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ABSTRACT. The purpose of this study was to examine replacement rice bran (RB) with the mixture of Aloe vera flour (AVF) + sunflower seed flour (SFS) within the fermented feed of which with the addition of other feed ingredients used to replace 25% of the commercial diet on carcass yields, internal organs, and abdominal fat of broilers. The study was conducted at the Field Laboratory of Animal Husbandry, the Faculty of Agriculture, Syiah Kuala University. The study used 100 chicks strain Cobb applied in a Completely Randomized Design with sub-samplings consisting of 5 treatments, 4 replicates, and 2 sub-samples. The treatments were 100% CP511 (control+) and 4 FF-based diets: FF3% RB (control-), FF3% AVF, FF3% SFS, and FF3% AVF + 3% SFS. The results of this study showed that replacing rice bran with AVS and SFS either exclusively or in combination in equal amount 3% each did not significantly affect (P0.05) the percentages of the carcass, cut-ups, internal organs, and abdominal fat of broilers. In conclusion, either Aloe vera or sunflower seed flour could be incorporated 3% each in a single source or in combination to replace rice bran within the fermented feed. without adverse effects on carcass yields and internal organs as well as abdominal fats of broilers. (Pengaruh penggantian dedak dengan tepung lidah buaya dan biji bunga matahari dalam bahan pakan fermentasi terhadap berat karkas, organ dalam dan lemak abdomen ayam broiler) ABSTRAK. Penelitian ini bertujuan untuk mengamati pengaruh penggantian dedak padi (DP) dengan campuran tepung lidah buaya (TLB) dan biji bunga matahari (TBM) dalam bahan pakan fermentasi yang tersusun dan beberapa bahan pakan lain yang digunakan untuk menggantikan 25% ransum komersil terhadap berat dan persentase karkas, organ dalam, dan lemak abdomen ayam broiler. Penelitian dilakukan di Laboratorium Lapangan Peternakan (LLP), Fakultas Pertanian, Universitas Syiah Kuala. Penelitian menggunakan 100 ekor anak ayam broiler strain Cobb. Rancangan yang digunakan adalah Rancangan Acak Lengkap sub sampel terdiri dari 5 perlakuan, 4 ulangan, dan 2 sub sampel. Hasil penelitian memperlihatkan bahwa penggunaan TLB yang dicampur dengan TBM masing-masing sebanyak 3% tidak berpengaruh nyata (P0,05) terhadap berat dan persentase karkas, organ dalam, dan lemak abdomen ayam broiler. Kesimpulannya, TLB dan TBM masing-masing 3% ataupun campurannya 6% dapat digunakan untuk menggantikan dedak padi dalam bahan pakan fermentasi.

Abstrak Pencegahan dampak cekaman panas pada ayam broiler dapat dilakukan dengan pemberian ekstrak tanaman yang juga berguna dalam pengembangan obat-obat tradisional sebagai alternatif pengurangan penggunaan bahan-bahan kimiawi. Tujuan penelitian ini adalah untuk mengevaluasi performan ayam broiler yang diberikan ekstrak daun jaloh melalui air minum. Penelitian dilakukan di Laboratorium Lapangan Peternakan (LLP), Jurusan Peternakan, Fakultas Pertanian, Universitas Syiah Kuala. Sebanyak 80 ekor anak ayam broiler strain MB 202 produksi PT Japfa, Medan digunakan dalam penelitian ini. Perlakuan adalah suplementasi ekstrak daun jaloh melalui air minum pada dosis 0, 500, 1000, and 1500 ml/l air. Rancangan yang digunakan adalah Rancangan Acak Blok terdiri 4 perlakuan dan 4 blok. Tiap blok merupakan eksperimental unit yang masing-masing ditempati 5 ekor ayam. Hasil penelitian memperlihatkan walaupun secara statistik tidak berbeda nyata (P>0,05), suplementasi ekstrak daun jaloh di dalam air minum cenderung meningkatkan performan ayam broiler. Berat badan akhir, konsumsi ransum, dan konsumsi air minum meningkat sedangkan FCR menurun. Hasil penelitian disimpulkan bahwa pemberian ekstrak daun jaloh melalui air minum dapat menurunkan cekaman panas dan kematian ayam broiler dengan penggunaan terbaik pada pengenceran 1000 ml /l water air. Kata kunci: Jaloh; leaf, ekstrak, broiler, performan Abstract Prevent heat stress in broilers has been optionally created by using plants as starting points for drug development, specifically those used in traditional medicine. The objective of this study was to evaluate the performances of broiler chickens raised by offering jaloh leaf extract (JLE) through drinking water. The research has been conducted at the Field Laboratory of Animal Husbandry, Animal Husbandry Department, Syiah Kuala University. As many as 80 broiler chicks strain MB 202 produced by PT Japfa, Medan were used in this study. The treatment was supplementation JLE within drinking water at a dose of 0, 500, 1000, and 1500 ml/l of water, respectively. The research was performed into a Block Randomized Design (RBD), consisting of 4 treatments and 4 blocks. Each block was an experimental unit, each of which was placed by 5 chickens. The results of study indicated that although statistically no significant differences were detected (P>0.05) supplementation of JLE through drinking water had tendency to improve the performances of broilers. Final body weight, body weight gain, feed intake. and drinking water intake increased and FCR decreased. It was concluded that giving JLE through drinking water could minimize heat stress and reduce the mortality of broilers with the best provision of JLE at the level of 1000 ml /l water. Key words: Jaloh; leaf, extract, broiler, performances

The residue originated from antibiotics and hormones had been thought to carry out adverse effects for the human who consume meat processed from the broilers treated by antibiotic feed additive. For this reason, using an alternative additive such as probiotic might produce healthier meat. The objective of the recent study was to evaluate administering different levels of probiotic yakult + tape yeast (YTy) into the mixing of rice bran + corn bran (RCB) to replace 30% of the commercial diet to carcass yield and abdominal fat of broilers. As many as 100 broiler chicks, Cobb strain, were reared up to 5 weeks in this study. The study was designed into a Completely Randomized Design with subsampling consisted of 5 treatments, 4 replications, and 2 sub samples. Broiler commercial diet with the market code of CP 511 Hi-provite manufactured by PT Charoen Pokphand was used for a positive control diet (P0+). The RCB feeds were mixed with 0, 10, 20, and 30 ml/kg of probiotic YTy then being used to replace 30% of the commercial diet to build experimental diets P0-, P1, P2, and P3, respectively. The results of the recent study indicated that administering 10‒30 ml/kg of probiotic YTy highly significantly (P

Penelitian bertujuan untuk mengkaji potensi penggunaan tepung daun Indigofera sp terfermentasi dalam campuran ransum komersial terhadap performan ayam lokal pedaging unggul. Materi penelitian yang digunakan adalah ayam lokal pedaging unggul (ALPU) umur sehari (DOC) sebanyak 100 ekor dan dipelihara sampai umur 70 hari. Metode penelitian dilakukan secara eksperimental menggunakan rancangan acak lengkap (RAL) dengan 4 perlakuan ransum dan 5 ulangan. Ransum perlakuan yang digunakan adalah: R1 (100% ransum komersial/kontrol), R2 (95% ransum komersial + 5% tepung daun Indigofera sp terfermentasi), R3 (90% ransum komersial + 10% tepung daun Indigofera sp terfermentasi), dan R4 (85% ransum komersial + 15% tepung daun Indigofera sp terfermentasi). Variabel yang diamati meliputi: konsumsi ransum, pertambahan bobot badan, konversi ransum, efisiensi ransum, bobot badan akhir, bobot karkas, persentase karkas dan harga ransum. Data yang diperoleh dianalisis dengan analisys of variance (ANOVA). Hasil penelitian menunjukkan bahwa penggunaan tepung daun Indigofera sp terfermentasi dalam campuran ransum komersial tidak berpengaruh nyata terhadap performan ayam lokal pedaging unggul (konsumsi ransum, pertambahan bobot badan, konversi ransum, efisiensi ransum, bobot badan akhir, bobot karkas dan persentase karkas). Disimpulkan bahwa penggunaan tepung daun Indigofera sp terfermentasi tidak memberi efek negatif dan dapat digunakan sampai 15% dalam campuran ransum komersial tanpa memengaruhi performan ALPU. Kata kunci: ALPU, performan, Indigofera sp, fermentasi

The purpose of this service activity was the implementation of socialization and training on environmental modification and feed management to overcome heat stress in goat cattle at the dairy goat farm of the Lamlumpu Village Community, Peukan Bada Sub-District, Aceh Besar District. The method of implementing this activity are in the form of socialization, counseling, and training on a scheduled basis with material on dairy goat farming patterns in the tropics, modifying the environment to create a microclimate condition that is in accordance with the comfort zone for dairy cattle, and introduction of feed ingredients that have the potential to overcome heat stress. in the livestock. The results of this community service activity indicate that the implementation of environmental and feed modifications to overcome heat stress in goat cattle shows an increase in livestock production in the form of increased milk production, more comfortable environmental conditions, and a decrease in heat stress threshold in the livestock. In conclusion, environmental and feed modifications for dairy goats in Lamplumpu Village can improve microclimate conditions so that they are more comfortable and can cope with heat stress.

ABSTRAK. Recently, exploring unconventional feedstuffs were not merely interested at the point of lower cost, but also natural sources and supporting bird health have been noticing on the critical assessments by poultry nutritionists to serve well broiler meat. This study aimed to examine the effect of including fermented moringa leaf meal (fMOL) + yellow corn (yC) to substitute fractionally commercial diet (CD) on the performances and Income over Feed Cost (IOFC) of the broiler chickens. The study was done in the Field Laboratory of Animal Husbandry, Animal Husbandry Department, Syiah Kuala University from August 4 until September 15, 2020. The study used 100 broiler chicks strain CP 707, unsex. This study was set up into Block Randomized Design (BRD) consisting of 4 treatments and 5 blocks. The treatments were MC0 = 100% CD, MC1= 95% CD + 2,5% fMOL + 2,5% yC, MC2= 90% CDR + 5% fMOL + 5% yC, and MC3= 85% CD + 7,5% fMOL + 7,5% yC. The results of studies showed that including fMOL + yC to substitute partly commercial diet significantly (P0.05) reduced final body weight (FBW) and increased feed conversion ratio (FCR) of the broilers. Feed consumption statistically was not significantly affected but tended to reduce. Using fMOL + yC reduced feed cost but revenue and IOFC also declined. (Pengaruh penggunaan campuran daun kelor dan jagung terhadap performan dan IOFC ayam broiler) ABSTRACT. Tujuan penelitian ini adalah untuk melihat pengaruh penggunaan tepung daun kelor fermentasi (TKF) ditambah dengan jagung kuning (JK) sebagai pengganti sebagian ransum komersil (RK) terhadap performan ayam broiler. Penelitian ini dilakukan di Laboratorium Lapangan Peternakan, Fakultas Pertanian Universitas Syiah Kuala, Banda Aceh. Materi yang digunakan adalah 100 ekor DOC ayam broiler strain CP 707. Ransum perlakuan adalah MC0= RK 100%, MC1= 95% RK + 2,5% TKF + 2,5% JK, MC2= 90% RK + 5% TKF + 5% JK, dan MC3= 85% RK + 7,5% TKF + 7,5% JK. Rancangan yang digunakan adalah Rancangan Acak Kelompok (RAK) terdiri dari 4 perlakuan dan 5 kelompok. Pengelompokan didasarkan pada berat badan ayam pada awal minggu ketiga. Parameter yang diamati meliputi berat badan akhir, konsumsi dan konversi ransum, dan Income Over Feed and Cost (IOFC), Hasil penelitian memperlihatkan bahwa penggunaan TKF + JK sebagai substitusi sebagian ransum komersil nyata (P0,05) menurunkan berat badan akhir dan meningkatkan konversi ransum. Konsumsi ransum tidak nyata berpengaruh, namun cenderung menurun. Pengunaan daun kelor menurunkan biaya ransum, dan IOFC.

ABSTRACT. The objective of this research is to learn the effect of shell color and storage length on egg quality. The research was held at the Animal Nutrion Laboratory Departement of Agriculture, Syiah Kuala University. The treatments were shell color 30 SC (dark brown): 30-40 SC (white) with 10 replication and store in 27 0C and 10 0C for 35 days. The observation was taken every 7 days. Parameters measured were foam ability and Haugh Unit by group random sampling design with factorial pattern. The result shows that temperature and storage length significantly effect foam ability but not in haugh unit. Storage temperature and storage temperature at 10 0C show that foam ability is better with the average of 422.31 cm3. Compared to 27 0C with the average of 394.04 cm3. On the other hand shell color has no effect both on foam ability and Haugh Unit. In general, shell color, storage length and storage temperature have no effect on egg quality.

ABSTRACT. A study on performance of crossed local cock with Kedu hen on production phase given diet with different level of protein have been conducted at experimental farm of Syiah Kuala University. The objective of the research was to study the production performance of local chiken and crossed local cock with Kedu given different level of protein. There were 24 local chiken and 24 crossed local cock and Kedu hen used in trial. The study was designed in Completely Randomized Design (CRD) with factorial pattern 2 x 3 and 4 replications. There were 2 chicks in each replications. First factor was breed of chicken (A); there were local breed of chiken (A1) and crossed breed of chicken (A2). The second factors were the level of protein in the diet e.g. 16% (R1), 18%(R2), and 20%(R3). Parameters studied were feed consumption, hen day production egg weight, feed conversion and egg indext. The data were analyzed by and analysis of variance and as a significant effect was detected, the analysis was breed and crossed breed. However, there were no significant effect on feed consumption, hen day production, egg weight, feed conversion and egg index. Generally, performance of local breed hen which was feed on 20% protein on the diet.

(Active component analysis of fermented milk flavor by gas chromatography) ABSTRACT. Fermented milk is milk processed product that to be one source of nutritious food for humans. The action of food component such as flavor is accepted, sense of taste and smell generated complex assessment of food flavors in the mouth. The flavor components of fermented milk together and interact with each other when consumed and cause the perception of taste between like or dislike. This is an important factor in developing diversification of fermented milk product so as to attract customers other than in terms of aspects of nutrition and health. Flavor is one of the most important criteria in the acceptance of a food ingredient. During processing and storage flavor change easily. This study used gas chromatography to detect the formation of the active component of the flavor of fermented milk. The purpose of this study was to determine the active components in fermented milk which is the formation of flavor. This research was conducted in the Laboratory of Animal Feed Laboratory of the Faculty of Agriculture and Food Chemistry Unsyiah and PAU Food and Nutrition IPB Bogor. This study uses a Likens - Nickerson distillation stage concentrated with Vigreux column and identified by Gas Chromatography Mass Spectrometer. Gas chromatography has identified that the class of acids, alcohols, esters and alkanes group forming an active component in the flavor of fermented milk although relatively varied. In yoghurt, acid found in relatively high amount of alcohol is more varied in its kind. Yogurt with single culture L.bulgaricus has more ketones and aldehydes components. Volatile components were detected mostly in kefir acids, alcohols, esters and alkane derivatives. The curd is dominated by acidic components in addition to alcohol and aldehyde.

Declined cognitive function is commonly complained during the menopausal transition and continues afterward. Combining different exercises potentially leads to greater improvements in cognitive function, however, evidence of the benefits that accrue with multicomponent exercise training, specifically for postmenopausal women is limited. Therefore, this study aimed to investigate the effects of short-term multicomponent exercise training programs on executive function in postmenopausal women. Thirty women (59.8 ± 5.2 years), who were at least 12 months post menopause were allocated into a control (CON) group and an exercise (EX) training group. The EX group underwent a 2-week (five times/week) multicomponent exercise program comprising aerobic, strength, flexibility, and balance exercises for 40-60 min. Executive function was assessed by using the Stroop test and global cognitive function was assessed using the Mini-Mental State Examination (MMSE) at baseline (pre) and after 2 weeks (post) of exercise. The EX group showed improved performance in the Stroop test, with faster inhibition reaction time (ES (g) = 0.76; p = 0.039) and fewer errors across all tasks (color naming: g = 0.8, p = 0.032; word reading: g = 0.88, p = 0.019; inhibition: g = 0.99, p = 0.009; switching: g = 0.93, p = 0.012) following exercise intervention. Additionally, statistical analysis of the MMSE score showed a significant improvement (g = 1.27; p = 0.001). In conclusion, our findings suggest that a short-term multicomponent exercise program improves selective tasks of executive function in postmenopausal women along with global cognitive function. Trial registration ISRCTN13086152., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Ramadhana et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Purpose: Hybrid learning has been chosen as an alternative method in the conduction of clinical skill lectures during coronavirus disease 2019 (COVID-19) pandemic since students need to learn skills applied in emergency situations. This study aims to analyze students' attitudes between hybrid and online learning methods., Methods: A non-randomized study was conducted between hybrid group (HG) and online group (OG) on three courses (intravenous [IV]-line insertion, nasogastric tube [NGT] insertion, and neonatal resuscitation). We developed a preformed validated questionnaire to assess students' attitudes in five domains (willingness, understanding, capacity, self-efficacy, and intended behavior). The questionnaire was applied at the pre- and post-intervention., Results: A total of 100 participants were included (n=49 in HG, n=51 in OG). Post-course attitudes were significantly higher in online (IV-line, p=0.000; NGT, p=0.000; resuscitation, p=0.000) and hybrid (IV-line, p=0.000; NGT, p=0.000; resuscitation, p=0.000) groups compared to their pre-course. There were no significant differences in post-course attitude between groups (IV-line, p=0.072; NGT, p=0.163; resuscitation, p=0.146). Normalized-gain scores of all subjects were higher in HG (IV-line, p=0.012; NGT, p=0.085; resuscitation, p=0.033)., Conclusion: In conclusion, hybrid learning could be considered as a better alternative in clinical skill lectures to maximize students' attitudes, especially during COVID-19 pandemic.

Purpose of Review: This retrospective study investigated factors that influence the occurrence of decreased systolic and diastolic blood pressure including sociodemographic and economic factors, hypertension duration, cigarette consumption, alcohol consumption, duration of smoking, type of cigarettes, exercise, salt consumption, sleeping pills consumption, insomnia, and diabetes. These factors were applied to predict the reality of systolic and diastolic decrease using the machine learning algorithm Naïve Bayes, artificial neural network, logistic regression, and decision tree., Recent Findings: The increase in blood pressure, both systolic and diastolic, is very harmful to the health because uncontrolled high systolic and diastolic blood pressure can cause various diseases such as congestive heart failure, kidney failure, and cardiovascular disease. There have been many studies examining the factors that influence the occurrence of hypertension, but few studies have used machine learning to predict hypertension. The machine learning models performed well and can be used for predicting whether a person with hypertension with certain characteristics will experience a decrease in their systolic or diastolic blood pressure after treatment with antihypertensive drugs., (© 2023. The Author(s).)

Health professionals (HPs) can play an important role in influencing the smoking behavior of their patients and the implementation of smoke-free workplace policies. In some countries physicians and dentists may not have a no-smoking policy in place. Breathing in other people's tobacco smoke (second-hand smokers) increase the risk of smoking related diseases. Environmental Tobacco smoke ETS causes a similar range of diseases to active smoking, including various cancers, heart disease, stroke, and respiratory diseases. Little is known about the smoking-related attitudes and clinical practices of HPs in Indonesia. Evidence suggests that high smoking rates remain among male HPs; however, the risk perceptions and attitudes to smoking among Indonesian HPs have not been investigated using prediction model artificial neural networks. For this reason, we developed and validated an artificial neural network (ANN) to identify HPs with smoking behavior. The study population consisted of 240 HPs, including 108 (45%) physicians, and 132 (55%) dentists, with more female (n=159) than male participants (n=81) for both professions. Participants were randomly divided into two sets, the training (192) and test (48) sets. The input variables included gender, profession (doctor or dentist), knowledge regarding smoking-related diseases and awareness of smoking provided to their patients, smoke-free policy in place at their workplace, and smoking status. ANN was constructed with data from the training and selection sets and validated in the test set. The performance of ANN was simultaneously evaluated by discrimination and calibration. After the training, we completed the process using the test dataset with a multilayer perceptron network, determined by 36 input variables. Our results suggested that our final ANN concurrently had good precision (89%), accuracy (81%), sensitivity (85%), and area under the curve (AUC; 70%). ANN can be used as a promising tool for the prediction of smoking status based on health risk perceptions of HPs in Indonesia.

Objectives: Positive energy homeostasis due to overnutrition and a sedentary lifestyle triggers obesity. Obesity has a close relationship with elevated levels of betatrophin and may increase the risk of developing metabolic syndrome. Therefore, lifestyle modification through a nonpharmacological approach based on physical exercise is the right strategy in lowering betatrophin levels. This study aimed to analyze the effect of moderate-intensity interval and continuous exercises on decreased betatrophin levels and the association between betatrophin levels and obesity markers in women., Methods: A total of 30 women aged 20-24 years old were randomly divided into three groups. Measurement of betatrophin levels using Enzyme-Linked Immunosorbent Assay (ELISA). Data analysis techniques used were one-way ANOVA and parametric linear correlation., Results: The results showed that the average levels of betatrophin pre-exercise were 200.40 ± 11.03 pg/mL at CON, 203.07 ± 42.48 pg/mL at MIE, 196.62 ± 21.29 pg/mL at MCE, and p=0.978. Average levels of betatrophin post-exercise were 226.65 ± 18.96 pg/mL at CON, 109.31 ± 11.23 pg/mL at MIE, 52.38 ± 8.18 pg/mL at MCE, and p=0.000. Pre-exercise betatrophin levels were positively correlated with age, BMI, FM, WHR, FBG, and PBF (p≤0.001)., Conclusions: Our study showed that betatrophin levels are decreased by 10 min post-MIE and post-MCE. However, moderate-intensity continuous exercise is more effective in lowering betatrophin levels than moderate-intensity interval exercise. In addition, pre-exercise betatrophin levels also have a positive correlation with obesity markers., (© 2022 Walter de Gruyter GmbH, Berlin/Boston.)

The comparative efficacy of various approaches of digital cognitive behavioral therapy for insomnia (CBTi) is still unclear. This network meta-analysis explored the comparative efficacy of digital CBTi approaches in adults with insomnia. Four electronic databases were searched from inception to June 27, 2020. Primary outcomes were self-reported total sleep time (TST), sleep onset latency (SOL), wake after sleep onset (WASO), sleep efficiency (SE), and insomnia symptoms; these were measured using sleep diaries or valid questionnaires. A random-effects network meta-analysis in a frequentist framework was used. Fifty-four randomized controlled trials comprising 11,815 participants were included. Compared with usual care, web-based CBTi with a therapist demonstrated significantly longer TST (mean difference [MD]: 23.19 min, 95% confidence interval [CI]: 18.98-27.39 min), shorter SOL (MD: -18.76 min, 95% CI -24.20 to -13.31 min), lower WASO (MD: -31.40 min, 95% CI: -36.26 to -26.55 min), and greater SE (MD: 10.37%, 95% CI: 8.08%-12.65%). The surface under the cumulative ranking curve indicates that web-based CBTi with therapists is most likely to be ranked the highest among all treatments, and thus, this network meta-analysis suggests that such a treatment is the optimal intervention for improving sleep duration and SE as well as the reductions in SOL and WASO. PROSPERO REGISTRATION NUMBER: CRD42020171134., Competing Interests: Conflicts of interest The authors have no conflicts of interest to declare., (Copyright © 2021 Elsevier Ltd. All rights reserved.)

Objective: Exercise is a risk factor for infertility in women. However, research on the effects of different intensities of exercise on folliculogenesis has not yielded clear results. This study was conducted to analyze the effects of differences in the intensity of exercise on folliculogenesis in mice., Methods: Nineteen female BALB/c mice (age, 3-4 months; weight, 13-25 g) were randomly divided into four groups: control, mild exercise, moderate exercise, and high-intensity exercise. The mice in the exercise groups engaged in swimming, with additional loads of 3%, 6%, or 9% of body weight, respectively. There were five swimming sessions per week for 4 weeks, with a gradually increasing duration every week. At the end of the treatment, ovarian extraction was carried out and hematoxylin and eosin staining was performed to identify folliculogenesis., Results: There were significant differences in the number of total follicles between the control and moderate-exercise groups (p=0.036) and between the mild- and moderate-exercise groups (p=0.005). The mean number of primary follicles was higher in the moderate-exercise group than in the mild-exercise group (p=0.006). The mean number of secondary, tertiary, and Graafian follicles did not differ significantly among groups (p≥0.05). However, the number of total follicles and follicles in each phase tended to increase after exercise, especially moderate-intensity exercise., Conclusion: Exercise of different intensities affected the total number of follicles and primary follicles. The number of follicles of each phase tended to increase after exercise. Moderate-intensity exercise had better effects than other intensities of exercise.

Background: Distinguishing between Acute Coronary Syndrom (ACS) and SCAD (Stable Coronary Artery Disease) requires advanced laboratory instrument and electrocardiogram. However, their availabilities in primary care settings in developing countries are limited. Hematologic changes usually occur in the ACS patient and might be valuable to distinguish ACS from SCAD., Aim: This study compares the hematologic indices between ACS and SCAD patients and analyses its predictive value for ACS., Material and Methods: A total of 191 patients (79 ACS and 112 SCAD) were enrolled in this study based on the inclusion criteria. Patient's characteristic, hematologic indices on admission, and the final diagnosis were obtained from medical records. Statistical analyses were done using SPSS 23.0., Results: In this research MCHC value (33.40 vs. 32.80 g/dL; p < 0.05); WBC (11.16 vs. 7.40 x109/L; p < 0.001); NLR (6.29 vs. 2.18; p < 0.001); and PLR (173.88 vs 122.46; p < 0.001) were significantly higher in ACS compared to SCAD patients. While MPV (6.40 vs. 10.00 fL; p < 0.001) was significantly lower in ACS patients. ROC curve analysis showed MPV had the highest AUC (95%) for ACS diagnosis with an optimum cut-off point at ≤ 8.35 fL (sensitivity 93.6% and specificity 97.3%)., Conclusion: There was a significant difference between hematologic indices between ACS and SCAD patients. MPV is the best indices to distinguish ACS., (Copyright: © 2019 Kevin Luke, Bambang Purwanto, Lilik Herawati, Makhyan Jibril Al-Farabi, Yudi Her Oktaviono.)

Background Several studies have shown that there is a significant relationship between teenagers and parental smoking behavior. This study was to empower parent (smokers and non-smokers) to raise parents' concern, to describe teenagers' knowledge about smoking and its dangers, to reduce the status of teenage smoking behavior, and to decrease the number of cigarettes smoked/day. Methods This was a quasi-experimental study, with a pretest-posttest group design. The respondents were 649 students from the 8th grade in junior high schools from three provinces in Indonesia divided into two intervention groups and one control group. The dependent variable was the implementation of parent educators (smokers and non-smokers) who were trained about smoking and its dangers. Data were analyzed by analysis of variance (ANOVA) and the Kruskal-Wallis test, with a significant level of 0.05. Results The results showed that the smoking parent educator model increased the frequency of parent concern significantly and improved knowledge about the dangers of smoking insignificantly; whereas the non-smoker parent educator model decreased the number of respondents' frequent smoking status insignificantly and reduced the number of cigarettes smoked /day by the frequent smoker respondents significantly. Conclusion The parent educator model can be used for preventing teenage smoking behavior.

Smoking behavior is a threat for Indonesian teenagers, including in the city of Jayapura, Papua province. The purpose of this study was to access Jayapura teenagers smoking behavior and knowledge including parents and other family members. The study was conducted on 78 respondents (grade 7, aged 11-14 years old), using cluster random sampling for selecting the public and private junior high school in Jayapura. The data collected was smoking behavior of respondents, parents and other family members (using self-reported questionnaire), and respondents' knowledge about the dangers of smoking (using tests with Cronbach's alpha 0.701). Data were analyzed descriptively and analytically using Chi-square, 95 % level of significant. The results showed 29.3 % of teenagers, 69.23 % of parents and 25.6 % of other family members were smokers, their knowledge was low (an average score of 60.81 out of 100), there was no significant statistical relationship between knowledge and smoking behavior among respondents (p = 0.079), and there is no significant relationship between teenagers behavior with the behavior of the parents (p = 0.609) and other family members (p = 0.578), 87 % of teenagers became smokers because there were individuals who smoke at home.

Purpose: Hepatitis C (HCV) infections are prevalent in custodial settings worldwide, yet provision of antiviral therapies is uncommon. Approximately 30,000 prisoners are held in Australian prisons at any one time, with more than 30 per cent testing positive for HCV antibodies. Prisoners have been identified in the National Hepatitis C Strategy as a priority population for assessment and treatment. The purpose of this paper is to examine the rates of HCV testing and treatment, as well as barriers and opportunities for development of infrastructure for enhanced services., Design/methodology/approach: Interviews were conducted with 55 stakeholders from the correctional sector in each state and territory in Australia in two stages: service directors to gather quantitative data regarding rates of testing and treatment; and other stakeholders for qualitative information regarding barriers and opportunities., Findings: Of more than 50,000 individuals put in in custody in Australian prisons in 2013, approximately 8,000 individuals were HCV antibody positive, yet only 313 prisoners received antiviral treatment. The barriers identified to assessment and treatment at the prisoner-level included: fear of side effects and the stigma of being identified to custodial authorities as HCV infected and a likely injecting drug user. Prisoners who came forward may be considered unsuitable for treatment because of prevalent mental health problems and ongoing injecting drug use. Provision of specialist hepatitis nurses and consultants were the most frequently recommended approaches to how prison hepatitis services could be improved., Originality/value: Many personal and systems-level barriers relevant to the delivery of HCV treatment services in the custodial setting were identified. Ready access to skilled nursing and medical staff as well as direct acting antiviral therapies will allow the prison-sector to make a major contribution to control of the growing burden of HCV disease.

We aimed to investigate whether treatment with levodopa/carbidopa/entacapone when compared with levodopa/carbidopa improves quality of life in Parkinson's disease (PD) patients with no or minimal, nondisabling motor fluctuations. This is a multicenter, randomized, double-blind study. One hundred eighty-four patients on 3 to 4 equal doses of 100/25 to 200/50 mg levodopa/carbidopa or levodopa/benserazide, 0 to 3 hours of nondisabling OFF time over a 48 hour period and no dyskinesia were randomized to levodopa/carbidopa/entacapone or levodopa/carbidopa treatment for 12 weeks. The primary outcome measure was quality of life as assessed by the PDQ-8. Secondary outcome measures were the UPDRS parts I-IV, and the Wearing Off Card. Treatment with levodopa/carbidopa/entacapone resulted in significantly greater improvements in PDQ-8 scores compared to treatment with levodopa/carbidopa (mean difference 1.4 points, P = 0.021). Statistically significant improvements were seen predominantly in nonmotor domains (depression, personal relationships, communication, stigma, all P < 0.05; dressing P = 0.056). Patients who were randomly assigned to levodopa/carbidopa/entacapone also showed significantly greater improvement in UPDRS part II scores (P = 0.032) with UPDRS part III scores showing borderline significance. Differences in UPDRS parts I and IV and Wearing Off Card scores were not significant. Treatment with levodopa/carbidopa/entacapone results in improved quality of life compared with levodopa/carbidopa in PD patients with mild or minimal, nondisabling motor fluctuations.