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Objective: the exact prevalence of obesity in Mexico is not well known and varies between sources, but more than 30% of Mexico’s population are obese. Obesity is associated with several diseases such as metabolic syndrome; the latter, along with cancer, have become public health concerns worldwide, and their association has been widely studied in developed countries. The aim of this study was to identify the overall prevalence of metabolic syndrome and to describe its characteristics among first-time cancer patients at a referral center in Mexico. Methods: a prospective, observational, cohort study of first-time patients of the National Cancer Institute of Mexico in the period of September 2016-2017. We identified 1,165 first-time patients, and 316 patients with known or recently diagnosed metabolic syndrome were included. Results: median age was 55 years old and most were female (81%). The most frequent tumors were breast, gynecological, and hematological growths. Obesity (class 1-3) and abnormal glucose and/or previous diabetes mellitus diagnosis were mostly observed in patients with skin and soft tissue tumors; dyslipidemia, high triglycerides, and/or low HDL-cholesterol were mostly observed in patients with gastrointestinal tumors. Conclusion: the prevalence of metabolic syndrome among first-time cancer patients was 27%. As obesity and cancer are of public concern in Mexico, the implementation of preventive strategies for metabolic syndrome patients, focusing on the first level of care during early stages in order to reduce the risk of cancer, is needed. Resumen Objetivo: la prevalencia de la obesidad en México es mayor del 30% de la población total. La obesidad se asocia con diversas enfermedades, entre ellas el síndrome metabólico; este y el cáncer se han convertido en problemas de salud pública a nivel mundial, y su asociación ha sido ampliamente estudiada en países desarrollados. El objetivo de este estudio fue identificar la prevalencia del síndrome metabólico y describir las características entre pacientes oncológicos de primera vez en un hospital de tercer nivel en México. Métodos: estudio prospectivo, observacional y de cohortes que incluye a pacientes oncológicos atendidos por primera vez en el Instituto Nacional de Cancerología durante el periodo de septiembre 2016 a 2017. Identificamos 1165 pacientes; 316 tenían el diagnóstico de síndrome metabólico y fueron incluidos en el presente estudio. Resultados: la mediana de edad fue de 55 años y la mayoría de los pacientes eran del sexo femenino (81%). Las neoplasias más frecuentes fueron las de mama, ginecológicas y hematológicas. La obesidad (clase 1-3) y la glucosa anormal y/o un diagnóstico previo de diabetes mellitus se observaron mayormente en pacientes con neoplasias de piel y tejidos blandos; los pacientes con neoplasias gastrointestinales presentaron mayormente dislipidemia, triglicéridos elevados y/o HDL bajo. Conclusiones: la prevalencia del síndrome metabólico en nuestros pacientes oncológicos fue de 27%. Al ser la obesidad y el cáncer problemas de salud pública en México, la implementación de medidas preventivas para pacientes con síndrome metabólico debe enfocarse en el primer nivel de atención, durante etapas tempranas, para poder reducir el riesgo de cáncer.

Objective. To determine the psychometric properties of Goldberg’s General Health Questionnaire –GHQ-28– in a sample of Mexican primary caregivers of cancer patients. Method: Two hundred and seventy six caregivers participated in this protocol, 205 of which were women (74.3%) and 71 were men (25.7%). Participants answered the GHQ-28 and the Beck Depression Inventory (BDI) concurrently. Results. The internal consistency of the overall scale showed a satisfactory index (α = 0.91). The Cronbach alphas of the subscale had a value of α = .86, α = .76, explaining the 53.42% of the variance. The correlation validity by BDI showed significant outcomes (Pearson r= 0.723 - 0.427, p

Objective: the exact prevalence of obesity in Mexico is not well known and varies between sources, but more than 30% of Mexico’s population are obese. Obesity is associated with several diseases such as metabolic syndrome; the latter, along with cancer, have become public health concerns worldwide, and their association has been widely studied in developed countries. The aim of this study was to identify the overall prevalence of metabolic syndrome and to describe its characteristics among first-time cancer patients at a referral center in Mexico. Methods: a prospective, observational, cohort study of first-time patients of the National Cancer Institute of Mexico in the period of September 2016-2017. We identified 1,165 first-time patients, and 316 patients with known or recently diagnosed metabolic syndrome were included. Results: median age was 55 years old and most were female (81%). The most frequent tumors were breast, gynecological, and hematological growths. Obesity (class 1-3) and abnormal glucose and/or previous diabetes mellitus diagnosis were mostly observed in patients with skin and soft tissue tumors; dyslipidemia, high triglycerides, and/or low HDL-cholesterol were mostly observed in patients with gastrointestinal tumors. Conclusion: the prevalence of metabolic syndrome among first-time cancer patients was 27%. As obesity and cancer are of public concern in Mexico, the implementation of preventive strategies for metabolic syndrome patients, focusing on the first level of care during early stages in order to reduce the risk of cancer, is needed.

Objective: The aims of this study were to describe the incidence of obesity and overweight in critically ill cancer patients, and to evaluate the clinical characteristics and Intensive Care Unit (ICU) outcomes of critically ill cancer patients with obesity and overweight. Methods: An observational cohort study. There were no interventions. Results: During the study period, 483 critically ill cancer patients were admitted to ICU, and 59.2% of them (258 patients) had high body mass index (BMI). Comparing the groups of patients with BMI < 25 kg/m² and ≥ 25 kg/m², we observed that those with BMI ≥ 25 kg/m² were older at the time of admission to the ICU. The global mortality in ICU was of 22.4%. ICU mortality was similar between patients with BMI < 25 kg/m² and ≥ 25 kg/m² (21.3% versus 23.0%, p = 0.649). Univariate analysis indicated that the following five factors were associated with ICU death in patients with BMI ≥ 25 kg/m² as the outcome variable of interest: age, sepsis, invasive mechanical ventilation, type 2 diabetes, ≥ two organ failures. Multivariate analysis identified ≥ two organ failures as independent prognostic factor of ICU death. Conclusion: Critically ill cancer patients have a high incidence of high BMI; approximately six of every ten patients admitted to the ICU with a serious condition are overweight or show several degrees of obesity. The ICU mortality of the patients with a body mass index < 25 kg/m² and ≥ 25 kg/m² was similar. The independent prognostic factor of ICU death in critically ill patients with a BMI ≥ 25 kg/m² was the number of organ dysfunctions, especially when two or more organs were affected. Objetivo: Describir la incidencia de obesidad y sobrepeso en pacientes graves con cáncer y evaluar las características clínicas y el pronóstico de los pacientes oncológicos gravemente enfermos con sobrepeso y obesidad. Métodos: Estudio observacional y descriptivo. No se realizó ninguna intervención. Resultados: Durante el periodo de estudio, 483 pacientes graves con cáncer fueron ingresados a la unidad de cuidados intensivos (UCI); el 59.2% (258 pacientes) tuvo índice de masa corporal (IMC) elevado. Al comparar los pacientes con IMC < 25 kg/m² y con IMC ≥ 25 kg/m², se observó que los pacientes con IMC ≥ 25 kg/m² eran de mayor edad al momento de ingresar en la UCI. La mortalidad en la UCI fue del 22.4%. La mortalidad fue similar en los grupos con IMC < 25 kg/m² y ≥ 25 kg/m² (21.3% versus 23.0%, p = 0.649). El análisis multivariado determinó que las siguientes variables fueron asociadas con muerte en la UCI en el grupo de pacientes con IMC ≥ 25 kg/m²: edad, sepsis, ventilación mecánica invasiva, diabetes mellitus tipo 2 y cursar con dos o más fallas orgánicas. El análisis multivariado identificó como factor pronóstico independiente para muerte en la UCI cursar con dos o más fallas orgánicas. Conclusión: los pacientes graves con cáncer tienen una alta incidencia de IMC elevado; aproximadamente seis de cada diez pacientes ingresados en la UCI con una condición que pone en peligro la vida tienen sobrepeso o son obesos. La mortalidad fue similar en los grupos con IMC < 25 kg/m² y ≥ 25 kg/m². En el grupo de pacientes con IMC ≥ 25 kg/m² se identificó como factor pronóstico independiente para muerte en UCI el número de fallas orgánicas especialmente cuando dos o más órganos están afectados.