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1. Potential population-level effects of HIV self-test distribution among key populations in Côte d'Ivoire, Mali, and Senegal: a mathematical modelling analysis

Author

Amani, Elvis Georges, Badiane, Kéba, Bayac, Céline, Bekelynck, Anne, Boily, Marie-Claude, Boye, Sokhna, Breton, Guillaume, d'Elbée, Marc, Desclaux, Alice, Desgrées du Loû, Annabel, Diop, Papa Moussa, Ehui, Eboi, Medley, Graham, Jean, Kévin, Keita, Abdelaye, Kouassi, Arsène Kra, Ky-Zerbo, Odette, Larmarange, Joseph, Maheu-Giroux, Mathieu, Moh, Raoul, Mosso, Rosine, Ndour, Cheikh Tidiane, Paltiel, David, Pourette, Dolorès, Rouveau, Nicolas, Silhol, Romain, Simo Fotso, Arlette, Terris-Prestholt, Fern, Traoré, Métogara Mohamed, Doumenc-Aïdara, Clémence, Geoffroy, Olivier, Kabemba, Odé Kanku, Vautier, Anthony, Abokon, Armand, Anoma, Camille, Diokouri, Annie, Kouamé, Blaise, Kouakou, Venance, Koffi, Odette, Kpolo, Alain, Tety, Josiane, Traore, Yacouba, Bagendabanga, Jules, Berthé, Djelika, Diakité, Daouda, Diakité, Mahamadou, Diallo, Youssouf, Daouda, Minta, Hessou, Septime, Kanambaye, Saidou, Kanouté, Abdul Karim, Dembélé Keita, Bintou, Koné, Dramane, Koné, Mariam, Maiga, Almoustapha, Saran Keita, Aminata, Sidibé, Fadiala, Tall, Madani, Yattassaye Camara, Adam, Sanogo, Abdoulaye, Bâ, Idrissa, Diallo, Papa Amadou Niang, Fall, Fatou, NGom Guèye, NDèye Fatou, Ndiaye, Sidy Mokhtar, Niang, Alassane Moussa, Samba, Oumar, Thiam, Safiatou, Turpin, Nguissali M.E., Bouaré, Seydou, Camara, Cheick Sidi, Kouadio, Brou Alexis, Sarrassat, Sophie, Sow, Souleyman, Eponon Ehua, Agnes, Kouvahe, Amélé, Montaufray, Marie-Anne, Ndeye, Pauline Dama, Soni, Nirali, N'Guessan, Kouassi Noel, Sidibé, Younoussa, Gueye, Papa Alioune, Mukandavire, Christinah, and Vickerman, Peter

Published
2024
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2. Potential population-level effects of HIV self-test distribution among key populations in Côte d'Ivoire, Mali, and Senegal: a mathematical modelling analysis

Author

Silhol, Romain, Maheu-Giroux, Mathieu, Soni, Nirali, Simo Fotso, Arlette, Rouveau, Nicolas, Vautier, Anthony, Doumenc-Aïdara, Clémence, Geoffroy, Olivier, N'Guessan, Kouassi Noel, Sidibé, Younoussa, Kabemba, Odé Kanku, Gueye, Papa Alioune, Ndeye, Pauline Dama, Mukandavire, Christinah, Vickerman, Peter, Keita, Abdelaye, Ndour, Cheikh Tidiane, Larmarange, Joseph, Boily, Marie-Claude, Amani, Elvis Georges, Badiane, Kéba, Bayac, Céline, Bekelynck, Anne, Boily, Marie-Claude, Boye, Sokhna, Breton, Guillaume, d'Elbée, Marc, Desclaux, Alice, Desgrées du Loû, Annabel, Diop, Papa Moussa, Ehui, Eboi, Medley, Graham, Jean, Kévin, Keita, Abdelaye, Kouassi, Arsène Kra, Ky-Zerbo, Odette, Larmarange, Joseph, Maheu-Giroux, Mathieu, Moh, Raoul, Mosso, Rosine, Ndour, Cheikh Tidiane, Paltiel, David, Pourette, Dolorès, Rouveau, Nicolas, Silhol, Romain, Simo Fotso, Arlette, Terris-Prestholt, Fern, Traoré, Métogara Mohamed, Doumenc-Aïdara, Clémence, Geoffroy, Olivier, Kabemba, Odé Kanku, Vautier, Anthony, Abokon, Armand, Anoma, Camille, Diokouri, Annie, Kouamé, Blaise, Kouakou, Venance, Koffi, Odette, Kpolo, Alain, Tety, Josiane, Traore, Yacouba, Bagendabanga, Jules, Berthé, Djelika, Diakité, Daouda, Diakité, Mahamadou, Diallo, Youssouf, Daouda, Minta, Hessou, Septime, Kanambaye, Saidou, Kanouté, Abdul Karim, Dembélé Keita, Bintou, Koné, Dramane, Koné, Mariam, Maiga, Almoustapha, Saran Keita, Aminata, Sidibé, Fadiala, Tall, Madani, Yattassaye Camara, Adam, Sanogo, Abdoulaye, Bâ, Idrissa, Diallo, Papa Amadou Niang, Fall, Fatou, NGom Guèye, NDèye Fatou, Ndiaye, Sidy Mokhtar, Niang, Alassane Moussa, Samba, Oumar, Thiam, Safiatou, Turpin, Nguissali M.E., Bouaré, Seydou, Camara, Cheick Sidi, Kouadio, Brou Alexis, Sarrassat, Sophie, Sow, Souleyman, Eponon Ehua, Agnes, Kouvahe, Amélé, Montaufray, Marie-Anne, and Ndeye, Pauline Dama

Abstract

During 2019–21, the AutoTest VIH, Libre d'accéder à la connaissance de son Statut (ATLAS) programme distributed around 380 000 HIV self-testing kits to key populations, including female sex workers, men who have sex with men, and their partners, in Côte d'Ivoire, Mali, and Senegal. We aimed to estimate the effects of the ATLAS programme and national scale-up of HIV self-test distribution on HIV diagnosis, HIV treatment coverage, HIV incidence, and HIV-related mortality.

Published
2024
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4. Biological markers of musculoskeletal pain: A scoping review—protocol registration

Author

DJADE, Codjo, HESSOU, Septime, TOI, Alfred, DIORIO, Caroline, LAURIN, Danielle, Gogovor, Amédé, SIDIBE, Aboubacar, Ekanmian, Giraud, Zomahoun, Hervé, and DIONNE, Clermont

Subjects
Medicine and Health Sciences
Abstract

Musculoskeletal pain is the leading contributor to disability, limiting mobility and dexterity, and often leads to early retirement from work, lower levels of well-being, and reduced ability to participate in society. Musculoskeletal pain, especially in its persistent (“chronic”) form, is one of the most important causes of disability and generates an enormous burden for health and social care systems globally. However, the underlying mechanisms of musculoskeletal pain are not well understood. Recently, poor sleep, stress, unhealthy diet, and obesity have received much attention in the search for risk and prognostic factors of musculoskeletal pain. Our understanding of musculoskeletal pain has thus evolved from a strictly biomechanical perspective to a broader approach. Hence, it becomes more and more plausible that biomarkers may play a significant role in the diagnosis and prognosis of musculoskeletal pain. The objective of this scoping review is to provide an overview and mapping of the literature on the associations between biomarkers and musculoskeletal pain.

Published
2022
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5. Notes de politique

Author

Larmarange, Joseph, Amani Elvis, Georges, Badiane, Kéba, Bayac, Céline, Bekelynck, Anne, Boily, Marie-Claude, Boye, Sokhna, Breton, Guillaume, d’Elbée, Marc, Desclaux, Alice, Desgrées du Loû, Annabel, Diop Papa, Moussa, Doumenc-Aïdara, Clémence, Ehui, Eboi, Jean, Kévin, Keita, Abdelaye, Kouadio Brou, Alexis, Kouassi Kra, Arsène, Ky-Zerbo, Odette, Maheu-Giroux, Mathieu, Medley, Graham, Moh, Raoul, Ndour Cheikh, Tidiane, Pourette, Dolorès, Rouveau, Nicolas, Silhol, Romain, Simo Fotso, Arlette, Terris-Prestholt, Fern, Traore Métogara, Mohamed, Vautier, Anthony, Diallo, Sanata, Gueye Papa, Alioune, Geoffroy, Olivier, Kabemba Odé, Kanku, Abokon, Armand, Anoma, Camille, Diokouri, Annie, Kouame, Blaise, Kouakou, Venance, Koffi, Odette, Kpolo, Alain-Michel, Tety, Josiane, Traore, Yacouba, Bagendabanga, Jules, Berthé, Djelika, Diakite, Daouda, Diakité, Mahamadou, Diallo, Youssouf, Daouda, Minta, Hessou, Septime, Kanambaye, Saidou, Kanoute Abdul, Karim, Keita Dembele, Bintou, Koné, Dramane, Koné, Mariam, Maiga, Almoustapha, Nouhoum, Telly, Sanogo, Abdoulaye, Saran Keita, Aminata, Sidibé, Fadiala, Tall, Madani, Yattassaye Camara, Adam, Bâ, Idrissa, Diallo Papa Amadou, Niang, Fall, Fatou, Guèye Ndèye Fatou, Ngom, Ndiaye Sidy, Mokhtar, Niang Alassane, Moussa, Samba, Oumar, Thiam, Safiatou, Turpin Nguissali, M.E., Bouaré, Seydou, Camara Cheick, Sidi, Eponon Ehua, Agnes, Kouvahe, Amélé, Montaufray, Marie-Anne, Mosso, Rosine, Ndeye Pauline, Dama, Sarrassat, Sophie, Sow, Souleymane, Centre population et développement (CEPED - UMR_D 196), Institut de Recherche pour le Développement (IRD)-Université Paris Cité (UPCité), Santé, vulnérabilités et relations de genre au sud (SAGESUD - ERL Inserm U1244), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre population et développement (CEPED - UMR_D 196), Institut de Recherche pour le Développement (IRD)-Université Paris Cité (UPCité)-Institut de Recherche pour le Développement (IRD)-Université Paris Cité (UPCité), Programme PAC-CI, ANRS France Recherche Nord & sud Sida-hiv hépatites, Solidarité thérapeutique & initiatives contre le sida (SOLTHIS), Imperial College London, London School of Hygiene and Tropical Medicine (LSHTM), Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes (TransVIHMI), Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Programme National de Lutte contre le Sida [Abidjan, Côte d'Ivoire] (PNLS), Laboratoire Modélisation, épidémiologie et surveillance des risques sanitaires (MESuRS), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Institut National de Recherche en Santé Publique [Bamako] (INRSP), Institut d'ethnologie méditerranéenne, européenne et comparative (IDEMEC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), McGill University = Université McGill [Montréal, Canada], Division de Lutte contre le Sida et les IST (DLSI), Ministère de la Santé et de la Prévention, Fondation Ariel Glaser pour la lutte contre le SIDA Pédiatrique, Espace Confiance [Abidjan, Côte d’Ivoire], Heartland Alliance, Aprosam, Ruban Rouge, Blety, Orasur, FHI 360, PSI, CNLS, Dayanaso, CSLS/MSHP, Comité scientifique VIH du Mali, Plan Mali, ARCAD Santé PLUS [Bamako, Mali], AKS Mali, Amprode Sahel, Soutoura, CEPIAD, Comité National de Lutte contre le Sida du Sénégal (CNLS), Ministère de la santé-CNLS, CTA, ENDA Santé, Ecole Nationale Supérieure de l'Electronique et de ses Applications (ENSEA), Unitaid ATLAS, Institut de recherche pour le développement, Solthis, and ATLAS (Unitaid)

Subjects
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, [SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnology, [SHS.DEMO]Humanities and Social Sciences/Demography, [SHS.ECO]Humanities and Social Sciences/Economics and Finance, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation
Published
2022

6. Acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in Benin : a qualitative study

Author

Gning, Ndeye Ndiagna, Guédou, Fernand Aimé, Diabate, Souleymane, Hessou, Septime, Batona, Georges, Béhanzin, Luc, Alary, Michel, Ahouada, Carin, Zannou, Marcel D., Gning, Ndeye Ndiagna, Guédou, Fernand Aimé, Diabate, Souleymane, Hessou, Septime, Batona, Georges, Béhanzin, Luc, Alary, Michel, Ahouada, Carin, and Zannou, Marcel D.

Abstract

In Benin, consistent condom use among men who have sex with men (MSM) is relatively low and providing them with Pre-exposure prophylaxis (PrEP) could be of great relevance. We aimed to describe PrEP knowledge and intention to use it; identify key facilitators and barriers to PrEP; and describe the perceived impact of PrEP on unsafe sexual behavior. MSM, 18 years or older, HIV-negative or of unknown status, were enrolled in five cities of Benin. Intention to use PrEP was assessed through five focus groups (FG). Data were analyzed using manual thematic sorting. Thirty MSM (six per city) participated in the FG. Mean age (standard deviation) was 27.1 (5.0) years. All participants expressed the intention to use PrEP if made available. Facilitators of PrEP use were: availability of medication, safety, absence of constraints as well as freedom to have multiple sex partners and sex with HIV-positive friends. Barriers were: complex procedures for obtaining medication, size and taste of medication, cost of medication, poor PrEP awareness.. Eighteen men admitted that PrEP could lead to decrease in or even abandonment of condom use. In conclusion, MSM showed openness to use PrEP if available, although they recognized that it could lead to risk compensation.

Published
2020

9. Acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in Benin : a qualitative study

Author

Ahouada, Carin, Diabate, Souleymane, Gning, Ndeye Ndiagna, Hessou, Septime, Batona, Georges, Guédou, Fernand Aimé, Béhanzin, Luc, Zannou, Marcel D., Alary, Michel, Ahouada, Carin, Diabate, Souleymane, Gning, Ndeye Ndiagna, Hessou, Septime, Batona, Georges, Guédou, Fernand Aimé, Béhanzin, Luc, Zannou, Marcel D., and Alary, Michel

Abstract

In Benin, consistent condom use among men who have sex with men (MSM) is relatively low and providing them with Pre-exposure prophylaxis (PrEP) could be of great relevance. We aimed to describe PrEP knowledge and intention to use it; identify key facilitators and barriers to PrEP; and describe the perceived impact of PrEP on unsafe sexual behavior. MSM, 18 years or older, HIV-negative or of unknown status, were enrolled in five cities of Benin. Intention to use PrEP was assessed through five focus groups (FG). Data were analyzed using manual thematic sorting. Thirty MSM (six per city) participated in the FG. Mean age (standard deviation) was 27.1 (5.0) years. All participants expressed the intention to use PrEP if made available. Facilitators of PrEP use were: availability of medication, safety, absence of constraints as well as freedom to have multiple sex partners and sex with HIV-positive friends. Barriers were: complex procedures for obtaining medication, size and taste of medication, cost of medication, poor PrEP awareness.. Eighteen men admitted that PrEP could lead to decrease in or even abandonment of condom use. In conclusion, MSM showed openness to use PrEP if available, although they recognized that it could lead to risk compensation.

Published
2019

10. Trans-identity in Benin: Fact or Fiction? Social Response and Consequences

Author

Hessou, Septime, primary, Ahanhanzo, Yolaine Glèlè, additional, Kpozèhouen, Alphonse, additional, Yadouleton, Tranquilin, additional, Sodoloufo, Odile, additional, Capo-chichi, Virgile, additional, Doussoh, Bruno, additional, Gnahoui-David, Bernard, additional, Biaou, Alphonse, additional, and Azandjèmè, Colette, additional

Published
2019
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12. Étude ethnobotanique, phytochimique et écotoxicologique de Ocimum gratissimum Linn (Lamiaceae) à Cotonou

Author

Kpètèhoto, Wilfrid Hinnoutondji, Hessou, Septime, Dougnon, Victorien Tamègnon, Johnson, Roch Christian, Boni, Gratien, Houéto, Eustache Enock, Assogba, Fidèle, Pognon, Elias, Loko, Frédéric, Boko, Michel, and Gbénou, Joachim

Subjects
Ocimum gratissimum, Légume feuille, Plante médicinale, Ethnobotanique, Cotonou, Bénin, Ocimum gratissimum, Leaf vegetable, Medicinal plant, Ethnobotany, Benin
Abstract

Objectif: L’usage de Ocimum gratissimum Lamiaceae (Basilic tropical) est très répandu au Bénin. Cette utilisation repose sur les connaissances empiriques des populations. Il est légitime de se demander si les vertus attribuées à cette plante reposent sur des bases scientifiques et sa consommation sans conséquences néfastes pour la santé humaine.Méthodologie et résultats: Une étude ethnobotanique a ciblé les vendeurs de légumes feuilles des trois principaux marchés (Dantokpa ; Saint Michel ; Vêdoko), quelques phytothérapeutes, des agents de santé et des consommateurs de Cotonou la capitale de la République du Bénin. Elle a été complétée par une étude phytochimique basée sur des réactions de précipitations différentielles, complétée par le dosage des métaux lourds (Plomb ; Cadmium), de quelques éléments nutritifs et oligo-éléments par spectrophotométrie d’absorption moléculaire.Il ressort des investigations plusieurs usages de Ocimum gratissimum Linn (médicinal ; alimentaire ; rituel ; chimique ; ornemental). Cette plante renferme plusieurs groupes phytochimique (phénoliques ; azotés ; stéroïdes ; terpènes ; mucilages ; dérivés cyanogéniques), des éléments nutritifs (Protéines ; Azote ; Fer ; Zinc ; Cuivre). Par ailleurs, nos résultats montrent la présence de métaux lourds (Plomb ; Cadmium) dans des concentrations supérieures aux normes OMS.Conclusion et application des résultats: Les résultats des analyses phytochimiques et nutritionnelles confirment les usages empiriques identifiés lors de l’étude ethnobotanique. Cette plante est un remède dans la prévention et le traitement de certaines maladies, un complément alimentaire, une solution alternative dans la lutte chimique. Toutefois, la présence des Éléments Traces Métalliques avec des concentrations supérieures aux normes OMS traduit un risque potentiel pour la santé humaine. Il urge pour l’état central, les partenaires sociaux et la communauté scientifique de repenser la production de Ocimum gratissimum Linn de qualité phytosanitaire acceptable afin de garantir à la population l’usage sans risque de cette Plante Médicinale a caractère de Légumes feuilles, gage de bonne santé et de Développement Durable.Mots clés: Ocimum gratissimum ; Légume feuille ; Plante médicinale ; Ethnobotanique ; Cotonou ; BéninEnglish AbstractObjective: The use of Ocimum gratissimum Lamiaceae (African Basil) is widespread in Benin. This study evaluated whether the virtues attributed to this plant are focused on rational basis and that its consumption is without adverse consequences for human health.Methodology and Results: An ethnobotanical study targeting leaves from vegetable vendors in the three major markets (Dantokpa ; Saint Michel ; Vêdoko), some herbalists, health workers and consumers was conducted in Cotonou the capital city of Benin. A phytochemical study based on differential precipitation reactions was carried out, supplemented by the determination of heavy metals (lead, cadmium) and some nutrients by molecular absorption spectrophotometry.The investigations revealed several uses of Ocimum gratissimum Linn (Lamiaceae) i.e medicinal, food, ritual, chemical and ornamental. It contains phytochemicals compound such as phenolic; nitrogen; steroids; terpenes; mucilage; derived cyanogenic and several nutrients (protein; Nitrogen; Iron; Zinc; Copper). The results also reveal the presence of heavy metals (lead, cadmium) in concentrations above the WHO standards.Conclusion and implementation of the results: The results of phytochemical and nutritional analyzes confirmed the empirical uses identified in the ethnobotanical study. This plant is a remedy in the prevention and treatment of certain diseases, an excellent dietary supplement, and an alternative to chemical control. The presence of Trace of Elements Metals with concentrations higher than the WHO standards reflects a potential risk to human health. It is urgent for the central state, the social partners and the scientific community to rethink the production of Ocimum gratissimum Linn of acceptable phytosanitary quality in order to guarantee to the population the safe use of this Medicinal Plant with leafy vegetables, Health and Sustainable Development.Keywords: Ocimum gratissimum ; Leaf vegetable ; Medicinal plant ; Ethnobotany ; Cotonou ; Benin

Published
2017

13. Acceptability of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in Benin: a qualitative study.

Author

Ahouada, Carin, Diabaté, Souleymane, Gning, Ndeye Ndiagna, Hessou, Septime, Batona, Georges, Guédou, Fernand A., Béhanzin, Luc, Zannou, Marcel D., and Alary, Michel

Subjects
DIAGNOSIS of HIV infections, HIV prevention, HIV infection risk factors, FOCUS groups, HEALTH services accessibility, MEDICAL care costs, PREVENTIVE medicine, PATIENT safety, QUALITATIVE research, THEMATIC analysis, UNSAFE sex, HEALTH literacy, MEN who have sex with men, SEXUAL partners
Abstract

In Benin, consistent condom use among men who have sex with men (MSM) is relatively low and providing them with Pre-exposure prophylaxis (PrEP) could be of great relevance. We aimed to describe PrEP knowledge and intention to use it; identify key facilitators and barriers to PrEP; and describe the perceived impact of PrEP on unsafe sexual behavior. MSM, 18 years or older, HIV-negative or of unknown status, were enrolled in five cities of Benin. Intention to use PrEP was assessed through five focus groups (FG). Data were analyzed using manual thematic sorting. Thirty MSM (six per city) participated in the FG. Mean age (standard deviation) was 27.1 (5.0) years. All participants expressed the intention to use PrEP if made available. Facilitators of PrEP use were: availability of medication, safety, absence of constraints as well as freedom to have multiple sex partners and sex with HIV-positive friends. Barriers were: complex procedures for obtaining medication, size and taste of medication, cost of medication, poor PrEP awareness.. Eighteen men admitted that PrEP could lead to decrease in or even abandonment of condom use. In conclusion, MSM showed openness to use PrEP if available, although they recognized that it could lead to risk compensation. [ABSTRACT FROM AUTHOR]

Published
2020
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15. Evaluating the Determinants and Prevalence of HIV among Intravenous Drug Users in Benin

Author

Hessou, Septime, primary, Glèlè Ahanhanzo, Yolaine, additional, Yadouléton, Tranquillin, additional, T. Dougnon, Victorien, additional, Sodoloufo, Odile, additional, Drisdelle, Rhéal, additional, Bachabi, Moussa, additional, Ahoussinou, Clément, additional, Gnahoui-David, Bernard, additional, Magalie, Nelson, additional, Yaméogo, Bernabé, additional, R. Johnson, Christian, additional, and Djimon Zannou, Marcel, additional

Published
2018
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16. Biological Markers of Musculoskeletal Pain: A Scoping Review.

Author

Djade CD, Diorio C, Laurin D, Hessou SPH, Toi AK, Gogovor A, Sidibe A, Ekanmian G, Porgo TV, Zomahoun HTV, and Dionne CE

Abstract

Background: Musculoskeletal pain (MSP) is the leading contributor to disability, limiting mobility and dexterity. As research on the determinants of MSP is evolving, biomarkers can probably play a significant role in understanding its causes and improving its clinical management. This scoping review aimed to provide an overview of the associations between biomarkers and MSP., Methods: This study followed Arksey and O'Malley and PRISMA-ScR recommendations. Keywords related to biomarkers, association, and MSP were searched on PubMed, Embase, Cochrane, and Web of Science databases from inception to September 28th, 2023. Data were systematically retrieved from the retained articles. A narrative synthesis approach - but no quality assessment - was used to map the core themes of biological markers of MSP that emerged from this work., Results: In total, 81 out of 25,165 identified articles were included in this scoping review. These studies were heterogeneous in many aspects. Overall, vitamin D deficiency, dyslipidemia (or hypercholesterolemia), and cytokines (high levels) were the most studied biomarkers with regards to MSP and were most often reported to be associated with non-specific MSP. Cadmium, calcium, C-reactive protein, collagen, creatinine, hormones, omega-3 fatty acids, sodium, tumor necrosis factor-alpha, and vitamin C were also reported to be associated with MSP syndromes, but the evidence on these associations was sketchier. No conclusions could be drawn as to age and sex., Conclusions: Our findings suggest that some biomarkers are associated with specific MSP syndromes, while others would be associated with non-specific syndromes. Among all candidate markers, the evidence seems to be more consistent for vitamin D, cytokines and lipids (total cholesterol, triglycerides, low- and high-density lipoproteins). High-quality studies, stratified by age and sex, are needed to advance our understanding on biomarkers of MSP., Competing Interests: All authors declare that they have no conflicts of interest to report in this work., (© 2024 Djade et al.)

Published
2024
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