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2,320 results on '"Hicks, John"'

19. Creating a content delivery network for general science on the internet backbone using XCaches

Author

Fajardo, Edgar, Zvada, Marian, Weitzel, Derek, Rynge, Mats, Hicks, John, Selmeci, Mat, Lin, Brian, Paschos, Pascal, Bockelman, Brian, Sfiligoi, Igor, Hanushevsky, Andrew, and Würthwein, Frank

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

A general problem faced by computing on the grid for opportunistic users is that delivering cycles is simpler than delivering data to those cycles. In this project we show how we integrated XRootD caches placed on the internet backbone to implement a content delivery network for general science workflows. We will show that for some workflows on different science domains like high energy physics, gravitational waves, and others the combination of data reuse from the workflows together with the use of caches increases CPU efficiency while decreasing network bandwidth use.

Published
2020
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21. The constitution of the Northwest States

Author

Hicks, John D. and Hicks, John D.

Subjects
Constitutions Northwest, Pacific., Constitutional conventions Montana., Constitutions., Pacific Northwest.
Published
2024

26. Initiation of metformin in early pregnancy results in fetal bioaccumulation, growth restriction, and renal dysmorphology in a primate model

Author

Bolte, Erin, Dean, Tyler, Garcia, Brandon, Seferovic, Maxim D., Sauter, Kristin, Hummel, Gwendolynn, Bucher, Matthew, Li, Feng, Hicks, John, Qin, Xuan, Suter, Melissa A., Barrozo, Enrico R., Jochum, Michael, Shope, Cynthia, Friedman, Jacob E., Gannon, Maureen, Wesolowski, Stephanie R., McCurdy, Carrie E., Kievit, Paul, and Aagaard, Kjersti M.

Published
2024
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28. MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma

Author

Tao, Ling, Mohammad, Mahmoud A., Milazzo, Giorgio, Moreno-Smith, Myrthala, Patel, Tajhal D., Zorman, Barry, Badachhape, Andrew, Hernandez, Blanca E., Wolf, Amber B., Zeng, Zihua, Foster, Jennifer H., Aloisi, Sara, Sumazin, Pavel, Zu, Youli, Hicks, John, Ghaghada, Ketan B., Putluri, Nagireddy, Perini, Giovanni, Coarfa, Cristian, and Barbieri, Eveline

Published
2022
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30. Initiation of Metformin in Early Pregnancy Results in Fetal Bioaccumulation, Growth Restriction & Renal Dysmorphology in a Primate Model

Author

BOLTE, Erin, primary, DEAN, Tyler, additional, GARCIA, Brandon, additional, SEFEROVIC, Maxim D., additional, SAUTER, Kristin, additional, HUMMEL, Gwendolynn, additional, BUCHER, Matthew, additional, Li, Feng, additional, HICKS, John, additional, QIN, Xuan, additional, SUTER, Melissa A., additional, BARROZO, Enrico R., additional, JOCHUM, Michael, additional, SHOPE, Cynthia, additional, FRIEDMAN, Jacob E., additional, GANNON, Maureen, additional, WESOLOWSKI, Stephanie R., additional, MCCURDY, Carrie E., additional, KIEVIT, Paul, additional, and AAGAARD, Kjersti M., additional

Published
2024
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34. FERMENTATION PEN PALS

Author

Hicks, John

Subjects
Fermentation, General interest, Home and garden, Hobbies and crafts
Abstract

I'm looking for people who've mastered the process of making probiotic and fermentation foods, such as sauerkraut and Korean kimchi. traditionally from scratch. John Hicks 5012 Highway 67E Hope, AR [...]

Published
2024

40. Corrigendum to “A Comparative Study on Antimicrobial Resistance in Escherichia coli Isolated from Channel Catfish and Related Freshwater Fish Species” [J. Food Protect. 87(1) (2023) 100192]

Author

Soku, Yesutor K., primary, Mohamed, Abdelrahman, additional, Samuel, Temesgen, additional, Dessai, Uday, additional, Walls, Isabel, additional, Rockwell, Catherine, additional, Fortenberry, Gamola, additional, Berutti, Tracy, additional, Nieves-Miranda, Sharon, additional, Nawrocki, Erin M., additional, Fu, Yezhi, additional, Dudley, Edward, additional, Mamber, Stephen W., additional, and Hicks, John, additional

Published
2024
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41. 25 Initiation of Metformin in Pregnancy Results in Fetal Bioaccumulation, Growth Restriction & Renal Dysmorphology

Author

Aagaard, Kjersti M., primary, Kievit, Paul, additional, Gannon, Maureen, additional, McCurdy, Carrie, additional, Wesolowski, Stephanie, additional, Friedman, Jed, additional, Dean, Tyler, additional, Sauter, Kristin, additional, Seferovic, Maxim D., additional, Garcia, Brandon T., additional, Li, Feng, additional, Hicks, John, additional, Qin, Xuan, additional, Bolte, Erin, additional, Hummel, Gwendolynn, additional, and Suter, Melissa, additional

Published
2024
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43. Familiar Technology Promotes Academic Success for Students with Exceptional Learning Needs

Author

Wilson, Carolyn H., Brice, Costeena, Carter, Emanuel I., Fleming, Jeffery C., Hay, Dontia D., Hicks, John D., Picot, Ebony, Taylor, Aashja M., and Weaver, Jessica

Abstract

Children with exceptional learning needs find it very difficult to retain content information from the regular curriculum. Many content teachers also find it difficult to adapt curriculum to the learning needs of these exception children within the confines of the classroom and without any assistance. Although many schools are equipped with technology assisted instruction; it is not being used either because of the ineptibility of the classroom teacher to incorporate the technology into the lesson objective or because of the lack of time it would take to plan how to incorporate learning technology in today's classroom. This research deals with how to take modern day technology that students with exceptional needs are familiar with and incorporate that technology into the classroom setting. The Office of Special Education Programs (2011) has reported that the use of popular technology that children with exceptional learning needs are familiar with can be incorporated in classroom instruction and beyond. A bibliography is included.

Published
2011

44. Robert Maynard Hutchins : A Memoir

Author

MAYER, MILTON, Hicks, John H., Edited by, Terkel, Studs, Foreword by, MAYER, MILTON, Hicks, John H., and Terkel, Studs

Published
2023

45. COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

Author

Watkin, Levi B, Jessen, Birthe, Wiszniewski, Wojciech, Vece, Timothy J, Jan, Max, Sha, Youbao, Thamsen, Maike, Santos-Cortez, Regie LP, Lee, Kwanghyuk, Gambin, Tomasz, Forbes, Lisa R, Law, Christopher S, Stray-Pedersen, Asbjørg, Cheng, Mickie H, Mace, Emily M, Anderson, Mark S, Liu, Dongfang, Tang, Ling Fung, Nicholas, Sarah K, Nahmod, Karen, Makedonas, George, Canter, Debra L, Kwok, Pui-Yan, Hicks, John, Jones, Kirk D, Penney, Samantha, Jhangiani, Shalini N, Rosenblum, Michael D, Dell, Sharon D, Waterfield, Michael R, Papa, Feroz R, Muzny, Donna M, Zaitlen, Noah, Leal, Suzanne M, Gonzaga-Jauregui, Claudia, Boerwinkle, Eric, Eissa, N Tony, Gibbs, Richard A, Lupski, James R, Orange, Jordan S, and Shum, Anthony K

Subjects
Biochemistry and Cell Biology, Biological Sciences, Autoimmune Disease, Lung, Arthritis, Genetics, 2.1 Biological and endogenous factors, Aetiology, Inflammatory and immune system, Amino Acid Sequence, Autoimmune Diseases, Child, Preschool, Coatomer Protein, Endoplasmic Reticulum, Endoplasmic Reticulum Stress, Female, Genetic Association Studies, Genetic Predisposition to Disease, Golgi Apparatus, HEK293 Cells, Humans, Infant, Lod Score, Lung Diseases, Interstitial, Male, Molecular Sequence Data, Pedigree, Protein Transport, Baylor-Hopkins Center for Mendelian Genomics, Medical and Health Sciences, Developmental Biology, Agricultural biotechnology, Bioinformatics and computational biology
Abstract

Unbiased genetic studies have uncovered surprising molecular mechanisms in human cellular immunity and autoimmunity. We performed whole-exome sequencing and targeted sequencing in five families with an apparent mendelian syndrome of autoimmunity characterized by high-titer autoantibodies, inflammatory arthritis and interstitial lung disease. We identified four unique deleterious variants in the COPA gene (encoding coatomer subunit α) affecting the same functional domain. Hypothesizing that mutant COPA leads to defective intracellular transport via coat protein complex I (COPI), we show that COPA variants impair binding to proteins targeted for retrograde Golgi-to-ER transport. Additionally, expression of mutant COPA results in ER stress and the upregulation of cytokines priming for a T helper type 17 (TH17) response. Patient-derived CD4(+) T cells also demonstrate significant skewing toward a TH17 phenotype that is implicated in autoimmunity. Our findings uncover an unexpected molecular link between a vesicular transport protein and a syndrome of autoimmunity manifested by lung and joint disease.

Published
2015

46. Residual manifestations of hypercortisolemia following surgical treatment in a patient with Cushing syndrome.

Author

Bartz, Sara, Karaviti, Lefkothea, Brandt, Mary, Lopez, Monica, Masand, Prakash, Devaraj, Sridevi, Hicks, John, Anderson, Lauren, Lodish, Maya, Keil, Meg, and Stratakis, Constantine

Subjects
Cushing syndrome, Obesity, PPNAD, Primary pigmented nodular adrenocortical disease
Abstract

CONTEXT: Cushing Syndrome is difficult to diagnose, and the comorbidities and persistent late effects of hypercortisolemia after treatment of the primary disease are challenging for the patient and the endocrinologist. OBJECTIVE: To report the case of a girl with obesity and hypertension, ultimately diagnosed with Cushing syndrome due to primary pigmented nodular adrenocortical disease. In this case, the complications of hypercortisolism persisted short term despite surgical intervention. PATIENT: A 4 year old morbidly obese African-American girl with developmental delay presented with hypertensive emergency in the ER and 18-month history of progressive weight gain. Her previous history included premature adrenarche, hypertension, seizures and a random high cortisol with suppressed ACTH. She was subsequently stabilized, and a diagnostic work-up persistently demonstrated elevated cortisol and suppressed ACTH. An abdominal MRI showed bilateral adrenal multinodular disease, consistent with multinodular hyperplasia of the adrenal glands. Based on these findings the patient underwent a bilateral adrenalectomy, which confirmed primary pigmented nodular adrenocortical disease. The patient had a complicated, protracted post-operative course requiring adjustment of therapy for persistent hypertension. Two months after surgery, she was readmitted to the Emergency Department with hyperpyrexia and hypertension and succumbed to the complications of sepsis. CONCLUSIONS AND OUTCOME: This case highlights the significant diagnostic and therapeutic challenges in treating children with Cushing syndrome. Resolution of the source of hypercortisolemia does not imply regression of hypertension or recovery of the immune system. Although the child underwent bilateral adrenalectomy, persistent consequences of prolonged severe hypercortisolism contributed to her death two months later.

Published
2015

47. Predicting Stimulus-Driven Attentional Selection Within Mobile Interfaces

Author

Still, Jeremiah D., Hicks, John, Cain, Ashley, Billman, Dorrit, Kacprzyk, Janusz, Series editor, Pal, Nikhil R., Advisory editor, Bello Perez, Rafael, Advisory editor, Corchado, Emilio S., Advisory editor, Hagras, Hani, Advisory editor, Kóczy, László T., Advisory editor, Kreinovich, Vladik, Advisory editor, Lin, Chin-Teng, Advisory editor, Lu, Jie, Advisory editor, Melin, Patricia, Advisory editor, Nedjah, Nadia, Advisory editor, Nguyen, Ngoc Thanh, Advisory editor, Wang, Jun, Advisory editor, and Baldwin, Carryl, editor

Published
2018
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48. Restoration of the molecular clock is tumor suppressive in neuroblastoma

Author

Moreno-Smith, Myrthala, Milazzo, Giorgio, Tao, Ling, Fekry, Baharan, Zhu, Bokai, Mohammad, Mahmoud A., Di Giacomo, Simone, Borkar, Roshan, Reddy, Karthik Reddy Kami, Capasso, Mario, Vasudevan, Sanjeev A., Sumazin, Pavel, Hicks, John, Putluri, Nagireddy, Perini, Giovanni, Eckel-Mahan, Kristin, Burris, Thomas P., and Barbieri, Eveline

Published
2021
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