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18 results on '"Hirasaki, Satoshi"'

3. Systolic Outward Motion of the Left Ventricular Apical Wall as Detected by Magnetic Resonance Tagging in Patients with Apical Hypertrophic Cardiomyopathy

Author

Tsukamoto, Masaki, primary, Hirasaki, Satoshi, additional, Kuribayashi, Toshiro, additional, Matsuo, Akiko, additional, Matsui, Hiroyuki, additional, Sawada, Takahisa, additional, Nakamura, Takashi, additional, Azuma, Akihiro, additional, Sugihara, Hiroki, additional, and Matsubara, Hiroaki, additional

Published
2006
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13. Improved Survival of Idiopathic Dilated Cardiomyopathy in the 1990s

Author

Azuma, Akihiro, primary, Matsuo, Akiko, additional, Nakamura, Takashi, additional, Kawasaki, Tatsuya, additional, Yamamoto, Kazuto, additional, Hyogo, Masayuki, additional, Hirata, Atsuhide, additional, Hirasaki, Satoshi, additional, Shima, Takatomo, additional, Sugihara, Hiroki, additional, Kunishige, Hiroshi, additional, Kuribayashi, Toshiro, additional, and Nakagawa, Masao, additional

Published
1999
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17. Rate-dependent QRS prolongation during exercise testing associated with hyperkalemia.

Author

Shiraishi H, Hyogo M, Ishibashi K, Urao N, Tsukamoto M, Keira N, Hirasaki S, Shirayama T, Nakagawa M, and Matsubara H

Subjects
Aged, Anti-Arrhythmia Agents pharmacology, Anti-Arrhythmia Agents therapeutic use, Exercise Test, Humans, Male, Mexiletine pharmacology, Mexiletine therapeutic use, Sodium Channel Blockers pharmacology, Ventricular Premature Complexes drug therapy, Electrocardiography, Heart Rate physiology, Hyperkalemia physiopathology
Abstract

The present case showed gradual increase of QRS duration from 100 ms up to 180 msec during an ergometer exercise test along with the heart rate increase. After exercise, QRS duration shortened and normalized. Laboratory test showed hyperkalemia (K = 8.0 mEq/l). T1 myocardial scintigraphy revealed exercise-induced transient ischemia in posterolateral region of left ventricle. Coronary angiography showed significant stenosis in the distal portion of left circumflex coronary artery. The increase of QRS duration was possibly due to the combination of hyperkalemia and the effect of mexiletine. The rate dependent blocking effect on sodium channel of mexiletine might be intensified under hyperkalemia.

Published
2004
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18. Idiopathic long QT syndrome with early afterdepolarization induced by epinephrine. Acase report.

Author

Urao N, Shiraishi H, Ishibashi K, Hyogo M, Tsukamoto M, Keira N, Hirasaki S, Shirayama T, and Nakagawa M

Subjects
Adrenergic alpha-Agonists pharmacology, Adrenergic alpha-Agonists therapeutic use, Electrocardiography drug effects, Epinephrine pharmacology, Female, Humans, Long QT Syndrome etiology, Methoxamine pharmacology, Methoxamine therapeutic use, Middle Aged, Pedigree, Epinephrine therapeutic use, Long QT Syndrome drug therapy, Membrane Potentials drug effects
Abstract

A patient with idiopathic long QT syndrome had repeated syncopal episodes. The QTc interval on the electrocardiogram at rest was 530 ms and was prolonged by exercise up to 740 ms with T wave alternation. Intravenous epinephrine (0.1 microg/kg weight per min), but not isoproterenol (0.7 microg/min), produced early after depolarization of the monophasic action potential recorded at the right ventricular apex. Epinephrine prolonged the QTc interval to 710 ms. After the addition of propranolol to the epinephrine, the QTc (580 ms) was longer than at baseline. Methoxamine also prolonged the QTc to 580 ms. The QT interval in long QT syndrome is generally considered to be prolonged by a beta-adrenergic effect, but in the present case alpha-adrenergic stimulation had an additional effect on the prolongation of the QT interval.

Published
2004
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