0079 PATIENTS WITH JUVENILE SYSTEMIC SCLEROSIS HAVE A DISTINCT PATTERN OF ORGAN INVOLVEMENT.RESULTS FROM THE JUVENILE SYSTEMIC SCLEROSIS INCEPTION COHORT. WWW.JUVENILE-SCLERODERMA.COM

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Feldman, B., additional, Stanevicha, V., additional, Anton, J., additional, Sztajnbok, F. R., additional, Khubchandani, R., additional, Alexeeva, E., additional, Katsikas, M., additional, Sawhney, S., additional, Smith, V., additional, Appenzeller, S., additional, Avcin, T., additional, Kostik, M., additional, Lehman, T., additional, Marrani, E., additional, Schonenberg, D., additional, Sifuentes-Giraldo, W. A., additional, Vasquez-Canizares, N., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Patwardhan, A., additional, Santos, M. J., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Cimaz, R., additional, Costa Reis, P., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Johnson, S., additional, Kaiser, D., additional, Kallinich, T., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Opsahl Hetlevik, S., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2021
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25. Under detection of interstitial lung disease in juvenile systemic sclerosis (jSSc)

Author

Foeldvari I, Klotsche J, Hinrichs B, Helmus N, Kasapcopur O, Adrovic A, Sztajnbok F, Terreri MT, Anton-Lopez J, Smith V, Katsicas M, Kostik M, Vasquez-Canizares N, Avcin T, Feldman B, Janarthanan M, Santos MJ, Sawhney S, Schonenberg-Meinema D, Sifuentes-Giraldo WA, Alexeeva E, Appenzeller S, Battagliotti C, Berntson L, Bica B, Costa Reis P, Eleftheriou D, Kallinich T, Lehman T, Marrani E, Minden K, Nielsen S, Nuruzzaman F, Patwardhan A, Khubchandani R, Stanevicha V, Uziel Y, and Torok KS

Subjects
respiratory system, behavioral disciplines and activities, respiratory tract diseases
Abstract

OBJECTIVES: Utilizing data obtained from a prospective international juvenile systemic sclerosis cohort (jSScC) to determine if pulmonary screening with forced vital capacity (FVC) and diffusing capacity of the lungs for carbon monoxide (DLCO) is sufficient to assess the presence of interstitial lung disease (ILD) in comparison to high resolution computed tomography (HRCT) in jSSc. METHODS: The jSScC cohort database was queried for patients enrolled from January 2008 to January 2020 with recorded pulmonary function tests (PFT) parameters and HRCT to determine the discriminatory properties of PFTs parameters, FVC and DLCO, in detecting ILD. RESULTS: Eighty-six jSSc patients had both CT imaging and FVC values for direct comparison. Using findings on HRCT as the standard measure of ILD presence, the sensitivity of FVC in detecting ILD in jSSc was only 40%, the specificity was 77%, and AUC was 0.58. Fifty-eight jSSc patients had both CT imaging and DLCO values for comparison. The sensitivity of DLCO in detecting ILD was 76%, the specificity was 70%, and AUC was 0.73. CONCLUSION: The performance of PFTs in jSSc to detect underlying ILD was quite limited. Specifically, the FVC, which is one of the main clinical parameters in adult SSc to detect and monitor ILD, would miss approximately 60% of children that had ILD changes on their accompanying HRCT. The DLCO was more sensitive in detecting potential abnormalities in HRCT, but with less specificity than the FVC. These results support the use of HRCT in tandem with PFTs for the screening of ILD in jSSc.

Published
2020

26. FRI0466 NO DISEASE PROGRESSION AFTER 36 MONTHS FOLLOW UP IN THE JUVENILE SYSTEMIC SCLERODERMA INCEPTION COHORT

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M. T., additional, Cimaz, R., additional, Katsikas, M., additional, Nemcova, D., additional, Santos, M. J., additional, Brunner, J., additional, Kostik, M., additional, Minden, K., additional, Patwardhan, A., additional, Torok, K., additional, and Helmus, N., additional

Published
2020
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27. SAT0500 HOW THE ADULT CRISS WORKS IN PEDIATRIC jSSc PATIENTS - RESULTS FROM THE JUVENILE SCLERODERMA INCEPTION COHORT

Author

Klotsche, J., primary, Foeldvari, I., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Stanevicha, V., additional, Anton, J., additional, Marrani, E., additional, Terreri, M. T., additional, Sztajnbok, F. R., additional, Battagliotti, C., additional, Berntson, L., additional, Eleftheriou, D., additional, Horneff, G., additional, Nuruzzaman, F., additional, and Helmus, N., additional

Published
2020
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28. THU0499 IS THERE A DIFFERENT PRESENTATION OF JUVENILE SYSTEMIC DIFFUSE AND LIMITED SUBSET? DATA FROM THE JUVENILE SCLERODERMA INCEPTION COHORT. WWW.JUVENILE-SCLEORDERMA.COM

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Stanevicha, V., additional, Sztajnbok, F. R., additional, Anton, J., additional, Feldman, B., additional, Alexeeva, E., additional, Katsikas, M., additional, Smith, V., additional, Marrani, E., additional, Kostik, M., additional, Vasquez-Canizares, N., additional, Appenzeller, S., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Patwardhan, A., additional, Santos, M. J., additional, Sawhney, S., additional, Schonenberg, D., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Costa Reis, P., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Kaiser, D., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2020
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29. FRI0454 UNDER DETECTION OF INTERSTITIAL LUNG DISEASE IN JUVENILE SYSTEMIC SCLEROSIS (JSSC) UTILIZING PULMONARY FUNCTION TESTS. RESULTS FROM THE JUVENILE SCLERODERMA INCEPTION COHORT

Author

Foeldvari, I., primary, Hinrichs, B., additional, Torok, K., additional, Santos, M. J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Stanevicha, V., additional, Sztajnbok, F. R., additional, Terreri, M. T., additional, Sakamoto, A. P., additional, Alexeeva, E., additional, Anton, J., additional, Katsikas, M., additional, Smith, V., additional, Cimaz, R., additional, Kostik, M., additional, Appenzeller, S., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Schonenberg, D., additional, Battagliotti, C., additional, Berntson, L., additional, Bica, B., additional, Brunner, J., additional, Costa Reis, P., additional, Eleftheriou, D., additional, Harel, L., additional, Horneff, G., additional, Lazarevic, D., additional, Minden, K., additional, Nielsen, S., additional, Nuruzzaman, F., additional, Patwardhan, A., additional, Uziel, Y., additional, and Helmus, N., additional

Published
2020
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30. Is there a difference in presentation of female and male patients with juvenile systemic scleroderma?

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Stanevicha, V, Sztajnbok, F, Sakamoto, AP, Alexeeva, E, Anton, J, Katsicas, M, Smith, V, Avcin, T, Cimaz, R, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Nassar, A, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Costa Reis, P, Eleftheriou, D, Harel, L, Horneff, G, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Patwardhan, A, Uziel, Y, and Helmus, N

Subjects
ddc: 610, integumentary system, 610 Medical sciences, Medicine
Abstract

Background: Juvenile systemic scleroderma (jSSc) is an orphan disease with a prevalence of 3 in 1 000 000 children. There are limited data published regarding the differences in clinical presentation of male and female patients with jSSc. The Juvenile Systemic Scleroderma Inception Cohort (JSSIC) is[for full text, please go to the a.m. URL], 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019
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31. Update from the juvenile scleroderma Inception Cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Stanevicha, V, Sztajnbok, F, Terreri, MT, Alexeeva, E, Anton, J, Katsicas, M, Smith, V, Avcin, T, Cimaz, R, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Schonenberg, D, Battagliotti, C, Berntson, L, Bica, B, Brunner, J, Costa Reis, P, Eleftheriou, D, Harel, L, Horneff, G, Kallinich, T, Lazarevic, D, Minden, K, Nielsen, S, Nuruzzaman, F, Patwardhan, A, Uziel, Y, and Helmus, N

Subjects
ddc: 610, integumentary system, 610 Medical sciences, Medicine
Abstract

Background: Juvenile systemic scleroderma (jSSc) is an orphan disease with a prevalence of 3 in 1 000 000 children. There are limited data regarding the clinical presentation of jSSc. The Juvenile Systemic Scleroderma Inception Cohort (JSSIC) is a multinational registry that prospectively collects information[for full text, please go to the a.m. URL], 47. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 33. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 29. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019
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32. Patients and physician related outcomes improve significantly over 12 months follow up in patients with juvenile systemic sclerosis. Results from the juvenile scleroderma inception cohort. www.juvenile-scleroderma.com

Author

Foeldvari, I, Klotsche, J, Terreri, MT, Katsicas, M, Stanevicha, V, Avcin, T, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Sztajnbok, F, Anton, J, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Eleftheriou, D, Harel, L, Janarthanan, M, Kallinich, T, Moll, M, Nielsen, S, Smith, V, Torok, K, and Helmus, N

Subjects
ddc: 610, integumentary system, 610 Medical sciences, Medicine, skin and connective tissue diseases
Abstract

Background: Juvenile systemic scleroderma (jSSc) is an orphan disease with an estimated prevalence of around 3 per 1 000 000 children. There are no studies which evaluated prospectively the patient related outcomes in these patients. We report the data from juvenile scleroderma inception cohort (jSSc)[for full text, please go to the a.m. URL], 46. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 32. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), Wissenschaftliche Herbsttagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2019
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33. Incidence and risk factors for gangrene in patients with systemic sclerosis from the EUSTAR cohort

Author

Mihai, Carina, Distler, Oliver, Gheorghiu, Ana Maria, Constantin, Paul I, Dobrota, Rucsandra, Jordan, Suzana, Smith, Vanessa, Hachulla, Eric, Henes, Jörg, Siegert, Elise, Vettori, Serena, Müller-Ladner, Ulf, Matucci Cerinic, Marco, Allanore, Yannick, Lepri, G, Jaeger, Vk, Walker, Ua, Iannone, F, Cacciapaglia, F, Tomčík, M, Becvar, R, Rednic, S, Petcu, A, Szabo, I, Codullo, V, Caporali, R, Montecucco, C, Carreira, P, Ioven, B, Minier, T, Czirják, L, Chizzolini, C, Allali, D, Zanatta, E, Doria, A, Gabrielli, A, Airò, P, Lazzaroni, Mg, Radić, M, Martinovic, D, Braun-Moscovici, Y, Balbir-Gurman, A, Hunzelmann, N, Caramaschi, P, Morovic-Vergles, J, Denton, C, Santamaria, V, Heitmann, S, Krasowska, D, Michalska-Jakubus, M, Seidel, M, Foeldvari, I, Helmus, N, Salvador, M, Stamenkovic, B, Stankovic, A, Ananieva, L, Herrick, A, Engelhart, M, De La Puente, C, Hoffmann-Vold, Am, Midtvedt, Ø, Launay, D, Sobanski, V, Riccieri, V, Opris-Belinski, D, Groseanu, L, Ionescu, R, Bojinca, M, Sunderkötter, C, Distler, J, Ingegnoli, F, van der Haecke, A, Ullman, S, Pozzi, Mr, Eyerich, K, Vanthuyne, M, Erler, A, Aringer, M, De Langhe, E, Baresic, M, Mayer, M, Anic, B, Yavuz, S, Granel, B, Popa, S, Agachi, S, Zenone, T, Mathieu, A, Vacca, A, Solanki, K, Veale, D, Loyo, E, Tineo, C, Gigante, A, Rosato, E, Oksel, F, Yagurcu, F, Tănăseanu, Cm, Visalli, E, Benenati, A, Foti, R, Ancuta, C, Dan, D, Adler, S, Villiger, P, Fathi, N, de la Peña Lefebvre PG, González Martín, J, Chatelus, E, Sibilia, J, Litinsky, I, Del Galdo, F, Ann Sakettkoo, L, Kerzberg, E, Bianchi, Wa, Bianchi, Bv, Castellví, I, Limonta, M, Rimar, D, Couto, M, Ribi, C, Spertini, F, Kahl, S, Hsu, V, Poindron, V, Meghit, K, Martin, T, Kolstad, K, Chung, L, Thiele, A, Schmeiser, T, Zdrojewski, Z, Riemekasten, G, Levy, Y, Cardoneanu, A, Burlui, A, Rezus, E, Pamuk, On, Talotta, R, Bongiovanni, S, Puttini, Ps., Mihai, Carina, Distler, Oliver, Gheorghiu, Ana Maria, Constantin, Paul I, Dobrota, Rucsandra, Jordan, Suzana, Smith, Vanessa, Hachulla, Eric, Henes, Jörg, Siegert, Elise, Vettori, Serena, Müller-Ladner, Ulf, Matucci Cerinic, Marco, Allanore, Yannick, Giovanna, Cuomo, Chizzolini, Carlo, Allali, Danièle, and University of Zurich

Subjects
Adult, Male, medicine.medical_specialty, Databases, Factual, systemic sclerosis, digital ulcer, 610 Medicine & health, Disease, ddc:616.07, Logistic regression, Systemic scleroderma, Cohort Studies, Rheumatology, Risk Factors, Internal medicine, Cox proportional hazards regression, medicine, Humans, Pharmacology (medical), In patient, digital ulcers, gangrene, vasculopathy, Aged, Gangrene, Scleroderma, Systemic, business.industry, Incidence (epidemiology), Incidence, 10051 Rheumatology Clinic and Institute of Physical Medicine, food and beverages, Middle Aged, medicine.disease, Cross-Sectional Studies, Cohort, Female, business, systemic sclerosi
Abstract

Objective In patients with SSc, peripheral vasculopathy can promote critical ischaemia and gangrene. The aim of this study was to investigate the prevalence, incidence and risk factors for gangrene in the EUSTAR cohort. Methods We included patients from the EUSTAR database fulfilling the ACR 1980 or the ACR/EULAR 2013 classification criteria for SSc, with at least one visit recording data on gangrene. Centres were asked for supplementary data on traditional cardiovascular risk factors. We analysed the cross-sectional relationship between gangrene and its potential risk factors by univariable and multivariable logistic regression. Longitudinal data were analysed by Cox proportional hazards regression. Results 1757 patients were analysed (age 55.9 [14.5] years, disease duration 7.9 [10.3] years, male sex 16.7%, 24.6% diffuse cutaneous subset [dcSSc]). At inclusion, 8.9% of patients had current or previous digital gangrene, 16.1% had current digital ulcers (DUs) and 42.7% had ever had DUs (current or previous). Older age, DUs ever and dcSSc were statistically significant risk factors for gangrene in the cross-sectional multivariable model. During a median follow-up of 13.1 months, 16/771 (0.9%) patients developed gangrene. All 16 patients who developed gangrene had previously had DUs and gangrene. Further risk factors for incident gangrene were the dcSSc subset and longer disease duration. Conclusion In unselected SSc patients, gangrene occurs in about 9% of SSc patients. DUs ever and, to a lesser extent, the dcSSc subset are strongly and independently associated with gangrene, while traditional cardiovascular risk factors could not be identified as risk factors.

Published
2019

34. After 24 months observation period patient reported outcomes improved significantly in the juvenile Scleroderma Inceptions Cohort

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Anton, J, Avcin, T, Cimaz, R, Kostik, M, Katsicas, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Harel, L, Kallinich, T, Minden, K, Moll, M, Patwardhan, A, Torok, K, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Anton, J, Avcin, T, Cimaz, R, Kostik, M, Katsicas, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Harel, L, Kallinich, T, Minden, K, Moll, M, Patwardhan, A, Torok, K, and Helmus, N

Published
2019

35. Do Raynaud phenomenon negative juvenile systemic scleroderma patients have a different pattern of organ involvement as Raynaud phenomenon positive patients?

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Stanevicha, V, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Sztajnbok, F, Avcin, T, Cimaz, R, Anton, J, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Costa Reis, P, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Uziel, Y, Stevens, A, Pilkington, C, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Torok, K, Stanevicha, V, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Sztajnbok, F, Avcin, T, Cimaz, R, Anton, J, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Costa Reis, P, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Uziel, Y, Stevens, A, Pilkington, C, and Helmus, N

Published
2019

36. Is there a Difference in the clinical Presentation of juvenile Systemic Scleroderma Patients according the Age of onset: Results from the juvenile Scleroderma Inception Cohort www.juvenile-scleroderma.com

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Stanevicha, V, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Cimaz, R, Kostik, M, Lehman, T, Anton, J, Sifuentes-Giraldo, WA, Sztajnbok, F, Avcin, T, Janarthanan, M, Jose Santos, M, Moll, M, Nemcova, D, Battagliotti, C, Brunner, J, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Torok, K, Uziel, J, Stevens, A, Pilkington, C, and Helmus, N

Subjects
stomatognathic diseases, ddc: 610, integumentary system, natural sciences, 610 Medical sciences, Medicine, skin and connective tissue diseases
Abstract

Background: Juvenile systemic sclerosis (jSSc) is an orphan autoimmune disease. It was rarely looked at the differences between the clinical presentations of patients at different paediatric age groups. The juvenile scleroderma inception cohort ([link:http://www.juvenile-scleroderma.com/*http://www.juvenile-scleroderma.com/])[for full text, please go to the a.m. URL], 45. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh), 31. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh), 27. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2017
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37. THU0577 Do raynaud phenomenon negative juvenile systemic scleroderma patients have a different pattern of organ involvement as raynaud phenomenon positive patients?

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Torok, K., additional, Stanevicha, V., additional, Terreri, M.T., additional, Alexeeva, E., additional, Katsikas, M., additional, Smith, V., additional, Sztajnbok, F., additional, Avcin, T., additional, Cimaz, R., additional, Anton, J., additional, Kostic, M., additional, Lehman, T., additional, Sifuentes-Giraldo, W.-A., additional, Appenzeller, S., additional, Janarthanan, M., additional, Moll, M., additional, Nemcova, D., additional, Santos, M.J., additional, Battagliotti, C., additional, Berntson, L., additional, Brunner, J., additional, Costa Reis, P., additional, Eleftheriou, D., additional, Harel, L., additional, Kallinich, T., additional, Minden, K., additional, Nielsen, S., additional, Uziel, Y., additional, Stevens, A., additional, Pilkington, C., additional, and Helmus, N., additional

Published
2018
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38. THU0578 Patients and physician related outcomes improve significantly over 12 months follow up in patients with juvenile systemic sclerosis. results from the juvenile scleroderma inception cohort. www.juvenile-scleroderma.com

Author

Foeldvari, I., primary, Klotsche, J., additional, Terreri, M.T., additional, Katsikas, M., additional, Stanevicha, V., additional, Avcin, T., additional, Cimaz, R., additional, Kostic, M., additional, Sifuentes-Giraldo, W.-A., additional, Sztajnbok, F., additional, Anton, J., additional, Nemcova, D., additional, Santos, M.J., additional, Battagliotti, C., additional, Berntson, L., additional, Brunner, J., additional, Eleftheriou, D., additional, Harel, L., additional, Janarthanan, M., additional, Kallinich, T., additional, Moll, M., additional, Nielsen, S., additional, Smith, V., additional, Torok, K., additional, Stevens, A., additional, Pilkington, C., additional, and Helmus, N., additional

Published
2018
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39. Update on the juvenile systemic Sclerosis Inception Cohort Project. Characteristics of the first 97 Patients at first Assessment. www.juvenile-scleroderma.com

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Stanevicha, V, Torok, K, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Sztajnbok, F, Avcin, T, Cimaz, R, Anton, J, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Uziel, Y, Pilkington, C, Stevens, A, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Stanevicha, V, Torok, K, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Sztajnbok, F, Avcin, T, Cimaz, R, Anton, J, Kostik, M, Lehman, T, Sifuentes-Giraldo, WA, Appenzeller, S, Janarthanan, M, Moll, M, Nemcova, D, Jose Santos, M, Battagliotti, C, Berntson, L, Brunner, J, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Uziel, Y, Pilkington, C, Stevens, A, and Helmus, N

Published
2017

41. Is there a Difference in the Presentation of male and female Patients with diffuse subtype of juvenile systemic Sclerosis? Results from the juvenile Scleroderma Inception Cohort www.juvenile-scleroderma.com

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Stanevicha, V, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Cimaz, R, Kostik, M, Lehman, T, Anton, J, Sifuentes-Giraldo, WA, Sztajnbok, F, Avcin, T, Janarthanan, M, Jose Santos, M, Moll, M, Nemcova, D, Battagliotti, C, Brunner, J, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Torok, K, Uziel, J, Stevens, A, Pilkington, C, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Stanevicha, V, Terreri, MT, Alexeeva, E, Katsicas, M, Smith, V, Cimaz, R, Kostik, M, Lehman, T, Anton, J, Sifuentes-Giraldo, WA, Sztajnbok, F, Avcin, T, Janarthanan, M, Jose Santos, M, Moll, M, Nemcova, D, Battagliotti, C, Brunner, J, Eleftheriou, D, Harel, L, Kallinich, T, Minden, K, Nielsen, S, Torok, K, Uziel, J, Stevens, A, Pilkington, C, and Helmus, N

Published
2017

42. Update on the juvenile systemic sclerosis inception cohort project (www.juvenilescleroderma.com). Characteristics of the first 74 patients at first assessment

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Stanevicha, V, Katsicas, M, Alexeeva, E, Sztajnbok, F, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Lehman, T, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Battagliotti, C, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Janarthanan, M, Harel, L, Uziel, J, Eleftheriou, D, Torok, K, and Helmus, N

Subjects
body regions, ddc: 610, organ involvement, juvenile systemic sclerosis, 610 Medical sciences, Medicine, humanities
Abstract

Background: Juvenile systemic sclerosis (jSSc) is an orphan autoimmune disease. Currently just retrospective data exist regarding evolvement of organ involvement. In the retrospective studies assessment of the organ involvement is not standardized. Our project is the first one, where prospectively and[for full text, please go to the a.m. URL], 44. Kongress der Deutschen Gesellschaft für Rheumatologie (DGRh); 30. Jahrestagung der Deutschen Gesellschaft für Orthopädische Rheumatologie (DGORh); 26. Jahrestagung der Gesellschaft für Kinder- und Jugendrheumatologie (GKJR)

Published
2016
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44. AB0957 Is there a difference in the clinical presentation of juvenile systemic scleroderma patients according the age of onset: results from the juvenile scleroderma inception cohort www.juvenile-scleroderma.com

Author

Foeldvari, I, primary, Klotsche, J, additional, Kasapçopur, O, additional, Adrovic, A, additional, Stanevicha, V, additional, Terreri, MT, additional, Alexeeva, E, additional, Katsicas, M, additional, Smith, V, additional, Cimaz, R, additional, Kostik, M, additional, Lehman, T, additional, Anton, J, additional, Sifuentes-Giraldo, W-A, additional, Sztajnbok, F, additional, Avcin, T, additional, Janarthanan, M, additional, Santos, MJ, additional, Moll, M, additional, Nemcova, D, additional, Battagliotti, C, additional, Brunner, J, additional, Eleftheriou, D, additional, Harel, L, additional, Kallinich, T, additional, Minden, K, additional, Nielsen, S, additional, Torok, K, additional, Uziel, Y, additional, Stevens, A, additional, Pilkington, C, additional, and Helmus, N, additional

Published
2017
Full Text
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45. Is there a difference in the presentation of male and female patients with juvenile systemic sclerosis? Results from the juvenile scleroderma inception cohort (www.juvenilescleroderma.com)

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Stanevicha, V, Katsicas, M, Alexeeva, E, Sztajnbok, F, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Lehman, T, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Battagliotti, C, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Janarthanan, M, Harel, L, Uziel, J, Eleftheriou, D, Torok, K, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Stanevicha, V, Katsicas, M, Alexeeva, E, Sztajnbok, F, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Lehman, T, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Battagliotti, C, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Janarthanan, M, Harel, L, Uziel, J, Eleftheriou, D, Torok, K, and Helmus, N

Published
2016

46. Is there a difference in the presentation of diffuse and limited subtype in childhood? Results from the juvenile scleroderma inception cohort (www.juvenilescleroderma.com)

Author

Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Stanevicha, V, Katsicas, M, Alexeeva, E, Sztajnbok, F, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Lehman, T, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Battagliotti, C, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Janarthanan, M, Harel, L, Uziel, J, Eleftheriou, D, Torok, K, Helmus, N, Foeldvari, I, Klotsche, J, Kasapcopur, O, Adrovic, A, Terreri, MT, Stanevicha, V, Katsicas, M, Alexeeva, E, Sztajnbok, F, Cimaz, R, Kostik, M, Sifuentes-Giraldo, WA, Lehman, T, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Battagliotti, C, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Janarthanan, M, Harel, L, Uziel, J, Eleftheriou, D, Torok, K, and Helmus, N

Published
2016

47. THU0229 Is There A Difference in The Presentation of Diffuse and Limited Subtype in Childhood? Results from The Juvenile Scleroderma Inception Cohort

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M.T., additional, Stanevicha, V., additional, Katsikas, M.M., additional, Alexeeva, E., additional, Sztajnbok, F., additional, Cimaz, R., additional, Kostik, M., additional, Sifuentes-Giraldo, W.A., additional, Lehman, T., additional, Nemcova, D., additional, Moll, M., additional, Santos, M.J., additional, Avcin, T., additional, Battagliotti, C., additional, Brunner, J., additional, Nielsen, S., additional, Kallinich, T., additional, Minden, K., additional, Janarthanan, M., additional, Harel, L., additional, Uziel, Y., additional, Eleftheriou, D., additional, Torok, K.S., additional, and Helmus, N., additional

Published
2016
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48. SAT0257 Update on The Juvenile Systemic Sclerosis Inception Cohort Project. Characteristics of The First 74 Patients at First Assessment

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M.T., additional, Stanevicha, V., additional, Katsikas, M.M., additional, Alexeeva, E., additional, Sztajnbok, F., additional, Cimaz, R., additional, Kostik, M., additional, Sifuentes-Giraldo, W.A., additional, Lehman, T., additional, Nemcova, D., additional, Moll, M., additional, Santos, M.J., additional, Avcin, T., additional, Battagliotti, C., additional, Brunner, J., additional, Nielsen, S., additional, Kallinich, T., additional, Minden, K., additional, Janarthanan, M., additional, Harel, L., additional, Uziel, Y., additional, Eleftheriou, D., additional, Torok, K.S., additional, and Helmus, N., additional

Published
2016
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49. THU0230 Is There A Difference in The Presentation of Male and Female Patients with Juvenile Systemic Sclerosis? Results from The Juvenile Scleroderma Inception Cohort

Author

Foeldvari, I., primary, Klotsche, J., additional, Kasapcopur, O., additional, Adrovic, A., additional, Terreri, M.T., additional, Stanevicha, V., additional, Katsikas, M.M., additional, Alexeeva, E., additional, Sztajnbok, F., additional, Cimaz, R., additional, Kostik, M., additional, Sifuentes-Giraldo, W.A., additional, Lehman, T., additional, Nemcova, D., additional, Moll, M., additional, Santos, M.J., additional, Avcin, T., additional, Battagliotti, C., additional, Brunner, J., additional, Nielsen, S., additional, Kallinich, T., additional, Minden, K., additional, Janarthanan, M., additional, Harel, L., additional, Uziel, Y., additional, Eleftheriou, D., additional, Torok, K.S., additional, and Helmus, N., additional

Published
2016
Full Text
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50. Update on the juvenile systemic sclerosis inception cohort WWW.JUVENILE-SCLERODERMA.COM

Author

Foeldvari, I, Katsicas, M, Terreri, MT, Cimaz, R, Kostik, M, Sztajnbok, F, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Müller, J, Janarthanan, M, Uziel, Y, Sifuentes-Giraldo, WA, Eleftheriou, D, Torok, K, Helmus, N, Foeldvari, I, Katsicas, M, Terreri, MT, Cimaz, R, Kostik, M, Sztajnbok, F, Nemcova, D, Moll, M, Jose Santos, M, Avcin, T, Brunner, J, Nielsen, S, Kallinich, T, Minden, K, Müller, J, Janarthanan, M, Uziel, Y, Sifuentes-Giraldo, WA, Eleftheriou, D, Torok, K, and Helmus, N

Published
2015

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