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2. Abstracts of selected papers presented at the 31st annual meeting of the Japanese Society of Gastroenterology October 5–7, 1989, Asahikawa, Japan

Author

Yagi, Kinji, Sugaya, Eiichi, Fusamoto, Hidcyuki, Kamada, Takenobu, Nakamura, Masahiko, Oda, Masaya, Uehara, Akira, Namiki, Masayoshi, Itoh, Kazuro, Matsuo, Yutaka, Yoshikawa, Toshikazu, Suematsu, Makoto, Kurose, Iwao, Sekiya, Chihiro, Kohda, Hironobu, Narumi, Shunji, Takahashi, Ken-ichi, Sasaki, Mutsuo, Ono, Keiichi, Manabe, Tadao, Ohshio, Gakuji, Iishi, Hiroyasu, Tatsuta, Masaharu, Fuchigami, Tadahiko, Iwashita, Akinori, Sekoguchi, Tsutomu, Inamori, Shigeharu, Ajioka, Yoichi, Watanabe, Hidenobu, Masaki, Tadahiko, Suzuki, Kimitaka, Shimamoto, Chikao, Hirata, Ichiro, Hinoda, Yuji, Yachi, Akira, Kijima, Hiroshi, Watanabe, Hidenobu, Yamao, Kenji, Nakazawa, Saburo, Wada, Yoshiyuki, Semba, Daisuke, Saito, Akiko, Obata, Hiroshi, Tarao, Kazuo, Shimizu, Akio, Hirohashi, Setsuo, Fujiyama, Shigetoshi, Izuno, Kiyonori, Matsui, Osamu, Kadoya, Masumi, Fukuda, Morimichi, Mima, Satoaki, Oi, Hiromichi, Nakamura, Hironobu, Itani, Kenji, Yoshikawa, Toshikazu, Ebara, Masaaki, Ohto, Masao, Takasaki, Ken, Aruga, Atsushi, Okuda, Koji, Nakayama, Toshimichi, Arii, Shigcki, Tobe, Takayoshi, Nonami, Toshiaki, Takagi, Hiroshi, Mayumi, Toshihiko, Hachisuka, Kitao, Aoike, Akira, Nakamura, Keiya, Nagahata, Yoshi, Saitoh, Yoichi, Iwasaki, Ariyoshi, Aizawa, Toshiharu, Sato, Nobuhiro, Kawano, Sunao, Shibata, Yoshimi, Okamura, Kiyoshi, Hori, Shinji, Yamamura, Makoto, Akimoto, Shin, Igarashi, Tatsuki, Takase, Kojiro, Tameda, Yukihiko, Nakajima, Yasuaki, Uchino, Junichi, Noro, Toshio, Yamashiro, Moriya, Miyake, Hirofumi, Matsumoto, Shuji, Higashiguchi, Takashi, Ogura, Yoshifumi, Hayashi, Hiroto, Suzuki, Takashi, Higashiguchi, Takashi, Ogura, Yoshifumi, Hayashi, Hiroto, Suzuki, Takashi, Kumashiro, Ryukichi, Tanikawa, Kyuichi, Adachi, Yukihiko, Yamamoto, Toshio, Izawa, Kunihide, Tsuchiya, Ryoichi, Inui, Kazuo, Nakazawa, Saburo, Suyama, Masafumi, Ariyama, Jo, Nakasako, Toshiaki, Hanyu, Fujio, Imaizumi, Toshihide, Matsuda, Yoshiaki, Hasebe, Osamu, Noguchi, Takashi, Mizumoto, Ryuji, Matsueda, Kei, Umeda, Noritsugu, Hongo, Michio, Harasawa, Shigeru, Takayasu, Hiroyuki, Kusano, Motoyasu, Sekiguchi, Toshikazu, Okano, Hiroyuki, Saeki, Susumu, Shimada, Akira, Nakagawa, Tetsuya, Ozaki, Shoichi, Kobayashi, Kenzo, Fukudo, Shin, Suzuki, Jinichi, Sasaki, Daisuke, Kawasaki, Masatoshi, Kasai, Fukio, Takebe, Kazuo, Kobayashi, Masayoshi, Kawarada, Hiroaki, Ochiai, Takumi, Nagahama, Akira, Tsuji, Kagetoshi, Himeno, Seiichi, Toyosaka, Akihiro, and Okamoto, Eizo

Published
1991
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5. Abstracts of selected papers presented at the 29th annual meeting of the Japanese society of gastroenterology Kofu, Japan, November 5–7, 1987

Author

Imai, Yasuharu, Kiyosawa, Kendo, Sata, Michio, Tanikawa, Kyuichi, Hino, Keisuke, Konishi, Tomomi, Tajima, Heiichiro, Yano, Michitami, Kojima, Toyoo, Ichida, Fumihiro, Ito, Tetsuo, Watanabe, Shozo, Tozuka, Shinichi, Uchida, Toshikazu, Michitaka, Kojiro, Ohta, Yasuyuki, Matsuura, Kazuharu, Tsuji, Takao, Shibayama, Takao, Tanaka, Satoshi, Shimizu, Masaru, Kojima, Mineo, Akahane, Yoshihiro, Miyazaki, Yoshiki, Kurai, Kiyohiko, Uno, Shiro, Yokosuka, Osamu, Omata, Masao, Hayashi, Norio, Kamada, Takenobu, Mizokami, Masashi, Orito, Etsuro, Tokita, Hajime, Kametani, Masaaki, Suga, Mitsuo, Yokota, Katsuji, Saito, Yasuharu, Higuchi, Akihiko, Sasaki, Yutaka, Hayashi, Norio, Fujimoto, Kazuma, Sakata, Toshiie, Naruse, S., Takagi, T., Tangoku, Akira, Ozasa, Hiroaki, Chiba, Tsutomu, Yamada, Tadataka, Azuma, Takeshi, Nakajima, Chiharu, Tada, Masahiro, Kawano, Hirofumi, Takayama, Sumio, Aoki, Teruaki, Kusano, Motoyasu, Nishioka, Toshio, Sakamoto, Tsuguo, Miyata, Masahiko, Iishi, Hiroyasu, Tatsuta, Masaharu, Okuno, Masaru, Himeno, Seiichi, Kobayashi, Masayoshi, Goto, Yoshio, Masuzawa, Shigeyuki, Tsuchita, Shuji, Ueno, Takato, Tanikawa, Kyuichi, Fukuda, Yoshihide, Nagura, Hiroshi, Tanaka, Yousuke, Manabe, Tadao, Fujimura, Masaki, Sakamoto, Tuguo, Funakoshi, Akihiro, Miyazaki, Kazunori, Sumi, Shoichiro, Inoue, Kazutomo, Ohshima, Ikuya, Kouzu, Teruo, Hashimoto, Hiroshi, Mitsunaga, Atsushi, Yasuda, Kenjiro, Nakajima, Masatsugu, Aibe, Tsuyoshi, Noguchi, Takayoshi, Yamanaka, Toshihiro, Nakamura, Tsuneya, Saitoh, Norio, Sarashina, Hiromi, Endoh, Masaaki, Konn, Mitsuru, Morita, Keiichi, Kanoh, Junichi, Abe, Minoru, Narisawa, Rintaro, Yamanaka, Takeo, Kimura, Ken, Kimura, Osamu, Korenaga, Daisuke, Hirose, Kazuo, Yonemura, Yutaka, Yoshino, Hiroaki, Akiyama, Toshio, Nakamura, Masahiro, Makiyama, Takao, Kosaka, Takeo, Masaki, Tadahiko, Omata, Kosaku, Une, Yoshie, Imai, Takazumi, Kagawa, Keizo, Hino, Akitsugu, Tarao, Kazuo, Kusano, Mitsuo, Tsugita, Masashi, Takahashi, Yutaka, Sujino, Hajime, and Tomino, Yoshiro

Published
1988
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10. Activation of the β-catenin gene by interstitial deletions involving exon 3 as an early event in colorectal tumorigenesis

Author

Murata, Masaru, primary, Iwao, Kyoko, additional, Miyoshi, Yasuo, additional, Nagasawa, Yutaka, additional, Yabu, Michihiro, additional, Himeno, Seiichi, additional, Imanishi, Kiyoshi, additional, Ohsawa, Masahiko, additional, Wada, Hisashi, additional, Tominaga, Shusei, additional, Shimano, Takashi, additional, Kobayashi, Tetsuro, additional, and Nakamura, Yusuke, additional

Published
2000
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14. Follow-up after the Hanshin-Awaji Earthquake: Diverse Influences on Pneumonia, Bronchial Asthma, Peptic Ulcer and Diabetes Mellitus.

Author

TAKAKURA, Rena, primary, HIMENO, Seiichi, additional, KANAYAMA, Yoshio, additional, SONODA, Takashi, additional, KIRIYAMA, Kazuo, additional, FURUBAYASHI, Takayasu, additional, YABU, Michihiro, additional, YOSHIDA, Shingo, additional, NAGASAWA, Yutaka, additional, INOUE, Shinya, additional, and IWAO, Norihito, additional

Published
1997
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15. Efficacy of combination therapy of interferon-? with ursodeoxycholic acid in chronic hepatitis C: A randomized controlled clinical trial

Author

Kiso, Shinichi, primary, Kawata, Sumio, additional, Tamura, Shinji, additional, Imai, Yasuharu, additional, Inui, Yoshiaki, additional, Nagase, Toshihiko, additional, Maeda, Yuichi, additional, Yamasaki, Eiji, additional, Tsushima, Hirofumi, additional, Igura, Takumi, additional, Himeno, Seiichi, additional, Seki, Kouichi, additional, and Matsuzawa, Yuji, additional

Published
1997
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16. Multicenter trial of 24 weeks' alpha interferon therapy for chronic hepatitis C. Comparison between two different administration schedules.

Author

OKUNO, Tadao, primary, HIGASHINO, Kazuya, additional, IMOTO, Tsutomu, additional, OHOKA, Teruji, additional, OKUSHIN, Hiroaki, additional, KASUGA, Masato, additional, KAWARA, Akira, additional, SHINJI, Yoshitake, additional, SEKI, Kouichi, additional, CHIBA, Tsutomu, additional, TOUDOU, Akio, additional, YAMAWAKI, Mikio, additional, HADA, Hisaichi, additional, HIMENO, Seiichi, additional, FUKUMA, Kanzo, additional, and YUU, Housai, additional

Published
1995
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20. Gastric Ulcer Formation after the Hanshin-Awaji Earthquake: A Case Study of Helicobacter pylori Infection and Stress-Induced Gastric Ulcers.

Author

Matsushima, Yumi, Aoyama, Nobuo, Fukuda, Haruhiko, Kinoshita, Yoshikazu, Todo, Akio, Himeno, Seiichi, Fujimoto, Sotaro, Kasuga, Masato, Nakase, Hiroshi, and Chiba, Tsutomu

Subjects
GASTRIC disease diagnosis, HELICOBACTER pylori
Abstract

Background. Both Helicobacter pylori (H. pylori) infection and various stresses are known to induce peptic ulcer disease of the upper gastrointestinal tract. However, the pathogenetic relationship between the two factors has not yet been clarified. We conducted a case-control study to examine whether H. pylori infection played a role in the development of gastric ulcer (GU) induced by life-event stresses that were experienced after the Hanshin-Awaji earthquake. Materials and Methods. Serum samples from patients in the devastated area who developed GUs during the 2 months following the Hanshin-Awaji earthquake and those from GU patients in the same area during the corresponding period of the previous year, and from gender-, age- and institute-matched ulcer-free controls were tested for the presence of the H. pylori IgG antibody. Results. A significant association between H. pylori infection and the development of GU in uninjured patients was observed in all sets [matched odds ratio (OR) = 3.23, 95% confidence interval: 1.95–5.35]. Moreover, the prevalence of H. pylori infection in patients who developed GUs after the earthquake was not different from that for GU patients in the previous year. In contrast, there was no association between H. pylori infection and the development of GU in the physically injured patients after the earthquake. Conclusions. H. pylori infection may play an important role in the development of GUs that are induced by emotional life-event stresses. [ABSTRACT FROM AUTHOR]

Published
1999
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22. Temporal Profiles of Urinary Excretion of NH2-Terminal Big Gastrin Immunoreactivity in Humans.

Author

Nagao, Kazuhiro, Higashimoto, Yoshifumi, Shinomura, Yasuhisa, Himeno, Seiichi, Miyazaki, Yoshiji, Yasunaga, Yuuichi, and Tarui, Seiichiro

Subjects
GASTRIN, GASTROINTESTINAL hormones, GASTRIC secretions, TOTAL parenteral feeding, ARTIFICIAL feeding
Abstract

We studied the temporal profile of urinary NH2-terminal big gastrin immunoreactivity (NT G-34-IR) excretion in order to evaluate the dynamics of gastrin secretion. The temporal profile of urinary NT G-34-IR excretion in normal subjects represented three peaks corresponding to each meal. In contrast, the profile in antrectomized patients and patients under total parenteral nutrition (TPN) represented a fiat pattern. Urinary NT G-34-IR excretions during fasting 2-h periods in antrectomized patients and TPN patients were about one-sixth and one-third, respectively, of basal NT G-34- IR excretion in normal subjects (53.1 ± 13.9 pmol/ h). Total urinary NT G-34-IR excretion during 24 h both in antrectomized patients (220 ± 35 pmol/24 h) and TPN patients (390 ± 68 pmol/24 h) was also significantly lower than in normal subjects (1985 ± 403 pmol/24 h). The present study showed that the main source of urinary NT G-34-IR is the gastric antrum, that the main factor fluctuating its excretion is food intake, and that long-term TPN reduces basal gastrin secretion. Urinary NT G-34-IR would be a useful indicator for total gastrin secretion. [ABSTRACT FROM AUTHOR]

Published
1990

23. A Possible Indicator of Urinary NH2-Terminal Big Gastrin Immunoreactivity for Gastrin Secretion.

Author

Higashimoto, Yoshifumi, Himeno, Seiichi, Shinomura, Yasuhisa, Kuroshima, Toshio, Nagao, Kazuhiro, and Tarui, Seiichiro

Subjects
GASTRIN, RADIOIMMUNOASSAY, IMMUNE serums, PEPTIDES, URINE
Abstract

Urinary and plasma gastrin immunoreactivities in normal subjects were studied by radioimmunoassays using three region-specific antisera. Urinary excretion of NH2-terminal big gastrin immunoreactivity (NT G-34-IR) in the fasting state (0.79 ± 0.17 pmol/kg/h, mean ± SE) was several hundred times as much as that of either COOH-terminal gastrin or gastrin/cholecystokinin immunoreactivity. Urinary NT G-34-IR increased significantly after feeding, and correlated closely with integrated plasma NT G-34-IR. Renal clearance of NT G-34-1R was 62.4 ± 7.9 ml/min and about one hundred times greater than that of any other gastrin immunoreactivities, indicating that there exist different catabolic pathways of gastrin peptides in the kidney. Gel filtration of urine extract revealed that a single giant peak of NT G-34-IR eluted in a later position than NH2-terminal heptadecapeptide of big gastrin. These results suggest that most of plasma NT G-34-IR is excreted in urine, and urinary excretion of NT G-34-IR reflects well-integrated plasma NT G-34-IR. Therefore, urinary NT G-34-IR may serve as a feasible indicator for gastrin secretion. [ABSTRACT FROM AUTHOR]

Published
1990

24. Marked Prolongation in Disappearance Half-Time of Plasma Cholecystokinin-Octapeptide in Patients with Hepatic Cirrhosis.

Author

Kanayama, Shuji, Himeno, Seiichi, Kurokawa, Masanori, Shinomura, Yasuhisa, Kuroshima, Toshio, Okuno, Masaru, Tsuji, Kagetoshi, Higashimoto, Yoshifumi, Ikei, Nobuhiro, Hashimura, Etsuro, Tateishi, Kayoko, Hamaoka, Toshiyuki, and Tarui, Seiichiro

Subjects
CHOLECYSTOKININ, GASTROINTESTINAL hormones, PEPTIDES, CIRRHOSIS of the liver, LIVER diseases, RADIOIMMUNOASSAY
Abstract

For exploration on the elimination of cholecystokinin from the circulation, the disappearance half-time of cholecystokinin-octapeptide was estimated with cholecystokinin specific radioimmunoassay in normal subjects and patients with chronic renal failure and with hepatic cirrhosis. With a brief infusion of 30.4 ng/kg of cholecystokinin-octapeptide for 2 min, plasma cholecystokinin level rose from 16.1 ± 3.6 pg/ml (mean ± SE) to 216.5 ± 6.1 pg/ml at 3 min after starting infusion, and decreased rapidly in a single exponential fashion for 10 min in hepatic cirrhosis. The disappearance half-time of cholecystokinin-octapeptide in patients with hepatic cirrhosis was 2.45 ± 0.07 min, and it was significantly longer than that in normal subjects (1.30 ± 0.07) or patients with chronic renal failure (1.70 ± 0.11). These findings suggest that the liver plays a major role in cholecystokinin-octapeptide elimination in humans. [ABSTRACT FROM AUTHOR]

Published
1985

25. Effect of Intraduodenal Load of Endogenous Acid on Secretin Release in Patients with Peptic Ulcer.

Author

Kurokawa, Masanori, Saito, Ryotaro, Shinomura, Yasuhisa, Takahashi, Shuichi, Hamabe, Sunao, Himeno, Seiichi, Shima, Kenji, and Tarui, Seiichiro

Subjects
PEPTIC ulcer, DUODENAL ulcers, SECRETIN, GASTRIC juice, GASTROINTESTINAL hormones
Abstract

In order to explore secretory mechanisms in peptic ulcer, the plasma secretin response to an intraduodenal load of gastric acid stimulated with tetragastrin was studied in 10 patients with duodenal ulcer, nine with gastric ulcer, and five young healthy volunteers. After the injection of tetragastrin plasma secretin level was significantly increased in all subjects. The integrated incremental secretin output significantly correlated with the incremental acid output in the duodenal ulcer group as well as the gastric ulcer group. There was no significant difference in the integrated incremental secretin output among the three groups. However, the integrated incremental secretin output per unit amount of gastric acid loaded in the duodenum was significantly lower in the duodenal ulcer group than in the other two groups. These results suggest that in patients with duodenal ulcer the secretin release in response to an intraduodenal load of endogenous acid is impaired. [ABSTRACT FROM AUTHOR]

Published
1982

26. Two cases of chronic idiopathic intestinal pseudoobstruction with abnormal esophageal motility and bilateral hydronephrosis.

Author

TSUJI, Kagetoshi, primary, HIMENO, Seiichi, additional, KUROSHIMA, Toshio, additional, OKUNO, Masaru, additional, KAWAMOTO, Hiroji, additional, HIGAAHIMOTO, Yoshifumi, additional, KASHIMYRA, Masanori, additional, YAMAZAKI, Yuichiro, additional, TARUI, Seiichiro, additional, KANAYAMA, Shuji, additional, and KUROKAWA, Masanori, additional

Published
1988
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37. 71 FAMILY STUDY OF HEREDITARY XANTHINURIA -DECREASED DUODENAL XANTHINE OXIDASE ACTIVITY AND INCREASED URINARY EXCRETION OF XANTHINE AND HYPOXANTHINE IN HETEROZYGOTES

Author

Kawachi, Masanori, primary, Kono, Norio, additional, Mineo, Ikuo, additional, Hara, Naoko, additional, Himeno, Seiichi, additional, Yamada, Yuya, additional, Kiyokawa, Hiroaki, additional, Yamasaki, Tomoyuki, additional, Wang, Yan Lin, additional, Kuwajima, Masamichi, additional, and Tarui, Seiichiro, additional

Published
1988
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40. Forskolin-induced cyclic AMP production and gastric acid secretion in dispersed rabbit parietal cells: Novel evidence for a major role of cyclic AMP in acid release

Author

Takahashi, Shuichi, primary, Moriwaki, Kaname, additional, Himeno, Seiichi, additional, Kuroshima, Toshio, additional, Shinomura, Yasuhisa, additional, Hamabe, Sunao, additional, Kurokawa, Masanori, additional, Saito, Ryotaro, additional, Kitani, Teruo, additional, and Tarui, Seiichiro, additional

Published
1983
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44. 71

Author

Kawachi, Masanori, Kono, Norio, Mineo, Ikuo, Hara, Naoko, Himeno, Seiichi, Yamada, Yuya, Kiyokawa, Hiroaki, Yamasaki, Tomoyuki, Wang, Yan Lin, Kuwajima, Masamichi, and Tarui, Seiichiro

Published
1988

45. [A case of sclerosing cholangitis trigered by 5-FU/leucovorine combination therapy and rapidly deteriorated].

Author

Nishimoto T, Kiriyama K, Yabu M, Kato T, Yamamoto S, and Himeno S

Subjects
Aged, Cholangitis, Sclerosing drug therapy, Cholangitis, Sclerosing etiology, Colonic Neoplasms pathology, Colonic Neoplasms surgery, Combined Modality Therapy, Fatal Outcome, Fluorouracil administration & dosage, Fluorouracil adverse effects, Humans, Leucovorin administration & dosage, Leucovorin adverse effects, Lung Diseases, Interstitial etiology, Lung Neoplasms secondary, Lung Neoplasms surgery, Male, Prednisolone administration & dosage, Antineoplastic Combined Chemotherapy Protocols adverse effects, Cholangitis, Sclerosing chemically induced, Lung Diseases, Interstitial chemically induced, Lung Neoplasms drug therapy
Published
2005

46. [Liver tuberculosis diagnosed using PCR-method on biopsied liver tissue].

Author

Tamba S, Kiriyama K, Sonoda T, Furubayashi T, Kato T, Tsubakio K, Shizusawa T, Matsushima N, Kanayama Y, and Himeno S

Subjects
Aged, Aged, 80 and over, Diagnosis, Differential, Humans, Male, Tuberculosis, Hepatic microbiology, Liver microbiology, Mycobacterium tuberculosis isolation & purification, Polymerase Chain Reaction methods, Tuberculosis, Hepatic diagnosis
Published
2003
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