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5 results on '"Hernández-Ramírez, Raúl Ulise"'

1. Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium

Author

Martimianaki, Georgia, Alicandro, Gianfranco, Pelucchi, Claudio, Bonzi, Rossella, Rota, Matteo, Hu, Jinfu, Johnson, Kenneth C, Rabkin, Charles S, Liao, Linda M, Sinha, Rashmi, Zhang, Zuo-Feng, Dalmartello, Michela, Lunet, Nuno Miguel De Sousa, Morais, Samantha, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Tsugane, Shoichiro, Hidaka, Akihisa, Curado, Maria Paula, Dias-Neto, Emmanuel, Zaridze, David, Maximovitch, Dmitry, Vioque, Jesu, Garcia de la Hera, Manoli, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulise, Hamada, Gerson Shigueaki, Ward, Mary H, Mu, Lina, Malekzadeh, Reza, Pourfarzi, Farhad, Trichopoulou, Antonia, Karakatsani, Anna, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Boccia, Stefania, Boffetta, Paolo, Camargo, M Constanza, Negri, Eva, La Vecchia, Carlo, Lunet, Nuno, Boccia, Stefania (ORCID:0000-0002-1864-749X), Martimianaki, Georgia, Alicandro, Gianfranco, Pelucchi, Claudio, Bonzi, Rossella, Rota, Matteo, Hu, Jinfu, Johnson, Kenneth C, Rabkin, Charles S, Liao, Linda M, Sinha, Rashmi, Zhang, Zuo-Feng, Dalmartello, Michela, Lunet, Nuno Miguel De Sousa, Morais, Samantha, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Tsugane, Shoichiro, Hidaka, Akihisa, Curado, Maria Paula, Dias-Neto, Emmanuel, Zaridze, David, Maximovitch, Dmitry, Vioque, Jesu, Garcia de la Hera, Manoli, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulise, Hamada, Gerson Shigueaki, Ward, Mary H, Mu, Lina, Malekzadeh, Reza, Pourfarzi, Farhad, Trichopoulou, Antonia, Karakatsani, Anna, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Boccia, Stefania, Boffetta, Paolo, Camargo, M Constanza, Negri, Eva, La Vecchia, Carlo, Lunet, Nuno, and Boccia, Stefania (ORCID:0000-0002-1864-749X)

Abstract

Background Evidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium. Methods A total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea drinkers were estimated by one and two-stage modelling analyses, including terms for sex, age and the main recognised risk factors for gastric cancer. Results Compared to non-regular drinkers, the estimated adjusted pooled OR for regular tea drinkers was 0.91 (95% CI: 0.85-0.97). When the amount of tea consumed was considered, the OR for consumption of 1-2 cups/day was 1.01 (95% CI: 0.94-1.09) and for >3 cups/day was 0.91 (95% CI: 0.80-1.03). Stronger inverse associations emerged among regular drinkers in China and Japan (OR: 0.67, 95% CI: 0.49-0.91) where green tea is consumed, in subjects with H. pylori infection (OR: 0.68, 95% CI: 0.58-0.80), and for gastric cardia cancer (OR: 0.64, 95% CI: 0.49-0.84). Conclusion Our results indicate a weak inverse association between tea consumption and gastric cancer.

Published
2022

2. Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium

Author

Martimianaki, Georgia, Bertuccio, Paola, Alicandro, Gianfranco, Pelucchi, Claudio, Bravi, Francesca, Carioli, Greta, Bonzi, Rossella, Rabkin, Charles S, Liao, Linda M, Sinha, Rashmi, Johnson, Ken, Hu, Jinfu, Palli, Domenico, Ferraroni, Monica, Lunet, Nuno Miguel De Sousa, Morais, Samantha, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson Shigueaki, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulise, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Martin, Vicente, Ward, Mary H, Vioque, Jesu, Garcia de la Hera, Manoli, Zhang, Zuo-Feng, Kurtz, Robert C, Lagiou, Pagona, Lagiou, Areti, Trichopoulou, Antonia, Karakatsani, Anna, Malekzadeh, Reza, Camargo, M Costanza, Curado, Maria Paula, Boccia, Stefania, Boffetta, Paolo, Negri, Eva, La Vecchia, Carlo, Lunet, Nuno, Boccia, Stefania (ORCID:0000-0002-1864-749X), Martimianaki, Georgia, Bertuccio, Paola, Alicandro, Gianfranco, Pelucchi, Claudio, Bravi, Francesca, Carioli, Greta, Bonzi, Rossella, Rabkin, Charles S, Liao, Linda M, Sinha, Rashmi, Johnson, Ken, Hu, Jinfu, Palli, Domenico, Ferraroni, Monica, Lunet, Nuno Miguel De Sousa, Morais, Samantha, Tsugane, Shoichiro, Hidaka, Akihisa, Hamada, Gerson Shigueaki, López-Carrillo, Lizbeth, Hernández-Ramírez, Raúl Ulise, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Martin, Vicente, Ward, Mary H, Vioque, Jesu, Garcia de la Hera, Manoli, Zhang, Zuo-Feng, Kurtz, Robert C, Lagiou, Pagona, Lagiou, Areti, Trichopoulou, Antonia, Karakatsani, Anna, Malekzadeh, Reza, Camargo, M Costanza, Curado, Maria Paula, Boccia, Stefania, Boffetta, Paolo, Negri, Eva, La Vecchia, Carlo, Lunet, Nuno, and Boccia, Stefania (ORCID:0000-0002-1864-749X)

Abstract

Objective: This study aimed to evaluate and quantify the relationship between coffee and gastric cancer using a uniquely large dataset from an international consortium of observational studies on gastric cancer, including data from 18 studies, for a total of 8198 cases and 21 419 controls. Methods: A two-stage approach was used to obtain the pooled odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) for coffee drinkers versus never or rare drinkers. A one-stage logistic mixed-effects model with a random intercept for each study was used to estimate the dose-response relationship. Estimates were adjusted for sex, age and the main recognized risk factors for gastric cancer. Results: Compared to never or rare coffee drinkers, the estimated pooled OR for coffee drinkers was 1.03 (95% CI, 0.94-1.13). When the amount of coffee intake was considered, the pooled ORs were 0.91 (95% CI, 0.81-1.03) for drinkers of 1-2 cups per day, 0.95 (95% CI, 0.82-1.10) for 3-4 cups, and 0.95 (95% CI, 0.79-1.15) for five or more cups. An OR of 1.20 (95% CI, 0.91-1.58) was found for heavy coffee drinkers (seven or more cups of caffeinated coffee per day). A positive association emerged for high coffee intake (five or more cups per day) for gastric cardia cancer only. Conclusions: These findings better quantify the previously available evidence of the absence of a relevant association between coffee consumption and gastric cancer.

Published
2021

3. Education and gastric cancer risk-An individual participant data meta-analysis in the StoP project consortium

Author

Rota, Matteo, Alicandro, Gianfranco, Pelucchi, Claudio, Bonzi, Rossella, Bertuccio, Paola, Hu, Jinfu, Zhang, Zuo-Feng, Johnson, Kenneth C, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Galeone, Carlotta, López-Carrillo, Lizbeth, Muscat, Joshua, Lunet, Nuno, Ferro, Ana, Ye, Weimin, Plymoth, Amelie, Malekzadeh, Reza, Zaridze, David, Maximovitch, Dmitry, Kogevinas, Manoli, Fernández de Larrea, Nerea, Vioque, Jesu, Navarrete-Muñoz, Eva M, Tsugane, Shoichiro, Hamada, Gerson S, Hidaka, Akihisa, Pakseresht, Mohammadreza, Wolk, Alicja, Håkansson, Nicla, Hernández-Ramírez, Raúl Ulise, López-Cervantes, Malaquia, Ward, Mary, Pourfarzi, Farhad, Mu, Lina, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Boccia, Stefania, Negri, Eva, La Vecchia, Carlo, Boccia, Stefania (ORCID:0000-0002-1864-749X), Rota, Matteo, Alicandro, Gianfranco, Pelucchi, Claudio, Bonzi, Rossella, Bertuccio, Paola, Hu, Jinfu, Zhang, Zuo-Feng, Johnson, Kenneth C, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Galeone, Carlotta, López-Carrillo, Lizbeth, Muscat, Joshua, Lunet, Nuno, Ferro, Ana, Ye, Weimin, Plymoth, Amelie, Malekzadeh, Reza, Zaridze, David, Maximovitch, Dmitry, Kogevinas, Manoli, Fernández de Larrea, Nerea, Vioque, Jesu, Navarrete-Muñoz, Eva M, Tsugane, Shoichiro, Hamada, Gerson S, Hidaka, Akihisa, Pakseresht, Mohammadreza, Wolk, Alicja, Håkansson, Nicla, Hernández-Ramírez, Raúl Ulise, López-Cervantes, Malaquia, Ward, Mary, Pourfarzi, Farhad, Mu, Lina, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Boccia, Stefania, Negri, Eva, La Vecchia, Carlo, and Boccia, Stefania (ORCID:0000-0002-1864-749X)

Abstract

Low socioeconomic position (SEP) is a strong risk factor for incidence and premature mortality from several cancers. Our study aimed at quantifying the association between SEP and gastric cancer (GC) risk through an individual participant data meta-analysis within the “Stomach cancer Pooling (StoP) Project”. Educational level and household income were used as proxies for the SEP. We estimated pooled odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) across levels of education and household income by pooling study-specific ORs through random-effects meta-analytic models. The relative index of inequality (RII) was also computed. A total of 9,773 GC cases and 24,373 controls from 25 studies from Europe, Asia and America were included. The pooled OR for the highest compared to the lowest level of education was 0.60 (95% CI, 0.44–0.84), while the pooled RII was 0.45 (95% CI, 0.29–0.69). A strong inverse association was observed both for noncardia (OR 0.39, 95% CI, 0.22–0.70) and cardia GC (OR 0.47, 95% CI, 0.22–0.99). The relation was stronger among H. pylori negative subjects (RII 0.14, 95% CI, 0.04–0.48) as compared to H. pylori positive ones (RII 0.29, 95% CI, 0.10–0.84), in the absence of a significant interaction (p = 0.28). The highest household income category showed a pooled OR of 0.65 (95% CI, 0.48–0.89), while the corresponding RII was 0.40 (95% CI, 0.22–0.72). Our collaborative pooled-analysis showed a strong inverse relationship between SEP indicators and GC risk. Our data call for public health interventions to reduce GC risk among the more vulnerable groups of the population.

Published
2020

4. Allium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project

Author

Michela Dalmartello, Federica Turati, Zuo-Feng Zhang, Nuno Lunet, Matteo Rota, Rossella Bonzi, Carlotta Galeone, Georgia Martimianaki, Domenico Palli, Monica Ferraroni, Guo-Pei Yu, Samantha Morais, Reza Malekzadeh, Lizbeth López-Carrillo, David Zaridze, Dmitry Maximovitch, Nuria Aragonés, Guillermo Fernández-Tardón, Vicente Martin, Jesus Vioque, Manoli Garcia de la Hera, Maria Paula Curado, Felipe Jose Fernandez Coimbra, Paulo Assumpcao, Mohammadreza Pakseresht, Jinfu Hu, Raúl Ulises Hernández-Ramírez, Mary H. Ward, Farhad Pourfarzi, Lina Mu, Shoichiro Tsugane, Akihisa Hidaka, Pagona Lagiou, Areti Lagiou, Antonia Trichopoulou, Anna Karakatsani, Paolo Boffetta, M. Costanza Camargo, Eva Negri, Carlo La Vecchia, Claudio Pelucchi, Dalmartello, Michela, Turati, Federica, Zhang, Zuo-Feng, Lunet, Nuno, Rota, Matteo, Bonzi, Rossella, Galeone, Carlotta, Martimianaki, Georgia, Palli, Domenico, Ferraroni, Monica, Yu, Guo-Pei, Morais, Samantha, Malekzadeh, Reza, López-Carrillo, Lizbeth, Zaridze, David, Maximovitch, Dmitry, Aragonés, Nuria, Fernández-Tardón, Guillermo, Martin, Vicente, Vioque, Jesu, Garcia de la Hera, Manoli, Curado, Maria Paula, Coimbra, Felipe Jose Fernandez, Assumpcao, Paulo, Pakseresht, Mohammadreza, Hu, Jinfu, Hernández-Ramírez, Raúl Ulise, Ward, Mary H, Pourfarzi, Farhad, Mu, Lina, Tsugane, Shoichiro, Hidaka, Akihisa, Lagiou, Pagona, Lagiou, Areti, Trichopoulou, Antonia, Karakatsani, Anna, Boffetta, Paolo, Camargo, M Costanza, Negri, Eva, La Vecchia, Carlo, and Pelucchi, Claudio

Subjects
Cancer Research, gastric cancer, Oncology and Carcinogenesis, Article, Diet, Oncology, Clinical Research, Risk Factors, Stomach Neoplasms, Case-Control Studies, Vegetables, Public Health and Health Services, Humans, Oncology & Carcinogenesis, Garlic, Cancer
Abstract

BACKGROUND: The role of allium vegetables on gastric cancer (GC) risk remains unclear. METHODS: We evaluated whether higher intakes of allium vegetables reduce GC risk using individual participant data from 17 studies participating in the "Stomach cancer Pooling (StoP) Project", including 6097 GC cases and 13,017 controls. Study-specific odds ratios (ORs) were pooled using a two-stage modelling approach. RESULTS: Total allium vegetables intake was inversely associated with GC risk. The pooled OR for the highest versus the lowest study-specific tertile of consumption was 0.71 (95% confidence interval, CI, 0.56-0.90), with substantial heterogeneity across studies (I(2) > 50%). Pooled ORs for high versus low consumption were 0.69 (95% CI, 0.55-0.86) for onions and 0.83 (95% CI, 0.75-0.93) for garlic. The inverse association with allium vegetables was evident in Asian (OR 0.50, 95% CI, 0.29-0.86) but not European (OR 0.96, 95% CI, 0.81-1.13) and American (OR 0.66, 95% CI, 0.39-1.11) studies. Results were consistent across all other strata. CONCLUSIONS: In a worldwide consortium of epidemiological studies, we found an inverse association between allium vegetables and GC, with a stronger association seen in Asian studies. The heterogeneity of results across geographic regions and possible residual confounding suggest caution in results interpretation.

Published
2022

5. Meat intake and risk of gastric cancer in the Stomach cancer Pooling (StoP) project

Author

Shoichiro Tsugane, Bárbara Peleteiro, David Zaridze, Malaquías López-Cervantes, Ana Rute Costa, Eva Negri, Mary H. Ward, Domenico Palli, Reza Malekzadeh, Roberto Persiani, Ana Ferro, Paolo Boffetta, Rossella Bonzi, Raul U. Hernandez-Ramirez, Robert C. Kurtz, Jinfu Hu, Claudio Pelucchi, Jesús Vioque, Carlo La Vecchia, Valentina Rosato, Stefania Boccia, Gerson Shigueaki Hamada, Nuria Aragonés, M. Constanza Camargo, Vicente Martín, Matteo Rota, Kenneth C. Johnson, Nuno Lunet, Guo-Pei Yu, Pagona Lagiou, Paola Bertuccio, Dmitry Maximovitch, Samantha Morais, Monica Ferraroni, Farhad Pourfarzi, Lina Mu, Maria Paula Curado, Zuo-Feng Zhang, Lizbeth López-Carrillo, Eva María Navarrete-Muñoz, Areti Lagiou, Akihisa Hidaka, Ferro, Ana, Rosato, Valentina, Rota, Matteo, Costa, Ana Rute, Morais, Samantha, Pelucchi, Claudio, Johnson, Kenneth C, Hu, Jinfu, Palli, Domenico, Ferraroni, Monica, Zhang, Zuo-Feng, Bonzi, Rossella, Yu, Guo-Pei, Peleteiro, Bárbara, López-Carrillo, Lizbeth, Tsugane, Shoichiro, Hamada, Gerson Shigueaki, Hidaka, Akihisa, Zaridze, David, Maximovitch, Dmitry, Vioque, Jesu, Navarrete-Munoz, Eva M, Aragonés, Nuria, Martín, Vicente, Hernández-Ramírez, Raúl Ulise, Bertuccio, Paola, Ward, Mary H, Malekzadeh, Reza, Pourfarzi, Farhad, Mu, Lina, Lópes-Cervantes, Malaquia, Persiani, Roberto, Kurtz, Robert C, Lagiou, Areti, Lagiou, Pagona, Boffetta, Paolo, Boccia, Stefania, Negri, Eva, Camargo, M Constanza, Curado, Maria Paula, La Vecchia, Carlo, Lunet, Nuno, and Instituto de Saúde Pública da Universidade do Porto

Subjects
Adult, Male, Cancer Research, Meat, Settore MED/18 - CHIRURGIA GENERALE, Pooling, Oncology and Carcinogenesis, Article, Cohort Studies, 03 medical and health sciences, meat, 0302 clinical medicine, Clinical Research, medicine, Humans, Processed meat, Food science, Oncology & Carcinogenesis, Stomach cancer, Settore MED/42 - IGIENE GENERALE E APPLICATA, Meat intake, Aged, Cancer, stomach neoplasms, business.industry, pooled analysis, food and beverages, Odds ratio, Middle Aged, medicine.disease, diet, nutrition, Diet, Meat Products, Red Meat, Increased risk, Pooled analysi, Oncology, diet, meat, nutrition, pooled analysis, stomach neoplasms, 030220 oncology & carcinogenesis, Case-Control Studies, Red meat, Female, business
Abstract

The consumption of processed meat has been associated with noncardia gastric cancer, but evidence regarding a possible role of red meat is more limited. Our study aims to quantify the association between meat consumption, namely white, red and processed meat, and the risk of gastric cancer, through individual participant data meta-analysis of studies participating in the “Stomach cancer Pooling (StoP) Project”. Data from 22 studies, including 11,443 cases and 28,029 controls, were used. Study-specific odds ratios (ORs) were pooled through a two-stage approach based on random-effects models. An exposure-response relationship was modeled, using one and two-order fractional polynomials, to evaluate the possible nonlinear association between meat intake and gastric cancer. An increased risk of gastric cancer was observed for the consumption of all types of meat (highest vs. lowest tertile), which was statistically significant for red (OR: 1.24; 95% CI: 1.00–1.53), processed (OR: 1.23; 95% CI: 1.06–1.43) and total meat (OR: 1.30; 95% CI: 1.09–1.55). Exposure-response analyses showed an increasing risk of gastric cancer with increasing consumption of both processed and red meat, with the highest OR being observed for an intake of 150 g/day of red meat (OR: 1.85; 95% CI: 1.56–2.20). This work provides robust evidence on the relation between the consumption of different types of meat and gastric cancer. Adherence to dietary recommendations to reduce meat consumption may contribute to a reduction in the burden of gastric cancer. Our study was supported by the Associazione Italiana per la Ricerca sul Cancro (AIRC), Project no. 21378 (Investigator Grant), by the Italian Ministry of Health (Young Researchers, GR-2011-02347943 to SB), by the Italian League for the Fight Against Cancer (LILT) and by the Associazione Industriale delle Carni e dei Salumi (ASSICA, to the Department of Clinical Sciences and Community Health, University of Milan). Our study was also funded by FEDER through the Operational Programme Competitiveness and Internationalization and national funding from the Foundation for Science and Technology – FCT (Portuguese Ministry of Science, Technology and Higher Education) under the Unidade de Investigação em Epidemiologia – Instituto de Saúde Pública da Universidade do Porto (EPIUnit) (POCI-01-0145-FEDER-006862; Ref. UID/DTP/04750/2013). AF (PD/BD/105823/2014) was awarded with an individual scholarship through national funding from FCT/MCTES. Individual grants attributed to ARC (SFRH/BD/102181/2014), and BP (SFRH/BPD/108751/2015) were funded by the FCT and the “Programa Operacional Capital Humano” (POCH/SE). SM was funded under the project “NEON-PC - Neuro-oncological complications of prostate cancer: longitudinal study of cognitive decline “ (POCI-01-0145-FEDER-032358; Ref. PTDC/SAU-EPI/32358/2017). Valentina Rosato was supported by a fellowship by the Italian Foundation for Cancer Research (FIRC #18104).

Published
2020

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