170 results on '"Higashi, Yasuyuki"'
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2. Impacts of dosing and drug withdrawal period on tacrolimus-based triple therapy in a non-human primate renal transplantation model
3. The Effects of Endoplasmic Reticulum Stress via Intratracheal Instillation of Water-Soluble Acrylic Acid Polymer on the Lungs of Rats.
4. Difficulty differentiating primary mediastinal classical Hodgkin lymphoma from inflammatory myofibroblastic tumor: A case report.
5. Discovery of tricyclic dipyrrolopyridine derivatives as novel JAK inhibitors
6. A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model
7. A rare case of double primary lung adenocarcinomas with uncommon complex EGFR G719X and S768I mutations and pleomorphic carcinoma.
8. Crosslinked Structure of Polyacrylic Acid Affects Pulmonary Fibrogenicity in Rats
9. Release mechanisms of tacrolimus-loaded PLGA and PLA microspheres and immunosuppressive effects of the microspheres in a rat heart transplantation model
10. Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3
11. Discovery of 3,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2(1H)-one derivatives as novel JAK inhibitors
12. Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation
13. Pulmonary disorder induced by cross‐linked polyacrylic acid
14. Waterproof spray‐induced lung injury while using a heater
15. Inhibition of c-Rel DNA binding is critical for the anti-inflammatory effects of novel PIKfyve inhibitor
16. ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution
17. Effect of novel PKCΘ selective inhibitor AS2521780 on acute rejection in rat and non-human primate models of transplantation
18. Effect of AS2521780, a novel PKCΘ selective inhibitor, on T cell-mediated immunity
19. Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib
20. Efficacy of Oral Treatment With Tacrolimus in the Renal Transplant Model in Cynomolgus Monkeys
21. Anti-inflammatory effect and selectivity profile of AS1940477, a novel and potent p38 mitogen-activated protein kinase inhibitor
22. Transplanting stem cells: Potential targets for immune attack. Modulating the immune response against embryonic stem cell transplantation
23. Hepatitis C virus genotypes are not responsible for development of serious liver disease
24. NOVEL ANTAGONISTIC ANTI-CD28 mAb WITH SILENT Fc IS SUPERIOR TO CONVENTIONAL (AGONISTIC) ANTI-CD28 mAb FOR PREVENTION OF CARDIAC ALLOGRAFT REJECTION: OR-052
25. FK1706, a novel non-immunosuppressive immunophilin: neurotrophic activity and mechanism of action
26. Evaluation of the Influence of the Experience and Training of EBUS-TBNA on Diagnostic Rate and Safety
27. A Case of Left Upper Lobe Lung Cancer Successfully Diagnosed by Transesophageal Endoscopic Ultrasound with Bronchoscope-Guided Fine Needle Aspiration Alone
28. Benefits of a loading dose of tacrolimus on graft survival of kidney transplants in nonhuman primates
29. Effective suppression of donor specific antibody production by Cathepsin S inhibitors in a mouse transplantation model
30. Deficiency of antibody response to hypervariable region of hepatitis C virus in patients with chronic hepatitis C
31. FK506 suppresses neutrophil chemoattractant production by peripheral blood mononuclear cells
32. Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
33. The Effect of ASP2409, a Novel CD86-Selective Variant of CTLA4-Ig, on Renal Allograft Rejection in Nonhuman Primates
34. Immunosuppressive effect of ASP2408, a novel CD86-selective variant of CTLA4-Ig, in rats and cynomolgus monkeys
35. Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
36. A chronic renal rejection model with a fully MHC-mismatched rat strain combination under immunosuppressive therapy
37. Synthesis and Evaluation of 1H-Pyrrolo[2,3-b]pyridine Derivatives as Novel Immunomodulators Targeting Janus Kinase 3
38. JAK inhibitors as a new generation of small-molecule immunosuppressants
39. Effect of recombinant human transforming growth factor β1 on immune responses in patients with chronic hepatitis B
40. A Comparison of Protocols Used to Generate Insulin-Producing Cell Clusters from Mouse Embryonic Stem Cells
41. Topical Application of FK506 (Tacrolimus) Ointment Inhibits Mite Antigen-Induced Dermatitis by Local Action in NC/Nga Mice
42. Tacrolimus suppressed the production of cytokines involved in atopic dermatitis by direct stimulation of human PBMC system. (Comparison with steroids)
43. Atopic Dermatitis-Like Skin Lesions Induced by Topical Application of Mite Antigens in NC/Nga Mice
44. Role of Inhibition of Penicillin Binding Proteins and Cell Wall Cross-Linking by Beta-Lactam Antibiotics in Low- and High-Level Methicillin Resistance of Staphylococcus aureus
45. Biochemical and pharmacological characterization of FK706, a novel elastase inhibitor
46. Predictive factors in the response to interferon therapy in chronic hepatitis C
47. Dynamics of Genome Change in the E2/NS1 Region of Hepatitis C Virus in Vivo
48. Comparison of Envelope and Precore/Core Variants of Hepatitis B Virus (HBV) during Chronic HBV Infection
49. Long-term carriage of hepatitis C virus with normal aminotransferase after interferon treatment in patients with chronic hepatitis C
50. A pilot study of ribavirin and interferon beta for the treatment of chronic hepatitis C
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