1,090 results on '"Hirst, Judy"'
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2. Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4−/− mouse
3. Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis
4. The antipsychotic medications aripiprazole, brexpiprazole and cariprazine are off-target respiratory chain complex I inhibitors
5. Mechanism of rotenone binding to respiratory complex I depends on ligand flexibility
6. Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes
7. Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy
8. Structure of the turnover-ready state of an ancestral respiratory complex I
9. Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation
10. Paracoccus denitrificans: a genetically tractable model system for studying respiratory complex I
11. Structural basis for a complex I mutation that blocks pathological ROS production
12. Quantum coherent contributions in biological electron transfer
13. Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I.
14. Maintained respiratory chain capacity in mice with severely reduced levels of mitochondrial respirasomes
15. Correlating functional and structural analysis of the complex I deactive transition in proteoliposomes
16. The structure of a catalytically inactive Paracoccus denitrificans complex I mutant under turnover conditions
17. Formation and Characterization of an All-Ferrous Rieske Cluster and Stabilization of the [2 Fe-2 S] 0 Core by Protonation
18. Correlating kinetic and structural data on ubiquinone binding and reduction by respiratory complex I
19. Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I
20. Structural insights into complex I deficiency and assembly from the disease-related ndufs4-/- mouse
21. The Enigma of the Respiratory Chain Supercomplex
22. Structure of inhibitor-bound mammalian complex I
23. Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I
24. Structural insights into respiratory complex I deficiency and assembly from the mitochondrial disease-related ndufs4-/- mouse.
25. Membrane-domain mutations in respiratory complex I impede catalysis but do not uncouple proton pumping from ubiquinone reduction
26. An inhibitor of oxidative phosphorylation exploits cancer vulnerability
27. Cryo-EM structures of complex I from mouse heart mitochondria in two biochemically defined states
28. Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes
29. Preserved respiratory chain capacity and physiology in mice with profoundly reduced levels of mitochondrial respirasomes
30. Small-volume potentiometric titrations: EPR investigations of Fe-S cluster N2 in mitochondrial complex I
31. Electron transport in redox enzymes
32. Tamoxifen reduces mitochondrial respiration, oncogenic signaling and mutant allele burden in a myeloproliferative neoplasm subset
33. Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides
34. Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
35. Using light scattering to assess how phospholipid–protein interactions affect complex I functionality in liposomes
36. Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments
37. Reverse Electron Transfer by Respiratory Complex I Catalyzed in a Modular Proteoliposome System
38. The Dichotomy of Complex I: A Sodium Ion Pump or a Proton Pump
39. Author response: Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
40. Making the leap from structure to mechanism: are the open states of mammalian complex I identified by cryoEM resting states or catalytic intermediates?
41. Cryo-EM structures of mitochondrial respiratory complex I fromDrosophila melanogaster
42. Membrane-domain mutations in respiratory complex I impede catalysis but do not uncouple proton pumping from ubiquinone reduction
43. Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I
44. Kinetic evidence against partitioning of the ubiquinone pool and the catalytic relevance of respiratory-chain supercomplexes
45. Open questions: respiratory chain supercomplexes—why are they there and what do they do?
46. CryoEM structures of respiratory complex I as a basis for understanding its function and mechanism
47. Ubiquinone-10 binding to mammalian respiratory complex I and conformational transitions associated with Q-site occupancy
48. Cryo-EM structures of minimal supercomplexes from alphaproteobacteria provide insights into mechanisms for efficient respiration
49. Elucidating the structure of Paracoccus denitrificans complex I, a model system for the mammalian enzyme, using lipid nanodiscs
50. Structural Basis of Mammalian Respiratory Complex I Inhibition by Medicinal Biguanides
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