1. 70 μm diameter optical probe for common-path optical coherence tomography in air and liquids
- Author
-
Marica Marrese, Davide Iannuzzi, Hidde Offerhaus, Erik Paardekam, Biophotonics and Medical Imaging, LaserLaB - Biophotonics and Microscopy, and Amsterdam Neuroscience - Brain Imaging
- Subjects
Materials science ,genetic structures ,02 engineering and technology ,01 natural sciences ,010309 optics ,chemistry.chemical_compound ,Optics ,Optical coherence tomography ,0103 physical sciences ,medicine ,Fiber ,medicine.diagnostic_test ,business.industry ,High-refractive-index polymer ,021001 nanoscience & nanotechnology ,Atomic and Molecular Physics, and Optics ,Common path ,chemistry ,Barium titanate ,sense organs ,0210 nano-technology ,business ,SDG 6 - Clean Water and Sanitation ,Sensitivity (electronics) ,Refractive index ,Preclinical imaging - Abstract
We investigate and validate a novel method to fabricate ultrathin optical probes for common-path optical coherence tomography (CP-OCT). The probes are obtained using a 65 μm barium titanate microsphere inserted into an inward concave cone chemically etched at the end of a single-mode fiber. We demonstrate that the high refractive index (n 1.95) of the barium titanate microspheres allows one to maintain high sensitivity even while imaging in liquids, reaching a sensitivity of 83 dB. Due to its low cost, flexibility, and ease of use, the probe holds promise for the development of a new generation of ultrathin needle-based OCT systems.
- Published
- 2018